Oral Conditions Research Articles

A Tissue-Engineered Model of T-Cell–Mediated Oral Mucosal Inflammatory Disease

T-cell-mediated oral mucocutaneous inflammatory conditions including oral lichen planus (OLP) are common but development of new treatments aimed at relieving symptoms and controlling OLP progression are hampered by the lack of experimental models. Here, we developed a tissue-engineered oral mucosal equivalent (OME) containing polarised T-cells to replicate OLP pathogenesis. Peripheral blood CD4+ and CD8+ T-cells were isolated, activated and polarised into Th1 and cytotoxic T-cells (Tc). OME were constructed by culturing oral keratinocytes on an oral fibroblast-populated hydrogel to produce a stratified squamous epithelium. OME stimulated with IFN-γ and TNF-α or medium from Th1 cells caused increased secretion of inflammatory cytokines/chemokines. A model of T-cell-mediated inflammatory disease was developed by combining OME on top of a Th1/Tc-containing hydrogel, followed by epithelial stimulation with IFN-γ/TNF-α. T-cell recruitment towards the epithelium was associated with increased secretion of T-cell chemoattractants CCL5, CXCL9 and CXCL10. Histological assessment showed tissue damage associated with cleaved-caspase-3 and altered laminin-5 expression. Treatment with inhibitors directed against JAK, KCa3.1 channels or clobetasol in solution and/or via a mucoadhesive patch prevented cytokine/chemokine release and tissue damage. This disease model has potential to probe for mechanisms of pathogenesis or as a test platform for novel therapeutics or treatment modalities.

Implication of Exclusive Breastfeeding in Early Childhood Dental Disorders: Large Cohort Evidence, US National Survey of Children Health.

Purpose/Objective: Frequent consumption of fermented carbohydrates and bottle feeding contribute to the development of early childhood caries (ECC). There are no substantial findings on the effects of breastfeeding patterns on oral health conditions in children in the United States. We aimed to assess the nexus between exclusive breastfeeding during the first 6 months and oral health disorders, namely toothache, decayed teeth, or unfilled cavities in early childhood. Materials and Methods: Design: Cross-sectional epidemiologic design of nationally representative data collected via telephone surveys in the United States was utilized. Setting: National Survey of Children's Health, 2012 Participants: Population-based random sample of parents/guardians of 24,655 children aged 6 months to 5 years. Main Outcome and Measure: The primary outcome was the presence of oral health disorders (OHD) in children, defined as the parent-reported occurrence of one or more of the following conditions in the past 12 months: toothache, decayed teeth, or an unfilled cavity. This was assessed through a single composite question in the survey, asking parents/guardians if their child had experienced any of these specific oral health issues within the previous year with a binary (yes/no) response option. Results: Among 24,655 children aged 6 months to 5 years, 2392 (9.7%) had experienced an oral health disorder (OHD) in the previous 12 months. In unadjusted analysis, children exclusively breastfed for 6 months were 28% less likely to present with OHD compared to never-breastfed children (OR = 0.72, 95% CI, 0.52-0.98). However, after adjusting for key factors, including maternal health and race/ethnicity, this association was no longer statistically significant (aOR = 1.11, 95% CI 0.79-1.57). Significant predictors of OHD included maternal health (aOR for fair/poor vs. excellent/very good maternal health = 1.79, 95% CI 1.08-2.69) and race/ethnicity, with a higher prevalence among non-Hispanic Black (12.9%) and multi-racial children (12.6%) compared to non-Hispanic White children (7.7%). Conclusions and Relevance: While exclusive breastfeeding for the first six months of life was not found to be a significant predictor of pediatric oral health outcomes after adjustment, maternal health and race/ethnicity were significant determinants of oral health disorders. These findings underscore the importance of comprehensive healthcare approaches that consider maternal well-being and socio-demographic factors. Future research should explore interventions targeting these factors to improve pediatric oral health outcomes.

Recent Developments in the Non-Pharmacological Management of Children's Behavior Based on Distraction Techniques: A Concise Review.

