Patent Trends Research Articles

An Overview on patenting trends and technology commercialization practices in the university Technology Transfer Offices in USA and China

The Technology Transfer Office is critical in translating university research into commercial value. This research paper analyzes the performances of university Technology Transfer Office models as well as their technology transfer mechanisms. The first step of this research project involves conducting patent information searches on databases to investigate academic patenting activities in the USA and China. Many Technology Transfer Offices, have similar intellectual property licensing practices and the involvement of industrial partners throughout the commercialization process. However, during the comparison it is found that the Technology Transfer Office working models varied in several ways. The main difference is that the pace at which patenting is accomplished in the USA and Chinese universities is far more sophisticate. Because of substantial resources and government support, Proof of Concept funding at various stages of technological maturity is steadily developing at universities in the USA and China. Furthermore, both USA and Chinese universities are very active in teaching and incentivizing their faculty and students about the importance of academic entrepreneurship and are well-versed with skilled technology transfer professionals who have all the necessary skills to transfer technology.

Today’s baton and tomorrow’s vision: The effect of strengthening patent examination system on corporate innovation strategies

This study examines the role of strengthened patent examination system in shaping firms’ innovation activities. We find that strengthening patent examination system discourages the strategic use of patents and stimulates efforts toward substantive innovation that develops novel technologies. We identify two boundary conditions, namely technology intensity and ownership type, which regulate the impact of the strengthened patent examination system on firms’ innovation strategies. We further reveal that the post-reform changes in corporate innovation strategies lead to an improvement in the overall quality of innovation output, which results in improved firm financial performance. This study contributes to the research on the impact of patent system changes on innovation, and also the research on firm patenting trends by linking to standards of patent examination. Our findings provide valuable insights for policymakers and scholars in patent policy reforms.

신선 농산물의 수확 후 포장 및 저장 기술과 관련된 특허 동향 분석

Patents for postharvest technology of fresh fruits, vegetables and mushrooms fluctuated in their filing number until the 2000s, but then there has been a steady increase in the 2010s, indicating that the technology has high growth potential in the international agricultural market. Using 551 valid patents for fresh fruits and 337 for fresh vegetables of 5 countries, patent trend of postharvest technology was analyzed in this study with two categorized technologies as packaging and storage. In Korea, patents from national research institutes such as the Korea Food Research Institute and Korea (Rural Development Administration) are dominated, and a number of patents for the postharvest storage of fresh vegetables by Mitsui Chemicals, a Japanese chemical company, have been registered. Agrofresh, a multinational company in the USA, holds a number of patents for postharvest storage of fresh fruit not only in its own country, but also in Japan and Europe. Postharvest technology of fresh fruits and vegetables was found to has a number of patents, mainly from national research institutes and multinational corporations, and this suggests that R&D and commercialization of the technologies are actively taking place.

전력설비 특허 동향 분석 및 부상기술 동향에 대한 고찰

The electric power facility industry were started with all transmission and distribution devices, from power plants that produce electricity to consumers who use electricity. Major domestic power companies are concentrating on decarbonization, decentralization, digitalization, deregulation, and energy democratization as the policy direction to implement the decarbonization strategy. Although it seems a bit complicated, the reality is that the strategy of increasing the proportion of new and renewable power generation through the expansion of new and renewable business is the main issue. Therefore, as the main DC power source of renewable energy sources is connected to the transmission and distribution system, it is expected that the investment related to the safe system operation and DC facility will continue to increase. In this regard, the renewable and DC-related power facility industry is also expected to grow together. In this paper, based on patent information, the recent patent trends in the electric power facility field of IP5 countries in the United States, Europe, Japan, China, and Korea were analyzed quantitative and qualitative, respectively. The emerging technology trends were analyzed through activity and technology index analysis.

Discovery, Development, Inventions, and Patent Trends on Mobocertinib Succinate: The First-in-Class Oral Treatment for NSCLC with EGFR Exon 20 Insertions.

The majority of lung cancers are non-small-cell lung cancer (NSCLC) having a low survival rate. Recent studies have indicated the involvement of epidermal growth factor receptor (EGFR) oncogene mutations like EGFR exon 20 insertions (EGFRex20ins) mutation among NSCLC patients. The response of patients of NSCLC with the EGFRex20ins mutation to the currently available EGFR inhibitor is negligible. Mobocertinib is the first oral treatment that has been approved by the USFDA, on 15 September 2021, to treat NSCLC with the EGFRex20ins mutation. This patent review discusses the inventions and patent literature of mobocertinib that will help the scientific community to develop additional and improved inventions related to mobocertinib. The structure of mobocertinib was first reported in 2015. Therefore, this article covered the patents/patent applications related to mobocertinib from 2015 to 25 October 2021. The patent search revealed 27 patents/patent applications related to compound, method of treatment, salt, polymorph, process, composition, and drug combinations of mobocertinib. The authors foresee an exciting prospect for developing a treatment for NSCLC with EGFRex20ins mutation, and other cancers employing a combination of mobocertinib with other approved anticancer agents. The inventions related to novel dosage forms, processes, and intermediates used in the synthesis of mobocertinib are also anticipated.

