Peak Knee Flexion Moment Research Articles

Gender Comparisons and Associations between Lower Limb Muscle Activation Strategies and Resultant Knee Biomechanics during Single Leg Drop Landings

(1) Background: We aimed to compare gender differences in knee biomechanics and neuromuscular characteristics, and to determine the relationships between lower limb muscle pre-activations and knee biomechanics during a single leg drop landing, in order to identify riskier landing patterns to prevent injury and intervene properly. (2) Methods: Descriptive laboratory cross-sectional study on 38 healthy untrained subjects with low to moderate physical activity status. (3) Results: During the initial-contact phase of landing, females demonstrated greater peak vertical ground reaction force (GRF) normalized to body weight (49.12 ± 7.53 vs. 39.88 ± 5.69 N/kg; p < 0.001; Hedge’s g = 1.37), peak knee anterior reaction force normalized to body weight (0.23 ± 0.04 vs. 0.17 ± 0.05 N/kg; p < 0.001; Hedge’s g = 1.33), and decreased pre-activation of the semitendinosus (45.10 ± 20.05% vs. 34.03 ± 12.05%; p = 0.04; Hedge’s g = 0.67). The final regression equation was peak knee anterior reaction force = 0.024 + 0.025 (peak knee flexion moment) − 0.02 (semitendinosus-to-vastus lateralis pre-activation ratio) + 0.003 (peak vertical GRF) (R2 = 0.576, p < 0.001). (4) Conclusions: Overall, the data provided in this study support that a reduced semitendinosus-to-vastus lateralis pre-activation ratio predicted an increase in knee anterior reaction force and potentially an increase in ACL forces. Female non-athletes had gender-specific landing characteristics that may contribute to ACL injury. Future studies are warranted to consider more possible predictors of non-contact ACL injury.

Patellofemoral contact forces and knee gait mechanics 3 months after ACL reconstruction are associated with cartilage degradation 24 months after surgery

Evaluate patellofemoral cartilage health, as assessed by quantitative magnetic resonance imaging (qMRI) T2 relaxation times, 24-months after ACL reconstruction (ACLR) and determine if they were associated with patellofemoral contact forces and knee mechanics during gait 3 months after surgery. Thirty individuals completed motion analysis during overground walking at a self-selected speed 3 months after ACLR. An EMG-driven neuromusculoskeletal model was used to determine muscle forces, which were then used in a previously described model to estimate patellofemoral contact forces. Biomechanical variables of interest included peak patellofemoral contact force, peak knee flexion angle and moment, and walking speed. These same participants underwent a sagittal bilateral T2 mapping qMRI scan 24-months after surgery. T2 relaxation times were estimated for both patellar and trochlear cartilage. Paired t-tests were used to compare T2 relaxation times between limbs while Pearson correlations and linear regressions were utilized to assess the association between the biomechanical variables of interest and T2 relaxation times. Prolonged involved limb trochlear T2 relaxation times (vsuninvolved) were present 24-months after surgery, indicating worse cartilage health. No differences were detected in patellar cartilage. Significant negative associations were present within the involved limb for all the biomechanical variables of interest 3 months after ACLR and trochlear T2 relaxation times at 24-months. No associations were found in patellar cartilage or within the uninvolved limb. Altered involved limb trochlear cartilage health is present 24-months after ACLR and may be related to patellofemoral loading and other walking gait mechanics 3 months after surgery.

