Pearson Correlation Test Research Articles

The Comparative Study of Serum Estrogen and Lipid Profile in Pre- and Post-menopausal Women as Atherosclerosis Risk Factors in Pakistan.

Menopausesignifies the eternal termination of menstruation in women as a consequence of ovarian action loss, typically occurring around the age of 51 years. Cardiovascular disease is the leading cause of death among post-menopausal women, which may be due to lower levels of estrogen and lipid profile. The present study was undertaken to evaluate serum estrogen and lipid profile status to assess the risk of atherosclerosis in both pre- and post-menopausal women. The objective of this study is to explorethe relationship between estrogen and lipid levels of women in pre- and post-menopausal stages. A comparative cross-sectional study was conducted at Railway General Hospital Rawalpindi. A total of 100 participants were included of which 50 were pre-menopausal and 50 were post-menopausal women. Laboratory examination and questionnaires from the study population were used for data collection. Through the enzymatic method, serum cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein (HDL) were assessed. Serum very low-density lipoprotein (VLDL) levels were calculated via Friedwald's components VLDL=TG/5.0. An enzyme-linked immunosorbent assay kit was used for estrogen measurement. For statistical analysis, Student's t-test and the Pearson correlation test were used. Women after menopause have significantly high serum cholesterol, low-density lipoproteins, VLDLs, and triglycerides while HDL-c levels were significantly low (P<0.001). Levels of estrogen were low in post-menopausal females (P<0.001) as compared to menstruating women. Estrogen with HDL concentrations showed a positive correlation with an r value of 0.08556 while LDL levels showed a negative correlation with ar value of -0.26219. This comparative study explores the relationship between estrogen and lipid levels in pre- and post-menopausal women. Low estrogen with changed lipid variables was observed. Decreased cardiovascular protective HDL-c marks that menopause is a phase that acts as an independent risk factor for atherosclerosis.

Circ_0060060 Accelerates Metastasis of Non-Small-Cell Lung Carcinoma by Upregulating FUT8

We aimed to elucidate the diagnostic and prognostic values of Circ_0060060 in non-small-cell lung cancer (NSCLC), and its regulatory effect on FUT8. Relative levels of Circ_0060060 and FUT8 were examined in NSCLC and adjacent tissues. Clinical information of recruited NSCLC patients was collected for assessing the prognostic value of Circ_0060060. Regulatory effects of Circ_0060060 and FUT8 on in vitro proliferative and migratory abilities of NSCLC were examined by cell counting kit-8 (CCK-8) and transwell assay, respectively. Finally, the interaction between Circ_0060060 and FUT8 was determined via dual-luciferase reporter assay and Pearson correlation test. Circ_0060060 and FUT8 were upregulated in NSCLC tissues. High level of Circ_0060060 or FUT8 predicted higher incidences of distant metastasis and worse overall survival in NSCLC patients. in vitro evidences have shown the roles of Circ_0060060 and FUT8 in stimulating proliferative and migratory abilities of PC-9 and SPC-A1 cells. Circ_0060060 directly targeted FUT8 and positively regulated its level. Circ_0060060 and FUT8 are effective diagnostic markers of NSCLC. Circ_0060060 stimulates proliferative and migratory abilities of NSCLC by regulating FUT8.

Effect of neem leaf extract (Azadirachta indica) in reducing the degree of parasitemia and apoptosis in C57BL mice with cerebral malaria.

