Necrotizing fasciitis is one of the rare reported pathological condition in oral and maxillofacial region. It is characterized by rapidly progressive necrosis of fascia, with involvement of skin and muscles in late stages and can be fatal. We report a case of necrotizing fasciitis of neck and part of face, who presented to our institute with chief complaint of swelling since 15 days. The fascitis was found odontogenic in origin with initially involvement of buccal, and masseteric spaces. The condition was further complicated as patient had diabetes mellitus that prolonged the healing, favoring the environment for bacterial growth and necrosis. Drainage of the involved spaces followed by subsequent debridement of wound and reconstruction with skin graft was done. This report is addition to existing literature elaborating the treatment of necrotizing fasciitis in patient with comorbidity, in stages. What one should do? When and how?
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