Objective To compare the security between the sevoflurane anesthesia via laryngeal mask airway (LMA) composited nerve block in groin area and ketamine anesthesia in the pediatric hemioplasty. Methods 80 children (aged 2-6, weight 10-25kg, ASAⅠ-Ⅱ) with high ligation of hernia sac were divided into two groups according to the random number table method: group S-sevoflurane combined with inguinal region block under laryngeal airway ventilation; group K-ketamine combined with caudal block.Group S was inhalated with 6%-8% sevoflurane for foundation anesthesia, and then followed with vein induction: fentanyl 2μg/kg and propofol 2mg/kg.The laryngeal mask was placed when the temporomandibular joint was relaxed.Inguinal region was blocked by the surgeon after disinfect and spread towels.Anesthesia was maintained by 3% to 4% sevoflurane with mechanical ventilation interoperation.Group K was adopted the intramuscular ketamine (5mg/kg) for basic anesthesia and then used modified sacral canal blocking.Ketamine 1mg/kg was administered before skin incision.Additional ketamine 0.5mg/kg was intravenously injected when it was appeared with body move, choking cough, etc.The values of MAP and HR in the two groups were recorded respectively at the time point of 1min before skin cutting (T0), 1min after skin cutting (T1), 5min after skin cutting (T2), the end of operation (T3) and awaken time (T4). The body movement was observed intraoperation, the number of SpO2≤95% and awaken restlessness, the recovery time and residence time in anesthesia recovery room were recorded. Results The values of MAP in group S at time points of T1, T2, T3 were (77.6±6.2)mmHg, (77.8±6.4)mmHg, (76.5±4.7)mmHg respectively, and the values of MAP in group K at time points of T1, T2, T3 were (86.9±8.1)mmHg, (88.1±5.3)mmHg, (86.4±6.5)mmHg respectively.The t values at time points of T1, T2, T3 were 5.766, 7.893, 7.806 respectively when the group S compared with group K(P<0.0001), the group S was superior to group K. The values of HR in group S at time points of T1, T2, T3 were (121.3±9.6)times/min, (121.9±8.4)times/min, (120.3±7.8)times/min respectively, and the values of HR in group K at time points of T1, T2, T3 were (138.6±9.4)times/min, (136.5±7.5)times/min, (128.7±6.9)times/min respectively.The t values at time points of T1, T2, T3 were 8.144, 8.200, 5.101 respectively(P<0.0001), the group S was superior to group K. The MAP and HR were more smoothly in group S than in group K. The recovery time in group S and K was (7.5±3.4)min and (16.7±5.5)min respectively(t=8.99, P<0.0001), it was shorter in group S than in group K. The residence time in anesthesia recovery room was (15.4±4.2)min and (23.7±6.3)min respectively(t=6.93, P<0.0001), it was shorter in group S than in group K. Intraoperative body movements was 3 cases and 15 cases respectively in group S and group K(χ2=10.32, P<0.001); Cases of SpO2≤95% was 4 and 12 respectively in group S and group K(χ2=10.32, P<0.001), the occurrence of body movements and SpO2≤95% cases was lower in group S than in group K. Conclusion The sevoflurane anesthesia via LMA composited nerve block in groin area has the advantages of faster induction, faster recovery, the hemodynamics was more stable, adverse reactions was fewer and so on, it can be safely used in pediatric anesthesia. Key words: Laryngeal mask airway; Sevoflurane; Ketamine block in groin area; Pediatric hernia surgery
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