Global Patent Trends in New Breeding Technology for Crop Improvement

Global Patent Trends in New Breeding Technology for Crop Improvement

How Patents Influence Market Value of Industrial Enterprises' Assets?

Scientists and engineers are continuously patenting innovative ideas such as inventions, industrial designs, and utility models. It is therefore relevant to pose the question of the influence of intellectual property in the field of innovative technologies on the market value of the assets of industrial enterprises.
 We analyse the dependence of the results of intellectual activity in the field of advanced technologies on the capitalization of innovative industrial production after the adoption of the developed technologies. We consider patent landscapes, analyse research publications, and study the dependence of financial indicators on the results of intellectual activity at enterprises producing computers, optics and electronic equipment.
 Our research methodology is based on the statistical analysis of the dependence of the financial results of industrial enterprises on the actual application of the results of intellectual activity to the technological process. We define the object of analysis by citing research articles and surveys from the WoS database. The patent landscape is assessed using data from commercial information systems such as Orbit Intelligence (Questel) and Amadeus (Bureau van Dijk, Moody’s Analytics) that make it possible to visually show the links between patent activity and technological trends in the computer and electronic technology industries.
 The research results shall be useful for assessing the effectiveness of employing patents in manufacturing and the prospects of improving production technologies for the formation of corporate innovative technological policy.
 We conclude that the use of information on patent trends is an effective tool for increasing the competitiveness of enterprises producing electronic equipment. The priority financing of innovative technologies ensures the sustainable development of the manufacturing industry and have a positive impact on the profitability of enterprise assets.

Research on the Patent Trend of OLED Technology

Research on the Patent Trend of OLED Technology

Patent landscape report on dental implants: A technical analysis.

Significant research and development (R&D) has been conducted to make the best dental implants while developing various patent applications and registrations. In this study, we evaluated the current status of patents on dental implants and identified the future direction of R&D progress. A total of 29 711 patents related to dental implants were reviewed. These were published between 1909 and 2020 and retrieved from the Derwent Innovation patent database. The patents were grouped into three categories depending on the implant components: fixture, abutment, and artificial teeth. The category with most patents was "abutment," and the most cited patent was "screw-type dental implant anchor." Global patenting trends over the past 20 years showed that both applicants and applications increased in the early 2010s; however, these have since been on the decline. Currently, the United States holds the largest number of patents, and Nobel Biocare Holding AG is the top assignee. Technic maturation prediction analysis showed that the current dental implant technology is in the "decline stage." Trend analysis of the dental implant patent indicates the main contributors of development are profit-oriented companies. Recent reduction in the number of new patent applications suggests the technology is in the mature declining stage. The emergence of new materials or technologies that may close the gap in clinical unmet needs would reverse the trend.

AI Technology Application in Medical Care of NSCLC Based on Patent Trend Analysis

Abstract The patent trend analysis provides sound knowledge about the possibility of exploring potential innovation/R&D and gives an insight into which countries and companies are mostly investing in artificial intelligence (AI) technologies involved with non-small cell lung cancer (NSCLC) medical care. By comparing patent indicators changes of two decades from 2001 to 2020, the most active countries and companies are identified to provide perceptions of global patent variations. In line with this, we apply a comprehensive software INNOVUE to analyze the patent trend based on the Worldwide Patent Office database. According to previous research, 315 patents are selected as the appropriate patent analysis data. The analysis result is a series of trend maps that show the trend of patent development from the early stage to current changes. This study findings evaluate government’s/company’s concern and motivation about the investment in R&D capability of AI technology related patents, and indicate who plays the main role around the world regarding the application of AI combined with NSCLC medical treatment. JEL classification numbers: C80, D81, E27. Keywords: Patent trend analysis, Artificial intelligence technologies, NSCLC.

Semantic patent analysis with Amazon Web Services

Semantic analysis of the patent array allows us to solve several modern problems: (1) Clustering of the patent array. This information can be useful for identifying patent trends, key modern technologies, and predicting the demand for technologies in the future period; (2) Automation of the work of the patent office expert. Based on a full-text query (the text of a patent application), a search for analogous patents can be performed. This study describes a developed software that provides the possibility of clustering the patent array (topic modeling), identifying groups of related patents (not based on patent classification but on the basis of key terms/phrases extracted from the texts), and a search for patents using AWS technologies.

