Position In Patients Research Articles

Comparison of the effectiveness of awake-prone positioning and high-flow nasal oxygen in patients with COVID-19-related acute respiratory failure between different waves.

To compare the effectiveness of the awake-prone position on relevant clinical outcomes in patients with COVID-19-related acute respiratory failure requiring high-flow nasal oxygen between different waves in Argentina. This multicenter, prospective cohort study included adult patients with COVID-19-related acute respiratory failure requiring high-flow nasal oxygen. The main exposure position was the awake-prone position (≥ 6 hours/day) compared to the non-prone position. The primary outcome was endotracheal intubation, and the secondary outcome was in-hospital mortality. The inverse probability weighting-propensity score was used to adjust the conditional probability of treatment assignment. We then adjusted for contextual variables that varied over time and compared the effectiveness between the first and second waves. A total of 728 patients were included: 360 during the first wave and 368 during the second wave, of whom 195 (54%) and 227 (62%) remained awake-prone for a median (p25 - 75) of 12 (10 - 16) and 14 (8 - 17) hours/day, respectively (Awake-Prone Position Group). The ORs (95%CIs) for endotracheal intubation in the Awake-Prone Position Group were 0.25 (0.13 - 0.46) and 0.19 (0.09 - 0.31) for the first and second waves, respectively (p = 0.41 for comparison between waves). The ORs for in-hospital mortality in the awake-prone position were 0.35 (0.17 - 0.65) and 0.22 (0.12 - 0.43), respectively (p = 0.44 for comparison between waves). The awake-prone position was associated with a reduction in the risk of endotracheal intubation and in-hospital mortality. These effects were independent of the context in which the intervention was applied, and no differences were observed between the different waves.

Impact of acetabular roof's angle on precision of cup center of rotation reproduction and placement in total hip arthroplasty.

Total hip arthroplasty (THA) is nowadays considered as the most effective treatment option for end-stage hip osteoarthritis (OA) and one of the most successful orthopedic procedures. Precise reproduction of the center of rotation (COR) is among the most important aspects of recreating native hip biomechanics after THA as it is strictly related to muscle tension and force distribution within the hip joint. Both vertical and horizontal shift in cup positioning and COR restoration are commonly observed radiological signs corresponding with lesser functional outcome. The aim of this study was to assess whether the superior border of the native acetabulum morphology has an impact on cup positioning and COR restoration in patients undergoing THA as treatment of primary OA of the hip. A cohort of 150 consecutive patients with diagnosis of end-stage primary hip OA who underwent THA via an anterolateral approach with the same implant in 2021 was analyzed retrospectively. Standard standing pelvic X-rays were performed pre- and postoperatively and appropriate measurements were taken. Several radiological parameters on obtained X-rays were assessed. Statistical analysis of all the measurements was performed. There was a statistically significant positive weak correlation between cup offset and acetabular roof angle (rs = 0.25, p = 0.002). There were statistically insignificant positive correlations between acetabular roof angle and COR restoration (rs = 0.14, p = 0.097), acetabular roof angle and total offset (rs = 0.087, p = 0.29) and a negative correlation between acetabular roof angle and femoral offset (rs = 0.071, p = 0.39). The present study revealed that preoperative acetabular roof angle influences the positioning of the prosthetic cup in the transverse axis. There also seems to be a correlation between the acetabular roof angle and COR restoration, but its significance needs further evaluation. Surgeons could use this knowledge to preoperatively assess the risk of cup malposition and adjust their technique during the THA procedure with probable improvement of hip function.

Early Outcomes of Pulmonary Valve Replacement With the Edwards Inspiris Resilia Pericardial Bioprosthesis.