Brain malaria, which results from Plasmodium falciparum infection, is responsible for substantial fatalities and health issues. These processes, including cytoadherence, rosetting, and sequestration, induce an immune response, hypoxia, brain microvascular obstruction, disruption of the blood-brain barrier, and cell death. Parasitemia level can reveal the presence of infection and its association with apoptosis-related genes. Neem (Azadirachta indica) leaves with antimalarial properties could replace ineffective Indonesian malaria medications. This study was designed to evaluate the impact of neem leaf extract on cerebral malaria-induced parasitemia and neuron cell apoptosis in mice through an in vivo approach. 13-16 weeks old C57BL mice received infection by Plasmodium berghei strain ANKA. Parasitemia was estimated daily from the mice's tail blood. 8 mg, 12 mg, and 16 mg of a 96% ethanolic neem leaf extract were orally given for 6 days. Healthy, positive, and negative controls were included for treatment comparisons. On the 7th day, brain tissue was analyzed for (p > 0.05) gene expression. Through immunohistochemistry, both cell apoptosis in neurons expressing caspase-3 within a brain sample and the degree of parasitemia in a blood smear were assessed. The Pearson correlation test and one-way analysis of variance were employed to analyze the data. Neem leaf extract reduces parasitemia and neuron cell apoptosis at multiple dosages (p < 0.000). Apoptosis in brain neurons and parasitemia show a strong positive correlation (r = +0.939). Neem leaf extract at doses of 12 and 16 mg was the most effective in reducing parasitemia levels and causing cell death. Neem leaf therapy significantly reduced the degree of parasitemia and cell apoptosis in C57BL mice compared with the control group without treatment (p = 0.05). This shows that neem leaves have the potential to be a candidate drug for malaria.

Vitamin D in Type 2 Diabetes and Its Correlation With Heat Shock Protein 70, Ferric Reducing Ability of Plasma, Advanced Oxidation Protein Products and Advanced Glycation End Products.

To investigate the association between vitamin D3 level and oxidative stress biomarkers such as Heat Shock Protein 70 (HSP70), ferric reducing ability of plasma (FRAP), advanced oxidation protein products (AOPP) and advanced glycation end products (AGEs) in patients with Type 2 diabetes. In this cross-sectional study, 54 patients including 32 females and 22 males with a mean age of 54.92 ± 11.37 years with T2D attending the diabetes clinic from 2021 to 2022 were included. According to the average level of vitamin D in this population (14.91), they were divided into two groups with vitamin D ≤15 ng/mL and vitamin D >15 ng/mL. Multivariate regression analysis was conducted to evaluate the relationship between vitamin D and AOPP, HSP and FRAP parameters. The correlation between vitamin D and other variables was evaluated via the Pearson correlation test. Vitamin D level had a positive relation with FRAP (β = 0.32, p = 0.017) and HSP (β = 0.39, p = 0.003), but had a negative relation with AOPP (β = -0.30, p = 0.02). The level of 2hPP also had a negative relation with the level of vitamin D (β = -0.33, p = 0.03). There was not any relationship between the level of vitamin D and AGEs or other variables. After adjusting for multiple confounders for the multivariate regression model, HSP remained significant. This research indicates the relationship between vitamin D levels and oxidative stress biomarkers in patients with Type 2 diabetes.

Impacts of climate change on the potential distribution of Pulex simulans and Polygenis gwyni.

Pulex simulans and Polygenis gwyni are vectors of many flea-borne diseases. They were widely recorded in the United States and Mexico between 1970 and 2000. Maximum entropy models were used to explore the habitats of both fleas under different climate scenarios to provide the scientific basis for the surveillance and control of flea-borne diseases. We screened climate variables by principal component analysis and Pearson's correlation test and evaluated model performance by ROC curve. ArcMap was used to visualize expressions. Under current climatic conditions, the medium and highly suitable areas for P. simulans are estimated to be 9.16 × 106 km2 and 4.97 × 106 km2, respectively. These regions are predominantly located in South America, along the Mediterranean coast of Europe, the southern part of the African continent, the Middle East, North China, and Australia. For P. gwyni, the medium and highly suitable areas under current climatic conditions are approximately 4.01 × 106 and 2.04 × 106 km2, respectively, with the primary distribution in North China extending to the Himalayas, near the Equator in Africa, and in a few areas of Europe. Under future climate scenarios, in the SSP3-7.0 scenario for the years 2081-2100, the area of high suitability for P. simulans is projected to reach its maximum. Similarly, in the SSP2-4.5 scenario for 2061-2080, the area of high suitability for P. gwyni is expected to reach its maximum. Under global climate change, there is a large range in the potential distribution for both fleas, with an overall upward trend in the area of habitat under future climate scenarios. Governments should develop scientific prevention and control measures to prevent the invasive alien species flea.