A Study on the Trends of Patents Concerning the Hair Loss Prevention and Improvement Technologies Using AI

A Study on the Trends of Patents Concerning the Hair Loss Prevention and Improvement Technologies Using AI

Discovery, Development, and Patent Trends on Molnupiravir: A Prospective Oral Treatment for COVID-19.

The COVID-19 pandemic needs no introduction at present. Only a few treatments are available for this disease, including remdesivir and favipiravir. Accordingly, the pharmaceutical industry is striving to develop new treatments for COVID-19. Molnupiravir, an orally active RdRp inhibitor, is in a phase 3 clinical trial against COVID-19. The objective of this review article is to enlighten the researchers working on COVID-19 about the discovery, recent developments, and patents related to molnupiravir. Molnupiravir was originally developed for the treatment of influenza at Emory University, USA. However, this drug has also demonstrated activity against a variety of viruses, including SARS-CoV-2. Now it is being jointly developed by Emory University, Ridgeback Biotherapeutics, and Merck to treat COVID-19. The published clinical data indicate a good safety profile, tolerability, and oral bioavailability of molnupiravir in humans. The patient-compliant oral dosage form of molnupiravir may hit the market in the first or second quarter of 2022. The patent data of molnupiravir revealed its granted compound patent and process-related patent applications. We also anticipate patent filing related to oral dosage forms, inhalers, and a combination of molnupiravir with marketed drugs like remdesivir, favipiravir, and baricitinib. The current pandemic demands a patient compliant, safe, tolerable, and orally effective COVID-19 treatment. The authors believe that molnupiravir meets these requirements and is a breakthrough COVID-19 treatment.

A text mining-based approach for the evaluation of patenting trends on nanomaterials

A text mining-based approach for the evaluation of patenting trends on nanomaterials

When Cyclodextrins Met Data Science: Unveiling Their Pharmaceutical Applications through Network Science and Text-Mining.

We present a data-driven approach to unveil the pharmaceutical technologies of cyclodextrins (CDs) by analyzing a dataset of CD pharmaceutical patents. First, we implemented network science techniques to represent CD patents as a single structure and provide a framework for unsupervised detection of keywords in the patent dataset. Guided by those keywords, we further mined the dataset to examine the patenting trends according to CD-based dosage forms. CD patents formed complex networks, evidencing the supremacy of CDs for solubility enhancement and how this has triggered cutting-edge applications based on or beyond the solubility improvement. The networks exposed the significance of CDs to formulate aqueous solutions, tablets, and powders. Additionally, they highlighted the role of CDs in formulations of anti-inflammatory drugs, cancer therapies, and antiviral strategies. Text-mining showed that the trends in CDs for aqueous solutions, tablets, and powders are going upward. Gels seem to be promising, while patches and fibers are emerging. Cyclodextrins’ potential in suspensions and emulsions is yet to be recognized and can become an opportunity area. This is the first unsupervised/supervised data-mining approach aimed at depicting a landscape of CDs to identify trending and emerging technologies and uncover opportunity areas in CD pharmaceutical research.

Innovations and Patent Trends in the Development of USFDA Approved Protein Kinase Inhibitors in the Last Two Decades.

Protein kinase inhibitors (PKIs) are important therapeutic agents. As of 31 May 2021, the United States Food and Drug Administration (USFDA) has approved 70 PKIs. Most of the PKIs are employed to treat cancer and inflammatory diseases. Imatinib was the first PKI approved by USFDA in 2001. This review summarizes the compound patents and the essential polymorph patents of the PKIs approved by the USFDA from 2001 to 31 May 2021. The dates on the generic drug availability of the PKIs in the USA market have also been forecasted. It is expected that 19 and 48 PKIs will be genericized by 2025 and 2030, respectively, due to their compound patent expiry. This may reduce the financial toxicity associated with the existing PKIs. There are nearly 535 reported PKs. However, the USFDA approved PKIs target only about 10–15% of the total said PKs. As a result, there are still a large number of unexplored PKs. As the field advances during the next 20 years, one can anticipate that PKIs with many scaffolds, chemotypes, and pharmacophores will be developed.

Analysis of Patent Trends for Fire Protection Technology based on IoT and ICT Technology

Technology for the 4<sup>th</sup> Industrial Revolution, including ICT, IoT, and big data, has been combined with various other technologies. As an example, these technologies combined with fire protection technology can help protect lives and minimize property damage due to fires. In this study, the patents for fire protection technology using IoT and ICT technologies were investigated from 1999 to 2018 in Korea, the United States, Japan, and Europe. The technology patents were analyzed for international patent status and technological competitiveness by country. Although there was a slow increase in the overall number of patents for the fire protection technology from 1999 to 2014, the number has increased rapidly since 2015. The analysis in this study was intended to afford basic data on existing research to understand the trend and impact of the incorporation of the technology for the 4<sup>th</sup> Industrial Revolution into extant technology.

