Abstract: Objective: This study aimed to predict the orientation of the prosthetic trochlear angle (PTA) relative to the quadriceps line of force (QLF) in kinematically aligned total knee arthroplasty (KA-TKA) by using preoperative radiographic parameters. Methods: This study included 144 patients who underwent KA-TKA with a femoral component designed for mechanical alignment (MADFC), with a PTA of 6°. Radiographic parameters, including the lateral distal femoral angle (LDFA) and the QLF^FMA (quadriceps line of force–femoral mechanical axis angle), were measured pre- and postoperatively. We developed and validated a formula to predict PTA orientation based on these values: “X = QLF^FMA−(PTA−(90°−LDFA))”, where values of x > 0° predict a lateral PTA orientation, while x < 0° predicts a medial PTA. Results: The formula accurately predicted PTA orientation in 100% of the cases, with a difference between the predicted and actual PTA values of <0.5° in 75% of the cases. Patients with an LDFA < 86° and lower QLF^FMA values were identified as at risk for medial PTA orientation, which can affect patellar tracking. Conclusions: Our formula offers a reliable preoperative tool for predicting PTA orientation in KA-TKA, aiding in component selection and alignment strategies to improve patellofemoral function and patient outcomes.
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