Feasibility, reliability and satisfaction of (automated) capillary carcinoembryonic antigen measurements for future home-based blood sampling: the prospective CASA-I study.

Follow-up for colorectal cancer (CRC) necessitates regular monitoring of carcinoembryonic antigen (CEA) at the hospital. Capillary home-based blood collection, including minimally invasive techniques such as lancet sampling or an automated upper arm device (TAP-II), has the potential to replace a significant portion of hospital-based blood sampling, thereby enhancing self-reliance and quality of life. The objectives of this study were to assess the feasibility, reliability and preference for CEA blood collection. Baseline venous and capillary (by lancet and TAP-II) blood samples were collected from 102 participants, including 20 CRC patients with elevated CEA levels, 60 CRC patients undergoing postoperative outpatient monitoring and 20 healthy volunteers. The second group performed capillary blood collections at home on two consecutive follow-up appointments and subsequently sent them to the hospital. Satisfaction was assessed via patient reported outcome measures on pain, burden, ease of use and preference. The Pearson's correlation test of all usable samples resulted in a linear coefficient of 0.998 (95% CI 0.997-0.998) for the TAP-II method and 0.997 (95% CI 0.996-0.998) for the lancet method, both compared to venipuncture. Following the initial blood collection, 86% of the participants (n = 102) favoured the TAP-II, rating it as the least painful and burdensome option. After two home-based blood samples, the preference for the TAP-II method persisted, with 64% of the patients endorsing its use. This study demonstrated the feasibility of home-based capillary sampling of CEA. The TAP-II blood collection is the most reliable method and is preferred by patients over venipuncture and lancet sampling.

Is There a Direct Effect Between the Plication of the Myoaponeurotic Layer and the Force of Inspiratory and Expiratory Muscles After Abdominoplasty?

Abdominoplasty may generate an increase in the intra-abdominal pressure (IAP) and consequently an alteration in the pulmonary ventilation. The purpose of this study was to evaluate the potential alterations in the maximal static inspiratory pressure (MIP) and maximal static expiratory pressure (MEP) after abdominoplasty. Thirty-three female patients, aged between 18 and 60, with type III/B Nahas abdominal deformity that underwent abdominoplasty with plication of the anterior rectus and external oblique aponeurosis were selected. The MIP and MEP were measured using a mouthpiece. This is a simple way to indirectly gauge inspiratory and expiratory muscle strength. Measurements were performed before surgery and on the 2nd, 7th, 15th, and 180th postoperative day. In addition, IAP was measured before abdominoplasty and after the placement of compression garment. The MIP and MEP were compared using analysis of variance, followed by the Bonferroni multiple comparison test pairing the different points in time. Paired Student's t test was used for comparing IAP measurements. Pearson's correlation test was used to compare MIP and MEP variations with IAP variation. Results were considered statistically significant when P ≤ 0.05. A decrease was observed in MEP on the 2nd day, with a return close to normal values on the 15th day. In opposition MIP had a surprisingly increase on the 15th postoperative day (129 cmH2O), normalizing 180 days after the operation. A leap in IAP values was revealed at the end of the surgical procedure. It was not possible to establish a positive correlation between the increase of IAP and the alterations of MIP and MEP. There is a decrease in maximum expiratory pressure on the very early postoperative day (2nd postoperative day) and an increase in maximum inspiratory pressure on the 15th postoperative day in patients who underwent abdominoplasty. There was no correlation between the IAP and maximum respiratory pressure variations, both inspiratory and expiratory.

