The study of soil erosion is significant to soil and water conservation and ecological construction planning. CA, a dynamic modeling method, has been widely used to simulate the future changes of soil erosion intensity. In this study, three slopes with different vegetation patterns (uniform distribution, aggregated distribution, and random distribution) and a bare slope in the Baojiagou watershed in the Pisha sandstone area were taken as the study objects. Based on the soil erosion intensity grade maps of slopes with different vegetation patterns under the three periods of rainfall, the soil erosion intensity grade maps of the four slopes were simulated by combining multi-criteria evaluation (MCE) and Markov chain (CA-Markov). Through tests, the Kappa coefficients of the simulated maps of uniform distribution, random distribution, aggregated distribution and a bare slope reached 80.15%, 75.41%, 75.92% and 76.48%, respectively. The results revealed that the soil erosion types on slopes with different vegetation patterns were transferred differently, and fewer erosion areas were generally transferred into highly eroded ones, with moderately and slightly eroded areas as the main transfer flows. After simulating the grade map of soil erosion intensity on slopes with different vegetation patterns, it was found that the slopes with uniform and random vegetation distribution primary displayed the transfer from highly eroded areas to less eroded ones, and the sedimentary area was enlarged, while the slope with aggregated vegetation distribution and the bare slope mainly presented the transfer from less eroded areas to highly eroded ones. The sedimentary area was diminished. Therefore, compared with the bare slope, the slopes with uniform and random vegetation distribution exerted a better inhibitory effect on the soil erosion degree of hydraulically eroded slopes, and the inhibitory effect of aggregated vegetation distribution-type slope was the weakest. The study results provide critical information for planning and implementing soil conservation measures in the study area.