In this work, a new analysis of the isotopic composition of boron nuclei (B) in galactic cosmic rays (GCR) in the range of rigidities of 1–5 GV (nuclear energies 0.1–1.5 GeV/nucleon) was carried out using data from the PAMELA space experiment 2006–2014 on the rigidity of detected nuclei and their velocity (time-of-flight analysis and ionization losses in the instrument’s multilayer calorimeter). The new results of the PAMELA experiment expand the energy range of previous measurements, are consistent with the few existing data, and indicate deviations of the B isotope ratios from the GALPROP simulation data for the GCR, similar to the deviations for the Li and Be isotopes in the PAMELA data, which can be interpreted as evidence of observation against the background of the GCR the contribution of several local sources from explosions of nearby (hundreds of parsec) supernovae.