Ability Of Participants Research Articles

A plain language summary of the final analysis of the GRIFFIN study of daratumumab plus lenalidomide, bortezomib, and dexamethasone for people with newly diagnosed multiple myeloma.

This summary describes the final analysis of the GRIFFIN study. In this study, participants were newly diagnosed with a type of blood and bone marrow cancer called multiple myeloma, had never received any treatment, and were able to undergo an autologous stem cell transplant. The GRIFFIN study looked at adding the drug daratumumab (D) to a combination of standard treatments called RVd (lenalidomide [R], bortezomib [V], and dexamethasone [d]) during the treatment phases induction and consolidation, followed by daratumumab and lenalidomide (D-R) maintenance. Participants also received an autologous stem cell transplant to further help reduce multiple myeloma. The GRIFFIN study looked at whether D-RVd followed by D-R maintenance was better at killing multiple myeloma cells compared with RVd on its own followed by R maintenance on its own, and if treatments were safe. This summary also describes results from 2 other GRIFFIN publications: one that looked at participants with certain multiple myeloma characteristics or demographic factors that are associated with worse outcomes, and another that looked at how treatments impacted the participants' quality of life. At the time of the final analysis of GRIFFIN, participants who were treated with D-RVd followed by D-R maintenance had very low (undetectable) levels of multiple myeloma cells and multiple myeloma markers (biological signs) and were more likely to be alive without the multiple myeloma getting worse or coming back compared with participants who received standard RVd treatment followed by R maintenance. There was also a pattern of similar benefits achieved by participants who were at risk for worse outcomes. Additionally, participants who received D-RVd treatment followed by D-R maintenance reported less pain, less fatigue (extreme tiredness), and greater improvements in their ability to conduct daily physical activities. While some side effects (unwanted or unexpected effects of treatment) were higher with D-RVd, side effects in both groups were as expected, and adding daratumumab did not reduce a participant's ability to handle treatment. Results of the GRIFFIN study showed that D-RVd treatment followed by D-R maintenance was better at treating multiple myeloma than the standard treatment of RVd followed by R maintenance in adults with a new diagnosis of multiple myeloma who were able to receive an autologous stem cell transplant, with no unexpected side effects of treatment.Clinical Trial Registration: NCT02874742 (GRIFFIN) (ClinicalTrials.gov).

The effectiveness of perspective video modelling training on one‐stage word problem‐solving skills in children with autism spectrum disorder

AbstractSingle‐subject research can provide adequate justification when developing successful evidence‐based educational practices for children with autism spectrum disorder (ASD), which can help such students thrive academically. This research investigates whether point‐of‐view video modelling effectively improved the word problem‐solving addition performances of primary‐school‐aged students with ASD. The effectiveness of the intervention on each participant's ability to solve single‐digit addition by a single digit, effectively view the video on a tablet and generalise a learned skill was investigated by utilising a design that included several participant baselines. All participants saw an improvement in their ability to solve simple addition problems due to using point‐of‐view video modelling. Between the baseline and intervention phases, each participant's rate of digits correctly entered per minute and total number of steps completed significantly increased. A generalisation phase was performed at home. After receiving the intervention, people with ASD could independently complete word problems involving addition with a single digit. The findings suggest that this technology could practically support the education of the growing number of children and young people with ASD by mollifying the particular learning obstacles their impairment brings.

Enhanced multisensory gain in older adults may be a by-product of inverse effectiveness: Evidence from a speeded response-time task.

Older adults experience a greater benefit from multisensory integration than their younger counterparts, but it is unclear why. One hypothesis is that age-related sensory decline weakens unisensory stimulus effectiveness, causing a boost in multisensory gain through inverse effectiveness. Many previous studies present stimuli at the same intensity for both younger and older adults (i.e., stimulus-matched), as opposed to accounting for each participant's unique perceptual ability (i.e., perception-matched). This makes it difficult to discern the source of age-related differences in multisensory gain. As such, we used two experiments to examine whether sensory decline is contributing to age-related differences in multisensory gain. In the first, we presented auditory (pure tones in noise), visual (Gabor patches in noise), and audiovisual stimuli and recorded response times from 31 younger (18-25) and 30 older (55-80) adults. Importantly, all participants were given identical stimuli, with the expectation that older adults would show worse unisensory performance, inducing inverse effectiveness. The second task was identical (younger N = 31, older N = 34), except stimuli were presented at each participant's 50% detection threshold, identified with an adaptive psychophysical staircase, controlling for any influence of inverse effectiveness. Older adults were found to exhibit greater multisensory gain (as measured by race model violations) on stimulus- but not perception-matched tasks, thus aligning with the principle of inverse effectiveness. That is, when accounting for potential age-related differences in perceptual abilities, older adults no longer experienced greater benefit from multisensory integration. These two experiments together suggest that the age-related increases in multisensory integration previously reported may be in part due to age-related declines in vision and audition. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Gender bias of antisocial and borderline personality disorders among psychiatrists.

