Parity States Research Articles

The Danish national haemoglobinopathy screening programme: Report from 16 years of screening in a low-prevalence, non-endemic region.

The Danish national haemoglobinopathy screening programme seeks to determine parental haemoglobinopathy carrier state antenatally. In this retrospective register-based study, we evaluated the 16-year trajectory of this programme, utilising the Danish Red Blood Cell Centre's laboratory database, covering approximately 77% of the Danish population. During the study period, we observed a substantial increase in annual diagnostic examinations performed, from 389 in 2007 to 3030 in 2022. Women constituted 88% of these cases, aligning with the emphasis of the screening programme. Of these, 54% of women of reproductive age (15-40 years) and 10% of women >40 years were specified as pregnant. During our study period, 61 children were born with a severe haemoglobinopathy, out of which 23 children were born from mothers not residing in Denmark during their first trimester thus not included in the screening programme. Prenatal invasive testing was performed for 60 fetuses, identifying 12 with homozygous or compound heterozygous haemoglobinopathy. The Danish haemoglobinopathy screening programme has provided screening, information and reproductive choices for numerous families. During the study period, screening for haemoglobinopathies has been steadily increasing and is expected to continue to increase. Awareness of and adherence to the screening programme is subject of further investigation and optimisation.

Controllable shaping of CV–DV entanglement between CV states of certain parity and delocalized photon

Controllable shaping of CV–DV entanglement between CV states of certain parity and delocalized photon

Photon strength functions from (p,γ) reactions

The 50Cr(p,γ)51Mn proton capture reaction has been used to study the photon strength functions by utilizing primary gamma ray transitions from the entry states to discrete states of known spins and parities. The reaction was conducted with the 3 MV Tandetron accelerator at iThemba LABS which delivered proton beams of 2.5 to 2.740, 2.760 to 3.0 MeV and 3.675 to 4.498 MeV in intervals of 20-25 keV with beam currents of up to 5 μA. In this work the proton capture reaction was employed together with the Average Resonance Capture method to extract the shape of the PSF of 51Mn.

Joint survey of the experimental high-resolution spectra of H16O37Cl and H16O35Cl with a reanalysis of the [formula omitted] band

The study starts with a detailed analysis of all the high-resolution rovibrational transitions measured for the minor hypochlorous acid isotopologue H16O37Cl, employing the Marvel (Measured Active Rotational-Vibrational Energy Levels) procedure. The survey considers 16 sources, the wavenumber coverage of the transitions extends from the microwave to the visible region, corresponding to 13 vibrational parent states. Experimental transitions data from older (1994, 1996, and 2000) sources, not published explicitly in the original papers, are presented in here for the first time; the newly reported transitions represent about one third of all the transitions assigned for H16O37Cl. Then a minor update to the transitions and levels of H16O35Cl published in J. Mol. Spectrosc. 384 (2022) 111561 is provided. Proper labelling and internal consistency of the transitions and the empirical rovibrational energies of H16O35Cl and H16O37Cl is enforced utilizing effective Hamiltonian (EH) and first-principles variational nuclear-motion computation results. An iteratively updated line list, based on empirical and EH rovibrational energy levels and first-principles intensities, is used to assign a significant number of new transitions in the 2ν2 band (2300–2800 cm−1) for both isotopologues. At the end, for H16O35Cl/H16O37Cl, from the total of 20349/10266 experimentally measured transitions considered, 20119/10124 could be validated, allowing the derivation of 5760/3933 empirical rovibrational energy levels with well-defined uncertainties. Improved parameters for an effective Hamiltonian corresponding to the 2ν2 state are given. A comparison with data in the canonical spectroscopic line-by-line database HITRAN is also provided.

Impact of state telehealth policies on telehealth use among patients with newly diagnosed cancer.

