Body Parts Research Articles

Drug-Coated Central Venous Catheters – A Comprehensive Review of Strategies in the Development to Overcome Biofilm Formation and Related Infections

Central venous catheters (CVCs) are implantable medical instruments regularly used in intense care units for the easy introduction of medical drugs and medicaments, to give fluids intravenously, nutriments, transfusion of blood and also to withdraw blood samples. Bloodstream infections associated with the usage of catheters are the most recurrent, harmful as well as expensive impediment. This is the omnipresent reason for the introduction of bacteria and related infections. Among the various types of medical devices, the rate of infection, morbidity and mortality are higher with the usage of CVCs than any other types of medical instruments. Biofilm developed due to contamination by microorganisms. The biofilm is a bunch of microorganisms accumulated on the surface of CVCs. These biofilms contribute to the proliferation of microbes and increase antimicrobial resistance against antibiotics, affect the host’s immunity and get spread to the various body parts. Numerous approaches have been evolved to overcome the above mentioned issues associated with the usage of CVCs. In the said review, the authors have summarized the usage of CVCs, biofilm formation, development of infection, strategies and innovations in the modification of CVCs aiming to avoid the CRBSI and subsequent resistance to antimicrobial drugs.

Formulation and Evaluation of Soap Containing Extracts of Various Ethnomedicines

The herbal soap’s formulation includes neem leaf; all herbal ingredients are easily obtained from the local herbal market. Use of cosmetics is part of caring for the skin and other body parts due to the damaging effects of modern pollution and UV rays on human health; aloe plants produce a material used in cosmetic goods to treat burns, psoriasis, acne, and other skin disorders; preparation of herbal soap is a medication or therapy with therapeutic benefits for the skin, including antibacterial and antifungal qualities; the raw material used to make soap has a number of properties that make it a good medicinal or cosmetic. The plant used to manufacture soap has properties that can help eliminate acne, soften the skin’s epidermis, increase penetration, and hasten healing and resolution. Natural remedies like aloe vera are used to both prevent and cure a range of skin conditions. The medicinal properties of aloe vera soap include antiseptic, antimicrobial, antiviral, antioxidant, and antifungal properties. The aloe vera plant features tubular yellow blossoms, many-seeded fruits, and triangular, fleshy leaves with serrated edges. Each leaf consists of three layers: an inner, transparent gel that contains 99% water and glucomannans, amino acids, lipids, sterols, and vitamins in the remaining 2%. The intermediate layer of latex is composed of a bitter-yellow sap. Neem provides additional medicinal benefits. Studies have demonstrated the anti-inflammatory, anti-hyperglycemic, anti-ulcer, antimalarial, antifungal, antibacterial, antimutagenic, and anticarcinogenic properties of neem and its chemical components. Tulsi provides many skin-benefiting qualities, such as beep-clean skin. Turmeric and vitamin C are also used to help tone the skin when treating breakouts. Homegrown cleaning solutions with medicinal or sedative qualities, such as antimicrobial and antifungal qualities, can benefit the skin. The rough material used in the cleanser formulation has multiple prescription drugs or cosmetics attached to it. The plant used in cleanser formulations has the ability to smooth out skin imperfections, enhance skin texture, prevent breakouts, and hasten healing and resolution.

Understanding Epidemiological Trends in Geriatric Burn Injuries: A National Multicenter Analysis from NEISS 2004-2022.

Burn injuries pose a significant source of patient morbidity/mortality and reconstructive challenges for burn surgeons, especially in vulnerable populations such as geriatric patients. Our study aims to provide new insights into burn epidemiology by analyzing the largest national, multicenter sample of geriatric patients to date. Utilizing the National Electronic Injury and Surveillance System (NEISS) database (2004-2022), individuals with a "Burn" diagnosis were extracted and divided into two comparison age groups of 18-64 and 65+. Variables including sex, race, affected body part, incident location, burn etiology, and clinical outcomes were assessed between the two groups utilizing two proportion z-tests. 60,581 adult patients who sustained burns were identified from the NEISS database with 6,630 of those patients categorized as geriatric (65+). Geriatric patients had a significantly greater frequency of scald burns (36.9% vs. 35.4%; p<0.01), and third degree/full-thickness burns (10.4% vs 5.5%, p<0.01) relative to non-geriatric adult patients with most of these burns occurring at home (75.9% vs 67.4%; p<0.01). The top five burn sites for geriatric patients were the hand, face, foot, lower arm, and lower leg and the top five burn injury sources were hot water, cookware, oven/ranges, home fires, and gasoline. Geriatric patients had over two times greater risk of hospital admission (OR: 2.32, 95% CI: 2.17-2.49, p<0.01) and over five times greater risk of ED mortality (OR: 6.22, 95% CI: 4.00-9.66, p<0.01) after incurring burn injuries. These results highlight the need for stronger awareness of preventative measures for geriatric burn injuries.