Muscle activation timing and knee biomechanics during single leg hop in subjects with and without anterior cruciate ligament reconstruction: a case study

The Single Leg Hop test (SLHT) is commonly performed to determine readiness to return to sport (RTS) after anterior cruciate ligament (ACL) injury and reconstruction [1]. Usually, the between-limb symmetry of hop distance is considered as a criterion to clear the athletes to RTS. However, athletes may pass this criterion despite ongoing biomechanical and neuromuscular deficits. Several works developed an instrumented approach of the SLHT to assess biomechanical parameters associated to ACL injury risk [1]. Although it is known that muscle pre-activation timing during landing can be altered in patients with ACL reconstruction (ACLR) [2], thus exposing them to a reinjury risk, very few studies have related biomechanical parameters with electromyographic (EMG) signals of the involved muscles. The aim of this preliminary study is to assess muscle pre-activation timing prior to SLHT landing in both ACLR and HC athletes and to associate this information with ACL injury-related kinematic and kinetic parameters. Two male soccer athletes (Tegner Activity Score ≥ 6) participated in the study, one healthy (HC) and one with ACLR (12 months before the test; injured limb: left). They performed three SLHT landing on a force plate (AMTI, USA, 1000 Hz) after standardized warm-up. The 3D trajectories of 52 markers were measured by an optoelectronic system (Vicon, 200 Hz) [3]. Eight wireless bipolar EMG electrodes (MiniWave, Cometa, Italy) were placed on Vastus Medialis (VM), Vastus Laterialis (VL), Semitendinous (ST) and Biceps femoris (BF) on both limbs according to the SENIAM guidelines [4]. All instruments were electronically synchronized. Foot-force plate contact was identified by setting a threshold of 20 N on the vertical GRF (vGRF) [5]. EMG onset prior to landing was identified according to [2]. A set of ACL injury risk-related parameters were then extracted: peak vGRF (vGRF peak ), peak knee flexion and abduction moment (KMflex peak KMabd peak ), and knee flexion at initial contact (KflexIC). Also, for each SLHT, the hop distance was assessed (SLH dist ). The Limb Symmetry Index (LSI) was then calculated for each parameter. For each athlete and each limb, the SLH with the greater hopping distance was considered for further data processing. Muscle pre-activation timing was shorter in ACLR subject than HC in all muscles (Table 1). ACLR subject also showed higher values in peak knee moments, especially in the injured limb, as well as greater asymmetry for most of the investigated parameters, especially knee angles and moments. In the ACLR subject, the lower muscle pre-activation timing prior to landing may lead to an uncoordinated movement and to a deficit in muscle force generation to stabilize the joint, thus increasing knee injury risk [2]. This timing was even shorter in the injured limb. From a biomechanical point of view, a greater asymmetry was found in the ACLR subject with respect to the HC in both kinematic and kinetic parameters. On the contrary, hop distance LSI did not show any clear difference between the two participants. These results corroborate the hypothesis that evaluating only hop distance is reductive.

Bone-Patellar Tendon-Bone Autograft Harvest Prolongs Extensor Latency during Gait 2 yr after ACLR.

Bone-patellar tendon-bone (BPTB) graft harvest for anterior cruciate ligament reconstruction alters patellar tendon properties, which inflict poor quadriceps neuromuscular function. BPTB autografts are associated with higher rates of posttraumatic osteoarthritis, which in turn is associated with pathological gait. The purpose of this study was to investigate the latency between the time of peak quadriceps activity and the peak knee flexion moment during gait, between those with BPTB grafts ( n = 23) and other graft types (hamstring autograft or allografts, n = 54), 5 ± 2 months and 2 yr (25 ± 3 months) after anterior cruciate ligament reconstruction. We hypothesized that longer latencies would be observed in the BPTB graft group in the involved limb. We expected latencies to shorten over time. Knee moments and quadriceps EMG were collected during gait, and vastus medialis, vastus lateralis, rectus femoris (RF), and quadriceps latencies were calculated. Linear mixed-effects models were used to compare latencies between graft types and over the two time points. The main effects of graft type were observed for vastus medialis ( P = 0.005) and quadriceps ( P = 0.033) latencies with the BPTB graft group demonstrating longer latencies. No main effects of graft type were observed for vastus lateralis ( P = 0.051) and RF ( P = 0.080) latencies. Main effects of time were observed for RF latency ( P = 0.022). Our hypothesis that the BPTB graft group would demonstrate longer extensor latency was supported. Contrary to our second hypothesis, however, latency only improved in RF and regardless of graft type, indicating that neuromuscular deficits associated with BPTB grafts may persist 2 yr after surgery. Persistent deficits may be mediated by changes in the patellar tendon's mechanical properties. Graft-specific rehabilitation may be warranted to address the long-term neuromechanical deficits that are present after BPTB graft harvest.

