In this study, CuX zeolite supported Mn and/or Ce oxides catalysts were synthesized by combining ion exchange and impregnation methods, and the zeolite X was generated using blast furnace slag (BFS). Doping Mn-Ce oxides onto the CuX catalyst, which has excellent resistance to SO2 +H2O, improved the catalyst's activity for NH3-SCR at lower temperature. In addition, electron transfer from Mn4+ to Ce3+ and Cu2+ was enhanced, and the concentration of isolated Cu2+ and chemisorbed oxygen species was higher in the Mn-Ce/CuX catalyst. Also, the Mn-Ce/CuX catalyst provided excellent SCR activity because of its high acid capacity, which allowed it to provide extra acid sites, and its high redox ability, which enhanced the re-oxidized and re-reduced cycles. Additionally, produced sulfates on the catalyst surface after SO2 and H2O poisoning might occupy Cu2+ active sites and affect the SCR process by competing with acid sites, nitrate species and intermediates on the Mn-Ce/CuX catalyst.