Oral Hygiene Instruction Research Articles

Effects of thyme on halitosis in gingivitis patients: Can thyme mouthwash prevent halitosis-A randomized trial.

Bad breath is a condition that negatively affects people's social interactions and quality of life. The aim of this study was to evaluate the effect of thyme mouthwash on intraoral halitosis, gingival index (GI) and plaque index (PI) in patients with gingivitis. In this retrospective study, 60 gingivitis patients (30 women/30 men) received initial periodontal treatment followed by oral hygiene instructions (OHI) and then were divided into four groups: The control group (C) received only OHI, while chlorhexidine (CHX) mouthwash was prescribed to the CHX group, Zinc acetate and CHX diacetate mouthwash was prescribed to the zinc acetate and CHX diacetate (ZnA) group, and the thyme (T) group was instructed to use thyme mouthwash. GI, PI and volatile sulfur compound (VSC) values were recorded at baseline and at the first week of treatment. The initial values of the recorded parameters did not differ significantly between the groups. In all groups, VSCs, GI and PI decreased after treatment (p=0.001). There was no significant difference between the PI values of the groups after treatment (p=0.188). On the contrary, the GI and VSC values after treatment were significantly different between the groups (p=0.001). GI values were highest in the control group and lowest in the CHX group. In terms of VSCs, a significant difference was found between groups T and C, and between groups T and ZnA (p=0.001). This study showed that the use of thyme mouthwash after periodontal treatment was effective in improving bad breath and gingivitis in gingivitis patients.

Effectiveness of an Oral Health Education Program Using a Smart Toothbrush with Quantitative Light-Induced Fluorescence Technology in Children

This randomized controlled trial aimed to educate patients and manage oral hygiene remotely via a smart toothbrush (ST) by using mobile applications and to improve oral hygiene and habits by evaluating the plaque state via images from a Q-ray cam, which is a quantitative light-induced fluorescence (QLF) digital imaging device. In total, 68 children (aged 6-12 years) were randomly divided into three groups. Group I was assigned an electro-toothbrush (ET), group II was assigned a smart toothbrush (ST), and group III used a manual toothbrush (MT). Each group used an assigned toothbrush and was checked after 1 and 3 months. Oral hygiene status was evaluated using the patient hygiene performance (PHP) index and fluorescent plaque index (FPI), which are presented in the QLF program. In addition, questionnaires on oral health behaviors and attitudes were also evaluated. There was a 0.24 decrease in the PHP index and a 1.40 decrease in the simple hygiene score three months later compared with the baseline in the ST group, with no significant difference between the three methods (p = 0.518, p = 0.626). Many group II participants said that ST helped with oral hygiene, and they were willing to use it continuously. In addition, all participants' brushing times and attitudes toward oral hygiene improved after oral hygiene education using a Q-ray cam. Therefore, the use of STs provided good dental health education and a plaque-decreasing effect to children aged 6-12 years old. Furthermore, the QLF device can be used as a useful tool for maintaining good oral hygiene in children.

Special aspects of treatment and adaptation of children with autism spectrum disorder at a dental appointment (literature review)

Relevance. Children with autism spectrum disorder (ASD) have poor self-care skills; they depend on sweet food, and their sensory integration is impaired. All of the above leads to poor oral hygiene. High rates of dental disease in these patients require searching for the most effective treatment and prevention methods. Special programs based on clinical manifestations and behaviour modification have been developed for children with ASD to adapt to dental appointments and oral hygiene education. In addition to traditional hygiene education, modern techniques, including electronic devices, are increasingly being introduced. Unfortunately, not all children can get used to dental manipulations, and the dentist has to resort to sedation or general anaesthes ia.Objective. To present up-to-date information about children's adaptation methods to dental appointments, prevention and treatment of oral diseases.Materials and methods. The literature analysis on the topic was the main study method. Publications were searched in the Medline PubMed and E-library databases by the keywords: 'treatment and prevention of diseases', 'children with ASD', 'adaptation' and 'hygiene education', according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.Results. The comprehensive approach to oral-disease treatment in children with ASD under general anaesthesia and sedation enables us to achieve excellent results with optimal comfort for both the patient and the pediatric dentist. The advantage of these methods is that the doctor can perform a larger volume of treatment and preventive measures during one visit.Conclusion. Children with autism need prevention and treatment of dental conditions. Available prevention programs need to be adapted to their disease and personality characteristics, using various methods of hygiene education.