Role of squamous cell carcinoma antigen (SCC-Ag) in the management of carcinoma cervix in an Indian population: A pilot study

BackgroundEarly detection of recurrence in carcinoma cervix can be challenging but has the potential to improve survival in a subset of patients. Squamous cell carcinoma antigen (SCC-Ag) has been tested in multiple roles in the management of cervical cancer but the evidence from India is limited. MethodsThis was a prospective, cohort pilot study conducted in a tertiary care hospital in central India. Study subjects were patients with locally advanced carcinoma cervix treated with concurrent chemoradiotherapy between June 2017 and May 2018. All patients underwent pre and post-treatment SCC-Ag testing which was continued serially every 3 months for a total follow-up of 24 months. A cut-off value of 1.5 ng/ml or more was used to define a positive test. Chi–Square tests, Pearson's correlation testing and Kaplan Meier plots were used to study the association of different patient and tumour variables with the SCC-Ag levels. Test validity of serial measurements of SCC-Ag was also measured for detection of recurrence. ResultsA total of 45 patients were included. SCC-Ag levels were strongly correlated with tumour stage and presence of lymph nodal metastases. Post-treatment abnormal SCC-Ag levels were significantly associated with a poorer recurrence-free survival (RFS). Serial measurement of SCC-Ag levels proved to be a good screening tool for early detection of recurrences even before clinical symptoms or signs developed with a sensitivity of 90% and specificity of 91.8%. ConclusionOur study has highlighted the benefits of the use of this tumour marker in the management of cervical cancer and has generated useful evidence supporting its use in prognosticating patients, guiding investigations, determining risk for recurrence, assessing tumour response and for early detection of recurrences.

Social determinants of health and disparities in spine surgery: a 10-year analysis of 8,565 cases using ensemble machine learning and multilayer perceptron

BACKGROUND CONTEXTThe influence of SDOH on spine surgery is poorly understood. Historically, researchers commonly focused on the isolated influences of race, insurance status, or income on healthcare outcomes. However, analysis of SDOH is becoming increasingly more nuanced as viewing social factors in aggregate rather than individually may offer more precise estimates of the impact of SDOH on healthcare delivery. PURPOSEThe aim of this study was to evaluate the effects of patient social history on length of stay (LOS) and readmission within 90 days following spine surgery using ensemble machine learning and multilayer perceptron. STUDY DESIGNRetrospective chart review. PATIENT SAMPLE8,565 elective and emergency spine surgery cases performed from 2013 to 2023 using our institution's database of longitudinally collected electronic medical record information. OUTCOMES MEASURESPatient LOS, discharge disposition, and rate of 90-day readmission. METHODSEnsemble machine learning and multilayer perceptron were employed to predict LOS and readmission within 90 days following spine surgery. All other subsequent statistical analysis was performed using SPSS version 28. To further assess correlations among variables, Pearson's correlation tests and multivariate linear regression models were constructed. Independent sample t-tests, paired sample t-tests, one-way analysis of variance (ANOVA) with post-hoc Bonferroni and Tukey corrections, and Pearson's chi-squared test were applied where appropriate for analysis of continuous and categorical variables. RESULTSBlack patients demonstrated a greater LOS compared to white patients, but race and ethnicity were not significantly associated with 90-day readmission rates. Insured patients had a shorter LOS and lower readmission rates compared to non-insured patients, as did privately insured patients compared to publicly insured patients. Patients discharged home had lower LOS and lower readmission rates, compared to patients discharged to other facilities. Marriage decreased both LOS and readmission rates, underweight patients showcased increased LOS and readmission rates, and religion was shown to impact LOS and readmission rates. When utilizing patient social history, lab values, and medical history, machine learning determined the top 5 most-important variables for prediction of LOS —along with their respective feature importances—to be insurance status (0.166), religion (0.100), ICU status (0.093), antibiotic use (0.061), and case status: elective or urgent (0.055). The top 5 most-important variables for prediction of 90-day readmission—along with their respective feature importances—were insurance status (0.177), religion (0.123), discharge location (0.096), emergency case status (0.064), and history of diabetes (0.041). CONCLUSIONSThis study highlights that SDOH is influential in determining patient length of stay, discharge disposition, and likelihood of readmission following spine surgery. Machine learning was utilized to accurately predict LOS and 90-day readmission with patient medical history, lab values, and social history, as well as social history alone.

