Abstract Previous studies indicate observed influences of autumn and winter Tibetan Plateau (TP) snow-cover anomalies on the winter Pacific–North American (PNA) teleconnection. This study simulates atmospheric and oceanic responses to persistent autumn–winter TP snow forcing using an atmospheric general circulation model (AGCM) and a coupled atmospheric-oceanic general circulation model (AOGCM), and quantifies the role of atmosphere–ocean interactions over North Pacific in TP snow effects. The AOGCM experiment induces a stronger and more realistic remote PNA response to heavy TP snow anomalies, and also a significant winter horseshoe-like North Pacific sea surface temperature (SST) pattern resulting from an anomalous equivalent barotropic cyclone, or a strengthened Aleutian low, with associated cyclonic wind stress anomalies. The horseshoe-like SST anomaly pattern is used as boundary forcing (without prescribed heavy TP snow) in another AOGCM experiment, which simulates an enhanced winter Aleutian low and a PNA-like response similar to the original AOGCM responses, indicating that that the direct Pacific–North American atmospheric response to persistent TP snow forcing in the AGCM is amplified in the AOGCM by the North Pacific midlatitude atmosphere–ocean interactions. This suggests that the mechanisms of the winter PNA responses to TP snow forcing involve dynamical atmospheric processes such as horizontal propagation of Rossby wave energy and transient eddy feedbacks, and also North Pacific atmosphere–ocean interactions, which provide a positive feedback on the development of the remote PNA teleconnection. Significance Statement The Tibetan Plateau has a 2.5 million km2 area and a 4000 m average elevation, and is often called “the third pole” because of its polar-like climate in midlatitude Eurasia. A heavy Tibetan Plateau snow cover increases the albedo effect and causes tropospheric cold temperature and low height changes that can be carried or advected to the North Pacific by the prevailing westerlies. The purpose of this study is to better understand how Tibetan Plateau snow anomalies influence the North Pacific and the remote atmospheric circulation through numerical simulations. Our results find that those North Pacific responses amply the direct atmospheric response to Tibetan Plateau snow-cover anomalies. This greatly improves our understanding of physical mechanisms of Tibetan Plateau snow impacts.