Periodontal Treatment Needs of Patients with Chronic Kindey Disease

Objective: To assess the periodontal treatment needs of patients in different stages of chronic kidney disease Methodology: A Cross sectional comparative study was conducted in the department of Nephrology and Urology, Sharif Medical and Dental College, Lahore on 32 patients with chronic kidney disease in the time duration of one year. Data was collected after taking an informed consent from the patients. The demographic data along with a list of variables associated with chronic kidney disease was recorded using a structured questionnaire. Data collection was based on the following parameters: Community Periodontal Index of Treatment Needs (CPITN). Results: The highest percentage (10%) of patients who required no treatment (TN0) were stage 3 patients. Majority of the stage 5 (93.1%) patients required scaling, prophylaxis and oral hygiene instruction (TN2) followed by stage 4 (90.9%) and stage 3 (40%) respectively. None of the patients required complex treatment, scaling, prophylaxis and oral hygiene instructions (TN3) Conclusion: The highest percentage of patients with healthy periodontium were stage 3 patients. Periodontal pocket depths 4-5 mm were found to be in stage 4 patients the most followed by stage 5 and then stage 3. None of the patients had pocket depths of 6mm or more. Majority of the stage 5 patients required scaling, prophylaxis and oral hygiene instruction (TN2) followed by stage 4 and stage 3 respectively. None of the patients required complex treatment, scaling, prophylaxis and oral hygiene instructions (TN3). Keywords: Chronic kidney disease, periodontal treatment needs, oral hygiene instructions, oral prophylaxis, complex treatment

Periodontal Treatment Needs of Smokers in Comparison to Non-Smokers: A Comparative Study

Objective: To assess the periodontal treatment needs of smokers in comparison to non-smokers. Methodology: A Cross sectional comparative study was carried out on 100 patients, 50 smokers and 50 non-smokers, visiting Sharif Medical and Dental College, Lahore from June 2019 to July 2020. Intra-oral examination was done using the Community Periodontal Index of Treatment Needs (CPITN). Recorded data was coded, entered and analyzed using SPSS statistical Package version 23. Results: Majority of the smokers and non-smokers (100%) required oral hygiene instructions and had periodontal treatment needs (TN1). It was seen that a higher percentage of smokers (92%) required Scaling and prophylaxis and Oral hygiene instructions (TN 2) in comparison to non-smokers (36%). It was seen that 26 % smokers and none of the non-smokers required required complex treatment, scaling, prophylaxis and oral hygiene instructions (TN3). Conclusion: Majority of the smokers and non-smoke required oral hygiene instructions and had periodontal treatment needs (TN1). A higher percentage of smokers required Scaling and prophylaxis and Oral hygiene instructions (TN 2) as well as complex treatment, scaling, prophylaxis and oral hygiene instructions (TN3) in comparison to non-smokers Keywords: Periodontal treatment needs, smokers, non-smokers, Community periodontal index of treatment needs (CPITN).

Periodontal Treatment Needs of Women Across Different Trimesters of Pregnancy

Objective: To find the difference in the periodontal treatment needs of females across different trimesters of pregnancy. Methodology: A cross sectional comparative study was conducted among 44 pregnant visiting the gynecology department of Sharif Medical and Dental College and Raiwind Polyclinic, Lahore (community outreach program of the institute). Data was collected using the Community Periodontal Index of Treatment Needs (CPITN) Results: The highest percentage of females (24%) requiring no treatment (TN0) were in their third trimester. The majority of females in their second trimester (85.7%) required oral hygiene instructions and had periodontal treatment needs (TN1) and those in their first trimester (83.3%) required Scaling and prophylaxis and Oral hygiene instructions (TN 2). Conclusion: The highest percentage of females with healthy periodontium were in their third trimester. Periodontal pocket depth of 4-5 mm were seen the most on the clinical examination of women in their second trimester but least in third trimester. The highest percentage of females requiring no treatment (TN0) were in their third trimester. The majority of females in their second trimester required oral hygiene instructions and had periodontal treatment needs (TN1) and those in their first trimester required Scaling and prophylaxis and Oral hygiene instructions (TN 2). Keywords: Periodontal treatment needs, first trimester, second trimester, third trimester, Community periodontal index for treatment needs (CPITN)

A RARE CASE OF PAPILLON-LEFEVRE SYNDROME: A CASE REPORT

Papillon Lefevre syndrome is an extremely rare autosomal recessive disorder characterized by diffuse palmoplantar hyperkeratosis, rapidly progressive and devastating periodonitis, and pyodermas. The etiopathogenesis of the disorder is multifactorial, with genetic and immunological factors playing a major role. Consanguinity is a contributing factor. Genetic mutations of the gene 11q14- q21 encoding for cathepsin-c, a lysosomal protease that activates enzymes involved in a variety of inflammatory and immune processes. Management directed towards halting periodontal destruction using conventional periodontal treatment, systemic antibiotics, oral hygiene instructions, antiseptic mouth rinses. Palmoplantar hyperkeratosis usually treated with topical application of emollients, keratolytic agents, topical steriods and systemic retinoids.