Oral diseases and conditions affect children's oral health and negatively influence their overall health. Early detection and intervention are important in mitigating these negative consequences. However, dental fear and anxiety (DFA) regarding dental procedures often hinder children from seeking necessary dental care. Non-pharmacological behavior management strategies, such as distraction techniques, are commonly adopted to manage children's behaviors. Distraction techniques have been developed rapidly in recent years and are widely accepted by both health professionals and parents due to their noninvasive and low-cost nature. This concise review aims to summarize current distraction techniques applied during dental treatments, especially for children. The most commonly reported techniques for children are audio distraction, audio-visual distraction, tactile distraction, olfactory distraction, and gustatory distraction. Audio distraction techniques involving music and storytelling help children relax. Audio-visual distraction techniques help to divert children's attention from the dental treatment. Tactile stimuli can reduce the transmission of pain signals. Olfactory stimuli can help children feel comfortable and relaxed. Gustatory distraction involving sweet substances can create a positive environment. These distraction techniques effectively reduce DFA in children and improve their satisfaction with dental procedures. As technology continues to develop, further research is needed to provide more robust, evidence-based guidance for dentists using distraction techniques.

Evaluating the clinical significance of color stability in nanohybrid composite resins: a comparative study of local and international brands

Aims: The objective of this study was to evaluate the color stability of five nanohybrid composite resins, including locally produced Turkish brands and an international brand, after exposure to staining and brushing simulations over time. Methods: Five nanohybrid composite resins; Filtek Z550 (FLT), Dolgunn (DLG), RubyComp Nano (CMP), Nova Compo C (NVC), and Parion (PRN) were tested. Specimens underwent staining and brushing simulations designed to replicate clinical oral conditions. The staining process involved immersing the specimens in a coffee solution for 8 hours per day over a 10-day period to simulate short-term staining (t1), and for 12 days to simulate long-term staining equivalent to 1 year (t2). Brushing cycles were used to replicate the mechanical wear caused by daily oral hygiene practices. Color measurements were recorded at baseline (t0), after 10 days of staining (t1), and after 1 year of simulated staining and brushing (t2). Additional analyses were conducted using Energy-dispersive X-ray spectroscopy (EDX) and Scanning Electron Microscopy (SEM) to investigate structural and surface characteristics. Statistical analysis was performed using generalized linear models and two-way robust ANOVA to assess the significance of differences in color stability, with a significance level set at p

Oral diseases and systemic conditions: correlation analyses from the Colombian national health records between 2016 and 2023.

Prevalence of oral, metabolic, circulatory, and nutritional diseases has tended to increase globally. As these diseases have common contributing factors, such as unhealthy diets, evaluating their epidemiological trends and the relation between them is relevant. In Colombia, the Ministry of Health records the frequency of consultation for these diseases through the Integrated Social Protection Information System. It facilitates the evaluation of their epidemiological behavior at the population level. To analyze and correlate the burden of oral diseases (caries and periodontitis) with respect to nutritional, circulatory and metabolic pathologies, as well as their relationships with socioeconomic indices in Colombian regions from 2016 to 2023. This study analyzes retrospective data collected between 2016 and 2023 by the National Health Registry in Colombia (SISPRO) according to the ICD-10. Sociodemographic data and the number of disease consultations were extracted. The number of consultations for oral diseases was correlated with systemic pathologies, socioeconomic indices through the Spearman test. Associations were explored via multiple linear regressions. A Principal Component Analyses (PCA) was conducted to identify patterns between socioeconomic, oral and systemic disease variables, as well as to reduce the complexity of the analysis by creating clusters that capture the greatest possible variability in the data. The average number of consultations per biennium was 24.550.435 being the highest number for 2018-2019. The highest percentage of consultations was related to extensive caries, followed by chronic gingivitis. Moreover, consultations for oral diseases were found to correlate with systemic pathologies. All socioeconomic indices were associated with caries and/or periodontal diseases. This study is the first in Colombia that uses national data on diagnoses assigned to medical and dental consultations. PCA revealed a clustering pattern of pathologies suggesting that they are highly associated one to each other. Correlations between consultations for oral and systemic diseases stratified by life cycle and socioeconomic indices highlight the importance of conducting epidemiological and public health characterizations and their associations. Identifying these factors is imperative in the prevention and management of both diseases.

