The aim of this work is to study oscillatory behavior of solutions for a fourth-order neutral nonlinear differential equation (b(x)(wm−1(x))γ)′+ ∑i=1jqi(x)f(w(gi(x)))=0, x≥x0. The results obtained are based on the Riccati transformation, integral averaging technique and the theory of comparison with second-order delay equations. The obtained results complements and generalize the earlier ones. Some examples are illustrated to show the applicability of the obtained results.