Necrotizing gingivitis – diagnosis and treatment: a narrative review and case report

ChatGPT Introduction: Necrotizing periodontal diseases (NPD) are acute lesions with a rapid onset that may cause considerable periodontal tissue destruction. Among these conditions, necrotizing gingivitis (NG) is caused by microorganisms from the oral biofilm and is associated with predisposing factors such as psychological stress, HIV/AIDS, alcohol and tobacco consumption, malnutrition, inadequate oral hygiene, and other systemic conditions that may compromise the host immune response. Objective: The aim of this narrative literature review was to describe the available evidence on the diagnosis and treatment of NG and present a successfully treated case of NG in a 22-year-old woman. Case report: The patient was a smoker, had poor oral hygiene, and was experiencing psychological stress. Her complaints were abundant gingival bleeding and halitosis during the past two weeks preceding the first appointment. Clinical findings included considerable biofilm accumulation, generalized gingival bleeding, pseudomembrane, and necrotic tissue. Treatment consisted of supragingival scaling, professional prophylaxis, 0.12% chlorhexidine rinsing for two weeks, prescription of analgesics, and oral hygiene instructions. Results: The patient’s response to initial therapy was satisfactory. Successful clinical outcomes were observed at seven days after initial therapy, and the patient has remained stable without signs of disease recurrence for six months. Conclusion: Periodontal health and function were successfully reestablished.

Prevalence of Dental Caries among 10-17 Years Old Children of a Selected School of Narayanganj, Dhaka

Introduction: Dental Caries is the most common and frequent disease affecting 60- 90% of all children across the world. Because Dental caries later results into tooth pain, discomfort, eating disorder, edentulism, delayed language development. Approximately, 80% of children attend lower secondary school so ensuring to have preventive oral health services in school would help them stay healthy and ready to learn about oral diseases. Aim of the Study: The aim of this study was to assess the prevalence of dental caries among 10- 17 years old children of a selected school in Narayanganj. Methods: This was a descriptive type of cross-sectional study conducted at ‘Fotullah Pilot High School’, Narayanganj, Dhaka on 6th February 2016. Result: In total 252 children completed the study. In our study we found that among the total 252 subjects 58 were boys and 194 were girls. Total caries prevalence was found 53.97% where 27.20% were boys and 72.79% were girls. Significant Caries (SiC) Index was found 1.89. The Global Goals for Oral Health in the year 2000 proposed to reduce the SiC index among the 12-year-olds to less than 3 DMFT by the year 2015, globally. The mean DMFT value was found 0.7 for the age group (10-17) year’s old children. We also found mandibular caries rate 67.65% is higher than maxillary caries rate 32.35%. In case of boys the maxillary caries rate 45.94% is higher than girls 28.12%. And in case of girls the mandibular caries rate 72.73% is higher than boys 54.05%. Conclusion: Dental caries prevalence in rural areas of Bangladesh is lower than that of urban population. In this study we also found it satisfactory. But as development is progressing in rural areas, consumption of fast foods & chocolates is increasing day by day in rural areas as well which will increase caries prevalence in near future if oral hygiene instruction is not provided in school curriculums.

Effectiveness of non-operative approaches in active enamel carious lesions: a retrospective longitudinal study

The aim of the study was to investigate the effectiveness of non-invasive and micro-invasive treatments in active enamel carious lesions in high-caries-risk children. Clinical records of children treated in a dental school setting were retrospectively screened for active enamel carious lesions treated non-invasively (topical fluoride applications, oral hygiene instruction, or dietary guidance) or micro-invasively (sealant). The control of active carious lesions was set as the main outcome established by the combination of inactivation and non-progression of the lesions based on Nyvad and ICDAS criteria, respectively. Individual and clinical factors associated with the outcome were analyzed by Poisson regression. The sample consisted of 105 high-caries-risk children with a mean age of 8.3 (± 2.4) years. From a total of 365 active enamel carious lesions, most lesions (84.1%) were active non-cavitated carious lesions (ICDAS scores 1 and 2) and only 15.9% presented localized enamel breakdown (ICDAS score 3). Of these, 72.6% were inactivated and 92.1% did not progress (mean time of 6.5 ± 4.1 months). The prevalence of controlled carious lesions was higher among children older than 6 years (PR:1.43; 95%CI:1.00-2.03; p = 0.04) and in those with better biofilm control (PR:0.99; 95%CI: 0.98-0.99; p = 0.03). Non-operative approaches are effective for controlling active enamel carious lesions. The majority of active enamel carious lesions became inactive and did not progress after treatment. Caries control was associated with older children and better biofilm control.

