Physical Activity In Patients Research Articles

Management of Marfan Syndrome, with a Specific Focus on the Significance of Physical Activity in this Patient Population

Introduction: Marfan syndrome is an autosomal dominant disorder of connective tissue. Timely diagnosis and effective therapy are essential for individuals with Marfan syndrome, as they are susceptible to severe cardiovascular consequences, including aortic aneurysms and aortic dissection. The conventional treatment comprises beta-blockers to mitigate the dilatation of the aorta and aortic surgery. The efficacy of contemporary medicinal and surgical interventions in Marfan syndrome has significantly enhanced mean life expectancy. International guidelines generally discourage physical activity for individuals with Marfan syndrome. Recent recommendations have created exclusions for these patients, indicating benefits from engaging in low-intensity physical activity exclusively. Aim of the study: The primary aim of this research is to elucidate the most recent management ideas pertaining to Marfan syndrome. Significant emphasis is placed on the importance and safety of physical activity in individuals afflicted with this disease. The risks linked to physical activity are addressed, however the advantages of particular activities are highlighted. Materials and methods: A review of the literature available in the PubMed database was performed, using the key words: „Marfan syndrome", „connective tissue disease”, „physical activity", „aortic aneurysm”, „FBN1”. Conclusion: The prognosis for patients with Marfan syndrome has markedly improved in the last years. Contrary to conventional guidance to refrain from physical activity, emerging research indicates that low-intensity exercise may be advantageous. Research on the safety and health implications of physical activity in patients with Marfan syndrome is exceedingly few. Current information indicates that moderate physical activity at a particular intensity may be safe in this condition. Additional study is necessary to offer targeted recommendations for patient training and enhance their long-term quality of life.

Very low levels of physical activity among patients hospitalized following hip fracture surgery: a prospective cohort study

Purpose The evidence supports early and intensive mobilization and physical activity for patients who are hospitalized following hip fracture. The objectives were to determine levels of physical activity among patients hospitalized following hip fracture surgery, and to explore the association between levels of physical activity and 30-day post-discharge readmission, and mortality. Materials and methods We collected data at two university hospitals in Denmark from March-June 2023. Patients were included on postoperative day (POD) 1 to 3. 24-h upright time was measured from inclusion to discharge using a thigh-worn accelerometer. 30-day readmission and mortality were verified by patient records. Results 101 patients with a mean (SD) age of 79.9(8.4) years were included. The median (IQR) 24-h upright time on POD2-6 ranged from 15(7:31) to a maximum of 34(16:67) mins. Within 30 days after discharge, 25 patients(25%) were readmitted or referred to an emergency ward and 3(3%) patients died (no clear association with upright time). Conclusions For patients hospitalized following hip-fracture surgery, the level of physical activity seems extremely low the first week, but it does not seem to influence the rate of readmissions. Considering evidence supporting physical activity during acute hospitalization, the low activity level in these patients calls for action. Clinicaltrials.gov-identifier NCT05756517.

Effects of physical activity on patients with posttraumatic stress disorder: A systematic review and meta-analysis of randomized controlled trials.

Although it is often known that physical activity can effectively reduce anxiety and despair, differing results have been found for patients with posttraumatic stress disorder (PTSD) symptoms. This study sought to comprehensively examine how physical activity affected the quality of sleep, anxiety, sadness, and PTSD in individuals suffering from PTSD. The Cochrane Library, PubMed, Web of Science, EMBASE, and Scopus databases in English were examined. Included were all randomized controlled trials (RCTs) that examined physical activity as a psychosocial remedy for PTSD sufferers. By the time of the meta-analysis search (February 2024), we had 12 RCT studies that met the eligibility requirements. The study's findings demonstrated that physical activity improved sleep quality (standardized mean differences [SMD] = -0.38, 95% CI [-0.59, -0.18], Z = 3.65, P = .0003), anxiety (SMD = -0.26, 95% CI [-0.47, -0.06], Z = 2.5, P = .01), depression (SMD = -0.19, 95% CI [-0.37, -0.01], Z = 2.09, P = .04), and PTSD (SMD = -0.34, 95% CI [-0.50, -0.17], Z = 3.99, P < .0001). Each intervention ≤ 60 (SMD = -0.52, I2 = 0%, P < .00001), frequency of interventions ≤ 2 per week (SMD = -0.44, I2 = 7%, P = .0004), intervention cycles > 10 (SMD = -0.46, I2 = 8%, P < .0001), and the yoga group (SMD = -0.44, I2 = 7%, P = .0004) had the best impact, according to subgroup analyses. Veterans with PTSD responded most significantly to physical activity (SMD = -0.60, I2 = 0%, P = .002). It was discovered that people with PTSD can benefit from physical activity as an adjuvant method to enhance their PTSD, anxiety, despair, and sleep quality. Yoga has been found through research to help the symptoms of people with PTSD more than other sports. Due to limitations such as small sample size and some heterogeneity in this meta-analysis, further confirmation through more scientific and objective RCTs is needed in order to obtain definitive conclusions on physical activity for patients with PTSD.