Decisional needs for older adults, home health care nurses and dental hygienists during team-based oral health assessments in ordinary home settings – a qualitative study

BackgroundParticipation by all actors involved in health planning is a prerequisite for person-centred care and healthy ageing. Understanding the multiple knowledge needs and the values that shape oral health assessments in home settings is important both to enable participation in oral health planning and to contribute to healthy ageing.ObjectiveThe aim of this study was to investigate decisional needs during oral health assessments in ordinary home settings from the perspectives of older adults, home health care nurses and dental hygienists.MethodsData was collected in ordinary home settings through 24 team-based oral assessments and 39 brief, semi-structured interviews including older adults (n = 24), home health care nurses (n = 8) and dental hygienists (n = 7). Data was analysed using content analysis with a deductive approach. The analysis was guided by the Ottawa Decision Support Guide.ResultsThe analysis revealed that all participants considered participation in decision-making important but until now, older adults might not have participated in making decisions regarding oral health issues. The older adults considered participation important because the decisions had a strong impact on their lives, affecting their health. The professionals considered decision-making important for knowing what step to take next and to be able to follow up and evaluate previous goals and treatments. Organizational and personal barriers for shared decision-making among home health care nurses and dental hygienists were identified. Of the 24 older adults, 20 had different oral health conditions that objectively indicated the need for treatment. An initial important decision concerned whether the older adult wanted to make an appointment for dental care, and if so, how. Another decisional conflict concerned whether and how assisted oral care should be carried out.ConclusionIt is important for key participants in ordinary home settings to participate in interprofessional teams in home health care. To further anchor this in theory, conceptual models for professionals from different care organizations (municipal care, dental care) need to be developed that also involve older adults as participants. Future research could bridge theory and practice by including theories of learning while exploring interorganizational oral health planning in home settings.

Force Decay Behavior of Orthodontic Elastomeric Chains in Simulated Oral Conditions.

Background Elastomeric chains are widely used for incisor retraction and space closure. However, the force they exert diminishes over time, and this makes it difficult to determine the actual force transmitted to the dentition. The force decay may also be affected by exposure to saliva, foods, beverages, and prophylactic agents. Objective To assess the force degradation of four commercially available orthodontic elastomeric chains (AlastiK, 3M; Generation II Power Chain, Ormco; Elastic Chain, Morelli; and Plastic Chain, American Orthodontics) over 28 days in simulated oral conditions using tooth movement and a prophylactic fluoride rinse regimen. Method A total of 80 chain samples, with 20 samples of each chain type having four loops each, were stretched to 25 mm on custom-fabricated acrylic resin jigs with provision for a space closure mechanism. The samples were divided equally into two groups: a control group, in which ten samples of each chain type were maintained in artificial saliva at 37°C, and a test group, in which ten samples of each chain type were maintained in artificial saliva at 37°C and additionally subjected to simulated tooth movement with jig closure of 0.25 mm/week and a twice-daily regimen of prophylactic fluoride rinse. Force decay was measured using a digital force gauge at the time of engagement on the jigs, at one hour, four hours, and at one, seven, 14, 21, and 28 days. Percentage force decay was calculated, and the results were subjected to one-way analysis of variance (ANOVA), post-hoc Tukey, post-hoc Bonferroni, and 't' test. Results Maximum force degradation was observed at one day for all four chain materials in both groups, followed by a steady force loss over 28 days, the difference being significant for all materials at various time intervals (p<0.05). No significant difference was observed between any material at any given time in the control group (p>0.05); however, significant differences were observed in the test group. Under simulated oral conditions, force decay was maximum for the Plastic Chain, American Orthodontics (67.9 ± 6.24%), and minimum for the Generation II Power Chain, Ormco (51.9 ± 9.78%) at the end of the test period. Conclusion Plastic Chain, American Orthodontics, and AlastiK, 3M chain, exhibited higher force decay when compared to Generation II Power Chain, Ormco, and Elastic Chain, Morelli. Simulated oral conditions significantly affected the force decay of elastomeric chains, and it may be desirable to change elastomeric chains at 14 days for optimum retraction force.

