The problem of applying the neural networks for static calibration of measuring systems and for measurand reconstruction is addressed. A multilayered neural network based method for the static calibration of this system is proposed. The functioning of the calibrated measuring system is based on three fiber-optic transducers whose static characteristics are nonmonotonic and significantly influenced by temperature. The applicability of the proposed calibration method is demonstrated in the case under consideration using synthetic and real data. The neural network is designed and implemented in a general purpose microcontroller. In comparison with the spline-based method of calibration, for the same reference data, the proposed method allows obtention of a better quality of calibration and, most important, when calibrated, the multilayered neural network does not require the measurement of temperature for pressure reconstruction.