Physical activity in patients after bariatric surgery - a literature review

Physical activity in patients after bariatric surgery - a literature review

A comparative cross-sectional study of psychological distress, fatigue, and physical activity in patients with rheumatoid arthritis, systemic lupus erythematosus, and Sjögren's disease.

Anxiety and depression are common in patients with rheumatic diseases, but their impact across conditions like rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and primary Sjögren's disease (SjD) is still not well understood. This study aims to compare depression, anxiety, and fatigue, and their effects on disease activity and physical activity in these conditions. From January 2019 to March 2021, patients with RA, primary SjD and SLE were assessed consecutively in a monocentric cross-sectional study at the rheumatology outpatient clinic of the Hannover Medical School. Standardized questionnaires were used to assess depression, anxiety, fatigue, disease activity, functional impairment, and physical activity in these patients. Of 445 patients, 36.9% had RA, 32.8% SLE, and 30.3% SjD, with most being female (RA 76.2%, SLE 85.6%, SjD 87.4%). Depression (28.5%) and anxiety (31.2%) were common, particularly in SLE (28.8%) and SjD (36.3%) vs. RA (22%, p 0.002). Physical inactivity was higher in SLE (44.5%) and SjD (44.4%) than in RA (39.0%), especially in depressed patients (p 0.011). A significant proportion of patients retired early, especially in SLE (85%) and SjD (66%) vs. RA (49%, p 0.001). Disease activity correlated with psychological status (p < 0.05). Depression and anxiety are highly prevalent in RA, SLE, and SjD, particularly in SLE and SjD. The study highlights the need for early psychological evaluation and integrated care involving rheumatologists and mental health professionals to address these issues and improve physical and mental well-being.

Analysis of changes in PCSK9 and TNF-α concentrations in response to physical exercises using virtual reality in patients in the fifth stage of chronic kidney disease undergoing hemodialysis

BackgroundThe problem of reduced physical activity in patients with stage 5 Chronic Kidney Disease (CKD) is becoming more and more interesting in the medical community. One of the innovative solutions that can significantly increase patients’ motivation to exercise is the integration of physical training with virtual reality (VR) technology during hemodialysis. The aim of this study was to comprehensively assess the impact of regular physical activity using virtual reality on the concentration of plasma PCSK9 protein and TNF-α in patients with stage 5 CKD treated with hemodialysis.MethodsA prototype of the NefroVR system was used in the research project. The study group consisted of patients who were entrusted with the task of conducting training using the prototype of the NefroVR system.ResultsIn the conducted research, a significant decrease in PCSK9 protein and TNF-α concentration was observed in the study group after 3 months of exercises using virtual reality in hemodialysis patients.ConclusionRegular physical activity using innovative physiotherapy methods, such as virtual reality, contributes to the improvement of inflammatory parameters and may improve lipid homeostasis.Clinical trial numbernot applicable.

Cough and sputum symptoms reduce physical activity in patients with NTM pulmonary disease.

<sec><title>BACKGROUND</title>Although physical activity is an important outcome in patients with chronic respiratory disease, it has not been characterised in those with non-tuberculous mycobacterial pulmonary disease (NTM-PD). This study aimed to evaluate physical activity and its associated factors in patients with NTM-PD.</sec><sec><title>METHODS</title>This prospective observational study measured daily step counts using an accelerometer to assess physical activity (steps per day). We investigated serum C-reactive protein (CRP), incremental shuttle walk test distance (ISWD), Leicester Cough Questionnaire (LCQ), modified Medical Research Council (mMRC) dyspnoea scale, and chronic cough and sputum symptoms (CCS). Patients were divided into two groups based on the presence or absence of CCS, and their physical activity were compared. The association between physical activity and these variables was examined using multivariate analysis.</sec><sec><title>RESULTS</title>We included 131 patients, with a median daily step count of 3,960. Patients with CCS had significantly lower daily step counts than those without CCS (3,426 vs 4,567). Daily step count significantly correlated with age, mMRC dyspnoea grade, CRP level, ISWD, and LCQ. Multiple regression analysis showed that the daily step count was significantly associated with ISWD and CCS.</sec><sec><title>CONCLUSIONS</title>These results suggest that CCS should be considered when assessing physical activity in patients with NTM-PD.</sec>.