Controversy regarding the optimal pulmonary valve substitute remains, with no approved surgical valve for pulmonary valve replacement (PVR). Furthermore, unfavorable anatomy often precludes transcatheter PVR in patients with congenital heart disease. We therefore sought to evaluate the feasibility of the Edwards Inspiris pericardial aortic bioprosthesis in the pulmonary position in pediatric and adult patients requiring PVR. Data from consecutive patients who underwent PVR from February 2019 to February 2021 at our institution were retrospectively reviewed. Postoperative adverse events included paravalvular or transvalvular leak, endocarditis, explant, thromboembolism, valve thrombosis, valve-related bleeding, hemolysis, and structural valve degeneration. Progression of valve gradients was assessed from discharge to 30 days and one year. Of 24 patients with median age of 26 years (interquartile range [IQR]: 17-33; range: 4-60 years), 22 (91.7%) patients had previously undergone tetralogy of Fallot repair and 2 (8.3%) patients had undergone double-outlet right ventricle repair in the neonatal period or infancy. All patients had at least mild right ventricular (RV) dilatation (median RV end-diastolic volume index 161.4, IQR: 152.3-183.5 mL/m2) and at least moderate pulmonary insufficiency (95.8%) or stenosis (8.3%). Median cardiopulmonary bypass and cross-clamp times were 71 (IQR: 63-101) min and 66 (IQR: 60-114) min, respectively. At a median postoperative follow-up of 2.5 years (IQR: 1.4-2.6; range: 1.0-3.0 years), there were no mortalities, valve-related reoperations, or adverse events. Postoperative valve gradients and the severity of pulmonary regurgitation did not change significantly over time. At short-term follow-up, the bioprosthesis in this study demonstrated excellent safety and effectiveness for PVR. Further studies with longer follow-up are warranted.

A special face mask with integrated angle meter to optimize the head position for bag-valve-mask ventilation—a prospective simulated proof-of-concept study

The supine position in unconscious patients resulted in the tongue falling back because of the loss of muscle tension which obstructed the upper airway. The head reclination opened the airway, however unexperienced rescuers faced difficulties in performing bag-valve-mask ventilation as it was hard to detect the optimal head position for opening the airway. The bag-valve-mask ventilation could be optimized if it indicated an optimized head angle to the rescuer. A digital sensor was attached to the face mask for measuring the degree of head reclination. Moreover, the face mask was equipped with an airway trainer and sealed via adhesive tape. The airway trainer was connected to a test lung and ventilated through pressure-controlled standard anesthesia machine (Pmax = 10 mbar, Positive End Expiratory Pressure (PEEP) = 0 mbar, f = 12/min). The head of airway manikin was tilted to 42 degrees starting from neutral position with a gradient of 2 degrees. The primary endpoint was the correlation of preset angles and digitally measured head position angles via the mask. In addition, the tidal and minute volumes were evaluated based on the head reclination. The preset and the digitally measured head position angles depicted correlation (R2 = 0.9895855684; p < 0.001). The tidal volume was 150 mL in head position angle of <10 degrees, 200 mL at 18 degrees, 450 mL at 25 degrees, and it levelled with about 500 mL at 30 degrees. In conclusion, digital head position angle was measured to detect the correct head position. A signal in the face mask could indicate the optimized head position to the first respondents or inexperienced rescuers in emergency ventilation.

Analysis of viral aerosol distribution characteristics in typical body positions of patients under local exhaust air

In this paper, CFD numerical simulation and experiment were used to simulate the diffusion process of human exhaled aerosol particles, and the influence of human lying down, sitting and standing posture on the diffusion of aerosol particles under local exhaust air conditions was studied. The results show that different body positions have significant effects on local exhaust air effect. Only 13.2% of the aerosol particles could be removed by local exhaust air in the lying state. The exclusion rate in sitting posture was 25.4%; The exclusion rate for standing posture was 20.6%. Local exhaust air alone is not enough to prevent infection. It is recommended to adopt the combination of mixed ventilation and local exhaust air, which may have a better effect on preventing cross infection, indoor particulate matter transmission and controlling pollution.

Creation of a microsurgical neuroanatomy laboratory and virtual operating room: a preliminary study.

