Abstract One of the basic fluid mechanics problems of fluid flows over a revolving disk has both theoretical and real-world applications. The flow over a rotating disk has been the subject of numerous theoretical studies because it has many real-world applications in areas like rotating machinery, medical equipment, electronic devices, and computer storage. It is also crucial for engineering processes. Therefore, this article deals with a time-independent water-based hybrid nanofluid flow containing copper oxide and silver nanoparticles past a spinning disk. The Newtonian flow is taken into consideration in this analysis. The influence of magnetic field, thermophoresis, nonlinear thermal radiation, Brownian motion, and activation energy has been considered. The present analysis is modeled in a partial differential equation form and is then converted to ordinary differential equations using appropriate variables. A numerical solution using the bvp4c technique is accomplished using MATLAB software. The current results are matched with the previous literature and established a close relationship with previous studies. The purpose of this investigation is to numerically investigate the time-independent hybrid nanofluid flow comprising copper oxide and silver nanoparticles over a rotating disk surface. The results show that the increased magnetic parameters increase the friction force at the surface, which decreases the radial and azimuthal velocity distribution. At the sheet surface, the radial velocity of the hybrid nanofluid shows dominant performance compared to the nanofluid. On the other hand, the magnetic factor has dominant behavior on the azimuthal velocity component of the nanofluid flow compared to the hybrid nanofluid flow. The higher volume fraction and magnetic factor enhance the skin friction at the disk surface. Furthermore, greater surface drag is found for the hybrid nanofluid flow. The higher solid volume fraction, temperature ratio, and Biot number enhance the rate of heat transmission. Also, a higher rate of heat transmission is observed for the hybrid nanofluid flow.