Association between the intensity of statin therapy and physical activity 1 year after acute coronary syndrome: a multicentre prospective cohort study in Switzerland

ObjectivesTo assess the association between the intensity of statin therapy and the level of physical activity in patients 1 year after an acute coronary syndrome (ACS).DesignProspective cohort study from the...

Impact of the Acti-Pair programme on physical activity in patients with prostate cancer: protocol of the Acti-Pair 2 stepped-wedge cluster randomised trial

Regular physical activity (PA) reduces morbidity and mortality in prostate cancer. Prescribing PA in cancer is a necessary awareness but is a real challenge in the case of prostate cancer....

Individualized Physical Activity Prescriptions for Children and Adolescents With Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

For improved health outcomes, children and adolescents with cancer must maintain physical activity. Individualized physical activity prescription is an effective way to promote physical activity in this group. We reviewed and meta-analyzed evidence on the effectiveness of individualized physical activity prescriptions for improving physical activity and other health outcomes among children and adolescents with cancer. Seven databases were searched from inception up to January 2024 for randomized controlled trials. Two researchers independently extracted data and assessed the quality of studies using the Risk-of-Bias tool. Data were pooled into Review Manager 5.3 for data synthesis and subgroup analyses. Seventeen randomized controlled trials were included. The systematic review summarized the characteristics of recent interventions. Meta-analyses showed that although individualized physical activity prescriptions had no overall effect on physical activity (n = 8 studies), anthropometry and body composition (n = 5), functional capacity (n = 3), quality of life (n = 8), fatigue (n = 3), and self-efficacy (n = 5), they improved cardiovascular fitness (n = 8, P = .02) and muscle strength (n = 8, P = .04). Subgroup analyses showed that studies providing 6-month interventions (P = .003) or such interventions combined with motivational interviewing (P = .002) reported significantly increased physical activity in patients. Individualized physical activity prescriptions appear to improve cardiovascular fitness and muscle strength in children and adolescents with cancer. High-quality studies providing long-duration interventions and motivational interviewing are needed for optimal physical activity programs for children and adolescents with cancer. The application of electronic devices should increase the types of physical activities for this group to further improve health outcomes.

The Role of Cardiac Rehabilitation in Promoting Lifestyle Modification Among Cardiovascular Patients: A Nationwide Cohort Study.

Cardiac rehabilitation (CR) is crucial for the secondary prevention of cardiovascular disease, primarily by promoting lifestyle modifications. However, its impact on lifestyle changes in the Korean population has not been well studied. This study analyzed data from the National Health Insurance Database to evaluate the effect of CR on lifestyle improvement in patients with cardiovascular disease. Patients who underwent coronary revascularization in 2017 were included. This study investigated whether the lifestyle habits of patients with cardiovascular disease who were physically inactive, obese, and smoked improved after coronary revascularization. To analyze whether CR affected each lifestyle factor, multiple regression analysis was performed, adjusting for socioeconomic and medical conditions as covariates. CR had a significant effect on the acquisition of regular physical activity among physically inactive patients before revascularization (odds ratio [OR]: 1.205, 95% confidence interval [CI]: 1.046-1.389). However, CR did not have a significant impact on smoking cessation in smokers (OR: 1.172, 95% CI: 0.890-1.545) and weight reduction in patients with obesity (OR: 1.104, 95% CI: 0.977-1.248). This nationwide study showed that CR after coronary revascularization significantly improved physical activity in patients with cardiovascular disease. However, CR had no significant effect on smoking cessation or weight reduction, indicating a need for more comprehensive approaches to address these lifestyle factors.

