Increasing renewables' portion in energy matrix around the world has made the scientists to propose innovative techniques for recovering the available waste heat of energy systems to produce excess energies in the Waste-to-X framework. This study proposes a green sustainable multi-generation energy system (MES), producing power, heat, cold, and potable water, driven by a hydrogen-fueled gas engine. The engine's heating potential is recovered to run some bottoming systems comprising proton exchange membrane electrolyzer (PEME), absorption/electrical chiller cycles (ACC/ECC), organic Rankine cycle (ORC), dryer unit, heat pump cycle (HPC), and reverse osmosis desalination unit. The combination of ACC with dryer and HPC is an innovative idea which utilized to produce heating load in this study. A detailed sustainability evaluation framework (technical and eco-environment) is derived to approve performance of the MES. The construction feasibility of the MES in different climatic conditions is sought by considering 5 case study cities around the world. Afterwards, best working fluid of the ECC/HPC and ORC is selected and then the sensitivity of the MES performance to design variables is investigated trough a comprehensive parametric study. Results illustrated that the MES shows the best performance in the city of Willington in which the emission of 84.8 tons of CO2 is prevented annually which is equivalent to saving of 16,291.6 m3 natural gas. The working fluid selection outputs proved that considering R22 and R123 for ECC/HPC and ORC leads the best techno-economic performance. The sensitivity study demonstrated that the highest and lowest influence of the MES's techno-economic performance is related to the ECC evaporator and ORC turbine temperatures, respectively. So that, increasing ECC evaporator temperature led to a relative variation of 8.2%, 4.5%, and 7.5% in energy recovery factor, exergy efficiency, and levelized cost of productions, respectively.