Ohio State University Research Articles

Establishing the feasibility of exercise breaks during university lectures.

It is important that principles of laboratory-based studies with implications for academic performance be implemented in naturalistic learning environments to gauge their feasibility. Here, an adaptation of a laboratory-based study of exercise breaks during a single video lecture was implemented during large, in-person lectures at Ohio State University for the duration of a semester. The rationale for this approach was based on findings that research participants who took exercise breaks during a video lecture were more likely to be on task towards the end of the lecture and performed significantly better on a multiple choice exam. The current project had three goals: (1) Establish the feasibility of integrating student-led exercise breaks during in-person lectures in a large university setting (2) Provide practical guidelines for implementing exercise breaks during in-person lectures (3) Provide preliminary evidence of positive effects of exercise breaks in a higher-education setting. One to two student-led exercise breaks (5 min each) were implemented during each 80 min, in-person lecture for the duration of a semester in four upper level Psychology courses with student enrollment ranging from 20 to 93 students (total enrollment = 223 students). Students reported that the exercise breaks were a strength of the courses and a positive experience, including self-reported improvement in attention to lecture content. Self-reported quantitative data indicated that exercise breaks improved attention, increased course enjoyment, and enhanced peer engagement. Compared to other classes, the students preferred exercise breaks during lectures. The current approach establishes the feasibility of integrating exercise breaks in a large, in-person university lecture environment for the duration of a semester with preliminary data indicating a positive impact on attention, engagement, and enjoyment. Practical guidelines for implementing exercise breaks during in-person lectures are provided.

ECR Spotlight – Jai Tiarks

ECR Spotlight is a series of interviews with early-career authors from a selection of papers published in Journal of Experimental Biology and aims to promote not only the diversity of early-career researchers (ECRs) working in experimental biology but also the huge variety of animals and physiological systems that are essential for the ‘comparative’ approach. Jai Tiarks is an author on ‘ Turbidity drives plasticity in the eyes and brains of an African cichlid’, published in JEB. Jai is a PhD candidate in the lab of Dr Suzanne M. Gray at the Ohio State University in Columbus, OH, investigating how human-induced changes to the environment affect sensory systems, specifically by looking at how vision responds to altered aquatic environments in an African cichlid fish.

251 The Appalachian Translational Research Network (ATRN) Newsletter: Supporting Communication and Collaboration among Academic and Community Partners to Improve Health in Appalachia

OBJECTIVES/GOALS: The Appalachian Translational Research Network (ATRN) Newsletter provides a unique platform that facilitates communication among Appalachian-serving CTSAs/CTSIs and partnering academic and community organizations that strengthens research efforts and advances translational science across the region. METHODS/STUDY POPULATION: Published biannually, each ATRN Newsletter features content submitted by ATRN member universities and organizations. Members of the Communications Committee, who represent both CTSA- or non-CTSA- affiliated ATRN member institutions, provide as well as review and edit content for the Newsletter. Regular features include researcher and community member spotlights; funding opportunity announcements; information on upcoming seminars, trainings, and special events; and opportunities for collaborations among partnering ATRN institutions. Complementing regularly scheduled Newsletters, special editions are released as warranted, such as a special COVID-19 focused edition published in 2020. RESULTS/ANTICIPATED RESULTS: First published in 2012, the ATRN Newsletter initially represented founding ATRN institutions, the University of Kentucky and the Ohio State University CTSAs, and a readership of 50. Reflecting ATRN growth that now represents 9 academic centers including NCATS- and IDeA-funded hubs, affiliated universities and partnering organizations, readership has grown to include 500 subscribers from across the U.S. and 3 other countries. With the establishment of the official ATRN website in 2019, the ATRN Newsletter became a prominent addition, providing ATRN members’ access to both new and archived editions, thereby expanding reach and further strengthening critical communication across the Network. DISCUSSION/SIGNIFICANCE: Providing a vehicle for communication that supports ATRN collaborations and networking, the Newsletter is foundational to the success of the ATRN mission to improve health outcomes across Appalachia by fostering collaborative inter-institutional and community-academic research partnerships.

The Impact of Faculty Gender on Resident Evaluations of Faculty Performance in Emergency Medicine.

Gender bias impacts the promotion and tenure of female emergency medicine (EM) physicians and limits their ability to advance in academic rank.Many factors influence the promotion and tenure process including research, evaluations, opportunities for leadership, sponsorship, and mentorship. The goal of this study is to determine if resident evaluations of EM faculty differ by faculty gender. A quantitative analysis was used to examine 14,613 teaching evaluations of faculty by residents at a single academic center (The Ohio State University Wexner Medical Center, Columbus) in the years 2017-2019.Anonymized ratings of male and female faculty on a five-point Likert scale were compared using Fischer's exact test and adjusting for multiple comparisons. Male faculty were more likely to hold the rank of Associate Professor or Professor. When taking both faculty gender and rank into account, male Clinical Instructors and Assistant Professors had significantly higher evaluation scores by residents in the domain of resident autonomy than their female counterparts. Regardless of gender or faculty rank, the majority of faculty received scores greater than four. A significant gender difference was found in resident evaluation scores of faculty in the domain ofresident autonomyat the level of Clinical Instructor and Assistant Professor.Resident autonomy refers to the degree of supervision by faculty which evolves over time and is primarily based on level of training.This is important as it demonstrates a gender difference in scores that could be used to determine faculty compensation and promotion. Evaluation tools used for promotion and tenure of academic faculty should be evaluated for implicit bias and appropriate statistical analysis.