Antisocial Personality Disorder (ASPD) and Borderline Personality Disorder (BPD) challenge mental health professionals with similar maladaptive behaviors. However, these two disorders differ regarding available evidence-based treatments. The Diagnostic and Statistical Manual of Mental Disorders (DSM) has been criticized as being gender-biased diagnostic construct. The present study aimed to determine the gender bias of ASPD and BPD among Turkish psychiatrists. Three case vignettes were randomly presented as male or female to the psychiatrists online. The first case was a patient with schizophrenia case to confirm the participant's ability to diagnose. The second case was a patient with ASPD, and the third one was a patient with BPD. Two hundred fifty participants diagnosed the first case correctly (n = 250). The results with statistical significance demonstrated that a female case with ASPD was 5.1 times more likely to get misdiagnosed than a male case with ASPD (p˂0.0001). Categorical classification of personality disorders in DSM leads to gender bias in in the diagnosis of ASPD and BPD. The present study shows that female cases with ASPD are misdiagnosed as BPD which may result in treatment attempts without evidence.

An Exploratory Study of Large-Scale Brain Networks during Gambling Using SEEG.

Decision-making is a cognitive process involving working memory, executive function, and attention. However, the connectivity of large-scale brain networks during decision-making is not well understood. This is because gaining access to large-scale brain networks in humans is still a novel process. Here, we used SEEG (stereoelectroencephalography) to record neural activity from the default mode network (DMN), dorsal attention network (DAN), and frontoparietal network (FN) in ten humans while they performed a gambling task in the form of the card game, "War". By observing these networks during a decision-making period, we related the activity of and connectivity between these networks. In particular, we found that gamma band activity was directly related to a participant's ability to bet logically, deciding what betting amount would result in the highest monetary gain or lowest monetary loss throughout a session of the game. We also found connectivity between the DAN and the relation to a participant's performance. Specifically, participants with higher connectivity between and within these networks had higher earnings. Our preliminary findings suggest that connectivity and activity between these networks are essential during decision-making.

Visual Disruptions as Mnemonic Devices: Investigating the Efficacy of Environmental Anomalies in Memory Retrieval

Remembering information and experiences is what enables us to solve new problems that confront us in the future.The current study examines how visual disturbance or visual anomalies are effective in enhancing memory and helping to recall tasks that participants need to remember. Thus it aims to explore the effectiveness of visual anomalies in improving memory recall compared to traditional methods. The study relied on mixed method approach through a quantitative and qualitative data procedure. Twenty volunteers who did not suffer from psychological or mental disorders, aged from forty to fifty years, participated in this study. They were distributed into two groups, control and experimental. The control group relied on traditional ways to remember the tasks, while the experimental group used confusion and unusual visual anomalies as a means of remembering. The researcher tested the participant's ability to remember at intervals of 24, 48, and 72 hours and after a week. The results revealed the superiority of the experimental group over the control group in remembering the tasks assigned to them. In addition, the findings stress the effectiveness of using visual interference to enhance memory and remember things and that the visual disturbance is an effective signal to stimulate memory, especially if these interferences are distinctive and far from the usual, as they help attract the participant’s attention. Thus, this strategy is more effective than traditional methods, and the more distinct the visual noise is, the better and faster its effectiveness in enhancing memory. The research results indicate that adding this strategy to participants’ daily activities may be an effective and useful way to enhance memory. The Visual Disruption Mnemonics (VDM) framework encapsulates the core principles derived from the findings, offering a robust framework for understanding and applying this novel mnemonic strategy in various contexts.

