AbstractA machine learning-based method predicts the luminance decay of micro light emitting diode (micro-LED) displays, utilizing temperature distribution and degradation experiments alongside implementation on field-programmable gate array (FPGA). Micro-LEDs, used in outdoor and indoor billboards, experience degradation due to harsh environmental conditions. To model temperature distribution in indoor advertising displays using minimal data, a temperature model is constructed based on sensor from the panel and thermal images captured by a camera, in relation to the display pattern. The input data is processed using an FPGA, which transmits the sensed temperatures and display patterns to the micro-LED panel. Multilayer Perceptron (MLP), a type of neural network, predicts the temperature distribution over the panel surface, achieving an error of less than 1.1 °C. Separate degradation models forecast luminance decay, factoring in enclosure temperature, input current, and usage time, with distinct models for red, green, and blue LEDs. Exponential curve-fitting and interpolation, following TM-21 standards, ensure long-term accuracy. The luminance decay predictions have an average error below 1.05% (approximately 9 nits). The FPGA implementation minimizes resource consumption while maintaining prediction accuracy, making it suitable for real-time applications. The degradation model accurately predicts performance over tens or even hundreds of thousands of hours, aligning with the exponential decay trends defined by TM-21.