The body interior in anorexia nervosa: from interoception to conceptual representation of body interior.

Body image disorders are well documented in anorexia nervosa (AN); however, knowledge of interoceptive awareness (IA) in this population remains poor. This descriptive study investigated whether and how the representation of the interior of the body may have an impact on IA. The representations and knowledge of the body interior were evaluated with a drawing task in 34 women with AN and 34 healthy controls (HCs). A lexicometric analysis was performed on the vocabulary used to describe the drawn body parts in a structured interview. It was assumed that the conceptual representation of the body interior could be affected by or influence IA. Thus, the relationship between IA, measured with the heartbeat task and the ischemia-induction test, and the drawings was explored. Other scales, such as those of body shape, awareness or satisfaction, were used to assess affective representations of the body. The drawing, lexicometric and IA results were similar in the two groups. No correlations were found among IA, body representation scores and representation level of body interior. Only the representation of bones by the AN group was significantly different. Increased visual attention to the skeleton or greater awareness of bone health could explain the stronger representation of bones in the AN group. The psychophysical therapy received by some AN participants (73%) did not seem to have influenced IA. Our results do not support a relationship between IA and the representation of the body interior.Clinical trial registration:https://clinicaltrials.gov/, identifier NCT03988218.

The geometry of interpersonal synchrony in human dance

Collective synchronized behavior has powerful social-communicative functions observed across several animal taxa.1,2,3,4,5,6,7 Operationally, synchronized behavior can be explained by individuals responding to shared external cues (e.g., light, sound, or food) as well as by inter-individual adaptation.3,8,9,10,11 We contrasted these accounts in the context of a universal human practice-collective dance-by recording full-body kinematics from dyads of laypersons freely dancing to music in a "silent disco" setting. We orthogonally manipulated musical input (whether participants were dancing to the same, synchronous music) and visual contact (whether participants could see their dancing partner). Using a data-driven method, we decomposed full-body kinematics of 70 participants into 15 principal movement patterns, reminiscent of common dance moves, explaining over 95% of kinematic variance. We find that both music and partners drive synchrony, but through distinct dance moves. This leads to distinct kinds of synchrony that occur in parallel by virtue of a geometric organization: anteroposterior movements such as head bobs synchronize through music, while hand gestures and full-body lateral movements synchronize through visual contact. One specific dance move-vertical bounce-emerged as a supramodal pacesetter of coordination, synchronizing through both music and visual contact, and at the pace of the musical beat. These findings reveal that synchrony in human dance is independently supported by shared musical input and inter-individual adaptation. The independence between these drivers of synchrony hinges on a geometric organization, enabling dancers to synchronize to music and partners simultaneously by allocating distinct synchronies to distinct spatial axes and body parts.

Scavenger-induced scattering of wild boar carcasses over large distances and its implications for disease management

Vertebrate scavengers provide essential ecosystem services such as accelerating carrion decomposition by consuming carcasses, exposing tissues to microbial and invertebrate decomposers, and recycling nutrients back into the ecosystem. Some scavengers do not consume carcasses on site but rather scatter their remains in the surroundings, which might have important implications for nutrient transport, forensic investigations and the spread of diseases such as African Swine Fever. However, only a few studies have investigated and measured the scatter distances. Using wild boar (Sus scrofa) carcasses and limbs, we monitored scavenging behavior and measured scatter distances of mammals. We placed 20 carcasses (up to 25 kg) and 21 separate limbs equipped with very high frequency (VHF) transmitters and monitored scavenger activity using camera traps in a mountainous region in southeast Germany. Except for one carcass, all other carcasses and limbs were scattered. We measured 72 scatter distances (of 89 scattering events; mean = 232 m, maximum = 1250 m), of which 75% were dispersed up to 407 m. Scavengers moved scattered pieces into denser vegetation compared to the half-open vegetation at provisioning sites. Red foxes (Vulpes vulpes) were the most common scavenger species, contributing to 72 scattering events (58 measured scatter distances). Our results provide evidence of scatter distances farther than previously assumed and have far-reaching implications for disease management or forensic investigations, as the broader surroundings of carcasses must be included in search efforts to remove infectious material or relevant body parts for forensic analysis.