Factors related to training time and achieving proficiency with visual-assistive mobile applications in visually impaired older adults.

A majority of visually impaired older adults were able to learn to proficiently use visual-assistive iPhone applications (apps) following a median 1 hour and/or multiple training sessions, which should be considered when planning vision rehabilitation service delivery, including the option for remote telerehabilitation for those who prefer that modality. Older adults with low vision are increasingly using technology to improve their visual functioning. We examined whether age-related comorbidities were potential barriers to success in learning to use visual-assistive apps on a smartphone. A clinical trial assessed visual-assistive apps in 116 older adults aged 55+ years (mean [standard deviation], 72 [10] years). Subjects were randomized to use an app (SuperVision+, Seeing AI, or Aira) preloaded to a loaner iPhone and completed one-on-one training. App proficiency was measured by the participant's ability to use the iPhone/app without cueing at the end of training sessions. Training time was recorded for the initial session and totaled after subsequent sessions. Multiple regression models explored significant factors associated with training time and proficiency. Median initial and total training times were 45 and 60 minutes, respectively. Increased initial and total training times were both significantly related to increased age (p<0.001), legal blindness (p<0.007), Seeing AI versus SuperVision+ app (p<0.03), and participants from New England versus California (p<0.001). Most (71%) achieved proficiency after the initial training session; those odds were significantly greater among younger participants (p=0.04), those who opted for telerehabilitation (p=0.03), those who had higher cognitive scores (p=0.04), or those who were from New England (p=0.04). The majority (90%) was ultimately proficient with the app; those odds were significantly greater among participants who already had an optical magnifier (p=0.008), but were unrelated to other factors including study site. Following multiple, extensive training sessions, age, mild cognitive loss, or level of visual impairment did not preclude gaining proficiency with visual-assistive apps by visually impaired seniors, but those factors were associated with longer training times. Telerehabilitation can be a viable option to provide app training remotely for visually impaired seniors who choose that modality.

Assessing nutrition literacy and nutrition counseling proficiency following an interdisciplinary culinary medicine elective.

Culinary medicine (CM) is a growing field of education that aims to bridge the gap between the clinical need for nutritional counseling and the lack of education on the topic. Healthcare professionals can aid in nutrition-related noncommunicable disease (NCD) prevention by improving a patient's dietary behavior. However, the presence of nutrition education in healthcare curricula is lacking. Early evidence indicates that CM could address this gap. The objectives of this study are to determine ifthe provision of an interdisciplinary CM elective will improve student knowledge and confidence with counseling on nutrition and culinary principles, and to improve personal dietary habits of students. This was a one-group pretest-posttest quasi-experimental design. First- and second-year osteopathic medical students (OMS) and nurse practitioner students were recruited to participate in a CM elective via email. Participants were excluded if they were not in good academic standing at their respective institutions. Twelve individuals (n=8 medical; n=4 nursing) were enrolled in the course. Participants completed pre- and postcourse surveys to determine changes in nutrition literacy (Nutrition Literacy Assessment Instrument [NLit42]), nutrition counseling proficiency (Nutrition Survey for Family Practitioners), and dietary quality (Automated Self-Administered 24-h dietary assessment tool; ASA24®). A two-sided, paired t test was conducted to determine changes in outcome variables. All 12 participants completed the precourse assessments, and 8 participants completed the postcourse assessments. Culinary activity attendance was 94.5 %. Participants exhibited a statistically significant increase in their overall nutrition literacy scores after completing the CM elective (p=0.006). Literacy subcategories indicated that the improvement came from the participant's ability to understand household measurements (p=0.005) better. Increases in self-reported proficiency were observed for participants' confidence to counsel on nutrition and prevention/wellness (p=0.02) and macronutrients in health and food safety (p=0.01). No statistically significant changes in the personal dietary pattern or quality were observed. The interdisciplinary CM elective improved nutrition literacy and some aspects of counseling proficiency. Although small shifts in dietary variables were observed, the elective did not statistically improve participants' dietary pattern. However, some changes that were observed may lead to clinically relevant outcomes if maintained long-term. These findings are encouraging. Implementing CM as an educational tool could improve healthcare practitioners' ability to understand and counsel patients on nutrition to prevent the nutrition-related NCDs.

Opportunity for a Community Health Fair Model of Bleeding Control Training.