Effect of Fatigue on Hip and Knee Joint Biomechanics in Anterior Cruciate Ligament Deficient Patients

The influence of fatigue on landing biomechanics in anterior cruciate ligament deficient (ACLD) patients is poorly understood. The purpose of this study was to examine the effect of fatigue on hip and knee joint biomechanics in deficient patients. Twelve ACLD males and 12 healthy control subjects participated in the study. The ACLD patients landed with increased peak knee flexion angle (F = 15.71, p < .01) and decreased peak knee flexion moment (F = 9.13, p < .01) after fatigue. Furthermore, ACLD patients experienced lower vertical ground reaction forces compared with controls regardless of fatigue state (F = 9.75, p < .01). It seems that ACLD patients use protective strategy in response to fatigue in order to prevent further injury in knee point.

EFFECTS OF STEP WIDTH MODIFICATIONS ON KNEE KINETICS OF PATIENTS WITH MEDIAL KNEE OSTEOARTHRITIS WALKING WITH A DECREASED FOOT PROGRESSION ANGLE

Purpose: Gait retraining strategies are being developed worldwide to improve the mechanical loading of knee joints with medial osteoarthritis (OA). A dual kinetic change (DKC), aimed to decrease the peak knee adduction moment (pKAM) by at least 10% without increasing the peak knee flexion moment (pKFM), is particularly sought in this case. Interesting results have been obtained by instructing the patients to modify their footprint parameters, particularly reducing the foot progression angle (FPA), a modification also known as toeing-in, and more recently, by modifying step-width (SW).

Identifying Gait Pathology after ACL Reconstruction Using Temporal Characteristics of Kinetics and Electromyography.

Asymmetrical gait mechanics after anterior cruciate ligament reconstruction (ACLR) are associated with the development of posttraumatic knee osteoarthritis. Current measures of gait mechanics have focused heavily on peak magnitudes of knee kinematics, kinetics, and joint contact forces but have seldom considered the rate of knee loading, cumulative knee load, or the timing of motor input surrounding peaks. The purpose of this study was to introduce and describe novel metrics of gait using temporal characteristics of kinetics and EMG to identify neuromuscular deficits of the quadriceps in patients after ACLR. Gait mechanics were assessed 6 months (n = 145) and 24 months (n = 116) after ACLR. External knee flexion rate of moment development (RMD) and knee flexion moment impulse (KFMI) leading up to the time of peak knee flexion moment (pKFM), peak RMD between initial contact to pKFM, and cumulative KFMI were calculated. Extensor latencies from the quadriceps, vastus medialis, vastus lateralis, and rectus femoris (time of pKFM - time of peak EMG activity) during the weight acceptance phase of gait were also calculated. Paired-sample t-tests (α = 0.05) were performed between limbs at both time points. Slower RMD, smaller KFMI, and longer extensor latencies in the involved compared with uninvolved limb were observed across all measures at 6 months (P < 0.005). At 24 months, RMDpeak was slower, and KFMI50ms, KFMI100ms, and KFMItotal were lower in the involved limb (P < 0.003), but no other asymmetries were found. Slower RMD, smaller KFMI, and prolonged extensor latencies may characterize neuromuscular deficits underlying aberrant gait mechanics early after ACLR. RMD, KFMI, and extensor latencies during gait should be considered in the future to quantify asymmetrical movement patterns observed after ACLR and as markers of recovery.

Association Between Knee Moments During Stair Navigation and Participant-Related Factors in Individuals With Anterior Cruciate Ligament Reconstruction: A Cross-Sectional Study.