Preparation of CNT/CNF/PDMS/TPU Nanofiber-Based Conductive Films Based on Centrifugal Spinning Method for Strain Sensors.

Flexible conductive films are a key component of strain sensors, and their performance directly affects the overall quality of the sensor. However, existing flexible conductive films struggle to maintain high conductivity while simultaneously ensuring excellent flexibility, hydrophobicity, and corrosion resistance, thereby limiting their use in harsh environments. In this paper, a novel method is proposed to fabricate flexible conductive films via centrifugal spinning to generate thermoplastic polyurethane (TPU) nanofiber substrates by employing carbon nanotubes (CNTs) and carbon nanofibers (CNFs) as conductive fillers. These fillers are anchored to the nanofibers through ultrasonic dispersion and impregnation techniques and subsequently modified with polydimethylsiloxane (PDMS). This study focuses on the effect of different ratios of CNTs to CNFs on the film properties. Research demonstrated that at a 1:1 ratio of CNTs to CNFs, with TPU at a 20% concentration and PDMS solution at 2 wt%, the conductive films crafted from these blended fillers exhibited outstanding performance, characterized by electrical conductivity (31.4 S/m), elongation at break (217.5%), and tensile cycling stability (800 cycles at 20% strain). Furthermore, the nanofiber-based conductive films were tested by attaching them to various human body parts. The tests demonstrated that these films effectively respond to motion changes at the wrist, elbow joints, and chest cavity, underscoring their potential as core components in strain sensors.

First insights into the spatial behaviour of Octopus vulgaris in the wild using acoustic telemetry

Octopuses are amongst the most fascinating animals in our oceans; however, while their intricate behaviours are often studied in laboratory settings, basic aspects of their movement ecology remain unstudied in the wild. Focusing on the socio-economically important common octopus (Octopus vulgaris), this study employs, for the first time, acoustic tracking techniques to address knowledge gaps regarding the species spatial ecology within a marine protected area. A total of 24 wild O. vulgaris (13 males, 11 females) were tagged in 2022 in the National Park Maritime-Terrestrial of the Atlantic Islands of Galicia, Spain. Acoustic transmitters were externally attached to the third arm, after testing other body parts (mantle cavity). Males were on average detected on 10 times more occasions than females (49 days in males and five in females). The average activity space in the study area was large in comparison to that determined in similar studies, with 0.16 km2. Activity space between males and females as well as day and night were comparable. Tagged octopuses displayed a crepuscular activity pattern. The location of dens could be established for 15 out of 24 individuals, from which octopuses were observed to undertake regular daytime excursions. Several individuals were also found to occupy more than one den and/or switch their main dens throughout the study duration. First implications and benefits of this approach are discussed.

Targeted drug release from stable and safe ultrasound-sensitive nanocarriers.

Targeted delivery of medication has the promise of increasing the effectiveness and safety of current systemic drug treatments. Focused ultrasound is emerging as noninvasive and practical energy for targeted drug release. However, it has yet to be determined which nanocarriers and ultrasound parameters can provide both effective and safe release. Perfluorocarbon nanodroplets have the potential to achieve these goals, but current approaches have either been effective or safe, but not both. We found that nanocarriers with highly stable perfluorocarbon cores mediate effective drug release so long as they are activated by ultrasound of sufficiently low frequency. We demonstrate a favorable safety profile of this formulation in a non-human primate. To facilitate translation of this approach into humans, we provide an optimized method for manufacturing the nanocarriers. This study provides a recipe and release parameters for effective and safe drug release from nanoparticle carriers in the body part specified by focused ultrasonic waves.