A comprehensive understanding of microsurgical neuroanatomy, familiarity with the operating room environment, patient positioning in relation to the surgery, and knowledge of surgical approaches is crucial in neurosurgical education. However, challenges such as limited patient exposure, heightened patient safety concerns, a decreased availability of surgical cases during training, and difficulties in accessing cadavers and laboratories have adversely impacted this education. Three-dimensional (3D) models and augmented reality (AR) applications can be utilized to depict the cortical and white matter anatomy of the brain, create virtual models of patient surgical positions, and simulate the operating room and neuroanatomy laboratory environment. Herein, the authors, who used a single application, aimed to demonstrate the creation of 3D models of anatomical cadaver dissections, surgical approaches, patient surgical positions, and operating room and laboratory designs as alternative educational materials for neurosurgical training. A 3D modeling application (Scaniverse) was employed to generate 3D models of cadaveric brain specimens and surgical approaches using photogrammetry. It was also used to create virtual representations of the operating room and laboratory environment, as well as the surgical positions of patients, by utilizing light detection and ranging (LiDAR) sensor technology for accurate spatial mapping. These virtual models were then presented in AR for educational purposes. Virtual representations in three dimensions were created to depict cadaver specimens, surgical approaches, patient surgical positions, and the operating room and laboratory environment. These models offer the flexibility of rotation and movement in various planes for improved visualization and understanding. The operating room and laboratory environment were rendered in three dimensions to create a simulation that could be navigated using AR and mixed reality technology. Realistic cadaveric models with intricate details were showcased on internet-based platforms and AR platforms for enhanced visualization and learning. The utilization of this cost-effective, straightforward, and readily available approach to generate 3D models has the potential to enhance neuroanatomical and neurosurgical education. These digital models can be easily stored and shared via the internet, making them accessible to neurosurgeons worldwide for educational purposes.

Effects of sagittal split Ramus osteotomy on condylar position and Ramal orientation in patients with mandibular asymmetry.

The purpose of this study is to assess the impact of Sagittal Split Ramus Osteotomy (SSRO) on the alignment of the condyle and orientation of the Ramal segment following surgery in patients operated for the correction of mandibular asymmetry. A total of 27 patients who underwent SSRO were enrolled in this study, and study groups were defined as asymmetric (study group) and symmetric (control group) using linear measurements from the dental midline based on a three-dimensional coordinate system. Differences on preoperative and postoperative values of anterior (AJS), posterior (PJS) and superior joint spaces (SJS), condylar axial angle (CAA), Sagittal Ramal Angle (SRA), and Coronal Ramal Angles (CRA) of study and control groups were measured and compared. The data was analyzed using the "Wilcoxon signed-ranks test" to identify differences between groups. Differences between preoperative and postoperative values of CRA and SRA of the contralateral group showed statistically significant results with p-values of 0.007 and 0.005, respectively. A statistically significant change in CAA angle was found in the control and deviation groups (p = 0.018 and p = 0.010, respectively). SSRO has inevitable effects on the condylar and ramal orientation. Individuals with asymmetry require particular attention throughout the planning process and beyond. Conjunctive modalities and modifications should be considered and utilized when necessary. Future studies with larger sample sizes, homogenous follow-up periods, and more comprehensive clinical data are needed to substantiate understanding of the response of the condylar segment. Orthognathic surgeries inevitably alter the alignment and harmony of temporomandibular structures and may result in change of AJS, PJS, SJS, CAA, SRA, and LRA, which may change the biomechanics of joint and lead to several complications like temporomandibular disorders. Especially in cases with midline asymmetry needs special consideration from planning till the end of the treatment to achieve best results. In severe cases, conjunctive modalities and modifications and other alternatives such as inverted-L osteotomies should be considered.

Administration of combined spinal epidural anesthesia with ultrasound-assisted positioning in obese patients undergoing open hysterectomy: A randomized controlled trial

Background: Administration of combined spinal epidural anesthesia (CSEA) with traditional landmark-guided positioning can be challenging in patients with high body mass index (BMI). The popularization of ultrasound technology may effectively solve these problems. However, reports on the administration of CSEA ultrasound-assisted positioning in obese populations are relatively limited and have made inconsistent conclusions. We aimed to investigate the ability of ultrasound-assisted positioning to improve the success rate of CSEA in obese patients. Methods: Overall, 118 adult women with a BMI ≥ 30 kg/m2 who scheduled to undergo open hysterectomy and received CSEA were recruited. Finally, 108 patients were enrolled and randomly assigned to 2 groups: the ultrasound-assisted positioning group (group A) and traditional landmark-guided positioning group (group B). Ultrasound-assisted or landmark-guided positioning was employed to locate the puncture interspace before anesthesia. The primary outcomes were the success rate of first attempt and number of attempts. The secondary outcomes were the patient positioning accuracy, positioning time, CSEA operation time, patient-satisfaction scores, anesthesia characteristics, and complications of CSEA. Results: The success rate of patient first puncture attempt in group A was significantly higher than that in group B (78.4% vs 52.9%, P = .007). The total number of punctures was lower in group A than that in groups B (average rank 44.54 vs 58.46, P = .005). Using ultrasound positioning as the gold standard, the accuracy of landmark-guided location was only 67%. Positioning time in croup A was longer in group A than that in group B (P = .004), while CSEA operation time spent in Group A was less than that in Group B (P < .001). Patient satisfaction score in group A was significantly higher than that in group B (P = .002). The successful puncture interspace in group A were more likely at L3-4 than that in group B (P = .02). Conclusion: The success rate of first puncture attempt and positioning accuracy in CSEA with ultrasound-assisted is significantly higher than those based on landmark-guided location in obese patients.

