Objective To observe the antiemetic effect of azasetron plus low-dose dexamethasone in patients undergoing painless abortion surgery.Methods 270 ASA physical status Ⅰ~Ⅱpatients scheduled for elective painless abortion surgery were randomly divided into 3 equal groups.Patients intravenously received saline(group A),azasetron(group B),azasetron plus low-dose dexamethasone(group C)respectively.Anesthesia was induced with propofol(3 mg/kg)in combination with fentanyl(0.6μg/kg).Patients were interviewed after 24 hours of the surgery by telephone.The incidence of postoperative nausea and vomiting was recorded.Results The overall incidence of POVA in group B and C were significantly lower than group A.There was no significant difference between group B and C.Conclusion Azasetron in combination with low-dose dexamethasone produced same antiemetic effect as azasetron alone in patients underwent painless abortion surgery. Key words: Azasetron; Propofol; Dexamethasone; Nausea; Vomit
Read full abstract