Traumatic hemorrhage is a prevalent cause of death nationally, with >50% of civilian deaths estimated to be preventable with more timely intervention. This study investigated the efficacy of training large and diverse audiences in bleeding control methods including tourniquets in community health fair settings. A booth was utilized for bleeding control training at community health fairs via direct demonstrations of pressure, wound packing, and commercial and improvised tourniquet application followed by hands-on practice. Participants self-rated their perceived abilities while instructors rated the participant competency. 117 community members participated during two fairs, though not every person completed every portion of the training. Average age was 33 (range 6-82) and the majority were female (65.0%). There was no difference in self-perceived skill compared to trainer grading of participant's ability to identify life-threatening bleeding (112 (97.4%) vs 106 (97.2%); P = 1), apply pressure (113 (98.3%) vs 106 (97.2%); P = .68), and pack a wound (102 (88.7%) vs 92 (84.4%); P = .43). No difference in difficulty was noted in placing commercial vs improvised tourniquets (16 (43%) vs 14 (45%); P = .87). However, participants were overconfident in their ability to place tourniquets compared to trainer grading, respectively (112 (98.2%) vs 100 (91.7%; P = .03)). Community fair classes provide opportunities to train large and diverse audiences in bleeding control techniques. However, participants overestimated their ability to appropriately apply tourniquets. Further investigation is needed into best educational approaches to optimize the impact of bleeding control kits that have been distributed in multiple states.

실행증의 작업치료

Purpose: Apraxia is a target of occupational therapy because it negatively affects a person ability and independence in performing basic and instrumental activities of daily living and the person’s social participation. We aimed to provide comprehensive information related to apraxia to effectively provide occupational therapy for patients with apraxia. Subjects: Diagnosis of apraxia involves evaluation through clinical observation, such as the ability to pantomime, imitate, and complete multi-step tasks, and standardized evaluation tools, such as the Test of Upper Limb Apraxia (TULIA) and the Apraxia Screen of TULIA (AST). Evidence-based interventions for apraxia include gesture and strategy training. Although evidence is still lacking, interventions using virtual reality or mirrors are also being introduced to treat apraxia. Interventions based on functional cognition concepts can also be applied to the treatment of apraxia. Functional cognitive interventions include tasks/habits and strategies and indirect interventions. Conclusion: Apraxia can cause difficulties when attempting to perform intentional movements, thereby reducing a participant's ability to perform functional activities. Accordingly, implementing patient-centered occupational therapy tailored to the special needs of patients with apraxia is necessary. Findings of this study will be meaningful for the implementation of evidence-based occupational therapy for apraxia.

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method.

The combined single-breath measurement of the diffusing capacity of carbon monoxide (DL,CO) and nitric oxide (DL,NO) is a useful technique to measure pulmonary alveolar-capillary reserve in both healthy and patient populations. The measurement provides an estimate of the participant's ability to recruit and distend pulmonary capillaries. The method has recently been reported to exhibit a high test-retest reliability in healthy volunteers during exercise of light to moderate intensity. Of note, this technique permits up to 12 repeated maneuvers and only requires a single breath with a relatively short breath-hold time of 5 s. Representative data are provided showing the gradual changes in DL,NO and DL,CO from rest to exercise at increasing intensitiesof up to 60% of maximal workload. The measurement of diffusing capacity and evaluation of alveolar-capillary reserve is a useful tool to evaluate the lung's ability to respond to exercise both in the healthy population as well as in patient populations such as those with chronic lung disease.

Facilitation of motor adaptation using multiple gait rehabilitation interventions.

