REPORTS of tumors arising in various locations from the cells of the sympathetic nervous system, with variations in terms and classifications, have appeared in the literature from time to time since Wright (1), in 1910, first recognized the neurogenic nature of these neoplasms and applied the term neuroblastoma to them. They are also commonly referred to as sympathetico-blastoma and neurocytoma. Two different tumor types have been described. Those cases limited to the abdomen with metastases to the liver from an original site in the adrenal have been called the Pepper type. The cases presenting diffuse metastases to the skull, orbit, and long bones, and not limited to the abdomen, have been called the Hutchison type. Numerous reports subsequent to the original descriptions by Pepper (2) and by Hutchison (3) show such a classification to be without foundation, and that diffuse metastases to the bones and glands may occur in all cases. This paper is presented to add two cases of sympathetic neuroblastoma of cervical sympathetic origin to the literature. The roentgen data associated with them were of particular interest from both the diagnostic and therapeutic viewpoints, justifying a detailed discussion of the findings. Sympathetic neuroblastomas are found most commonly in infants and young children but also appear in adults, and occur with about equal frequency in both sexes. Increased recognition of these tumors in various locations has shown that they may arise from the cells of the sympathetic nervous system without special predilection for site. Scott, Oliver, and Oliver (4) tabulate a total of 162 reported cases arising in the medulla of the adrenal glands. Scott and Palmer (5) suggest a classification based on descriptive names, following the lines of embryologic development, and tabulate the reported cases arising from the sympathetic trunk exclusive of those arising within the medulla of the adrenal glands. The cervical sympathetic trunk is given as the original site of the tumor in but four of the 37 cases that are listed by them. The others have their origin in various parts such as the abdominal sympathetic”, thoracic sympathetic, coccygeal glald, celiac ganglion, mesentery, jejunum, liver, uterus, cavity of the nose, skin, paravertebral region, spinal canal (extradural), and the scapular region. The gross appearance of the tumor varies somewhat with the location, and presents itself as a soft hemorrhagic mass. The cut surface has a white or gray appearance, with necrosis and localized hemorrhagic areas. When it occurs in the adrenals there is destruction of the medulla with involvement of the cortex. Secondary metastatic nodules resembling the original tumor appear in the regional lymph glands, liver, and other tissues, including the bones.