Accuracy and stability of the condyle position after orthognathic surgery: A retrospective study

The purpose of this study was to evaluate the accuracy and stability of condylar positioning in patients treated with bimaxillary procedures compared with patients treated with maxillary procedures alone.All patients had undergone treatment at Odense University Hospital and were treated with inferior maxillary procedures. The primary outcome was changes in condyle position and the primary predictor variable was time: pre-operative (T0) measurements to 1-week post-operative (T1) and 1-year post-operative (T2) measurements. Condyle movement was measured using dual voxel-based alignment.Sixteen patients were included. Seven patients underwent solitary maxillary procedure and 9 patients bimaxillary procedure. Bimaxillary procedures overall showed a condyle positional change in pitch from T0 to T1 and T1 to T2 compared to maxillary procedures alone. Condylar translation was stable despite large differences in positioning. Compared to solitary maxillary procedures, bimaxillary procedures showed a statistically significant anterocranial rotation at 1-week follow-up movement (3.95° vs. −0.95°; SD 3,74 vs 1,05; P value = 0.000) and an additional statistically significant anterocranial movement at 1 year after surgery (4.89° vs 0.60°; SD 3,82 vs 0,92; P value = 0.000).In conclusion a need for greater anterocranial stability of the sagittal split osteotomy than that provided by 3 bicortically fixated screws alone might be indicated.

Long-Term Survival Benefits of Porcine versus Pericardial Bioprostheses in Elderly Patients Undergoing Isolated Aortic Valve Replacement: A 32-Year Study.

The elderly population is growing at an unprecedented rate. Aortic valve disease increases with age. Bioprostheses are the valves of choice for older patients; however, the optimal tissue valve remains undetermined. The purpose of this investigation was to perform a life-of-patient survival comparison of the prototypical porcine and pericardial prostheses in elderly patients. The study population (N = 1480) consisted of patients 65 years of age and older who underwent isolated aortic valve replacement from 1990 through 2005 with a Carpentier-Edwards Porcine (n = 650) or Pericardial (n = 830) bioprosthesis. Propensity score-matched groups were created. Valve selection was not associated with operative mortality. Survival estimates at 10 years were better for Pericardial (41.8%; 95% CI: 37.9 to 45.7) than Porcine (32.6%; 95% CI: 28.8 to 36.3); and 5.2% (95% CI: 3.2 to 7.1) versus 2.0%; (95% CI: 0.8 to 3.2) at 20 years (p < 0.001). E-value analysis found minimal influence of unknown study confounders. Factors associated with long-term mortality were porcine valve (p < 0.001), age (p < 0.001), diabetes mellitus (p < 0.001), preop renal insufficiency (p < 0.001), peripheral artery disease (p = 0.011), congestive heart failure (p = 0.003), New York Heart Association Class III or IV (p = 0.004), surgical history-reoperation (p = 0.012), transient ischemic attack (p = 0.009), prolonged ventilation (p = 0.010), postop renal insufficiency (p < 0.001), and atrial fibrillation (p = 0.009). The indexed Effective Orifice Area (EOAi) was assessed and did not influence observed long-term survival differences. This unusual lifetime study provided substantial evidence for the superiority of the pericardial over the porcine bioprosthesis in the aortic position in elderly patients. It demonstrated enhanced long-term survival benefits for elderly patients without any increase in perioperative mortality. It is intended to inform future investigation into aortic valve design.

