The chronic diseases constitute pathological social phenomena as they have an impact on the organic construction for individuals; They make their roles and functions in the society regress and weak due to the results made by these diseases on their social, psychological, and economic lives as well. They make several problems which lead to struggles be it the patient with himself or with people surrounding him. Amongst the most known and dangerous diseases is kidney failure which is included at the last stage of kidney disease; The kidney completely loses its function and work leading by this to dialysis with medical equipments and apparatus. Undoubtedly, the patient, at the time of being acquainted with the disease, is exposed to psychological trauma such as: not accepting and not adapting to the disease. Following by social problems by time owed to the fact that the patient will not play his ordinary role whether inside the family or outside it leading him accordingly to pressures preventing him from adapting to the social reality. Therefore, we pose the following question: What are the major psychological and social problems that patients with kidney failure are suffering from?