Modern industrial society is characterized by the growing threat of accidents and catastrophes caused by the human factor. This is a very broad concept. It includes many aspects of human interaction with the technogenic environment, including the probability of operator errors caused by the instability of his psychophysiological state, which is incompatible with the strict technological regulations. At the shift work, this instability is often caused by disturbances in the physiological rhythm of sleep — wakefulness followed by a biological conflict between the forced activity and certain phases of the natural circadian rhythm in the cognitive structures of the brain. This situation known for thy night shift modes can also occur in the evening shift modes. However, the influence of the «day — evening» mode on the psychophysiological state of the shift workers is studied to a lesser extent. The objective of this study was to identify the dynamics of the psychophysiological state of the employees of a certain «model» collective of the paint and varnish shop of the automobile plant, working in the shift mode «5 days — 2 days off — 5 evenings». Test persons were tested immediately after the 1st, 3rd and 5th shifts using a questionnaire describing their self-assessment ranked in points according to four categories (scales). Mathematical analysis of the results revealed a weak trend towards a decrease in the psychological indicators during the daytime work week, but a strong and statistically significant decrease in the evening shifts in relation to the daytime. Thus, the investigated rotational mode of work causes an increasing deterioration in the employee state in the evening shifts, which creates a risk of the impact of the psychogenic human factor on the occupational safety.