Prone position in patients admitted to the Intensive Care Unit with a diagnosis of COVID-19

Objetivo: caracterizar la terapia de posición prono y sus principales complicaciones en pacientes que ingresan a una Unidad de Cuidado Intensivo con diagnóstico de COVID-19. Metodología: estudio observacional de corte transversal. A partir de registros clínicos de 386 pacientes con diagnóstico de COVID-19 ingresados a una Unidad de Cuidado Intensivo (UCI) de tercer nivel de complejidad en el periodo marzo 2020-marzo 2021. Se analizaron características clínicas al ingreso a UCI, variables relacionadas con la pronación, complicaciones en pacientes pronados. Investigación aprobada por el comité de ética de la universidad CES. Resultados: La mayoría de los pacientes ingresados a UCI por COVID-19 eran hombres, con edad promedio de 61 años y un peso promedio de 77 kg. Casi la mitad ingresaron con la presión alta. El valor promedio de la frecuencia respiratoria fue de 24 por minuto y de oximetría de 92.8%. El 58% recibieron terapia de posición prono. El número máximo de ciclos fue de 14 con una duración promedio de 21 horas. El 60.6% presentó una o varias complicaciones, posterior a la pronación. Conclusión: La pronación es una intervención que mejora los índices de oxigenación en los pacientes con falla respiratoria por COVID-19 o de otra etiología. Pese a sus beneficios, no está exenta de riesgos, entre los que se destaca la alta prevalencia de lesiones en piel. Esto puede estar influenciado por el contexto de pandemia que conlleva a una mayor carga que recae sobre los sistemas de salud y permea la prestación de servicios de salud.

Improved oxygenation in prone positioning of mechanically ventilated patients with COVID-19 acute respiratory distress syndrome is associated with decreased pulmonary shunt fraction: a prospective multicenter study

BackgroundProne position is used in acute respiratory distress syndrome and in coronavirus disease 2019 (Covid-19) acute respiratory distress syndrome (ARDS). However, physiological mechanisms remain unclear. The aim of this study was to determine whether improved oxygenation was related to pulmonary shunt fraction (Q’s/Q’t), alveolar dead space (Vd/Vtalv) and ventilation/perfusion mismatch (V’A/Q’).MethodsThis was an international, prospective, observational, multicenter, cohort study, including six intensive care units in Sweden and Poland and 71 mechanically ventilated adult patients.ResultsProne position increased PaO2:FiO2 after 30 min, by 78% (83–148 mm Hg). The effect persisted 120 min after return to supine (p < 0.001). The oxygenation index decreased 30 min after prone positioning by 43% (21–12 units). Q’s/Q’t decreased already after 30 min in the prone position by 17% (0.41–0.34). The effect persisted 120 min after return to supine (p < 0.005). Q’s/Q’t and PaO2:FiO2 were correlated both in prone (Beta -137) (p < 0.001) and in the supine position (Beta -270) (p < 0.001). V’A/Q’ was unaffected and did not correlate to PaO2:FiO2 (p = 0.8). Vd/Vtalv increased at 120 min by 11% (0.55–0.61) (p < 0.05) and did not correlate to PaO2:FiO2 (p = 0.3). The ventilatory ratio increased after 30 min in the prone position by 58% (1.9–3.0) (p < 0.001). PaO2:FiO2 at baseline predicted PaO2:FiO2 at 30 min after proning (Beta 1.3) (p < 0.001).ConclusionsImproved oxygenation by prone positioning in COVID-19 ARDS patients was primarily associated with a decrease in pulmonary shunt fraction. Dead space remained high and the global V’A/Q’ measure could not explain the differences in gas exchange.

Enteral nutrition practice in the prone position in patients with coronavirus disease 2019: An international one-day point prevalence analysis

Enteral nutrition (EN) in the prone position for severe respiratory failure is considered possible with care. However, the extent to which it is feasible, especially its association with the length of intensive care unit (ICU) stay, is unclear. Therefore, we investigated the relationship between the duration of prone position therapy and adequacy of EN delivery and explored factors associated with this relationship in an observational study of critically ill patients with coronavirus disease 2019 (COVID-19) who were actively treated in the prone position. This study was a secondary analysis of a worldwide one-day prevalence study in the COVID-19 era. We investigated the care and nutritional therapy provided to critically ill patients with COVID-19 admitted to ICU, along with ICU-related information. We targeted patients who received only tube feeding and analyzed the relationship between the duration of prone position, length of ICU stays, and nutrition delivery via EN. In addition, a multivariate analysis was performed to examine factors affecting the achievement of EN delivery of 20kcal/kg/day or more in patients who were placed in the prone position for at least 6h. A total of 399 patients who received only EN, excluding parenteral nutrition and oral intake, were included, of whom 58% received EN energy delivery of ≥20kcal/kg/day; this rate increased with the length of ICU stay, regardless of the duration of prone position. In a multivariate analysis of 121 patients who were in the prone position for at least 6h, the presence of dedicated dietitians in the ICU (OR=6.91, 95% CI=1.98 to 24.1, p<0.01) was associated with a higher energy delivery. Conversely, the use of muscle relaxants (OR=0.32, 95% CI=0.11 to 0.98, p=0.04) and presence of nutrition protocols (OR=0.24, 95% CI=0.07 to 0.77, p=0.02) was associated with a lower energy delivery. Patients with COVID-19 received adequate nutrition by EN even during prone position. Target EN delivery would be achieved with the introduction of prone position.

