The segmentation of medical images is a significant challenge for computer vision and medical techniques. In the lungs, the difficulty is mainly due to the presence of lung diseases, different dimensions of the lung, and different types and configurations of medical imaging devices. Computed tomography (CT) is a tool to aid clinical diagnosis; several systems based on computer-aided diagnostics (CAD) are developed or enhanced from CT images combined with computational methods. This study proposes an innovative approach based on the generalization of models for pulmonary segmentation in CT images, using the Convolutional Neural Network Based on Mask Regions (Mask R-CNN) combined with image processing techniques, K-means clustering, region growing and Parzen window through fine-tuning. Our models achieved satisfactory results with 97% Accuracy and 98% Dice, 99% Sensitivity, and 97% Positive Predictive Value (PPV) in our best MPK model. The method was able to generalize its learning to solve different pulmonary segmentation problems in different lung CT databases. A second set of data was used, obtaining even better results. The results obtained for this second data set were: 98% Accuracy, 99% Dice, 100% Sensitivity, and 98% PPV, demonstrating the effectiveness of our method.
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