Critical review on physiological aspects of Samana Vata

Background: Samana Vata which is located near the seat of Agni and it have role in digestion as well as in the assimilation of ingested food. Anna Grahana, Pachana, Vivechana and Munchan are the functions of Samana Vata. The physiological functions of Samana Vata can be correlated with enteric nervous system which is known as the second brain, and parasympathetic and sympathetic supply of autonomic nervous system. ENS functions by maintaining the enteric homeostasis and also act as modulator in gut barrier functions. After the food reaches stomach, several digestive juice acts on it. Gastric juice, pancreatic juice, all contains important digestive enzymes and act on food. Secretion of this enzyme is mostly under the control of intrinsic and extrinsic enteric nervous system. Aims and Objective: To critically analyse the concept of Samana Vata and find out the correlation with modern physiology. Materials and Methods: Literature review was referred from different classical text books and relevant modern textbooks, articles, data bases like google scholar, pubmed. Conclusion: Samana Vata chiefly locates in the middle part of body. It is primarily responsible for stimulation of Agni and leads to digestion, absorption, separation of essence and waste material. Function of Samana Vata, described by Acharyas can be compared with the physiological function of enteric nervous system. It can be partially correlated with enteric nervous system, sympathetic and parasympathetic supply of autonomic nervous system.

Three-stage Dynamic Brain-cognitive Model of Understanding Action Intention Displayed by Human Body Movements.

The ability to comprehend the intention conveyed through human body movements is crucial for effective interpersonal interactions. If people can't understand the intention behind other individuals' isolated or interactive actions, their actions will become meaningless. Psychologists have investigated the cognitive processes and neural representations involved in understanding action intention, yet a cohesive theoretical explanation remains elusive. Hence, we mainly review existing literature related to neural correlates of action intention, and primarily propose a putative Three-stage Dynamic Brain-cognitive Model of understanding action intention, which involves body perception, action identification and intention understanding. Specifically, at the first stage, body parts/shapes are processed by those brain regions such as extrastriate and fusiform body areas; During the second stage, differentiating observed actions relies on configuring relationships between body parts, facilitated by the activation of the Mirror Neuron System; The last stage involves identifying various intention categories, utilizing the Mentalizing System for recruitment, and different activation patterns concerning the nature of the intentions participants dealing with. Finally, we delves into the clinical practice, like intervention training based on a theoretical model for individuals with autism spectrum disorders who encounter difficulties in interpersonal communication.

Confidence sharing adaptation for out-of-domain human pose and shape estimation

3D human pose and shape estimation is often impacted by distribution bias in real-world scenarios due to factors such as bone length, camera parameters, background, and occlusion. To address this issue, we propose the Confidence Sharing Adaptation (CSA) algorithm, which corrects model bias using unlabeled images from the test domain before testing. However, the lack of annotation constraints in the adaptive training process poses a significant challenge, making it susceptible to model collapse. CSA utilizes a decoupled dual-branch learning framework to provide pseudo-labels and remove noise samples based on the confidence scores of the inference results. By sharing the most confident prior knowledge between the dual-branch networks, CSA effectively mitigates distribution bias. CSA is also remarkably adaptable to severely occluded scenes, thanks to two auxiliary techniques: a self-attentive parametric regressor that ensures robustness to occlusion of local body parts and a rendered surface texture loss that regulates the relationship between occlusion of human joint positions. Evaluation results show that CSA successfully adapts to scenarios beyond the training domain and achieves state-of-the-art performance on both occlusion-specific and general benchmarks. Code and pre-trained models are available for research at https://github.com/bodymapper/csa.git

Pornography in The Perspective of Islamic and National Law

This research aims to explain the perspective of Islamic and national law on pornography. This is a normative juridical research with a comparative approach which is analyzed by prescriptive analysis. The results of the research show that Islamic and national law have the same paradigm towards pornography as a despicable act which is prohibited by sharia and the constitution. There are at least two terms in Islamic law that have intersections with pornography; first, the term aurat, which is a part of the human body that should not be shown or must be covered because it can cause shame (QS.24: 58) and arouse the sexual desires of others who see it (QS.33: 59). Secondly, tabarruj, which describes a person in a dress that tends to be indecent or characterizes the appearance of a dishonorable person. Meanwhile, national law regulates this pornography in several regulations such as Law No. 44/2008 on Pornography; several articles in the Criminal Code; Law No. 32/2002 on Broadcasting; Law No. 8/1992 on Film; Law No. 40/1999 on Press; Law No. 36/1999 on Telecommunications; and Law No.11/2008 on Information and Electronic Transactions.