Predictive Risk Factor Analysis of Oral Submucous Fibrosis among Gond Tribes of Central India: A Cross-Sectional Study

ABSTRACT Introduction: Oral submucous fibrosis (OSMF) is a potentially malignant disorder characterized by fibrotic changes in the oral mucosa. It is a significant public health concern, particularly among certain ethnic populations. The Gond tribes of Central India represent one such population, and the prevalence and risk factors associated with OSMF among them remain largely unexplored. This study aims to conduct a predictive risk factor analysis to identify the factors associated with OSMF among the Gond tribes and provide insights into the etiology and pathogenesis of the disease within this specific population. Materials and Methods: A cross-sectional study was conducted among the Gond tribal population of Central India. A total of 800 participants were included in the study. Oral examinations were conducted by trained researchers to assess the presence of OSMF and other oral health conditions. Demographic and socioeconomic data were collected, including age, gender, education level, occupation, and household income. Lifestyle factors such as tobacco and betel nut chewing, alcohol consumption, and oral hygiene practices were assessed through structured questionnaires. Dietary patterns and nutritional status were evaluated, and oral health-related factors such as dental caries, periodontal health, and other oral lesions were examined. Multivariate analysis was performed to identify independent risk factors associated with OSMF among the Gond tribes. Results: The prevalence of OSMF among the Gond tribes was 12.5%. Demographic analysis revealed a balanced representation of genders, with a range of age groups included. Lifestyle factors such as tobacco and betel nut chewing were prevalent among the Gond tribes, with a significant proportion of participants reporting regular use of these substances. Poor oral hygiene practices and undernutrition were also identified as risk factors. Dietary patterns showed a high consumption of carbohydrate-rich foods and a relatively low intake of fruits and vegetables in addition to OSMF. Conclusion: This study provides valuable insights into the prevalence and risk factors associated with OSMF among the Gond tribes of Central India. The findings highlight the need for targeted interventions addressing tobacco and betel nut chewing, poor oral hygiene practices, advanced age, low education level, and undernutrition within this population. Comprehensive oral health promotion programs, including tobacco cessation initiatives, oral hygiene education, nutritional interventions, and improved access to dental care, are crucial for reducing the prevalence of OSMF and improving oral health outcomes among the Gond tribes. Future research should focus on longitudinal studies to further elucidate the causal relationships and long-term impact of these risk factors on the development and progression of OSMF within the Gond tribal population.

Cysts of Oral Cavity: Odontogenic Keratocyst; A Rare Case Report with a 6-Year Follow-Up

Aim: Odontogenic keratocyst is one of the rare odontogenic cyst, commonly affecting the mandible. It has a special mention in the field of oral surgery due to its varied presentation and high recurrence rate. There have been a few cases reported of outcomes of treatment of odontogenic keratocysts. The aim of this report was to illustrate the case of OKC in a patient and to describe the follow-up information and successful treatment of its. Methods: A 18-year-old Turkish girl was referred by her dentist to the periodontology clinic of the Faculty of Dentistry in November 2017, for the treatment of cyst in the mandibulary incisor region. The diagnosis of odontogenic keratocyst suggested clinically and radiographically was confirmed by the histopathological study. Treatment consisted of oral hygiene instruction, periodontal-endodontic treatment and resection of cyst. Results: Four weeks after surgery healing was occurred and six years later area of the lesion appeared completely normal as clinical and radiographically. There were no signs of local recurrence after a 6-year follow-up. Conclusion: The odontogenic keratocyst was treated successfully by surgical periodontal treatment.

Oral hygiene awareness and practice in orthodontic patients in Makkah city: A cross sectional study.