Telehealth restrictions were relaxed under the COVID-19 public health emergency. We examined telehealth use before and during the pandemic among patients with newly diagnosed cancers and the association between state policies and telehealth use. The study cohort was constructed from Optum's deidentified Clinformatics Data Mart and included patients with lymphoma, female breast cancer, colorectal cancer, prostate cancer, and lung cancer diagnosed between March 1, 2019, and March 31, 2021. We performed an interrupted time series analysis to examine the trend of cancer-related telehealth use within 1 month of diagnosis relative to the timing of the COVID-19 public health emergency and multivariable logistic regressions to examine factors-specifically, state parity laws and regulations on cross-state practice-associated with telehealth. Of 110 461 patients, the rate of telehealth use peaked at 33.4% in April 2020, then decreased to 12% to 15% between September 2020 and March 2021. Among the 53 982 patients diagnosed since March 2020, telehealth use was statistically significantly lower for privately insured patients residing in states with coverage-only parity or no or unspecified parity than those in states with coverage and payment parity (adjusted rate = 20.2%, 19.1%, and 23.3%, respectively). The adjusted rate was lower for patients in states with cross-state telehealth policy limitations than for those in states without restrictions (14.9% vs 17.8%). Telehealth use by patients diagnosed with cancer during the pandemic was higher among those living in states with more generous parity and less restrictive rules for cross-state practice. Policy makers contemplating whether to permanently relax certain telehealth policies must consider the impact on vulnerable patient populations who can benefit from telehealth.

Predictors of parental anxiety in a paediatric emergency department

BackgroundChildren experience significant anxiety in the paediatric ED. Although research from preoperative and primary care samples indicates that parents experience anxiety surrounding their children’s medical procedures, less is known about...

Schmidt decomposition of parity adapted coherent states for symmetric multi-quDits

In this paper we study the entanglement in symmetric N-quDit systems. In particular we use generalizations to U(D) of spin U(2) coherent states (CSs) and their projections on definite parity (multicomponent Schrödinger cat) states and we analyse their reduced density matrices when tracing out M < N quDits. The eigenvalues (or Schmidt coefficients) of these reduced density matrices are completely characterized, allowing to prove a theorem for the decomposition of a N-quDit Schrödinger cat state with a given parity into a sum over all possible parities of tensor products of Schrödinger cat states of N − M and M particles. Diverse asymptotic properties of the Schmidt eigenvalues are studied and, in particular, for the (rescaled) double thermodynamic limit ( fixed), we reproduce and generalize to quDits known results for photon loss of parity adapted CSs of the harmonic oscillator, thus providing an unified Schmidt decomposition for both multi-quDits and (multi-mode) photons. These results allow to determine the entanglement properties of these states and also their decoherence properties under quDit loss, where we demonstrate the robustness of these states.

Federalization, Land-for-Peace or a War Once More: Secession Conflicts in Post-Soviet Countries

Abstract This essay conceptualizes five recipes to solve secession conflicts that have taken place in postcommunist territories—federalization, land-for-peace, protectorate policy, reconquest, and the destruction of the parent state by the patron state—and investigates their merits and demerits. This essay provides case studies of the South Ossetian War in 2008 and its aftermath (as an example of the protectorate policy), the Second Karabakh War in 2020 (reconquest), and the Russo-Ukrainian War in 2022 (destruction of the parent state by the patron state). We observe the tendency that the ineffectiveness of federalization and land-for-peace induces parties of conflict to move on to unilateral or even coercive recipes.

The value of parental medical records for the prediction of diabetes and cardiovascular disease: a novel method for generating and incorporating family histories.

To determine whether data-driven family histories (DDFH) derived from linked EHRs of patients and their parents can improve prediction of patients' 10-year risk of diabetes and atherosclerotic cardiovascular disease (ASCVD). A retrospective cohort study using data from Israel's largest healthcare organization. A random sample of 200000 subjects aged 40-60years on the index date (January 1, 2010) was included. Subjects with insufficient history (<1year) or insufficient follow-up (<10years) were excluded. Two separate XGBoost models were developed-1 for diabetes and 1 for ASCVD-to predict the 10-year risk for each outcome based on data available prior to the index date of January 1, 2010. Overall, the study included 110734 subject-father-mother triplets. There were 22153 cases of diabetes (20%) and 11715 cases of ASCVD (10.6%). The addition of parental information significantly improved prediction of diabetes risk (P < .001), but not ASCVD risk. For both outcomes, maternal medical history was more predictive than paternal medical history. A binary variable summarizing parental disease state delivered similar predictive results to the full parental EHR. The increasing availability of EHRs for multiple family generations makes DDFH possible and can assist in delivering more personalized and precise medicine to patients. Consent frameworks must be established to enable sharing of information across generations, and the results suggest that sharing the full records may not be necessary. DDFH can address limitations of patient self-reported family history, and it improves clinical predictions for some conditions, but not for all, and particularly among younger adults.