Altered knee joint mechanics may be related to quadriceps muscle strength, time since surgery, and sex following anterior cruciate ligament reconstruction (ACLR). The aim of this study was to investigate the association between knee moments, with participant-related factors during stair navigation post-ACLR. Cross-sectional study. A total of 30 participants (14 women) with ACLR, on average 7.0 (SD 4.4) years postsurgery were tested during stair ascent and descent in a gait laboratory. Motion capture was conducted using a floor-embedded force plate and 11 infrared cameras. Quadriceps concentric and eccentric muscle strength was measured with an isokinetic dynamometer at 60°/s, and peak torques recorded. Multiple regression analyses were performed between external knee flexion and adduction moments, respectively, and quadriceps peak torque, sex, and time since ACLR. Higher concentric quadriceps strength and female sex accounted for 55.7% of the total variance for peak knee flexion moment during stair ascent (P < .001). None of the independent variables accounted for variance in knee adduction moment (P = .698). No significant associations were found for knee flexion and adduction moments during for stair descent. Higher quadriceps concentric strength and sex explains major variance in knee flexion moments during stair ascent. The strong association between muscle strength and external knee flexion moments during stair ascent indicate rehabilitation tailored for quadriceps may optimize knee mechanics, particularly for women.

A novel pivot ankle/foot prosthesis reduces sound side loading and risk for osteoarthritis: a pragmatic randomized controlled trial.

Background:Individuals with unilateral transtibial amputation are at risk of abnormal mechanical joint loading and development of osteoarthritis on sound side joint structures.Objectives:This study describes the spatiotemporal and kinetic and kinematic parameters related to osteoarthritis in participants while using (A) a solid-ankle cushioned-heel prosthesis (SACH), (B) a conventional energy storage and return (ESAR) foot prosthesis, and (C) a novel ESAR (N-ESAR) foot prosthesis.Study design:A pragmatic randomized controlled trial.Methods:K3–K4 ambulators used three feet in a 2-week randomized cross-over order. Kinetics of vertical ground reaction forces (vGRFs) and 3D kinematics of joint angles were integrated to provide normalized parameters. Data were analyzed using one way and mixed model Analysis of variance (ANOVAs) (p < 0.05) and Cohen d statistic.Results:Twenty participants, aged 40 ± 16 years with body mass index of 24.7 ± 3.6 kg/m2, experienced minimal change in the spatiotemporal parameters between feet. Participants using the N-ESAR foot prosthesis experienced reduced peak knee external adduction moment (p = 0.030), peak vGRFs (p < 0.001), and peak loading rate of vGRFs (p = 0.030). Peak knee flexion moments only changed when using the solid-ankle cushioned-heel prosthesis, in a positive direction (p = 0.014). Using the N-ESAR prosthesis also increased peak distal shank power during late stance phase (p < 0.001).Conclusions:A novel ankle/foot ESAR prosthesis reduces loading on the sound side. With extended use of the N-ESAR foot prosthesis, these findings may provide the prosthesis user with improved outcomes related to sound side loading and development of osteoarthritis.

Associations Between Cadence and Knee Loading in Patients With Knee Osteoarthritis.