Pornography in The Perspective of Islamic and National Law

This research aims to explain the perspective of Islamic and national law on pornography. This is a normative juridical research with a comparative approach which is analyzed by prescriptive analysis. The results of the research show that Islamic and national law have the same paradigm towards pornography as a despicable act which is prohibited by sharia and the constitution. There are at least two terms in Islamic law that have intersections with pornography; first, the term aurat, which is a part of the human body that should not be shown or must be covered because it can cause shame (QS.24: 58) and arouse the sexual desires of others who see it (QS.33: 59). Secondly, tabarruj, which describes a person in a dress that tends to be indecent or characterizes the appearance of a dishonorable person. Meanwhile, national law regulates this pornography in several regulations such as Law No. 44/2008 on Pornography; several articles in the Criminal Code; Law No. 32/2002 on Broadcasting; Law No. 8/1992 on Film; Law No. 40/1999 on Press; Law No. 36/1999 on Telecommunications; and Law No.11/2008 on Information and Electronic Transactions.

Visuo-spatial complexity potentiates the body-part effect in intransitive imitation of meaningless gestures.

Recent studies on the imitation of intransitive gestures suggest that the body part effect relies mainly upon the direct route of the dual-route model through a visuo-transformation mechanism. Here, we test the visuo-constructive hypothesis which posits that the visual complexity may directly potentiate the body part effect for meaningless gestures. We predicted that the difference between imitation of hand and finger gestures would increase with the visuo-spatial complexity of gestures. Second, we aimed to identify some of the visuo-spatial predictors of meaningless finger imitation skills. Thirty-eight participants underwent an imitation task containing three distinct set of gestures, that is, meaningful gestures, meaningless gestures with low visual complexity, and meaningless gestures with higher visual complexity than the first set of meaningless gestures. Our results were in general agreement with the visuo-constructive hypothesis, showing an increase in the difference between hand and finger gestures, but only for meaningless gestures with higher visuo-spatial complexity. Regression analyses confirm that imitation accuracy decreases with resource-demanding visuo-spatial factors. Taken together, our results suggest that the body part effect is highly dependent on the visuo-spatial characteristics of the gestures.

Managing Fear Responses: A Qualitative Analysis of Pictorial Warning Labels Five Years Post-Plain Packaging.

Although pictorial warning labels (PWLs) now dominate tobacco packages sold in many countries, few studies have probed how people who smoke respond to the threats presented several years post-plain packaging and larger PWLs. Understanding how people manage the fear and dissonance PWLs arouse, and the strategies they use to rationalize, diminish, and reject risk messages, could inform future PWL design. We undertook 27 in-depth interviews with people aged 18 and over (16 female, 8 Māori, and 13 aged ≤35) who smoked roll-your-own tobacco and lived in Aotearoa New Zealand. We probed participants' views on current PWLs and how they responded to these, then asked them to use alternative images and headlines to create new PWLs. We drew on the extended parallel processing model to interpret the data, which we analyzed using a reflexive thematic analysis approach. People who smoke dislike PWLs, which they think reduce them to diseased body parts. While a minority thought existing PWLs were believable and effective, most reported avoiding PWLs by hiding or cognitively blocking them. Participants used diverse counterarguments to diminish PWLs' relevance and impact, and a minority displayed strong reactance. Several suggested developing PWLs that recognized them as whole people rather than patients in waiting, and recommended greater use of testimonials, particularly from people who had successfully become smoke free. PWLs using more holistic and diverse messages could elicit greater engagement and responsiveness, and motivate cessation more effectively than existing health-oriented warnings. Our findings suggest existing PWLs, which aim to arouse fear of ill health, could be complemented by warnings that emphasize the benefits of quitting. Continuing to use threat-based PWLs could stimulate greater rationalization and reactance. By contrast, PWLs that aim to illustrate how cessation could benefit people who smoke and their families, rather than instill a fear of disease, could avoid message rejection and counter-argument, and may prove a more powerful way of motivating cessation.

Selective activations and functional connectivities to the sight of faces, scenes, body parts and tools in visual and non-visual cortical regions leading to the human hippocampus