Advantages of using ultrasound diagnostic methods in the practice of an anesthesiologist on the example of neurosurgical interventions in the sitting position in pediatric patients with brain tumors

The purpose of the publication is to improve the results of treatment of children with brain tumors with the help of high-quality monitoring during neurosurgical operations with the localization of pathological formations that require the patient to be in a sitting position; encourage anesthesiologists to acquire the necessary additional skills in ultrasound diagnostics.For the description of the clinical case, the authors obtained the written informed consent of patients No. 1 and No. 2 to use the materials of his medical history in the article, in accordance with the Ethical Standards of Legal Regulation of Relations.Two clinical cases of anesthesiological management of patients with neurooncopathology (neoplasm of the left cerebellar peduncle with prolapse in the IV ventricle area and volume formation of the pineal area) operated on in the sitting position with standard monitoring (pulse oximetry, electrocardiography, non-invasive measurement of arterial blood pressure, thermometry, capnography, other gas analyzer), supplemented by invasive measurement of central venous pressure, bispectral index (BIS) monitoring, neurophysiological parameters, transesophageal echocardiography (the sensor is selected according to the patient's age). Clinical, laboratory, biochemical, ultrasound, endoscopic, x-ray methods, computer and magnetic resonance imaging were used to establish a diagnosis, determine the nature of complications, choose access and methods of surgical intervention, evaluate the effectiveness of treatment and diagnostics.The sitting position during surgery is the neurosurgeon’s choice because this position improves access to the tumor, reduces the volume of blood loss and intracranial pressure, but increases the risk of intraoperative complications, in particular, air embolism, which was diagnosed by echocardiography. The National Children’s Specialized Hospital «Okhmatdyt» has the necessary equipment (in particular, a neurosurgical chair) for performing neurosurgical interventions in a sitting position. During the surgical intervention, in one clinical case, an air embolism of the 2nd degree according to the Tubingen scale was recorded, without other changes according to the measurement of arterial and central venous pressure, BIS and neurophysiological monitoring. In the second case, an air embolism of the 1st degree was recorded. Both patients were extubated on the operating table at the end of the operation and were observed during the day in the intensive care unit. The early postoperative period was uneventful. According to the control magnetic resonance imaging, postoperative moderate pneumocephalus developed, which did not require repeated surgical intervention. During the operation, monitoring was carried out using pulse oximetry and electrocardiography.This article does not aim to review the specific indications for transesophageal echocardiography or a comprehensive description of all complications that can be visualized using this method during operative neurosurgical interventions. This article presents two cases that demonstrate the success of using this method by an anesthesiologist. According to the authors, it is advisable to introduce the use of ultrasound methods into the daily practice of an anesthesiologist.High-quality monitoring is important for early detection and prevention of complications. Thanks to the professionalism and expanded arsenal of practical skills of the team of doctors of the NCSH «Okhmatdit», in particular, anesthesiologists, in both cases, high-tech medical care was provided with a good prognosis for the future life of these patients.

Variations in pelvic tilt during day-to-day activities after total hip arthroplasty measured with an ultrasound system

