With the recent rapid development of manufacturing techniques and material science, advanced hot-rolling of ultra-high strength steel (UHSS) with material grades up to S890 becomes possible. The structural behaviour of S890 hot-rolled ultra-high strength steel (UHSS) seamless circular hollow section (CHS) beam–columns fabricated through the advanced manufacturing method, was investigated through testing and numerical modelling and reported in this paper. In the physical testing, a total of 12 beam–columns were firstly tested featuring the flexural buckling failure mode, with the material coupon tests and initial global geometric imperfection measurements performed. FE modelling was then conducted, where the FE models were developed and validated against the test observations. The validated FE models were then adopted in the parametric studies in a wider spectrum of member lengths, cross-section dimensions and loading combinations, resulting in the additional 300 FE data to be generated. Finally, the current design provisions, as set out in Eurocode, American specification and Australian standard, are assessed for their applicability to S890 hot-rolled UHSS seamless CHS beam–columns. It was revealed from the assessment results that the design provisions in three design codes can be accurately applied to S890 hot-rolled UHSS seamless CHS beam–columns.