A fundus image is a two-dimensional pictorial representation of the membrane at the rear of the eye that consists of blood vessels, the optical disc, optical cup, macula, and fovea. Ophthalmologists use it during eye examinations to screen, diagnose, and monitor the progress of retinal diseases or conditions such as diabetes, age-marked degeneration (AMD), glaucoma, retinopathy of prematurity (ROP), and many more ocular ailments. Developments in ocular optical systems, image acquisition, processing, and management techniques over the past few years have contributed to the use of fundus images to monitor eye conditions and other related health complications. This review summarizes the various state-of-the-art technologies related to the fundus imaging device, analysis techniques, and their potential applications for ocular diseases such as diabetic retinopathy, glaucoma, AMD, cataracts, and ROP. We also present potential opportunities for fundus imaging–based affordable, noninvasive devices for scanning, monitoring, and predicting ocular health conditions and providing other physiological information, for example, heart rate (HR), blood components, pulse rate, heart rate variability (HRV), retinal blood perfusion, and more. In addition, we present different types of technological, economical, and sociological factors that impact the growth of the fundus imaging–based technologies for health monitoring.
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