IntroductionThe pelvis plays a major role in the orientation of total hip arthroplasty (THA) implants and consequently, on the postoperative stability of the new hip joint. The relationship between the spine and pelvis affects the functional orientation of the acetabular cup, although this relationship differs between individuals and the positions encountered in everyday life. We believe this should be factored in when planning the THA procedure. This led us to conduct an in vivo ultrasound study to document the values of pelvic tilt in standing, sitting and lying positions in patients who have advanced hip osteoarthritis, before and after they undergo THA. HypothesisThe pelvic tilt when standing, sitting and lying supine does not change significantly after THA. Materials and methodsThe pelvic tilt, defined as the angle between the anterior pelvic plane and a vertical line was measured using an ultrasound device in 30 patients before the THA procedure and again 6 months later in standing, sitting and lying positions. The measurements were done during an office visit with the patient on an examination table for the lying position, on a chair for the sitting position and with the heels and occiput against the wall for the standing position. ResultsThe preoperative and 6-month postoperative pelvic tilt were –5.6̊±10.4̊ [–30.6̊; 11.7̊] and –5.8̊±7.9̊ [–20.6̊; 10.4̊] (p=0.4129) when standing, –44.5̊±6.10 [–53.8̊; –23.9̊] and –43.5̊±6.9̊ [–54.4̊; –17.3̊] (p=0.5760) when sitting, –88.3̊±5.1̊ [–99.3̊; –78.7̊] and –87.9̊±5.9̊ [–97.6̊; –72.4̊] (p=0.6106) when lying supine, respectively. There was no significant difference in the pelvic tilt before and 6 months after THA procedure. Variations of±5̊; ±5–10̊; ±10–15̊ and 15–20̊ were found in 72% (18); 20% (5); 4% (1) and 4% (1) of patients when lying supine, 56% (14); 36% (9); 8% (2); 0% (0) of patients when standing and 76% (19); 24% (6); 0% (0); 0% (0) when sitting. The mean variation for each patient between the preoperative and 6 months postoperative measurement was 4.8±3.4̊ [0.8̊; 10.4̊] (p=0.4129), 3.5±2.3̊ [0.2̊; 9.1̊] (p=0.5760), and 4.6̊±3.2̊ [1.2̊; 15.4̊] (p=0.6106) for the standing, sitting and lying positions respectively. ConclusionThe pelvic tilt does not significantly change 6 months after THA. Taking into account the various positions used in everyday life may help to optimize the implant position. We have described the use of an affordable, accurate and non-irradiating device that provides fast and easy measurements of pelvic tilt in various positions. Level of evidenceIV.

Prone Positioning in Patients With COVID-19 and Non-COVID-19 Acute Respiratory Distress Syndrome.

Patients critically ill with COVID-19 develop acute respiratory distress syndrome (ARDS) and may undergo prone positioning. To compare the effects of prone positioning on oxygenation, intensive care unit length of stay, and intubation days in patients with COVID-19 ARDS and patients with non-COVID-19 ARDS. A convenience sample of intubated patients with COVID-19 and moderate to severe ARDS (per Berlin criteria) was compared with historical data from a retrospective, descriptive medical record review of patients with non-COVID-19 ARDS. The historical comparison group was age and sex matched. Differences in Po2 to fraction of inspired oxygen ratios between the COVID-19 ARDS group (n = 41) and the non-COVID-19 ARDS group (n = 6) during the first 7 days of prone positioning were significant at the end of prone positioning on day 1 (P = .01), day 3 (P = .04), and day 4 (P = .04). Wilcoxon signed-rank tests showed that prone positioning had a positive impact on Po2 to fraction of inspired oxygen ratios from day 1 through day 6 in the COVID-19 ARDS group and on day 2 in the non-COVID-19 ARDS group. This retrospective review found greater improvement in oxygenation in the COVID-19 ARDS group than in the non-COVID-19 ARDS group. This finding may be attributed to the assertive prone positioning protocol during the pandemic and teams whose skills and training were likely enhanced by the pandemic demand. Prone positioning did not affect intensive care unit length of stay or intubation days in either group.

Importance of timing and training to implement awake prone positioning in patients with COVID-19: a single-center prospective observational study.

Awake prone positioning (APP) is broadly implemented in patients with severe acute respiratory syndrome coronavirus 2 related disease [coronavirus disease 2019 (COVID-19)] admitted to hospital with severe respiratory distress syndrome. This prospective observational study aimed to explore the factors influencing the implementation of APP in patients with acute respiratory failure due to COVID-19. Patients with COVID-19, all hospitalized with positive X-ray findings and oxygen supplementation requirement, in the Respiratory Step-Down Unit of the Peking University Third Hospital between January 6th, 2023, and January 20th, 2023, were included in this study. Data regarding basic information, activities of daily living (ADLs) scores, oxygen therapy, vital signs, and duration of APP were collected to investigate the factors influencing prone positioning. Among the 134 patients included, 55.2% showed an improvement in oxygen saturation 1 hour after APP. Logistic regression revealed that the pre-APP heart rate (HR) [odds ratio (OR) =1.032; P=0.046] and peripheral oxygen saturation (SpO2) (OR =0.720; P<0.001) were the associated factors of the improvement in SpO2 after treatment. Multiple linear regression revealed that the ADL scores and pre-APP respiratory rate (RR) were the associated factors of the duration of prone positioning (P<0.01). The APP technical steering group effectively improved duration of APP. Patients with low SpO2 and increased HR before treatment showed greater improvement in oxygen saturation. Patients with lower tolerance to ADL but lower RRs were those to demonstrate a longer duration of prone positioning. This is pointing towards establishing the most favorable time window for APP during the course of COVID-19: after the ADLs have already decreased, but before significant tachypnea has appeared.

