N.N. VASILEVSKII, Z,A. ALEKSANYAN, and S.I. SOROKO Institute of Experimental Medicine, USSR Academy of Medical Sciences, Leningrad Vibration is a widespread form of contact stimulus. Two main hypotheses have been put forward to explain the mechanism of perception of vibration. Some authors consider that specific vibroreceptors exist (1, 2, 95 10). Scott (16), Gray and Matthews {13), Hunt and McIntyre (15), and Hunt (14) have described the high sensitivity of Paccinian corpuscles to vibratory stimulation. The opposite view, i.e., that vibration and pressure are both perceived by the same skin receptors, is also held (8, 12). Bekhterev (2) claimed that vibration may also be perceived by receptors of deep sensation located in the subcutaneous tissue, fascia, ligaments, joint capsules, and muscles. No definite conclusion regarding the mechanism of perception of vibration can be drawn from the literature, nor have the special features of the responses of central (especially cortical) neurons to vibratory stimulation yet been studied. The present investigation was therefore carried out in order to study activation of primary cutaneous afferent fibers of different modalities reacting to constant pressure and to transient light touch, and also activation of various types of cortical neurons in the projection zone of the cutaneous analyzer. Since it has now been established that the development of pathological changes fol- lowing prolonged exposure to vibratory stimulation (1) is reflex in nature, solution of the problems being studied will facilitate understanding of the pathogenesIs of vibration disease. In clinical neurology, changes in sensitivity to vibration are a differential diagnostic sign (6, 11).
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