Honeycomb Sb layers on Cu(111) and parities of the surface states

The performed DFT study of the electronic structure of honeycomb Sb monolayer adsorbed on the Cu(111) surface has confirmed previous observations of significant role of tensile strain and related reduced buckling of adsorbed layer. The simulated STM pictures are perfectly consistent with those observed in experiment. We show that a significant band mixing with the substrate, which leads to an absence of occupied surface states at M point, questions applicability of the method of determination of the topological invariant Z2 by means of estimates of the products of the parity eigenvalues. Hence, since the adsorption interaction with a metal surface is rather strong, the transformations of the bands of free honeycomb Sb layers with increasing lattice constants, which was recently suggested to cause the transition to the topological insulator state for certain range of the tensile strain, do not directly correspond to the changes which occur for adsorbed layers.

Validity of Brink-Axel Hypothesis for calculations of allowed stellar weak rates of heavy nuclei

The knowledge of beta-decay transitional probabilities and Gamow-Teller (GT) strength functions from highly excited states of nuclides is of particular importance for applications to astrophysical network calculations of nucleosynthesis in explosive stellar events. These quantities are challenging to achieve from measurements or computations using various nuclear models. Due to unavailability of feasible alternatives, many theoretical studies often rely on the Brink-Axel (BA) hypothesis, that is, the response of strength functions depends merely on the transition energy of the parent nuclear ground state and is independent of the underlying details of the parent state, for the calculation of stellar rates. BA hypothesis has been used in many applications from nuclear structure determination to nucleosynthesis yield in the astrophysical matter. We explore here the the validity of BA hypothesis in the calculation of stellar beta-decay (BD) and electron capture (EC) weak rates of fp- and fpg-shell nuclides for GT transitions. Strength functions have been computed employing the fully microscopic proton-neutron QRPA (quasi-particle random-phase approximation) within a broad density, ρY e = (10-1011) [g cm−3], and temperature, T = (1−30) [GK], grid relevant to the pre-collapse astrophysical environment. Our work provides evidence that the use of the approximation based on the BA hypothesis does not lead to reliable calculations of excited states strength functions under extreme temperature-density conditions characteristic of presupernova and supernova evolution of massive stars. Weak rates obtained by incorporating the BA hypothesis in the calculation of strength functions substantially deviate from the rates based on the state-by-state microscopically calculated strength functions. Deviation in the two calculations becomes significant as early as neon burning phases of massive stars. The deviation in the calculation of BD rates is even more pronounced, reaching up to three orders of magnitude.

Multi-dimensional influence of pediatric epilepsy on children and their families: A cross-sectional study

ObjectiveIn this study, we aimed to evaluate the effects of pediatric epilepsy on family burden, parental anxiety, depression states, and quality of life of both parents and children. MethodsThe study was undertaken between March and December 2021 using an online questionnaire that included the Family Burden Scale of Disease, the 7-item Generalized Anxiety Disorder scale, the 9-item Patient Health Questionnaire, the WHO Quality of Life Scale (WHOQOL-BREF), and the PedsQL 4.0 Generic Core Scales (parent-proxy report). ResultsA total of 288 parents of children aged 2–18 years were included. Overall, 94.8% of the participating families experienced high levels of disease burden, 67.0% of parents suffered from anxiety states, 57.0% suffered from depression states, and 56.2% of children with epilepsy suffered from comorbid neuropsychiatric symptoms. The mean WHOQOL-BREF score for parental quality of life was 53.7 ± 12.8, while the median PedsQL score for children's quality of life was 65.4 (49.6–81.7). Parental depression states contributed the most to family burden and parental quality of life, whereas comorbidities of epilepsy contributed the most to children's quality of life. Seizure frequency significantly influenced parental anxiety states, and family burden was the most significant predictor of parental depression states. ConclusionHeavy disease burden, anxiety states, and depression states are prevalent in families with children suffering from epilepsy, and most have a poor quality of life. There is a need for greater focus on the quality of life of this patient population and their caregivers, as well as increased resources to help combat anxiety, depression, and poor quality of life.