Trends in Surgical Patents Held by Surgeons From 1993 to 2018.

This study aims to quantify the number of patent-holding surgeons and determine their specialty demographics. The number of intellectual property filings related to surgery has exponentially increased over the past 40 years, yet surgeon inventor status among these inventions remains poorly defined. A query of the United States Patent and Trademark Office (USPTO) Patent Full-Text and Image Database was performed over the years 1993 to 2018. Patents related to surgery were defined as surgical devices, implantables, dressings, introducers, and sterilization equipment based on Cooperative Patent Classification (CPC) code. Inventor names were cross-indexed with names of active Fellows in the American College of Surgeons (FACS) as of 2019. Surgeon inventors were identified and differences between specialty and sex were evaluated. A total of 275,260 patents related to surgery were issued over the study period. The number of surgical patents has increased by 462% from 4593 per year to 21,241 per year. A total of 9008 patents were held by a total of 2164 surgeons (4% of FACS). This represents 3.3% of all surgical patents with a mean of 5 patents (range 1-346) per patent-holding surgeon. Specialties with the largest number of patent holders include neurosurgery (9%) and orthopedic surgery (8%). Ninety-seven percent of patent-holding surgeons were male. 3.3% of patents related to surgery involve a surgeon inventor, and although the number of surgical patents has shown an exponential increase, surgeon involvement in these inventions has grown minimally. Surgical innovation training may offer an opportunity to reduce these discrepancies and increase surgeon involvement as patent holders.

Patented technologies for schistosomiasis control and prevention filed by Chinese applicants

BackgroundMany valuable and productive patented technologies have been developed to control schistosomiasis in China in the past 70 years. We conducted a research to analyse patented technologies for schistosomiasis control and prevention filed by Chinese applicants for determining the future patent layout.MethodsThe patent databases of China National Intellectual Property Administration and Baiten were comprehensively searched, and patented technologies for schistosomiasis control and prevention, published between January 1950 and December 2020 filed by Chinese applicants were sorted on 30 December 2020. The patent types, technical fields, and patent development trends were analysed using patent indexing.ResultsThere are 184 valid schistosomiasis control technology patents, among them 128 invention patents. The patents related to schistosomiasis control and prevention technology have gone through the germination, growth, and maturity stages. These phases correspond with three phases in schistosomiasis control in China. The main technical aspects were fundamental research (n = 37), detection (n = 13), chemotherapy (n = 61), and armamentarium/devices (n = 73), of which the number of patents for detection for diagnosis was smaller. The top three specialised technical fields for patents subgroups, focusing on antiparasitic agents, DNA or RNA, vectors and medicines, of which schistosomicides are the major dominant subgroup.ConclusionsWe recommend that technologies to be patented for schistosomiasis control and prevention be focused on detection, preliminary studies for molecular detection methods should be significantly enhanced, and patent layout must be performed, which will, in turn, promote accuracy of early diagnosis, not only in humans but also in livestock. It is necessary to develop more anti-schistosomal drugs safely and effectively, exceptionally eco-friendly molluscicides and herbal extracts anti-schistosomes, improve treatment, develop vaccines for use in humans.Graphic abstract

Scope of Cloud Computing in Business: A Compendious and Methodical Analysis of Trends in Publications and Patents

Cloud Computing was a disruptive technology that reshaped the entire global industry, decentralizing the operational exchange and use of data and information. More companies are transitioning to a cloud-based infrastructure and are shifting some basic as well as advanced functionalities to it due to its salient features such as security, availability, scalability and popularity. Nevertheless, there is uncertainty attached to its limitations considering the possible saturation of the ceiling of growth and subsequent maturity of the technology’s potential. Therefore, it is essential to grasp the scope of the technology to be ready for the prospective trends and changes, as well as to channel its full incremental potential. For this, an elucidated statistical analysis of the technology is conducted, including the assessment of the trends of publications and patents signifying the evolution of the technology, its projected time of maturity, and finally, a befitting evidential roadmap for its future. This original work aims to add value by analyzing the numerical information concerning the growth of the technology over the years since its inception, and subsequently construct a detailed plan to adapt business objectives to the possible tapering of the growth curve of Cloud and build a suggestive and tentative contingency plan for the stage of technological maturity. Our finding indicates that Cloud technology may reach its maturity sooner than expected and an investment today might give the companies a competitive edge early on in the era of technological advancements and uncertainty.