Background & Objectives: Newborns are often sedated during MRI but sedation itself creates adverse events and the management is more challenging in the MR environment (1). We describe our initial experience with oral 30% glucose administration through a teat during MRI for imaging of newborns. Materials & Methods: Nineteen newborns were assessed retrospectively after institutional research and ethics committee approval. 0.5-1 mL 30% glucose solution was administered orally. The motionless and sleepiness of newborns were evaluated after suckling. If the target conditions was not achieved, 0.5-1 mL increments of glucose was added. After 2 consecutive oral glucose administration the newborns who did not keep motionless or asleep and had motion artefacts were sedated with midazolam. The routine blood glucose level measurement of the newborns after imaging procedures in the ICU was performed for each patient. Results: Fifteen of 19 newborns quietened, kept motionless and slept during the procedure with administration of oral 30% glucose solution. However, 4 of 19 newborns did not keep motionless or asleep after 2 additional dosages of 30% glucose for induction and were needed further sedation. Conclusion: Majority of newborns completed MRI examination with oral 30% glucose administration without a need for sedation. Thereby, we recommend and support the integration of this safe and reliable technique into routine practice for newborns during MRI.