The rate of adjustment in a movement, driven by feedback error, is referred to as the adaptation rate, and the rate of recovery of a newly adapted movement to its unperturbed condition is called the de-adaptation rate. The rates of adaptation and de-adaptation are dependent on the training mechanism and intrinsic factors such as the participant's sensorimotor abilities. This study investigated the facilitation of the motor adaptation and de-adaptation processes for spatiotemporal features of an asymmetric gait pattern by sequentially applying split-belt treadmill (SBT) and asymmetric rhythmic auditory cueing (ARAC). Two sessions tested the individual gait characteristics of SBT and ARAC, and the remaining four sessions consisted of applying the two interventions sequentially during training. The adjustment process to the second intervention is referred to as "re-adaptation" and is driven by feedback error associated with the second intervention. Ten healthy individuals participated in the randomized six-session trial. Spatiotemporal asymmetries during the adaptation and post-adaptation (when intervention is removed) stages were fitted into a two-component exponential model that reflects the explicit and implicit adaptation processes. A double component was shown to fit better than a single-component model. The decay constants of the model were indicative of the corresponding timescales and compared between trials. Results revealed that the explicit (fast) component of adaptation to ARAC was reduced for step length and step time when applied after SBT. Contrarily, the explicit component of adaptation to SBT was increased when it was applied after ARAC for step length. Additionally, the implicit (slow) component of adaptation to SBT was inhibited when applied incongruently after ARAC for step time. These outcomes show that the role of working motor memory as a translational tool between different gait interventions is dependent on (i) the adaptation mechanisms associated with the interventions, (ii) the targeted motor outcome of the interventions; the effects of factors (i) and (ii) are specific to the explicit and implicit components of the adaptation processes; these effects are unique to spatial and temporal gait characteristics.

Correlation of fatigue on walking ability in myasthenia gravis patients: a cross-sectional study.

Myasthenia gravis (MG) is a neuromuscular junction autoimmune disease characterised of intermittent muscle weakness that increases with activity and recovers with rest. Analysing the correlation of fatigue on walking ability in MG patients. This study used a cross-sectional design with consecutive sampling. Participants MG patients took in this trial. Data collection encompasses fatigue and walking ability, with fatigue being assessed using the fatigue severity scale (FSS) and walking ability being assessed using the 10-metre walking test. The 10-metre walking test assessment contains three components: comfortable walking speed (CWS), maximum walking speed (MWS), and natural cadence. The statistical analysis used in this study includes the Pearson correlation and Spearman rank tests with P<0.05. The number of participants was 23 MG patients, and most of the participant was female (69.6%). The participant's fatigue value was 5.46±1.13, including MGFA 1=5.32±1.15, MGFA 2A=5.5±1.11, and MGFA 2B=5.61±1.30. Meanwhile, the participant's walking abilities included CWS of 1.10±0.11m/s, MWS of 1.31±0.15m/s, and natural cadence of 110.91±7.74 steps/min. No significant correlation of fatigue on walking ability including FSS vs. CWS (r=-0.141; P=0.520), FSS vs MWS (r=-0.169; P=0.442), and FSS vs. natural cadence (r=-0.050; P=0.822). There was no significant correlation between fatigue and walking ability in MG patients who had MGFA 1, MGFA 2A, and MGFA 2B.

ADDRESSING DIVERSITY AND INCLUSIVITY IN SOUNDSCAPE RESEARCH, DEVELOPING METHODOLOGIES FOR UNDER- AND NON-REPRESENTED PARTICIPANTS

Soundscape research has often struggled to deal with multidimensional phenomenological perception of the sound environment. When teaching sound related studies and conducting soundscape research, often little or no consideration is given to addressing the diversity of participants taking part in the class or study. For example, there is often no consideration made of a participant's hearing ability, with many of the standard methods and practices emphasising and assuming ‘normal’ hearing. There have been some studies with consideration of hearing impairment, but aural diversity is not all about impairment, diversity of unimpaired listeners can often be related to ‘quite basic mechanisms like pitch detection’ (DAVIES 2019). The consideration of diversity in soundscape research creates a further epistemological problem of perception. This paper discusses the author’s experience from their practice based research to start addressing the issues of inclusivity and diversity, suggesting how the creative industries can adapt existing methods and be at the forefront of new methods including gamification, social data collection and analysis, implementation of VR and AR in community studies, along with the consideration of adapting soundwalking into ‘soundsitting’, which can both raise awareness of the sound environment and obtain phenomenologically rich empirical data from inclusive and diverse under- and non-represented participants.