Single nucleotide polymorphisms of GEMIN3 modify the risk of primary Sjögren's syndrome in female patients

BackgroundMicroRNA (miRNA)-processing machinery may modify the risk of primary Sjögren's syndrome (pSS) by altering miRNA expression profiles. Inflammatory cytokines and reactive oxygen species (ROS) are also involved in pSS; however, the role of altered miRNAs expression in its pathogenesis is still unclear. We aimed to evaluate the relationship between single-nucleotide polymorphisms (SNPs) in miRNA processing machinery genes, including XPO5 (rs11077), RAN (rs14035), Dicer (rs3742330), TNRC6B (rs9623117), GEMIN3 (rs197412), and GEMIN4 (rs2740348), and the risk of pSS in female patients. The potential associations of cytokines and ROS with pSS-susceptible SNPs were also evaluated. Materials and MethodsThe SNPs confirmed by polymerase chain reaction ligase detection reaction were genotyped in 74 female patients with pSS and 77 controls. The relationship was analyzed by Student's t-test, Wilcoxon rank-sum test, chi-square test, Pearson's correlation test, and binary logistic regression analysis. ResultsFor rs197412 of the GEMIN3 gene, the genotype TT carrier was associated with a 2.172-fold increased risk for pSS when compared with that of CT+CC carrier (odds ratio: 2.172, 95% CI, 1.133–4.166, p=0.019). Simultaneously, the pSS-susceptible TT carriers were associated with increased interferon-γ (IFN-γ) (P < 0.001) and tumor necrosis factor-α (TNF-α) (P = 0.003) levels when compared with that of CT+CC genotype carriers in female patients with pSS. The subsequent analysis also showed a weak positive correlation between IFN-γ and TNF-α levels (r=0.271, P = 0.019). ConclusionThe predictors of GEMIN3 SNPs might modify pSS development in females by mediating the expression of miRNAs and therefore regulate the levels of IFN-γ and TNF-α.

Tumor hypoxia in immune infiltration and prognosis of bladder cancer.

Bladder cancer (BC) is the sixth most common cancer and the ninth leading cause of cancer death among men in the world. Previous studies have shown that tumor hypoxia plays an important role in the occurrence and development of BC, but the role of tumor hypoxia in the prognosis and immune infiltration of BC remains unclear. Our aim was to perform a bioinformatics analysis combined with a clinical analysis to explore the roles of hypoxia in BC. We acquired datasets (GSE13507, GSE5287, and GSE1827) containing mRNA expression information from BC cohorts from the Gene Expression Omnibus (GEO) and measured the Hypoxia score using the Gene Set Variation Analysis (GSVA). Then we used X-tile method and log-rank test and Pearson's correlation test to analyze the relation among the Hypoxia score and the clinicopathological and immunological characteristics of BC and used stepwise Cox regression analysis to establish a Prognostic model. Hypoxia was found to be closely associated with tumor grade, pathological type, invasion, and prognosis of BC in our study. Moreover, we determined that hypoxia was closely related to the infiltration abundance of multiple immune cells through a correlation analysis, and the tumor immune cell infiltration was further found to be significantly associated with the tumor grade and tumor type of BC. Furthermore, we constructed several models based on the Hypoxia score and tumor immune infiltration with C-indexes ranging from 0.703 and 0.888, which showed good performance in predicting the prognosis of BC. Our study showed that hypoxia plays an important role in the progression, prognosis, and tumor immune infiltration of BC. Our models based on hypoxia and tumor immune infiltration play a guiding role in the prognosis and treatment of BC patients.