To test the hypothesis that higher walking cadence is associated with lower knee loading, while controlling for walking speed, in patients with medial compartment tibiofemoral osteoarthritis (OA). A total of 691 patients underwent quantitative gait analysis, including 3-dimensional knee moments and temporospatial parameters. Using multivariate linear regression, we tested the association of walking cadence with the knee adduction moment angular impulse (a surrogate measure of medial knee compartment load throughout the stance), while controlling for walking speed. We repeated the analysis while also adjusting for sex, age, body mass index, radiographic OA, knee pain, lateral trunk lean, foot progression angle, and mechanical axis angle, and while replacing the knee adduction moment angular impulse with other surrogate measures of knee loading. While controlling for walking speed, we found that a lower cadence was associated with higher knee adduction moment angular impulse (standardized β = -0.396, P < 0.001), suggesting a 0.02% body weight × height × seconds (%BW × Ht × s) decrease in impulse for each step per minute increase in cadence (unstandardized β -0.020 %BW × Ht × s [95% confidence interval -0.027, -0.015]), and remained consistent after adjusting for covariates. A lower cadence was also associated with higher first (standardized β = -0.138, P = 0.010) and second peak knee adduction moment (standardized β = -0.132, P = 0.018), higher peak knee flexion moment (standardized β = -0.128, P = 0.049), and vertical ground reaction force (standardized β = -0.116, P = 0.035) in the adjusted analyses. When controlling for walking speed, we found that a lower cadence is associated with higher knee loading per step in patients with medial tibiofemoral OA. Future research should investigate the potential beneficial biomechanical and clinical effects of increasing walking cadence in patients with knee OA.

Effects of step width modifications on the ambulatory kinetics in patients with medial knee osteoarthritis

Purpose: Gait retraining is a promising intervention to improve the mechanical loading of the knee in patients with medial osteoarthritis (OA). Specifically, it could reduce the peak knee adduction moment (pKAM) without increasing the peak knee flexion moment (pKFM), which are the kinetic changes most frequently sought in patients with medial knee OA. Various approaches have been proposed to help the patients achieve this dual kinetic change, but more work is needed to determine how to implement gait retraining at best.

Change of Direction Biomechanics in a 180-Degree Pivot Turn and the Risk for Noncontact Knee Injuries in Youth Basketball and Floorball Players

Background: Studies investigating biomechanical risk factors for knee injuries in sport-specific tasks are needed. Purpose: To investigate the association between change of direction (COD) biomechanics in a 180-degree pivot turn and knee injury risk among youth team sport players. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 258 female and male basketball and floorball players (age range, 12-21 years) participated in the baseline COD test and follow-up. Complete data were obtained from 489 player-legs. Injuries, practice, and game exposure were registered for 12 months. The COD test consisted of a quick ball pass before and after a high-speed 180-degree pivot turn on the force plates. The following variables were analyzed: peak vertical ground-reaction force (N/kg); peak trunk lateral flexion angle (degree); peak knee flexion angle (degree); peak knee valgus angle (degree); peak knee flexion moment (N·m/kg); peak knee abduction moment (N·m/kg); and peak knee internal and external rotation moments (N·m/kg). Legs were analyzed separately and the mean of 3 trials was used in the analysis. Main outcome measure was a new acute noncontact knee injury. Results: A total of 18 new noncontact knee injuries were registered (0.3 injuries/1000 hours of exposure). Female players sustained 14 knee injuries and male players 4. A higher rate of knee injuries was observed in female players compared with male players (incidence rate ratio, 6.2; 95% CI, 2.1-21.7). Of all knee injuries, 8 were anterior cruciate ligament (ACL) injuries, all in female players. Female players displayed significantly larger peak knee valgus angles compared with male players (mean for female and male players, respectively: 13.9°± 9.4° and 2.0°± 8.5°). No significant associations between biomechanical variables and knee injury risk were found. Conclusion: Female players were at increased risk of knee and ACL injury compared with male players. Female players performed the 180-degree pivot turn with significantly larger knee valgus compared with male players. However, none of the investigated variables was associated with knee injury risk in youth basketball and floorball players.

Knee cartilage T2 relaxation times 3 months after ACL reconstruction are associated with knee gait variables linked to knee osteoarthritis.