Prevalence of dentine hypersensitivity, erosive tooth wear, gingival recession and periodontal health in seven European countries

ObjectivesTo determine the prevalence and associated risk indicators for dentine hypersensitivity (DH), erosive tooth wear (ETW), gingival recession (GR), and gingival inflammation (bleeding on probing, BOP), with clinical and questionnaire data from seven European countries. MethodsA cross-sectional, observational, seven-European country, epidemiological study in systemically healthy adults. Participants completed a questionnaire regarding oral hygiene, diet and lifestyle factors. A clinical examination, by calibrated examiners, measured DH (Schiff; participant yes/no), ETW (basic erosive tooth wear examination, BEWE), GR (mm), and BOP (yes/no). Results3551 participants completed the study, mean age 44 ± 17.4, 43.6 % male, 26.1 % rural dwellers. DH (Schiff ≥ 1) was seen in 75.9 % of participants, ETW (BEWE ≥ 1) in 97.6 %, GR (≥1 mm) in 87.9 %. 65.7 % participants had BOP ≥ 10 % sites, 34.3 % BOP<10 % with probing depths ≤3 mm. DH, ETW, GR and BOP increased markedly during young adult life. Thereafter, GR and ETW continued to increase, DH declined after around age 38–47, and BOP plateaued after age 48. DH was significantly associated with ETW (p < 0.001) and GR (p < 0.01); GR was significantly associated with BOP on lingual surfaces (p = 0.017). There were significant associations between increased full mouth BOP ≥ 10 % and reduced brushing duration and exercise frequency (p < 0.001); increased DH and heartburn (p < 0.001); decreased DH (p < 0.001), ETW (p < 0.001) and BOP ≥ 10 % (p = 0.002) with powered toothbrush use. ConclusionsPrevalence of oral conditions assessed was high, greater than in the majority of the GR, DH and ETW literature. Periodontal health was seen in a third of sampled individuals. All these conditions varied markedly by country and age. Clinical significanceOral diseases and conditions were highly prevalent throughout the seven European countries investigated. For the majority, these conditions are eminently preventable and treatable by changing behaviours. Upstream policy changes are needed to address these health challenges, to raise awareness and to empower individuals with oral health education and support.

Modifiable Risk Factors Related to Oral Diseases in Youth Cuban Baseball Sportsmen

Background Oral health care closes the cycle of medical assistance integrated with sports, becoming a specialized service of great value in Cuba; however, oral diseases in young athletes are very frequent. For effective prevention, it is necessary to know the modifiable risk factors related to these diseases. Objective This study aimed to determine the relationship between risk factors and oral diseases in baseball sportsmen from the sports initiation school of Villa Clara, Cuba. Material and Methods A descriptive, correlational, and cross-sectional study was carried out in the young baseball athletes (N=60) of the 15U (n=30) and 18U (n=30) divisions (M=15.33; SD=1.49). Data were analyzed using empirical frequency distribution and descriptive statistics. Data normality was tested using asymmetry, kurtosis, and the Kolmogorov-Smirnov test. Mann-Whitney U test was used to determine differences in the risk factors and oral diseases between divisions, and the Tau_b Kendall correlation coefficient was used to determine relationships between both groups of variables. Results Improper tooth brushing, cariogenic diet, and inefficient oral hygiene were the main risk factors, while dental caries, gingivitis, and malocclusions were the oral diseases most notable. Athletes of higher division have greater toxic habits and a cariogenic diet; however, they brush more frequently and have more efficient oral hygiene. Except for the presence of malocclusions, the rest of the conditions are related to the determined risk factors. Conclusion The knowledge about the relationship between risk factors and oral conditions allows to base the design of educational intervention actions focused on the promotion of adequate oral health behaviors in the athletes, which shows the relevance of odontology in sports.

Effect of inulin on structural, physicochemical, and in vitro gastrointestinal tract release properties of core-shell hydrogel beads as a delivery system for vitamin B12

In this study, core-shell hydrogel beads were developed as a controlled-release delivery system for vitamin B12. Vitamin B12-loaded microgels (MG) were prepared using gellan gum (GG). Core-shell hydrogel beads were produced by incorporating MG into pea protein isolate (PPI) and sodium alginate (AL) matrix filled/coated with different concentrations (0 %, 1 %, 3 %, 5 %, and 10 %) of inulin (IN). Based on XRD analysis, MG was successfully incorporated into core-shell hydrogel beads. In FE-SEM and FT-IR analyses, the smoother surface and denser structure of the beads were observed as IN concentration increased due to hydrogen bonds between IN and the beads. The encapsulation efficiency increased from 68.64 % to 82.36 % as IN concentration increased from 0 % to 10 %, respectively. After exposure to simulated oral and gastric conditions, core-shell hydrogel beads exhibited a lower cumulative release than MG, and a more sustained release was observed as IN concentration increased in simulated intestinal conditions.