Pelatihan Penggunaan Aplikasi Mendeley Sebagai Manajemen Referensi Bagi Mahasiswa Teknologi Pengecoran Logam Polman Ceper Untuk Bekal Magang Kerja dan Penulisan Tugas Akhir

Students must be able to manage citations from various scientific journals and books in the final semester. Citation management is vital in writing internship reports, final assignments and journals. However, most students still need help citing and writing a bibliography. Therefore, this PKM activity aims to train students to use the Mendeley application to cite and write a bibliography automatically. There are two stages of training: the explanation or demonstration stage and the practice stage. The presenter accompanies the training participants in practising the use of Mendeley. The improvement in participants' skills was measured using a questionnaire method. The participant's ability to operate Mendeley has increased, as evidenced by the average pre-test score of 51.57 and post-test of 79.57. The training evaluation results showed that 71.4% of participants stated that the quality of the material presented was excellent and could equip students to write scientific papers.

Training to Improve Spatial Hearing andSituation Awareness when Wearing Hearing Protection.

Hearing protection devices (HPDs) are standard personal protective equipment in military settings, but many service members may choose to not use HPDs because they impair spatial hearing and situation awareness. In an effort to reduce barriers to compliance by improving situation awareness while wearing HPDs, this study investigated whether brief training could counteract spatial hearing deficits when wearing HPDs. Participant's ability to correctly apply the HPDs across days was also examined. Young adults were randomly assigned to one of two groups: training or control (n = 25/group). Participants in each group performed a spatial hearing task while wearing HPDs and in an open ear condition without HPDs. Individual targets were battlefield sounds or white noise presented from a speaker array that surrounded the participant in the horizontal plane. After presentation of each target sound, the participant then controlled a white noise "auditory pointer," which they moved to the perceived location of the target. The two primary measures were the percent of trials with very large errors (> 45°), which were usually due to confusing front and back locations, and absolute localization, which is the difference between the pointer location and the true sound location. Both groups were tested on Days 1 (baseline) and 5 (post-test). On Days 2 to 4, the training group wore HPDs while receiving auditory and visual feedback after each trial. Across all participants on Day 1, wearing HPDs increased the frequency of very large errors by about 3× and impaired localization by about 40%, relative to the open ear condition. When comparing performance at baseline (Day 1) and post-training Day 5, the training group with HPDs had significant reductions in very large errors and improved absolute localization (P values < .001). The training group also had significant improvements from Days 1 to 5 in the open ear condition. When the control group wore HPDs, there were also significant improvements from Days 1 to 5 (fewer very large errors and better localization), with smaller effect sizes vs. the training group. Controls did not have significant improvement in the open ear condition, but had similar trends. Most participants consistently applied the HPDs, but a subset of ∼20% frequently failed to achieve the criterion attenuation of 15 dB (over 0.25-4.0 kHz) in both ears. These findings show that simple, relatively brief practice and training can substantially reduce HPD impairments on spatial hearing and situation awareness. The gains from training and practice can inform the development of relatively simple, brief methods to reduce HPD spatial hearing impairments, potentially leading to increased HPD compliance. Longitudinal data show that a subset of participants would not have received the full benefit of hearing protection because of improper application of the HPDs.

Pelatihan Komputer dan Penggunaan Microsoft Word Pada Siswa Berkebutuhan Khusus Di Homeschooling Lantaburo Kabupaten Tangerang

Homeschooling (HS) Lantaburo is one of the alternative schools in the city of Tangerang which has a target of fostering and developing life skills for Students with Special Needs (ABK) so they can meet the basic needs of Activity of Daily Living (ADL) so that one day they can be independent and empowered in society. In implementing the ADL program, there are obstacles, namely the difficulty of keeping up with advances in computer technology as a medium for supporting the learning of ABK students. Based on these problems, this community service aims to introduce ABK students to operating computers and teach them how to use Microsoft Word features that can be used to learn typing and others. The method used is hands-on training on basic introduction to computers and Microsoft Word applications. Of the 26 students with special needs at HS Lantaburo who were given the opportunity by the teacher to take part in the training, there were 3 students namely Autism, Dyslexia, and Down Syndrome (DS) due to limited computer equipment and training time. The context of the training is based on the participant's ability to answer every question posed in the training, starting from managing text, fonts, data storage, etc. Meanwhile, making tables still requires frequent practice. The results of the training were that Autism and Dyslexia student participants had the same range of intelligence so they could follow the training well compared to DS participants. This can be seen from the results of the evaluation carried out after the training activities. ABK students can improve their ability to operate computer equipment and Microsoft Word software, including the ability to type, edit, and format documents. Increase motivation to study, more confidence and independent in operating computers and MS Word applications.

