The objective of this research is to investigate the long-term performance of rubber-modified asphalt mixture (RMA) on Tire-Derived Aggregate (TDA)-replaced saturated subgrade as a drainage material. In lab testing setup, the mixtures were subjected to a 5-day conditioning at 85°C to ensure complete long-term aging. A series of laboratory and field tests were conducted. The study found that the surface course rubber mix had the best-cracking resistance than the leveling course control mix and surface layer control mix. Additionally, the fracture energy of the surface layer rubber mix was 17.4–21.9 % higher than that of the surface layer control mix. After the long-term aging condition, all three types of hot mix asphalt (HMA) exhibited exceptional resistance to deformation. Rubber-modified asphalt improved fatigue properties and crack performance. In summary, implementing RMA in pavement construction improved the pavement's thermal cracking and fatigue properties and significantly reduced pavement noise. TDA has potential as a fill material in subgrade applications, and rubber-modified asphalt shows promising performance for asphalt pavement.