Recent Advances in the Therapeutic Potential of Fucoidan: A Comprehensive Review

Fucoidan, a polysaccharide primarily comprised of l-fucose and sulfate groups possesses a unique chemical structure that underpins its notable therapeutic potential. Its remarkable biological functions such as antioxidant, anticarcinogenic, antiviral, anticoagulant, antithrombotic, immunoregulatory, and anti-inflammatory properties have gained substantial recognition in the global food and pharmaceutical industries. This review highlights recent advancements in understanding fucoidan’s potential biological activities that could innovate treatments for oral infections and inflammatory diseases. A systematic search for relevant articles published between January 2000 and July 2024 was conducted across multiple databases, including PubMed, Scopus, Web of Science, and Google Scholar. Manual searches of references listed in the identified publications were conducted to ensure thorough coverage of the subject. The inclusion criteria focused on peer-reviewed articles in English-language, encompassing meta-analysis, randomized clinical trials, cohort studies, case-control studies and in vitro studies. Exclusion criteria comprised abstracts, opinion pieces, review articles not providing original analysis, and studies not directly addressing the therapeutic effects of fucoidan. This rigorous selection process aims to encapsulate the most significant and recent scientific evidence regarding the therapeutic applications of fucoidan. Fucoidans, with their diverse pharmacological properties, hold promising therapeutic potential which could emerge as a novel therapeutic option for treating wide range of diseases. Fucoidans have demonstrated anti-inflammatory properties, which may be beneficial in reducing inflammation related to periodontal diseases and other oral conditions. We anticipate that this review will serve as a foundational guide and inspire continued product development centered on fucoidan. Clinical relevance to interdisciplinary dentistry:  Fucoidan, a polysaccharide rich in fucose holds wide pharmacological effects  Enhancement of oral health outcomes through anti- inflammatory properties  Antimicrobial activity against oral pathogens  Wound healing property may aid in periodontal diseases.

Prevalence of dental carries among school-going children aged 7–13 years in Kabul City

BackgroundDental caries is a major, multifactorial oral condition that causes the demineralization of tooth enamel and impacts approximately half of the world’s child population. This study aimed to determine the prevalence of dental caries among school-going children aged 7 to 13 years in Kabul city.MethodsThis descriptive cross-sectional study was conducted with 491 students aged 7 to 13 years in Kabul during the first half of 2019. A multistage cluster sampling method was used, in which educational zones, schools, and classes were selected. The data were collected using pre-structured questionnaires through face-to-face interviews and oral examinations of students using dental probes and mouth mirrors while adhering to infection control protocols. The collected data were analyzed using Statistical Package for Social Science version 21.0, and a p-value < 0.005 was considered as statistically significant.ResultsThe average age of the study participants was 9.9 ± 1.8 years. Boys made up approximately 45% of the participants, while 54.8% were girls. The overall prevalence of dental caries was 78.8%, with 62.1% in deciduous teeth and 42.8% in permanent teeth. Among students who did not brush their teeth, the prevalence of dental caries was 84.8%, compared to 81.7% for those who brushed once daily, 78.7% for those brushing twice daily, and 67.4% for those brushing three times daily (p = 0.022). About 10% of students had dental calculus, with a prevalence of 17.0% among those aged eleven and older, 10.0% among students aged nine to ten years, and 5.9% among students aged eight and younger (p = 0.006). Poor oral hygiene affected nearly one-third of the students, with 34.2% among boys and 30.9% among girls. Poor oral hygiene was more prevalent in students aged eight and younger (38.8%) compared to those aged eleven and older (25.9%) (p = 0.023).ConclusionsThe prevalence of dental caries among students aged 7 to 13 years in Kabul schools was similar to that in most developing countries. The prevalence of dental calculus was greater among students aged eleven years and older. Over 99% of the students surveyed had not undergone any dental treatment.

Associations between disability type and untreated dental decay among community dwelling US adults.