The relationship between physical activity level, digital game addiction, and academic success levels of university students

This study examined the relationship between physical activity, digital game addiction, and academic success among university students. Participants were university 704 students from Turkiye who did physical activity and played digital games. The sample group consisted of 704 university students (342 women and 362 men), selected through random sampling. Data were collected using demographic information forms, a digital game addiction scale, and an international short-form questionnaire about physical activity. The data were analyzed using Pearson correlation, t-tests, one-way ANOVA, and post-hoc tests. The findings revealed a significant negative relationship between academic success and both physical activity and digital game addiction. Men exhibited higher levels of digital game addiction compared to women, but there was no significant gender difference in physical activity levels. Students who were categorized as academically successful had lower levels of both digital game addiction and physical activity.

Spatial Assessment of the Effect of Income on Healthcare Facilities Patronage in Kogi-East Senatorial District, Kogi State, Nigeria

This study assessed the level of income on health facility patronage in Kogi East, Kogi State, Nigeria. Primary data necessary for this study were collected from patients, health workers and residents of Kogi East through the administration of questionnaires, personal observations and obtaining of satellite imageries for creation of digital health facilities distribution map of the study area, while the secondary sources includes published documents. A total of 400 questionnaires were administered; however, only 395 were returned for analysis. Results were presented in both tables and charts while the hypothesis was tested using Correlation Analysis. Findings from this research revealed that majority of the respondents (58.80%) do not patronize any health facilities due to the high cost of treatment. The study also found that the major illness that affects respondents in Anyigba is Malaria Fever (76.5%); the result also shows 87.5% of the respondents disclosing that money has prevented them from patronizing health facilities. The study further found that the socio-economic characteristics of the residents/patients play a significant role in determining the frequency of visits to healthcare facilities; this is substantiated with the Pearson correlation test result that revealed a significant relationship between patronage pattern and monthly income of the respondents. This research also revealed that the lower the incomes of an individual, the limited access such individual would have to health facilities and vice versa. Given the z-score of 0.288134438445, the distribution pattern of the health facilities does not appear to be significantly different than random, as the healthcare facilities map also support the above claim. It is therefore recommended that efforts should be put in place to improve the socio-economic status of individuals so as to improve their access and utilization of healthcare facilities. Government at all levels as well as the organized private sector should carry out massive public awareness on the importance of health insurance scheme.

Management of Cardiovascular Disease Patients with Periodontitis Requiring Dental Treatment – A KAP Study among Dental Students

ABSTRACT Background: It is frequently observed that dental students require so many consents to manage medically compromised patients, especially cardiovascular patients with periodontitis requiring dental treatment. Aims and Objectives: The present study aimed to assess the dental students’ knowledge, attitudes, and practices regarding the management of cardiovascular disease (CVD) patients with periodontitis requiring dental treatment. Material and Methods: The cross-sectional study was conducted among 611 dental undergraduate and postgraduate students (branches of Periodontology, Oral and Maxillofacial Surgery, Oral Medicine and Radiology, Endodontics, Prosthodontics, and Public Health and Dentistry) of central Gujrat. Self-administered structured questionnaires with 23 questions were distributed in pen-and-paper physical format. Statistical analysis for descriptive statistics like frequency, percentage, mean, standard deviation, confidence interval, one-way analysis of variance, post hoc test for multiple comparisons, Fisher’s exact test, and Pearson’s correlation has been done by MS Excel and STATA/IC-13. Results: As per the post hoc test, both groups of students have significantly different knowledge (-4.20210*, P = 0.028) and their practices (0.68632, P = 0.968) but no significant difference between their attitudes (-6.22828, P = 0.089). According to the Pearson correlation test, a weak positive/no relationship between knowledge, attitudes, and practice is reported in both study groups. There is a weak positive relation between knowledge and attitudes (0.270) and between knowledge and practices (0.121), and a similar relationship between their attitudes and practices (0.172) was observed in both groups. Conclusion: Correct knowledge, attitudes, and practices regarding dental management of CVD patients with periodontitis can reduce medical consent to improve the treatment quality of dental students.