Compliance of Prone Positioning in Non-Intubated COVID-19 Patients.

Compliance of Prone Positioning in Non-Intubated COVID-19 Patients.

Effect of Awake Prone Position in Covid-19 Patients with MildModerate Symptoms to Reduce the Risk of Developing into Severe Cases : A Systematic Review

Introduction: The prone position is a method to increase ventilation in the breathing process. This study will carry out a systematic review of previous journals that discuss the impact of the awake prone position on corona virus disease-19 patients which can reduce the risk of developing into a severe case. Methods: A literature search was conducted in the last 5 years of research selected from several indexed electronic databases (Scopus, Science Direct, PubMed, Web of Science ). A total of 27 8 articles were obtained, and after being selected, 1 2 were found to be selected based on criteria and were a randomized control trial, Cohort Retrospective Study , case control. Results: 8 articles explaining that the awake prone position is effective in improving hypoxic conditions marked by increased oxygen saturation in the blood of corona virus disease-19 patients with mild-moderate symptoms. Conclusion: The awake prone position exercise is still the main choice for therapy in corona virus disease-19 patients with mild-moderate acute respiratory distress syndrome. Because it causes an increase in oxygenation and mechanical respiratory function in patients thereby reducing the risk of becoming a severe case.

A COMPARATIVE STUDY TO ASSESS EFFECTS OF PNEUMOPERITONEUM AND TRENDELENBURG POSITION ON HEMODYNAMICS AND VENTILATORY MECHANICS DURING TOTAL LAPAROSCOPIC HYSTERECTOMY IN OBESE AND NON-OBESE PATIENTS

Background:Hysterectomy is a common gynaecological surgical procedure, with Laparoscopic hysterectomy (LH) emerging as a favorable approach due to its benefits such as shorter recovery periods and reduced complications. However, the creation of pneumoperitoneum and the Trendelenburg position required for total laparoscopic hysterectomy (TLH) can induce significant hemodynamic and ventilatory changes. Methodology: Our study included 60 patients who were categorized into two groups of 30 each based on their BMI: non-obese (BMI &lt; 30) and obese (BMI ≥ 30). All patients underwent routine pre-anaesthesia check-up followed by general anaesthesia. Diastolic blood pressure (DBP), systolic blood pressure (SBP), peripheral oxygen saturation (SpO2), heart rate (HR), mean arterial pressure (MAP), plateau pressure (PPLAT), peak pressure (PPEAK),and driving pressure (PDRIVING), end-tidal carbon dioxide (EtCO2) as well as static (CST) and dynamic (CDYN) lung compliance were measured at different time intervals including baseline, following induction of anaesthesia, insufflation, changing to Trendelenburg position, desufflation and after extubation. Results:The heart rate decreased on induction of anesthesia in both the groups and remained lower throughout the procedure but was statistically non-significant (p&gt;0.05). There was a rise in SBP, DBP, and MAP on insufflation and further with head-down positioning in both obese and non-obese patients, however, was statistically non-significant (p&gt;0.05). The PPEAK, PPLAT, and PDRIVING were increased on induction, following the creation of pneumoperitoneum as well as Trendelenburg position (p&lt;0.05). The values were higher in obese as compared to the non-obese. The static and dynamic compliance were lower at all time intervals in obese patients when compared to the non-obese group. Conclusion: Obese patients exhibit higher plateau pressure, peak inspiratory pressure, and driving pressure values, indicating increased airway resistance and potential ventilation challenges during surgery. Additionally, the reduced static and dynamic lung compliance values in obese patients suggest decreased lung elasticity and difficult ventilation.