Poincare characteristic for reflexive relations (oriented graphs) is defined in terms of homology and is not invariant under transitive closure. Formulas for the Poincare characteristic of products, joins, and bounded products are given. Euler's definition of characteristic extends to certain filtrations of reflexive relations which exist iff there are no oriented loops. Euler characteristic is independent of filtration, agrees with Poincare characteristic, and is unique. One-sided Mobius characteristic is defined as the sum of all values of a one-sided inverse of the zeta function. Such one-sided inverses exist iff there are no local oriented loops (although there may be global oriented loops). One-sided Mobius characteristic need not be Poincare characteristic, but it is when a one-sided local transitivity condition is satisfied. A two-sided local transitivity condition insures the existence of the Mobius function but Mobius inversion fails for non-posets.