PELATIHAN PENGELOLAAN MENAJEMEN KEUANGAN PADA UMKM PUSPA PINUNJUL

Abstract &#x0D; There are still many MSME actors who face obstacles in managing administration and financial management which have an impact on difficulties in obtaining access to capital and also in managing financial management. Community service is carried out to 1) To raise awareness and put the responsibilities of MSME actors/entrepreneurs regarding the importance of managing finances properly so that it will be easier to evaluate the development of their business, (2) To equip the abilities and skills of UMKM Puspa Pinunjul actors, (3) so that they can use and implementing a simple financial management system that is easily implemented in groups so that it can improve the financial performance of business units, (4) To increase the Participant's ability to make budget plans so that they can maintain the business and can develop the business in accordance with the plan according to the purpose of establishing a business. Community service activities are carried out at the UMKM Puspa Pinunjul in Klumutan Village, Saradan District, Madiun Regency. The implementation method goes through 4 stages which include Coordination and division of team work, shared perceptions with partners, implementation of workshops and Evaluation. Participants consisted of 17 namely the chairman and members who were members of UMKM Puspa Pinunjul. The results obtained from community service are an increase in understanding related to financial management and a positive response to the usefulness of implementing activities.&#x0D; Keywords : Financial management, Training, SMEs, Business Units

NZ-RugbyHealth Study: Current Postural Control Ability of Former Rugby Union and Non-contact Sport Players.

Players in contact sports frequently experience mild traumatic brain (concussion) injuries (TBI). While there are known disruptions to balance following acute head trauma, it is uncertain if sport-related concussion injuries have a lasting impact on postural control. To assess postural control in retired rugby players in comparison to retired non-contact sport players, and to evaluate any association with self-reported sport-related concussion history. Using a cross-sectional design, 75 players in the NZ-RugbyHealth study from three sports groups (44 ± 8years; 24 elite rugby, 30 community rugby, 21 non-contact sport) took part in this study. The SMART EquiTest® Balance Master was used to assess participant's ability to make effective use of visual, vestibular and proprioceptive information using standardised tests. Postural sway was also quantified using centre of pressure (COP) path length. The relationship among sports group, sport-related concussion history and postural control was evaluated using mixed regression models while controlling for age and body mass index. Limited significant differences in balance metrics were found between the sports groups. A statistically significant (p < 0.001) interaction indicated a relationship between COP path length and sport-related concussion history in the most challenging balance condition, such that path length increased as the number of previous sport-related concussions increased. There was some evidence for a relationship between sport-related concussion recurrence in sports players and postural stability in challenging balance conditions. There was no evidence of impaired balance ability in retired rugby players compared with non-contact sport athletes.

Effect of a dedicated PI-QUAL curriculum on the assessment of prostate MRI quality

PurposeThe Prostate Imaging Quality (PI-QUAL) score is a metric to evaluate the diagnostic quality of multiparametric magnetic resonance imaging (MRI) of the prostate. This study evaluated the impact of a prostate MRI quality training lecture on the participant's ability to assess prostate MRI image quality. MethodsEighteen in-training-radiologists of varying experience in reviewing diagnostic prostate MRI assessed the image quality of ten examinations. Then, they attended a dedicated lecture on MRI quality assessment using the PI-QUAL score. After the lecture, the same participants evaluated the image quality of a new set of ten scans applying the PI-QUAL score. Results were assessed using receiver operating characteristic (ROC) analysis. The reference standard was the PI-QUAL score assessed by a fellowship trained abdominal radiologist with experience in reading prostate MRI. ResultsThere was a significant improvement in the average area under the curve (AUC) for assessment of prostate MRI image quality from baseline (0.82; [0.576 – 0.888]) to post teaching (1.0; [0.954–1]), with an improvement of 0.18 (p < 0.03). When ROC curves were computed for different cohorts stratified based on year of training, difference ranged from 0.48 for second year residents to 0.32 for fourth year residents (p < 0.001–0.01). For abdominal imaging fellows, the pre-teaching AUC was 0.9 [0.557–1] and post teaching AUC was 1 [0.957–1], a difference of 0.1 (p = 0.20). ConclusionsA dedicated lecture on PI-QUAL improved the ability of radiologists-in-training to assess prostate MRI image quality, with variable impact depending on year of training.