Individuals with disabilities face elevated risks of adverse oral health outcomes compared with the general population, including worse periodontal health, increased edentulism, and untreated dental decay. Given the varied impacts of different disabilities on people's health and well-being, this study aims to investigate diverse associations between untreated decay and cognitive, physical, emotional, and sensory disabilities among US adults. This cross-sectional study analyzed questionnaire and clinical examination data on 7084 adults (≥20 years) from the 2015-18 National Health and Nutrition Examination Survey cycles. Sociodemographics, oral health behaviors, health conditions, and disability were all examined. The prevalence of tooth decay was calculated as the proportion of adults with untreated decay. Survey-weighted multivariable logistic regression was used to assess associations between disability and untreated decay. In general, untreated decay was more than twice as prevalent in individuals with three or more disabilities as in those without any disabilities (34.5% vs. 13.2%, p < 0.001). After adjusting for confounders, lack of functional dentition was the most significant predictor of untreated decay prevalence (adjusted odds ratio: 2.97, 95% CI: 2.37-3.72). Other significant factors were younger age (20-44), non-Hispanic black race or ethnicity, low-income status, having an underlying chronic condition, not having a past-year dental visit, symptomatic dental visits, and current tobacco use. No associations were found between disability type (cognitive, emotional, physical, and sensory) and untreated decay among community-dwelling US adults. Several health-related, social, and behavioral factors emerged as primary predictors of untreated decay. Further research is needed to explore disability types and dental caries determinants.

Impact of oral health conditions on the quality of life of children and adolescents with sickle cell anemia: A cross-sectional study.

Sickle cell anemia (SCA) is the most common hemoglobinopathy in Brazil and worldwide and is part of a group of chronic genetic diseases resulting from abnormalities in the structure of hemoglobin. To evaluate the impact of oral health conditions on the quality of life (QoL) of children and adolescents with SCA. This is a cross-sectional study with a sample of 76 children and adolescents aged 8-14 years. For inclusion, they were required to have a diagnosis of HbSS SCA in their medical records, without a pain crisis or any dental emergency in the last three months. The children and adolescents with SCA were from Hematology and Hemotherapy Center of Maranhão. Demographic characteristics, socioeconomic status, oral hygiene, caries, malocclusion, and oral health-related quality of life (OHRQoL) were assessed. OHRQoL was assessed using the Child Perceptions Questionnaire. Descriptive statistics, Student's t and Mann-Whitney tests were performed (α = 5%). Brown race was the most prevalent for both age groups (8-10 years-63.2% and 11-14 years-57.9%). Predominant monthly family income for both age groups was below $106. Visible plaque and gingival bleeding were higher in children aged 8-10 years. Dental caries significantly impacted the QoL of adolescents through the domain "oral symptom" (p = .031). Malocclusion significantly impacted the QoL of adolescents ("total score," p = .026; "social well-being", p = .045). Oral health impairment negatively affected the QoL of adolescents with SCA.

Oral Health Surveillance System in India: Need and Proposal

Public health surveillance is described as the ongoing systematic collection, analyzing, and interpreting of the data, closely integrated with the transmission of these data to public health practitioners, doctors, and policymakers responsible to prevent and manage disease as well as injury. Both developed and developing nations are becoming aware of the significance of information from efficient surveillance systems for allocating resources and evaluating programs. Over the past few decades, there was a significant change in oral health profiles around the world. Indicators of oral health have improved in many countries, but not in India. An organized system for providing, monitoring, and evaluating oral health care services is needed in India. Draft National oral health policy 2021 has mentioned specific objectives: (a) by 2025, establish baseline data on the burden of oral diseases in the nation, (b) by 2030, the mortality and morbidity from dental and oro-facial diseases reduce to 15%, (c) By 2025, community-based awareness initiatives and practices for oral health will be covered by the healthcare system by a factor of 50%, and by 2030, by a factor of 70%, (d) the creation of an electronic database at district-level on components of the health system by 2025. A well-defined oral health surveillance system in India will serve the purposes (a) to provide standardized recording procedures, standards, and techniques to collect, analyze and interpret the oral health data at the state and central levels (b) to prioritize oral diseases or conditions that will be the focus of oral health surveillance or disease elimination, (c) to digitally monitor and evaluate the progress of nation’s oral health care programs.