Eating habits and physical activity in patients with colorectal cancer in a city of Mato Grosso

Colorectal cancer has been the cause of death in men and women before the age of 50. It is known that tumor development is influenced by several factors, such as obesity, diabetes, physical inactivity and bad eating habits. The present study aimed to analyze the daily habits of patients with colorectal cancer in a local hospital. The study was longitudinal and descriptive with participants diagnosed between 2019 and 2023 with tumors in the colon and rectum that were not derived from metastasis. Using questionnaires, based on the "Food Guide: how to have a Healthy Diet" from the Ministry of Health (Brazil), adding questions about practicing physical activity. The data on weight and height was extracted from medical records, and Body Mass Index (BMI) divided patients into two groups: control group (BMI between 18.6 kg/m2 and 24.9 kg/m2) and overweight/obese (BMI ≥ 25 kg/m2). The data were arranged as relative and absolute frequencies and analyzed using the GraphPad Prism® 8 program using the chi-square (χ2) statistical test with a minimum acceptable significance level of p &lt; 0.05. According to the results, it was noted that most participants need to pay attention to their eating habits according to the instrument score and daily physical activity and that a very small portion have a considerably healthy lifestyle.

A Novel Behavioral Intervention to Enhance Physical Activity for Older Veterans in a Skilled Nursing Facility.

Physical activity levels during skilled nursing facility (SNF) rehabilitation fall far below what is needed for successful community living and to prevent adverse events. This feasibility study's purpose was to evaluate the feasibility, acceptability, and preliminary effectiveness of an intervention designed to improve physical activity in patients admitted to SNFs for short-term rehabilitation. High-Intensity Rehabilitation plus Mobility combined a high-intensity (i.e.,high weight, low repetition), progressive (increasing in difficulty over time), and functional resistance rehabilitation intervention with a behavioral economics-based physical activity program. The behavioral economics component included five mobility sessions/week with structured goal setting, gamification, and loss aversion (the idea that people are more likely to change a behavior in response to a potential loss over a potential gain). SNF physical therapists, occupational therapists, and a mobility coach implemented the High-Intensity Rehabilitation plus Mobility protocol with older Veterans (n = 18) from a single SNF. Participants demonstrated high adherence to the mobility protocol and were highly satisfied with their rehabilitation. Treatment fidelity scores for clinicians were ≥95%. We did not observe a hypothesized 40% improvement in step counts or time spent upright. However, High-Intensity Rehabilitation plus Mobility participants made clinically important improvements in short physical performance battery scores and gait speed from admission to discharge that were qualitatively similar to or slightly higher than historical cohorts from the same SNF that had received usual care or high-intensity rehabilitation alone. These results suggest a structured physical activity program can be feasibly combined with high-intensity rehabilitation for SNF residents following a hospital stay.

Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus

Physical activity is an adjunctive therapy that improves symptoms in people living with systemic lupus erythematosus (SLE), yet the mechanisms underlying this benefit remain unclear. We carried out a cohort study of 123 patients with SLE enrolled in the California Lupus Epidemiology Study (CLUES). The primary predictor variable was self-reported physical activity, which was measured using a previously validated instrument. We analyzed peripheral blood mononuclear cell (PBMC) single-cell RNA sequencing (scRNA-seq) data available from the cohort. From the scRNA-seq data, we compared immune cell frequencies, cell-specific gene expression, biological signalling pathways, and upstream cytokine activation states between physically active and inactive patients, adjusting for age, sex and race. We found that physical activity influenced immune cell frequencies, with sedentary patients most notably demonstrating greater CD4+ T cell lymphopenia (Padj=0.028). Differential gene expression analysis identified a transcriptional signature of physical inactivity across five cell types. In CD4+ and CD8+ T cells, this signature was characterized by 686 and 445 differentially expressed genes (Padj<0.1). Gene set enrichment analysis demonstrated enrichment of proinflammatory genes in the TNF-α signalling through NF-kB, interferon-γ (IFN-γ), IL2/STAT5, and IL6/JAK/STAT3 signalling pathways. Computational prediction of upstream cytokine activation states suggested CD4+ T cells from physically inactive patients exhibited increased activation of TNF-α, IFN-γ, IL1Β, and other proinflammatory cytokines. Network analysis demonstrated interconnectivity of genes driving the proinflammatory state of sedentary patients. Findings were consistent in sensitivity analyses adjusting for corticosteroid treatment and physical function. Taken together, our findings suggest a mechanistic explanation for the observed benefits of physical activity in patients with SLE. Specifically, we find that physical inactivity is associated with altered frequencies and transcriptional profiles of immune cell populations and may exacerbate pathologic inflammatory signalling via CD4+ and CD8+ T cells. This work was supported by the US National Institutes of Health (NIH) (R01 AR069616, K23HL138461-01A1, K23AT011768) the US CDC (U01DP0670), and the CZ Biohub.

