The waiting hall is an important part for railway passenger station . To optimize and analyze the usage of waiting hall has great significance for improving operation efficiency of railway passenger station. Based on the research on the passenger volume and passenger flow construction, distribution regularities of passenger arrival time, passenger waiting time and the capacity of checking tickets windows can be obtained. By analyzing the distribution function of the above regularities, methods of calculating the efficient time of passengers occupying waiting halls can be achieved, so is the minimum departure time interval for trains in the same waiting area. On the basis of optimization and analysis of large scale railway passenger stations, algorithm for passenger stream lines of different platforms can be obtained and 0-1 planning model of the minimum waiting areas divided can be established. Based on the above work, constrains on whether there exist parallel operations for railway staffs are established , a nd phrases are divided into several time blocks , t he object function is the balance usage of waiting halls in large scale railway stations in one day and the shortest passenger stream lines in waiting halls , then a multiple-objective model on o peration a rrangement for waiting halls of large scale railway passenger stations is proposed , and its o ptimal algorithm is also present. Finally, a case study is carried out to verify the validity, objectivity and applicability of this model and its algorithm through calculated and analyzed practical data based on Lanzhou railway station. Optimal results show that the model on o peration a rrangement for waiting hall in large scale railway passenger stations can reach the usage balance of waiting halls and the shortest passenger stream lines , t he maximum difference between simulation passenger flow volume of each waiting hall and actual waiting passenger flow volume is 29 6 , and t he m in imum difference is 131 .To the railway stations which have mixed or sub-end arrangement and which have disorder passenger stream lines, more efficient results can be achieved with optimal model in the paper.