Parental socialization of guilt and shame in early childhood

Self-conscious emotions emerge early in human development and they help children navigate social relationships. Little is known about the socialization of self-conscious emotions in early childhood. We theorized that parental mental state language use and warmth would be important for young children’s self-conscious emotions and their consequent prosocial behaviors. Ninety-eight children residing in the Netherlands (52% girls) aged 2–5 (M = 48.66 months, SD = 13.50 months) visited the research lab with one parent. First, we observed parental mental state language and warmth. Afterward, children were led to believe that they caused a mishap (i.e., accidentally breaking the experimenter’s favorite toy) to evoke their guilt and shame, which we micro-coded. In subsequent tasks, we observed children’s helping behaviors toward the experimenter. We found that the combination of frequent parental mental state language and high warmth was associated with children’s quicker helping to the previously harmed experimenter across toddlerhood and early childhood. More guilt was related to more helping whereas more shame-like avoidance was related to less helping. Our findings based on the sample of Dutch parents and children suggest that, parental frequent mental state talk, in combination with high warmth, may promote children’s ability to repair social relationships and behave prosocially after mishaps.

Impact of Private Payer Policies on the Transition to Telemental Health Care Among Privately Insured Patients with Mental Health Disorders.

Introduction: Mental health patients in states without private payer telehealth reimbursement policies before the public health emergency (PHE) may have experienced reduced access to telemental health (TMH). We estimate the association between private payer telehealth policy status in 2019 and the transition to TMH in 2020. Methods: Retrospective cohort study of privately insured individuals 2-64 years old with a mental health disorder and without TMH use in 2019. We examined new telemental use in 2020 by three categories of policy reimbursement status in 2019 (partial parity, full parity vs. no policy), overall (any telemental), and by modality (live video, audio-only, and online assessments) using logistic regression models clustered by state. Results: Among the 34,612 enrollees, 54.7% received TMH for the first time. Relative to no policy states, enrollees in partial or full parity states were equally likely to receive TMH in 2020. However, enrollees in states with a private payer telehealth policy were less likely to receive audio-only (partial parity: odds ratio [OR]: 0.59, 95% confidence interval [CI]: 0.39-0.90; full parity: OR: 0.38, 95% CI: 0.26-0.55), but more likely to receive online assessments (full parity: OR: 2.28, 95% CI: 1.4-4.59). Conclusions: Privately insured enrollees similarly transitioned to TMH across states suggesting a broad impact of the PHE policies on access to this care. The differences in audio-only and online assessments suggest that providers were possibly better prepared to implement TMH care via live video or patient portals in states with telehealth policies.

Stationary broken parity states in active matter models.

We demonstrate that several nonvariational continuum models commonly used to describe active matter as well as other active systems exhibit nongeneric behavior: each model supports asymmetric but stationary localized states even in the absence of pinning at heterogeneities. Moreover, such states only begin to drift following a drift-transcritical bifurcation as the activity increases. Asymmetric stationary states should only exist in variational systems, i.e., in models with gradient structure. In other words, such states are expected in passive systems, but not in active systems where the gradient structure of the model is broken by activity. We identify a "spurious" gradient dynamics structure of these models that is responsible for this nongeneric behavior, and determine the types of additional terms that render the models generic, i.e., with asymmetric states that appear via drift-pitchfork bifurcations and are generically moving. We provide detailed illustrations of our results using numerical continuation of resting and steadily drifting states in both generic and nongeneric cases.

