In the process of Nedielnegas-condensate field development flooding of the productive horizon M-4 is observed, which negatively effects reaching the maximum hydrocarbonex traction factor. Experts of Yuliyevskeoil, gas and condensate workshop conducted exploration study of well 3. On the results of this study such mode of the well operation was chosen, which provides periodical gas take-off. During subsequent operation the well stopped. In order to restore its operation, development of the well was carried out and then it was operated again. Due to the growth of the water factor, well operation did not last long. To solve this well flooding problem, works on selective water-isolation were carried out according to the technology developed by Ukrainian Research Institute for Natural Gases. Its essence lies in the formation of impermeable layer of blocking material in reservoir conditions, which provides isolation of the stratum water inflow. The institute experts elaborated the plan according to which the work was conducted in several stages, in particular, supplying foam into the internal cavity of the lift tubes for washing out the sand, pumping blocking solution, pumping chemical reactants and study of the well. On the results of the conducted water-isolation works reduction of the stratum water content in the well was achieved. Individual measurements of the well operation parameters were conducted. Thus, the conducted water-isolation works made it possible to restore the well operation. Technological mode of the well operation that was limited due to the installation of a washer at the wellhead was proposed. In order to prevent premature flooding of the water horizons, an important measure is selection and adherence to the optimal technological mode of the well operation. In the conditions of the water factor growth it is necessary to conduct geophysical studies in order to detect the source of water inflow to the well.