This article is devoted to the study of the current state of development of cyber threats in the world and the identification of key areas of ensuring the security of organizations in accordance with the latest practices in the field of cybersecurity. The article highlights the importance of constantly updating and improving cybersecurity strategies in accordance with the latest trends and requirements of today’s digital environment. The main challenges faced by organizations in the field of cybersecurity are investigated, and effective approaches to their resolution are proposed. This approach allows not only to adapt to the constantly changing landscape of cyber threats but also increases the level of protection and reduces risks for organizational systems. The article emphasizes the importance of implementing and using cybersecurity frameworks as an effective tool for ensuring the stability and reliability of systems’ security. The use of such frameworks allows organizations to create a systematic approach to information security management, taking into account modern requirements and industry best practices. This approach helps to ensure the completeness of security measures, which is essential for successfully combating cyber threats in today’s digital environment. The article focuses on the importance of the protection of cardholder data and compliance with the PCI DSS standard. The storage and processing of such data requires a high level of security, as their unauthorized leakage or breach of integrity can lead to serious financial losses for organizations and loss of user trust. The PCI DSS standard establishes requirements for protecting payment information, including defining controls and procedures to prevent unauthorized access to cardholder data. The updated version of the standard, PCI DSS v.4.0, is an important step in the direction of improving security measures and countering modern cyber threats in this area. Its detailed analysis will allow organizations to maintain compliance with new requirements and ensure the security of cardholder card data at a high level.