Osteoarthritis development after ACL reconstruction (ACLR) is not well understood. Investigators have examined associations between knee biomechanical alterations and quantitative MRI (qMRI) variables, reflective of cartilage health, 12-60 months following ACLR; however, none have done so early after surgery. As part of an exploratory study, 45 individuals (age, 23 ± 7 years) underwent motion analysis during walking and qMRI 3 months after ACLR. For each limb, peak knee adduction moment (pKAM) and peak knee flexion moment (pKFM) were determined using inverse dynamics and peak medial compartment forcewas calculated using a neuromusculoskeletal model. T2 relaxation times in the medial compartment and linear regressions were used to determine the associations between gait variables and deep and superficial cartilage T2 relaxation times in six regions. pKAM was positively associated with deep layer T2 relaxation times within the femoral central and posterior regions when examined in the involved limb and from an interlimb difference perspective (involved limb - uninvolved limb). After adjusting for age, the association between interlimb difference of pKAM and interlimb difference of deep layer T2 relaxation times in the tibial central region became significant (p = .043). Interlimb difference of pKFM was negatively associated with interlimb difference of deep layer T2 relaxation times within the femoral central and posterior regions. These associations suggest that degenerative pathways leading to osteoarthritis may be detectable as early as 3 months after reconstruction. Preventative therapeutic techniques may need to be employed early in the rehabilitation process to prevent cartilage degradation.

Kinematic Comparison between Medially Congruent and Posterior-Stabilized Third-Generation TKA Designs.

Background: This study compares knee kinematics in two groups of patients who have undergone primary total knee arthroplasty (TKA) using two different modern designs: medially congruent (MC) and posterior-stabilized (PS). The aim of the study is to demonstrate only minimal differences between the groups. Methods: Ten TKA patients (4 PS, 6 MC) with successful clinical outcomes were evaluated through 3D knee kinematics analysis performed using a multicamera optoelectronic system and a force platform. Extracted kinematic data included knee flexion angle at heel-strike (KFH), peak midstance knee flexion angle (MSKFA), maximum and minimum knee adduction angle (KAA), and knee rotational angle at heel-strike. Data were compared with a group of healthy controls. Results: There were no differences in preferred walking speed between MC and PS groups, but we found consistent differences in knee function. At heel-strike, the knee tended to be more flexed in the PS group compared to the MC group; the MSKFA tended to be higher in the PS group compared to the MC group. There was a significant fluctuation in KAA during the swing phase in the PS group compared to the MC group, PS patients showed a higher peak knee flexion moment compared to MC patients, and the PS group had significantly less peak internal rotation moments than the MC group. Conclusions: Modern, third-generation TKA designs failed to reproduce normal knee kinematics. MC knees tended to reproduce a more natural kinematic pattern at heel-strike and during axial rotation, while PS knees showed better kinematics during mid-flexion.

Larger hip external rotation motion is associated with larger knee abduction and internal rotation motions during a drop vertical jump

ABSTRACT Associations among hip motions, knee abduction and internal rotation motion during a drop vertical jump (DVJ), which increases the risk of anterior cruciate ligament injury, remain unclear. The purpose of this study was to examine associations among knee abduction, internal rotation and hip joint motions during a DVJ. Fifty-seven young female participants performed a DVJ from a 30-cm height. Hip and knee kinematics and kinetics were analysed using a three-dimensional motion analysis system and force plates. Multiple regression analysis showed that peak knee abduction angle was negatively associated with knee internal rotation and hip internal rotation excursions from initial contact (IC) to peak knee flexion, and positively associated with peak knee abduction moment (R2 = 0.465, P< 0.001). Peak knee internal rotation angle was negatively associated with the hip flexion excursion from IC to peak knee flexion and peak hip adduction moment (R2 = 0.194, P= 0.001). In addition, hip internal rotation excursion was negatively associated with knee abduction and internal rotation excursion from IC to 50 ms after IC. To avoid a large knee abduction and internal rotation motion during jump-landing training, it might be beneficial to provide landing instructions to avoid a large hip external rotation motion.

