This work presents a low-power operational amplifier (op-amp) circuit design which optimized and tailored specifically for biomedical circuit application in low power environment. The proposed op-amp design incorporates the folded cascode differential amplifier technique with a low voltage supply 1.2 V, utilizing current biasing, current mirrors, and adopted low-power circuit topologies. AC and DC analysis are carried out to analyse the performance of the proposed design. Extensive simulations executed using industrial standard EDA tool have validated the circuit design, and demonstrated a gain of 70.94 dB, UGBW of 4.90 MHz, GM of 52.70 dB, PM of 82.02 degrees, PSRR of 82.77 dB, CMRR of 100.78 dB, and total power dissipation of only 28.07 mW. Low power consumption is essential for biomedical circuit applications, and the result shows a significant power reduction without compromising other performance parameters. The proposed op-amp circuit design is suitable to be implemented in low-power and high-performance biomedical devices.