Connectivity maps are now available for the 360 cortical regions in the Human Connectome Project Multimodal Parcellation atlas. Here we add function to these maps by measuring selective fMRI activations and functional connectivity increases to stationary visual stimuli of faces, scenes, body parts and tools from 956 HCP participants. Faces activate regions in the ventrolateral visual cortical stream (FFC), in the superior temporal sulcus (STS) visual stream for face and head motion; and inferior parietal visual (PGi) and somatosensory (PF) regions. Scenes activate ventromedial visual stream VMV and PHA regions in the parahippocampal scene area; medial (7m) and lateral parietal (PGp) regions; and the reward-related medial orbitofrontal cortex. Body parts activate the inferior temporal cortex object regions (TE1p, TE2p); but also visual motion regions (MT, MST, FST); and the inferior parietal visual (PGi, PGs) and somatosensory (PF) regions; and the unpleasant-related lateral orbitofrontal cortex. Tools activate an intermediate ventral stream area (VMV3, VVC, PHA3); visual motion regions (FST); somatosensory (1, 2); and auditory (A4, A5) cortical regions. The findings add function to cortical connectivity maps; and show how stationary visual stimuli activate other cortical regions related to their associations, including visual motion, somatosensory, auditory, semantic, and orbitofrontal cortex value-related, regions.

Minimally destructive hDNA extraction method for retrospective genetics of pinned historical Lepidoptera specimens

The millions of specimens stored in entomological collections provide a unique opportunity to study historical insect diversity. Current technologies allow to sequence entire genomes of historical specimens and estimate past genetic diversity of present-day endangered species, advancing our understanding of anthropogenic impact on genetic diversity and enabling the implementation of conservation strategies. A limiting challenge is the extraction of historical DNA (hDNA) of adequate quality for sequencing platforms. We tested four hDNA extraction protocols on five body parts of pinned false heath fritillary butterflies, Melitaea diamina, aiming to minimise specimen damage, preserve their scientific value to the collections, and maximise DNA quality and yield for whole-genome re-sequencing. We developed a very effective approach that successfully recovers hDNA appropriate for short-read sequencing from a single leg of pinned specimens using silica-based DNA extraction columns and an extraction buffer that includes SDS, Tris, Proteinase K, EDTA, NaCl, PTB, and DTT. We observed substantial variation in the ratio of nuclear to mitochondrial DNA in extractions from different tissues, indicating that optimal tissue choice depends on project aims and anticipated downstream analyses. We found that sufficient DNA for whole genome re-sequencing can reliably be extracted from a single leg, opening the possibility to monitor changes in genetic diversity maintaining the scientific value of specimens while supporting current and future conservation strategies.

Descending networks transform command signals into population motor control

To convert intentions into actions, movement instructions must pass from the brain to downstream motor circuits through descending neurons (DNs). These include small sets of command-like neurons that are sufficient to drive behaviours1—the circuit mechanisms for which remain unclear. Here we show that command-like DNs in Drosophila directly recruit networks of additional DNs to orchestrate behaviours that require the active control of numerous body parts. Specifically, we found that command-like DNs previously thought to drive behaviours alone2–4 in fact co-activate larger populations of DNs. Connectome analyses and experimental manipulations revealed that this functional recruitment can be explained by direct excitatory connections between command-like DNs and networks of interconnected DNs in the brain. Descending population recruitment is necessary for behavioural control: DNs with many downstream descending partners require network co-activation to drive complete behaviours and drive only simple stereotyped movements in their absence. These DN networks reside within behaviour-specific clusters that inhibit one another. These results support a mechanism for command-like descending control in which behaviours are generated through the recruitment of increasingly large DN networks that compose behaviours by combining multiple motor subroutines.

Three-Dimensional Discrete Element Analysis of Bearing Characteristics of Concrete–Cored Sand–Gravel Pile Composite Foundation under Cyclic Dynamic Load

Concrete-cored sand–gravel piles are a kind of composite pile formed by wrapping a concrete-cored pile with a sand–gravel shell, which has the advantages of both a rigid pile and bulk-material pile. The bearing characteristics of the concrete-cored sand–gravel pile composite foundation were investigated by establishing a three-dimensional discrete element numerical model for a cyclic dynamic loading test. The results show that the vertical stress of the core pile body fluctuates greatly at the beginning of loading, and the fluctuation amplitude decreases with the depth, and gradually tends to be stable in the middle and late stages, and the vertical-stress distribution is relatively uniform. The radial stress in the upper part of the core pile body fluctuates greatly, the fluctuation in the lower part is small, and the radial stress in each part of the core pile body gradually tends to be stable in the late-loading period. The radial stress factor of the core pile body reaches the stable speed with the foundation depth decreasing; the fluctuation amplitude of the pile-soil stress ratio decreases with the foundation depth and gradually tends to be stable with the increase in loading. The results of this study can provide a reference for the design and construction of a core sand pile composite foundation.