Side-hops challenge knee control in the frontal and transversal plane more than hops for distance or height among ACL-reconstructed individuals

ABSTRACT We compared knee landing mechanics with presumed relation to risk of anterior cruciate ligament (ACL) injury among three single-leg hop tests and between legs in individuals with unilateral ACL reconstruction. Thirty-four participants (>10 months’ post-surgery, 23 females) performed the standardised rebound side hop (SRSH), maximal hop for distance (OLHD) and maximal vertical hop (OLVH). We calculated the following knee outcomes from motion capture and force plate data: finite helical axis inclination angles (approximates knee robustness), frontal and transversal plane angles at initial contact, peak angles of abduction and internal rotation during landing, and peak external moments of flexion, abduction and internal rotation during landing. Repeated-measures MANOVA analysis (‘sex’ as covariate) confirmed that SRSH induced greater angles and moments, particularly in the frontal plane, compared to OLHD and OLVH. There was between-leg asymmetry for peak knee flexion moment for males during OLHD and OLVH, and for females during SRSH. Our results advocate the SRSH over OLHD and OLVH for assessment of knee landing control to screen for movement patterns potentially related to ACL injury risk. However, clear differences in both knee kinematics and kinetics between OLHD and SRSH motivate the use of both tests to evaluate different aspects of landing control.

Patients Walking Faster After Anterior Cruciate Ligament Reconstruction Have More Gait Asymmetry

BackgroundGait asymmetries after anterior cruciate ligament reconstruction (ACLR) may lead to radiographic knee osteoarthritis. Slower walking speeds have been associated with biomarkers suggesting cartilage breakdown. The relationship between walking speed and gait symmetry after ACLR is unknown.Hypothesis/PurposeTo determine the relationship between self-selected walking speeds and gait symmetry in athletes after primary, unilateral ACLR.Study DesignSecondary analysis of a clinical trial.MethodsAthletes 24±8 weeks after primary ACLR walked at self-selected speeds as kinematics, kinetics, and electromyography data were collected. An EMG-driven musculoskeletal model was used to calculate peak medial compartment contact force (pMCCF). Variables of interest were peak knee flexion moment (pKFM) and angle (pKFA), knee flexion and extension (KEE) excursions, peak knee adduction moment (pKAM), and pMCCF. Univariate correlations were run for walking speed and each variable in the ACLR knee, contralateral knee, and interlimb difference (ILD).ResultsWeak to moderate positive correlations were observed for walking speed and all variables of interest in the contralateral knee (Pearson’s r=.301-.505, p≤0.01). In the ACLR knee, weak positive correlations were observed for only pKFM (r=.280, p=0.02) and pKFA (r=.263, p=0.03). Weak negative correlations were found for ILDs in pKFM (r=-0.248, p=0.04), KEE (r=-.260, p=0.03), pKAM (r=-.323, p<0.01), and pMCCF (r=-.286, p=0.02).ConclusionThose who walk faster after ACLR have more asymmetries, which are associated with the development of early OA. This data suggests that interventions that solely increase walking speed may accentuate gait symmetry in athletes early after ACLR. Gait-specific, unilateral, neuromuscular interventions for the ACLR knee may be needed to target gait asymmetries after ACLR.Level of EvidenceIII

Differences in stride length and lower limb moments of recreational runners during over-ground running while barefoot, in minimalist and in maximalist running shoes

