1. Introduction. This paper is concerned with fourth order differential equations of the form (L) (p(x)y) - q(x)y - r(x)y = 0, where p, q and r are assumed to be continuous, real-valued functions on the interval [a, °° ). In addition, it will be assumed throughout that p > 0, q ^ 0 and r^Oon [a, o° ), with r not identically zero on any subinterval. If q is a (non-negative) constant, then (L) is self-adjoint; otherwise (L) is non-self-adjoint. The objective of the paper is to study the oscillatory behavior of the solutions of (L). A non-trivial y is oscillatory if the set of zeros of y is not bounded above. If the set of zeros of y is bounded above, which implies y has only finitely many zeros, then y is non-oscillatory. Hereafter, the term solution will be interpreted to mean non-trivial solution. Various special cases of (L) have been studied in detail. In particular, we refer to the fundamental work of W. Leigh ton and Z. Nehari [5, Part I] on the self-adjoint equation (1) (P(x)y) - r(x)y = 0. M. Keener [3, Part I] continued the investigation of (1), concentrating on the oscillatory behavior of solutions. S. Hastings and A. Lazer [2] considered the self-adjoint equation (2) y(4) - r(x)y = 0, showing that (2) has a linearly independent pair of bounded oscillatory solutions when it is assumed that r E C ' [a, «> ), with r > 0 and r ' ^ 0 on [a, oo ). S. Ahmad [1] has also studied (2), giving necessary and sufficient conditions for the existence of a linearly independent pair of oscillatory solutions. Finally, we refer to the work of V. Pudei [6], [7] in which the equation (3) yW - q(x)y - r(x)y = 0 is considered.