The Influence of Providing Information and Educational Media in Efforts to Prevent Stroke

Stroke is the leading cause of physical and mental disability worldwide. In Indonesia, the incidence of stroke is alarmingly high, affecting approximately 10.9% of the population annually, with around 713,783 individuals experiencing stroke each year. Understanding how to prevent stroke is crucial. Clear and regular information, along with effective educational media, are essential for increasing public awareness of stroke. This study aims to determine the impact of social media and knowledge on stroke prevention. This type of study is a non-experimental quantitative study using a cross-sectional. This study is conducted in portions, with patients who are willing and able to talk effectively. Univariate, bivariate, and multivariate analyses were conducted using Pearson correlation tests and linear regression tests. The results show that among the 100 respondents, most were male, aged 41-60 years, and engaged in the best stroke prevention efforts. The Pearson correlation test showed significant correlations between information accuracy, frequency, and educational media for stroke prevention (Pearson p=0.89; p=0.62; p=0.75). The linear regression test revealed that the clarity of information, frequency of information, and educational media together increased stroke prevention efforts (p=0.037), with the clarity of information being the most significant factor. The conclusion is the study concludes that educational media and accurate information are crucial in preventing stroke. It is recommended that the Kasih Sayang Clinic conducts comprehensive stroke education and screening every six months to enhance prevention efforts.

Stigma of mental health and attitude towards psychological help-seeking behaviour among students of a health science institute in Karnataka: a cross-sectional study

Background: Mental health illnesses are becoming a prime cause of concern among young adults. Many individuals with mental disorders do not get the necessary health care. Objectives: To assess the attitude towards seeking professional psychological help and stigma of mental illness among the students of a health science institute, to assess the association between stigma and attitude towards seeking psychological help with select socio demographic variables and to determine the correlation between attitude towards seeking professional psychological help and stigma of mental illness. Methods: A cross-sectional study was done on 215 students in Karnataka. The study tool consisted of questionnaires on socio-demographic profile and two sets of validated scales (Attitude Toward Seeking Professional Psychological Help Scale and Perceived Devaluation Discrimination Scale). Results: The study showed males had more positive attitude towards seeking professional psychological help than females. Individuals with history of present/past illness were more open towards seeking professional psychological help. Pearson correlation test between ATSPPHS and PDDS showed a negative correlation. Conclusions: Psychological help seeking attitude needs to be improved among the students. Educational institutes need to incorporate mental health awareness and stigma reduction program in their curriculum.

Technology Acceptance Model (TAM) -Based Assessmentof User Acceptance for a Smart Crop Management System

A smart system that can monitor critical growth parameters and control irrigation and fertilizer applications for tomato production was developed to answer the need for a better and data-driven farm management. The technology was then introduced to tomato farmers in one of the project sites. Technology Acceptance Model (TAM) was used to assess the receptiveness of the farmers to the developed technology focusing on two (2) key predictors: perceived usefulness (PU) and perceived ease of use (PEU). A questionnaire based on TAM principles was formulated for a self-administered survey to assess participants’ perceptions and opinions about the developed technology. The reliability of the questionnaire was validated using Cronbach’s alpha with a value of 0.93 and 0.96 for PU and PEU, respectively. The PU and PEU scores were found to be 94.83% and 88.41%, respectively. The PU score classified the developed technology as very useful while the PEU score categorized it as very easy to use. A Pearson correlation test was also conducted to investigate if there is a linear relationship between PU and PEU. Results showed that there is a statistically significant positive linear relationship between the two predictors. Several issues were pointed out during the conduct of the technology demonstration that might affect the perception of the farmer group towards the developed technology. Nonetheless, it was concluded that the farmers are indeed receptive and interested with the technology, and their appreciation of the benefits it entails to their livelihood is evident.