The aim of this study was to compare stride length, and peak knee and ankle moments during over-ground running performed barefoot, in minimalist and in maximalist shoes. Fifteen (10 male, 5 female) recreational endurance runners who habitually wore conventional-cushioned shoes participated. Stride length, as well as knee and ankle moments, were recorded during running on an indoor runway at a self-selected comfortable speed while barefoot, in minimalist and in maximalist shoes. Each condition was performed on a different day and the order of conditions was randomised and counterbalanced. Differences in stride length, and peak knee and ankle moments between conditions were examined with ANCOVA with speed as the covariate. After adjusting for speed, there was a significant increase in stride length from barefoot (1.85 ± 0.01 m) to minimalist (1.91 ± 0.01 m) to maximalist shoes (1.95 ± 0.01 m). Peak knee flexion moment also increased significantly from barefoot (2.51 ± 0.06 Nm⋅kg−1) to minimalist (2.67 ± 0.06 Nm⋅kg−1) to maximalist shoes (2.81 ± 0.06 Nm⋅kg−1). Results then showed peak dorsiflexion moment was lower in the maximalist condition (2.34 ± 0.04 Nm⋅kg−1) than both the barefoot (2.57 ± 0.04 Nm⋅kg−1) and minimalist condition (2.66 ± 0.03 Nm⋅kg−1). Results suggest that stride length and peak knee flexion moment increase from barefoot to minimalist to maximalist shoes, and ankle moment significantly changes as a function of footwear. This indicates that footwear can influence self-selected stride length and peak lower limb loads that are a risk factor for running-related knee injury.

Impact of parity on biomechanical risk factors for knee OA initiation

BackgroundWomen are twice as likely as men to develop knee osteoarthritis (OA), and with it experience greater losses of physical function and disability. A change in the mechanical environment of the joint is a key initiating factor for knee OA. Differences in morphology, joint injury risk, and hormonal shifts in mid-life are often considered factors which increase OA risk for women. Pregnancy, a time of significant hormonal, morphological, and biomechanical change, has received comparably less attention. If morphological and biomechanical changes persist postpartum, this could increase OA risk for parous (childbearing) women. Research questionAre lower limb gait mechanics different between healthy nulliparous (non-childbearing) and parous (childbearing) women? MethodsTwenty-eight self-reported not pregnant female participants (14 parous, 14 nulliparous) were recruited for the study. Nulliparous participants had never given birth to a child. Parous participants had given birth to at least one full-term infant (37–42 weeks) without complications between one to five years before data collection. Motion capture of participants’ preferred, fast, and set (1.4 m/s) walking speeds was conducted. Repeated measures ANOVA were performed to test for significant group differences in joint kinematics and kinetics. ResultsThere was a significant main effect of group indicating a larger knee flexion angle at toe off (p = 0.0002), smaller knee extension moment at heel strike (p = 0.0006), smaller first peak knee flexion moment (p = 0.040), and smaller peak hip adduction moment for the parous group compared to the nulliparous group (p = 0.003). Static Q-angle did not differ between groups. SignificanceAlteration in mechanics from the habitual loading pattern are thought to increase risk of OA. Smaller knee moments in post-partum women could alter the mechanical stimulus to cartilage, and should be investigated in conjunction with cartilage health measures to determine the link with OA initiation.

Non-amputated limb muscle coordination of unilateral transfemoral amputees

Unilateral transfemoral amputees rely heavily on non-amputated limb muscles to regulate the prosthetic gait. In this study, we compared the non-amputated limb muscle coordination of eight unilateral transfemoral amputees to eight able-bodied controls. Inverse dynamics approach was conducted via a musculoskeletal model to obtain lower limb joint moments and muscle forces. In addition to the muscle forces at the instants of peak joint moments and the maximum muscle forces, the peak joint moments of the lower limbs were also investigated. The results showed that there were significant differences of muscle forces between the non-amputated limbs and the controls at the instant of peak hip extension moment, although the peak hip extension moments themselves were not significantly different between the two groups. The non-amputated limbs had significantly smaller peak hip flexion moment and peak knee extension moment, with significant differences between the muscle forces of non-amputated limbs and controls at the two instants. There was no significant difference between the muscle forces of the non-amputated limbs and controls at the peak knee flexion moment instant, despite the fact that the non-amputated limbs had significantly higher peak knee flexion moments. In addition, the non-amputated limbs had significantly smaller maximum muscle forces than the controls. These results demonstrate that amputees modify their muscle coordination to adapt to the specific joint requirements of the prosthetic gait. Our findings suggest the possibility of non-amputated limb muscle atrophy due to the decrease in the peak muscle forces during walking.