Dynamical parity selection in superconducting weak links

Excess quasiparticles play a crucial role in superconducting quantum devices ranging from qubits to quantum sensors. In this work we analyze their dynamics for phase-biased finite-length weak links with several Andreev subgap states, where the coupling to a microwave resonator allows for parity state (even/odd) readout. Our theory shows that almost perfect dynamical polarization in a given parity sector is achievable by applying a microwave pulse matching a transition in the opposite parity sector. Our results qualitatively explain key features of recent experiments on hybrid semiconducting nanowire Josephson junctions and provide theoretical guidelines for efficiently controlling the parity state of Andreev qubits.

Electroexcitation Form Factors and Deformation of 20,22Ne Isotopes Based on the Shell Model and Hartree-Fock plus BCS Calculations

Nuclear structure of 20,22Ne isotopes has been studied via the shell model with Skyrme-Hartree-Fock calculations. In particular, the transitions to the low-lying positive and negative parity excited states have been investigated within three shell model spaces; sd for positive parity states, spsdpf large-basis (no-core), and zbme model spaces for negative parity states. Excitation energies, reduced transition probabilities, and elastic and inelastic form factors were estimated and compared to the available experimental data. Skyrme interaction was used to generate a one-body potential in the Hartree-Fock calculations for each selected excited states, which is then used to calculate the single-particle matrix elements. Skyrme interaction was used to calculate the radial wave functions of the single-particle matrix elements, from which a one-body potential in Hartree-Fock theory with SLy4 parametrization can be generated. Furthermore, we have explored the interplays among neutron and proton density profiles in two dimensions, along with the deformations of 20,22Ne using Hartree-Fock plus BCS calculations.

Parental perceptions and experiences of care in the surgical neonatal intensive care unit

BackgroundParents endure significant stress when their newborns require surgery while in the neonatal intensive care unit (NICU). Our study aims to explore the surgical NICU experience from the parents’ perspective and identify areas that may improve this experience. A secondary objective was to integrate their feedback to refine the implementation strategy of the neonatal enhanced recovery after surgery (ERAS®) guideline.MethodsIn December 2019, five surgical NICU parents participated in a focus group. Conversation surrounded parents’ perspectives and experiences of the surgical NICU. Inductive analysis was performed to identify data, themes, and concepts that emerged from the discussion.ResultsParticipants identified four major interrelated themes that impacted the surgical parents’ NICU experience. These themes include (1) parental state, both physical and emotional, (2) the altered parental caregiver role which necessitates identifying alternative meaningful parental experiences, (3) the care team dynamic, incorporating consistency and effective communication, and (4) the discharge process which may be significantly eased through graduated, hands-on training.ConclusionKey elements of the neonatal ERAS® guideline address major themes and stressors identified by parents. The parental perspective may help clinicians appreciate the parent surgical NICU experience and assist in improving family-centered care to surgical infants and their families.

Study of positive parity states form factors for 17O nucleus with Skyrme-Hartree-Fock method

Study of positive parity states form factors for 17O nucleus with Skyrme-Hartree-Fock method

Occupancy of orbitals and the quadrupole collectivity in 45Sc nucleus.

In the present work, the Doppler Shift Attenuation method (DSAM) was used to analyze the observed lineshapes of transitions from excited states in 45Sc, populated in the reaction 36Ar + 12C at a beam energy of 145 MeV. The interpretation and comparison of the experimental results have been performed with large-scale shell model calculations, involving different interactions like: GX1A, GX1J, FPD6, KB3 and ZBM2. KB3 and FPD6 (present work) interactions in the negative parity states, and in positive parity states ZBM2 are most pre-eminent in reproducing the results, due to the large configuration space describing strong collective effects. Furthermore, the present work also looks at the details of the shell model helping in improving the understanding for the occupancy of orbitals. The present investigation suggests the observation of stronger collectivity for positive parity states over negative parity states with predicted enhanced collectivity of states in 45Sc nucleus.