Body Fat Percentage Prediction Model of Female Republic of Indonesia Defense University Cadet

The incidence of obesity among female adolescents and adults continues to rise in Indonesia, posing significant health risks, such as cardiovascular diseases. Female cadets at the Republic of Indonesia Defense University (RIDU) are reserve members in national defense, and their performance is correlated with their nutritional status; therefore, their nutritional status should be closely monitored. Anthropometric examination is a method for nutritional assessment that incorporates body fat percentage (BFP) as part of body composition analysis. Predictive models for BFP can help identify obesity rates within a population. In Indonesia, no research has focused on BFP prediction models specifically for female RIDU cadets. This study aimed to develop a model to estimate BFP in this group. Conducted in August 2021, the research employed a quantitative cross-sectional approach involving 108 female students aged 18 to 20 from RIDU who met the inclusion and exclusion criteria. The study analyzed the relationship between BFP (measured by bioelectrical impedance analysis, or BIA) and independent variables such as age, body mass index (BMI), and waist circumference (WC). Pearson correlation tests and multivariate linear regression were used to create the prediction model. Findings showed an average BFP of 28.303% ± 6.37%. BMI had the strongest correlation with BFP (r = 0.722). The resulting predictive model is BFP = -94.055 + 39.064*WC + 1.073*age + 1.420*BMI, with an adjusted R square value of 0.535, indicating the model’s explanatory power. This study showed the first to predict BFP in female RIDU cadets. Age, BMI, and WC were predictors of BFP among female RIDU cadets.

Pengaruh Rasio Keuangan terhadap Harga Saham Rumah Sakit Privat yang Terdaftar di Bursa Efek Indonesia

Private Hospital is a health institution aimed at profit. Some of them even trade shares on the stock exchange to obtain additional capital. The literature that examines share price of hospitals is still limited. For this reason, this research aims to obtain empirical results regarding the effect of financial ratios on private hospital stock prices. This research was conducted in Indonesia with testing year 2016 to 2022. Data source was obtained from OSIRIS with SIC 806. Researchers used STATA14 to carry out statistical tests. The tests carried out are Pearson correlation test, Classical assumption test, and Multiple linear regression test. Results show that ROA has a positive effect on stock prices, but other financial ratios used in the model have no significant effect.

Salivary Biophysical Properties in Relation to Dental Caries Severity Among Type 1 Diabetic Children

Diabetes Mellitus is a multifactorial metabolic disorder characterized by elevated blood glucose levels or hyperglycemia. Diabetes Mellitus may cause many oral problems as a result of both micro- and macrovascular complications. We aimed to assess the probable relationship between the severity of dental caries and the biophysical properties of saliva (flow rate, PH, and viscosity). Materials and Methods: A cross-sectional comparative study was conducted in Karbala City, in which a sample of 45 children with type 1 diabetes aged between 10-12 years was compared with a group of 45 non-diabetic children matched in age and gender. Dental caries severity and experience were recorded and diagnosed using Manji et al.'s criteria and the decayed, missing, and filling index (DMFS/dmfs). Unstimulated salivary specimens were collected to evaluate flow rate, pH, and viscosity. Pearson (r) correlation coefficient test and one-way ANOVA test were employed for data analysis using SPSS-22. Results: Salivary levels of viscosity and flow rate were not statistically significant (P &gt; 0.05) predicators regarding the dental caries experience and severity among type1 diabetic children (controlled and uncontrolled) while pH level of saliva was a statistically significant predictor regarding dental caries experience (DS/ DMFT) among uncontrolled diabetic children. Conclusion: Compared to non-diabetic children, type 1 diabetic children exhibited pronounced changes in salivary biophysical properties but unpronounced changes in caries status.