Rheumatoid arthritis treatment: Is exercise a game changer?

It is known that physical activity and exercise have many effects on patients with rheumatoid arthritis, such as reducing pain, stiffness, and fatigue and having positive effects on the development of complications related to the disease. However, despite all this information, the level of exercise and physical activity in patients with rheumatoid arthritis is lower than in healthy individuals. This may be due to reasons such as thinking that the disease will worsen, not having enough information about exercises, and not being supported enough by healthcare professionals and family in this regard. This review summarized the basic effects of exercises and recommended exercise programs.

Physical Activity in Patients With Chronic Kidney Disease: The Effects of Caregivers and Residential Factors.

Introduction Physical inactivity is common in chronic kidney disease (CKD) patients; several patient- and disease-related factors are linked to a sedentary lifestyle, but social and environmental influences remain unexplored. This study evaluates the level of physical activity in patients with CKD and investigates the associations with caregivers' physical activity levels, characteristics of the residential environment, and objective measures of exercise capacity. Methods Eighty CKD patients (20 per CKD stage 2-4) were included; patients and their carers filled out the International Physical Activity Questionnaire (IPAQ), questionnaires about residential environment and past exercise habits. The CKD patients also performed a 30-sec sit-to-stand-test (30-STS) as a measure of exercise capacity. Results According to the IPAQ-score, CKD patients were largely inactive (only 10% reported health-enhancing activity levels); no differences were found between CKD stages. The 30-STS was also impaired, and thenumber of repetitions significantly decreased with advancing CKD stages (14.2±2.9 vs. 12.6±5.4 vs. 10.4±3.3 vs. 10.5±3.5; p=0.008). Carers were also highly inactivebut still had higher physical activity compared to patients (moderate intensity metabolic equivalents (METS) p=0.03, vigorous intensity METS p=0.053); no correlation between carers' and patients' physical activity was noted (p=0.702). Patients' physical activity was associated with residential factors: living in a detached house compared to an apartment (p=0.013 for moderate intensity and p=0.017 for vigorous METS), having a garden (p=0.019 for moderate intensity and p=0.022 for vigorous METS) and accessing house by stairs (p=0.037 for vigorous METS), were associated with higher physical activity. Conclusions Physical activity was significantly reduced in CKD patients, irrespectively disease stage. Carers were also highly inactive, but no association was found between the patients' and carers' daily activities. Residential characteristics were the only factors found to be associated to patients' physical activity levels. Personalized, supportive interventions are required, taking into account the patients' social support and microenvironment, in order to increase the physical activity level in this population.

Effectiveness of a digital health and financial incentive intervention to promote physical activity in patients with type 2 diabetes: study protocol for a randomised controlled trial with a nested qualitative study—ACTIVATE trial

BackgroundThe prevention of type 2 diabetes (T2DM) is recognised as a health care priority in the UK. In people living with T2DM, lifestyle changes (e.g. increasing physical activity) have been shown to slow disease progression and protect from the development of associated comorbidities. The use of digital health technologies provides a strategy to increase physical activity in patients with chronic disease. Furthermore, behaviour economics suggests that financial incentives may be a useful strategy for increasing the maintenance and effectiveness of behaviour change intervention, including physical activity intervention using digital health technologies. The Milton Keynes Activity Rewards Programme (MKARP) is a 24-month intervention which combines the use of a mobile health app, smartwatch (Fitbit or Apple watch) and financial incentives to encourage people living with T2DM to increase physical activity to improve health. Therefore, this randomised controlled trial aims to examine the long-term acceptability, health effects and cost-effectiveness of the MKARP on HbA1c in patients living with T2DM versus a waitlist usual care comparator.MethodsA two-arm, single-centre, randomised controlled trial aiming to recruit 1018 participants with follow-up at 12 and 24 months. The primary outcome is the change in HbA1c at 12 months. Secondary outcomes included changes in markers of metabolic, cardiovascular, anthropometric, and psychological health along with cost-effectiveness. Recruitment will be via annual diabetes review in general practices, retinal screening services and social media. Participants aged 18 or over, with a diagnosis of type 2 diabetes and a valid HbA1c measurement in the last 2 months are invited to take part in the trial. Participants will be individually randomised (1:1 ratio) to receive either the Milton Keynes Activity Rewards Programme or usual care. The intervention will last for 24 months with assessment for outcomes at baseline, 12 and 24 months.DiscussionThis study will provide new evidence of the long-term effectiveness of an activity rewards scheme focused on increasing physical activity conducted within routine care in patients living with type 2 diabetes in Milton Keynes, UK. It will also investigate the cost-effectiveness of the intervention.Trial registrationISRCTN 14925701. Registered on 30 October 2023.