To evaluate the level of oral hygiene awareness and practice among orthodontic patients that have fixed appliances and investigate the differences in awareness as per age, gender, and education qualification. A cross-sectional study with 250 patients was included. A questionnaire was used to collect information regarding the patient's oral hygiene. The level of awareness and oral hygiene practice was significantly higher among females, with a consistent stepwise increase toward older ages. Also, increased with higher education level, longer duration since getting the appliance, and receiving instructions from the orthodontist. Oral hygiene instructions received by the orthodontist play an important role in the patient's awareness level. Also, many predictors have a significant effect on the patient's cooperation in practicing oral hygiene measures.

The impact of technology on patient knowledge acquisition and retention of oral hygiene instructions and associated risks

ObjectiveThe aim of the study was to assess dental patients’ knowledge and perceptions of the risks associated with orthodontic treatment and oral hygiene instructions given at the start of their treatment regimen. MethodsThe sample group included dental patients aged 12–16 years. Half of the participants were taught using Augmented Reality (AR) technology, while the other half were taught using traditional methods, such as paper-based leaflets. We then assessed retention of the Oral Hygiene Instructions (OHI) and their awareness of the risks associated with orthodontic treatment. This objective was achieved through a knowledge-based survey. ResultsThe feedback from the participants was highly positive and favorable toward AR. ConclusionThe videos and leaflet materials were provided to the patients, these two materials effects on patients to understand the information given, but, the group watching the videos had greater scores than those participants reading the leaflet.

Subsiding of Periodontitis in the Permanent Dentition in Individuals with Papillon-Lefèvre Syndrome through Specific Periodontal Treatment: A Systematic Review.

Papillon-Lefèvre syndrome (PLS) is a rare hereditary disease characterized by palmoplantar hyperkeratosis (PPK) and periodontitis in the primary and permanent dentition, usually resulting in edentulism in youth. Subsiding of PLS-associated periodontitis through specific therapy has occasionally been reported. We aimed to systematically assess periodontal treatment strategies that may decelerate disease progression. A systematic literature search was conducted at PubMed/LIVIVO/Ovid (Prospero registration number CRD42021223253). Clinical studies describing periodontal treatment success-defined as loss of ≤four permanent teeth because of periodontitis and the arrest of periodontitis or probing depths ≤ 5 mm-in individuals with PLS followed up for ≥24 months. Out of the 444 primarily identified studies, 12 studies reporting nine individuals were included. The timely extraction of affected or, alternatively, all primary teeth, compliance with oral hygiene instructions, supra- and subgingival debridement within frequent supportive periodontal care intervals, and-in eight patients-adjunctive systemic antibiotic therapy (mostly amoxicillin/metronidazole) effected a halt in disease progression. The suppression of Aggregatibacter actinomycetemcomitans below the detection limit was correlated with the subsiding of periodontitis. Successful controlling of PLS-associated periodontitis may be achieved if high effort and patient compliance are provided.

Localized Necrotizing Periodontitis: A Possible Oral Manifestation of COVID-19

We investigated an unusual report of localized necrotizing periodontitis coinfection in patients with mild COVID-19. Male patient, 30 years old, with previous medical history of hypovitaminosis, immunized with two doses of the Pfizer® vacci ne, attended in a dental college in northern Brazil with an acute dental emergency reporting itching, halitosis, intense gingival p ain and spontaneous bleeding, mild fever of 37.8ºC, dry cough, muscle pain and nausea. Metronidazole and chlorhexidine were prescribed to improve the necrotizing condition, to treat periodontitis scaling and root planing (SRP) were performed associated with chlo rhexidine irrigation and oral hygiene instructions, which treated the patients conditions. COVID-19 coinfections are possible, specially, oral bacterial infections which is demonstrated in this report, so correct treatment is necessary for both infections. This letter d escribes the first known occurrence of severe localized necrotizing periodontitis in the urban area of Brazil's Amazon region.

Effectiveness of brief motivational interviewing on perceived importance, interest and self-efficacy of oral health behaviors: A randomized clinical trial.

To investigate periodontal patients' perceived importance, interest and self-efficacy of oral hygiene (OH) behaviors. Secondary outcomes from a randomized single-site examiner-blinded clinical trial investigated the control group (traditional oral hygiene instructions) and the test group (brief motivational interviewing) over four time points. Analyses were performed using R version 4.1.1. Sixty participants were eligible, and 58 completed the pre and post questionnaires for a 97% response rate. Importance was higher in the test group for good oral health and daily oral self-care (4.86 vs. 4.80). Interest in taking care of teeth and gums and changing a homecare routine was higher in the test group (4.89). Self-efficacy was higher in the test group for taking care of teeth and gums (4.18 vs. 4.07), making a change to improve oral health (4.29 vs. 4.27), and maintaining a change long-term (4.32 vs. 4.17). Statistical significance for self-efficacy was achieved for maintaining an OH behavior long-term. A brief motivational interviewing intervention was superior to enhance perceived importance, interest and self-efficacy of oral hygiene behaviors. Contrary to previous motivational interviewing research, this study used a novel approach to evaluate MI-fidelity to determine the most effective MI strategies to support self-efficacy.

