This paper studied gasoline vapor combustion catalyzed by Pd/Al2O3 in oxygen-poor condition. By adjusting the gasoline vapor and oxygen, the inlet temperature and flow rate, collecting data of temperature difference between outlet and inlet as well as the change of gas mixture, the study analyzed the various factors in the catalytic combustion process, and optimized the process control parameters. The results indicated that catalytic combustion was more efficient at the ignition temperature of 274 °C, burned 50% of gasoline vapor in oxygen-poor condition (O2 fraction was 12%).