Physical activity in patients with chronic venous insufficiency: Its relation with disease severity, pain, fatigue, and functionality

Purpose: Chronic venous insufficiency (CVI) is a progressive disease of the venous system caused by a variety of factors that impair the return of venous blood to the heart. The aim of the study was to evaluate the physical activity level in patients with CVI and its relation with disease severity, pain, fatigue, functionality. Methods: In all, 105 CVI patients (28.6% male, 71.4% female, mean age was 44.91±10.74 years) were enrolled in this study. Physical activity was evaluated with the International Physical Activity Questionnaire-Short Form (IPAQ-SF); disease severity, by Venous Clinical Severity Score (VCSS); the intensity of pain was determined by the Visual Analog Scale (VAS); fatigue level with the Fatigue Severity Scale (FSS); functionality was assessed with the Lower Extremity Function Scale (LEFS). Results: There was a significant negative correlation between IPAQ-SF-vigorous and VCSS, VASrest, VASactivity, VASnight (r: -0.818, p

Personality traits and physical activity in patients with gambling disorder attending a rehabilitation center. An observational study.

Problem gambling is associated with various negative health behaviors, such as physical inactivity. However, physical activity may also be used as a coping mechanism to manage stress and anxiety. This study aimed to investigate whether personality traits are associated with physical activity levels in individuals attending a rehabilitation center for gambling disorder (GD). An observational study was conducted in 71 patients belonging to a Gamblers' Recovery Association. All of them completed a socio-demographic questionnaire, the Exploratory Personality Questionnaire-III (CEPER-III) and the International Physical Activity Questionnaire (IPAQ). Comparisons with general population and association between personality traits and physical activity were analyzed. The study sample predominantly consisted of male participants (91.5%), with the majority having an educational attainment of compulsory schooling or less (70.4%). Additionally, a substantial proportion of participants exhibited school-related problems (43.7%) and had a history of mental health issues (33.8%). Compared to the general population, individuals in the CEPER-III cohort demonstrated significantly lower scores in the following personality traits: paranoid (p < 0.05), histrionic (p < 0.001), narcissistic (p < 0.001), passive-aggressive (p < 0.05), and sadistic (p < 0.01). Multivariate logistic regression analysis indicated that the antisocial, borderline, obsessive-compulsive, and self-destructive personality traits were significantly associated (p < 0.05) with the level of physical activity. This study found a link between personality traits and physical activity levels in patients with GD. Gamblers with higher scores on obsessive-compulsive and self-destructive personality traits were more likely to fall into the moderate-high physical activity group. In contrast, those with higher scores on antisocial and borderline personality traits were more likely to be classified in the low physical activity group.

Experience of physical activity in patients with stroke: A qualitative meta-synthesis.

Inadequate physical activity (PA) is increasingly common among stroke patients, we aim to comprehensively analyze the experience of stroke patients delivering physical activity, understand the obstacles and promoting factors of physical activity, and summarize clinical management strategies. An electronic search of PubMed, Web of Science, Cochrane Library, ProQuest, SinoMed, CNKI, and WanFang Database was conducted for qualitative studies on the experience of PA in stroke patients. The review was appraised using the Joanna Briggs Institute methodology, the subsequent findings were synthesized via the Thomas and Harden approach and the credibility of the research results was evaluated by the CERqual tool. Six thousand five hundred forty-nine findings were yielded through the search, ultimately 11 studies were included through screening, a total of 194 stroke patients participated in the study, and 3 synthesized themes that emerged were identified: barriers to PA, facilitators to PA, and strategies to improve compliance with physical activity in stroke patients. All selected articles were of medium quality and all themes were of medium or high quality. The experience of PA among stroke patients should be given more attention. Healthcare professionals should provide physical activity-related knowledge education, social support, personalized care, improved environments, and create more opportunities for PA. In the future, more tailored interventions should be carried out to develop PA habits and improve compliance.