The Relationship between Mother's Knowledge About the Occurrence of Oral Trush and the Immune System of Old Babies 0-6 Months

Oral thrush is a common condition in the oral cavity that can affect individuals of all ages, including infants and toddlers. This research focuses on studying the relationship between maternal knowledge about oral thrush and the immune system of infants aged 0-6 months. Conducted in 2023 in Pidoli Lombang Village, Panyabungan District, Mandailing Natal Regency, this study employs a descriptive approach within a case study framework. A total of 41 participants were selected using a total sampling technique. Data was collected through a questionnaire consisting of 20 statements and analyzed through editing, coding, and tabulating methods. The findings reveal a significant correlation between maternal knowledge about oral thrush and the immune system of infants. The study underscores the importance of health workers in providing comprehensive health services, particularly in oral hygiene education, to enhance public awareness and prevent oral thrush in infants.

The dental phenotype of primary dentition in SATB2-associated syndrome: a report of three cases and literature review

BackgroundSATB2-associated syndrome (SAS; OMIM: 612,313) is an autosomal dominant inherited multisystemic disorder caused by several variants of the SATB2 gene. SAS is characterized by intellectual disability, developmental delay, severe speech anomalies, craniofacial anomalies, and dental abnormalities. Here, we report the dental phenotype of primary dentition of three Chinese children with SAS.Case presentationAll three cases with SAS showed intellectual disability, speech and language anomalies, and palate anomalies. For the dental phenotype, all three cases showed macrodontia, crowded dentition, extensive caries, periapical abscesses and fistulas. Radiographs showed the wide-open root apex of deciduous teeth, loss of mandibular second bicuspids, delayed root formation of permanent teeth, rotated teeth, and taurodontism. Sanger sequencing of case 1 showed that there was a heterozygous code shift variation, c1985delT (p.F662Sfs*9) in the SATB2 gene, which has not been reported in literature. Root canal therapy, carious restoration, and teeth extraction were managed promptly, while preventive dental care was given regularly.ConclusionsThe dental phenotype of primary dentition in SAS may show macrodontia, crowded dentition, severe caries, wide-open root apex of deciduous teeth, loss of mandibular second bicuspids, delayed root formation of permanent teeth, rotated teeth, and taurodontism. Regular oral hygiene instructions and preventive dental care are both required.

Systematic review on dental caries preventive and managing strategies among type 2 diabetic patients.

The purpose of this systematic review was to evaluate current evidence to prevent and manage dental caries in patients with type 2 diabetes mellitus (T2DM). Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the Participants, Intervention, Comparison, Outcomes and Study Design (PICOS) strategy was used to formulate a structured search: systematic search of PubMed, Cochrane Library, MEDLINE via Ovid, EMBASE, Scopus, Web of Science, and Lilacs without any date limit and/or language restrictions. Two independent reviewers performed data extraction and risk of bias assessments in the included studies. Data homogeneity was assessed according to interventions for treating dental caries in T2DM. Statistical analyses were performed with JMP®. Two studies out of 909 were included in the systematic review. Only quantitative studies involving topical applications for management of dental caries in patients with T2DM were included. One study assessed the effect of intensive oral hygiene care program including toothbrushing and interdental cleaning using interproximal brushes and/or dental floss and supragingival debridement by dental hygienist with educational brochures in T2DM, while another investigated the immunologically active salivary substitutes with using Oral Hygiene Instructions (OHI), mouthwash, and moisturizing gel for 6 months. Intensive oral hygiene care program or immunologically active salivary substitutes with using OHI, mouthwash, and moisturizing gel for 6 months were reported to reverse/arrest dental caries in patients with T2DM. The current randomized controlled clinical trials demonstrated that regular extensive oral health education using interdental cleaning aids, mouthwash, moistening gel, and saliva substitutes including lactoperoxidase, lysozyme, glucose oxidase, and lactoferrin could control oral inflammation and contribute to the management of dental caries in patients with T2DM. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020197507, identifier: CRD42020197507.