Enhancing smile and Altering Thrust using Modified Groper’s Appliance: A Case-Report

Early childhood caries, has a major influence on child’s lifestyle, resulting in child experiencing severe pain, premature loss of teeth, poor nutrition, difficulty chewing, speech, compromised esthetics, development of abnormal oral habits and delay in achieving normal growth and development of child. This paper presents a case report of a Four-year-old child diagnosed with Severe Early Childhood Caries. It explains treatment plan for rehabilitating child's mouth, including caries prevention and restorative procedures using appliances and making special adjustments to a child's feeding habits, combined with maintaining good oral hygiene practices. Early childhood caries is an important oral condition that requires prompt treatment and early intervention. Early diagnosis and awareness of ECC are essential for helping the child maintain a good quality of life.

Assessment of oral health status amongst postal employees of Bhubaneswar city: A cross-sectional study.

Upholding good dental health has wider effects on productivity and performance at work in addition to being crucial for individual well-being. Because it can affect both their personal well-being and productivity at work, post office workers' oral health is therefore a critical issue of concern. Hence, evaluating Bhubaneswar city post office workers' dental health is the study's aim. With the aid of the WHO 2013 oral health assessment form, a cross-sectional study involving 171 regular post office workers was undertaken. Using the Chi-square test and an ANOVA for pertinent variables, the data were analysed using SPSS statistical software version 27.0. Potential confounding variables were adjusted using multiple logistic regression analysis. The survey included a total of 171 post office personnel, of which 76.6% were men and 23.4% were women. The participants' periodontal health revealed that 67.7% had deep periodontal pockets, 18.7% had shallow ones, and 95.3% had bleeding gums. The mean DMFT of the study participants was 4.10 ± 3.149. Among post office workers, tobacco use and oral health conditions represent a crucial junction of variables that call for caution and preventative action.

Analysis of factors related to radiation-induced oral mucositis in patients with head and neck tumors undergoing radiotherapy

ObjectiveTo explore the risk factors of radiation-induced oral mucositis (RIOM) in patients with head and neck tumors undergoing radiotherapy. MethodsA retrospective collection was conducted on patients with head and neck tumors who underwent radiotherapy and chemotherapy in our hospital from April 1, 2015 to April 1, 2019. They were divided into an incidence group (n = 48) and a non-incidence group (n = 76) based on whether RIOM occurred, and relevant data was collected for comparison. ResultsThere were statistically significant differences between the two groups of patients in terms of tumor type, smoking percentage, education level percentage, tumor stage, oral mucosal inflammation stage, radiotherapy dose, mucosal protectants, and oral hygiene condition(P < 0.05); The regression analysis results showed that smoking (OR=1.274, 95 % CI: 1.095–2.007), high-dose radiotherapy (OR=1.223, 95 % CI: 1.098–2.077), and poor oral hygiene (OR=1.367, 95 % CI: 1.024–2.890) were risk factors for RIOM. ConclusionSmoking, high-dose radiotherapy, and poor oral hygiene were risk factors for RIOM in head and neck patients after radiotherapy and chemotherapy.

Oral And Dental Evaluation Of Bone Marrow Transplant Patients: A Retrospective Observational Study

This retrospective observational study aims to evaluate the oral and dental conditions of 100 bone marrow transplant (BMT) patients. The study assessed oral pathologies, including root canal treatments, extractions, squamous cell carcinoma cases, oral prophylaxis procedures, and restorations. The findings provide valuable insights into the oral health challenges faced by BMT patients, emphasizing the need for specialized dental care and preventive measures in this vulnerable population

Fracture Resistance of Space Maintainers Produced Using 3D Printable Materials.

This study aimed to evaluate the fracture resistance of space maintainers (SMs) produced using 3D-printable materials (metal, resin and polyetheretherketone [PEEK]) after thermal aging and compare them with conventional space maintainers. A standardised typodont model for paediatric dentistry was utilised, and band and loop space maintainers were designed digitally using computer-aided design (CAD) technology. Four groups were established: Conventional, 3D printed metal, 3D printed resin, and 3D printed PEEK. Fracture resistance was assessed after 10,000 thermal cycles, simulating oral conditions. Fracture tests were conducted using a universal testing machine, applying vertical force to the band and loop junction until fracture. Statistical analyses were performed using one-way ANOVA and the Tukey HSD test (P<0.05). Although the fracture resistance values showed that metal, resin, and PEEK 3D printed band and loop space maintainers can be acceptable clinically, the permanent resin may be preferable to printable material because of their aesthetic properties.