Giving a voice to our silent teachers: Whole body donation from the donor perspective at one donation program in the United States.

Human body donors play a crucial role in anatomical education, research, and clinical skills training, and those interested in anatomical donation may bequeath their bodies to body donation programs (BDPs). The purpose of this study was to evaluate the perspective of body donors on the donation process in order to make recommendations for improvement that align with donor values. A survey was administered via email to 2145 individuals that had enrolled in The Ohio State University's BDP and yielded a 40% response rate. Results showed that a majority of registered donors do not place high importance on detailed consent options during the enrollment process, but do value BDP oversight, such as through the use of an oversight committee to supervise the program. Only 9.1% of donors felt that their loved ones should be permitted to make changes to their consent forms after they have passed. Although 96.2% of participants would allow photos/videos to be taken of their donated bodies, females were significantly less likely to consent to this than males (p = 0.001), as well as less likely to allow their donations to be utilized for anatomy outreach (p = 0.023). Racial minorities were significantly less trusting of the university to treat their donation with dignity and respect compared to White registrants (p = 0.034). Suggestions for improving BDP protocols include the implementation of an annual newsletter for registrants, improving methods to spread awareness about donation, increasing transparency during the consent process, and creating resources for donors' families.

Abstract 2213: Vaping, smoking and lung cancer: A case-control study

Abstract Introduction: Nicotine exposure through the use of electronic delivery systems (vaping) has been found to elevate the risk of certain conditions of the lungs, e.g., vaping associated lung injury. However, the potential impact of vaping on lung cancer risk remains largely unexplored. We, therefore, examined the association of vaping and cigarette smoking with lung cancer risk in a case-control study conducted at The Ohio State University in Columbus, Ohio. Methods: Medical records examined from the James Cancer Hospital and Solove Research Institute revealed 4,975 cases with newly diagnosed, pathologically confirmed lung cancer during 2013-2021. These cases were compared to 27,294 controls without cancer that were group-matched on a 5:1 ratio to cases by age, gender, race and year of ascertainment. Descriptive statistics were calculated, and logistic regression analyses were performed to assess the associations between vaping, smoking and lung cancer. Results: The lung cancer cases in this study were 55% male, 88% white, with mean age at diagnosis of 62 years. The adjusted odds ratio (OR) for individuals who reported vaping and smoking was OR=21.1 (95% CI=17.1, 26.1) versus OR=6.3 (95% CI=5.8, 6.8) for smoking only. Estimates for gender and histologic cell type of lung cancer, e.g., pulmonary adenocarcinoma, squamous cell carcinoma and small cell carcinoma, were consistently over threefold higher for vaping and smoking compared to smoking only (p<0.001), and the vaping effect persisted even after adjustment for comorbidities, COPD and cardiovascular disease. Conclusion: Adjusted estimates of odds ratios (OR) revealed over threefold higher risk of lung cancer among individuals who had vaped and smoked compared to individuals who only smoked. Our results suggest that the addition of vaping to smoking greatly accelerates the risk of developing lung cancer. Future studies are needed to further confirm these results. Citation Format: Marisa A. Bittoni, David Carbone, Randall Harris. Vaping, smoking and lung cancer: A case-control study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 2213.

Abstract 3404: Body weight trajectory among patients with non-small-cell lung cancer receiving immune checkpoint inhibitors

Abstract Objectives: Body weight is an important prognostic factor in patients with lung cancer. As immunotherapy involves toxicities, body weight may be affected during the treatment course. The objective of this study is to examine the trajectory of weight changes at 180 and 365 days after the initiation of immune checkpoint inhibitors (ICIs) among patients with NSCLC. Methods: Retrospective chart review and data extraction were performed among patients receiving ICIs at the Ohio State University Comprehensive Cancer Center between 2015 and 2021. Patients with NSCLC were included in this study if their initial treatment entailed a PD-1/PD-L1 ICI), either alone or in combination with chemotherapy/targeted cancer drugs, and if they also had their body weights recorded on ICI initiation and 180 days after (± 30 days) treatment initiation. A subset of these patients who had body weight data on day 365 of ICI initiation were included in additional analysis. Percentages of change in body weight relative to pre-ICI were calculated ([weight at 180 or 360 days minus pre-ICI weight] divided by pre-ICI weight x 100%) and examined by treatment regimen and pre-ICI body mass index (BMI) using t-tests. A sensitivity analysis was performed by excluding 11 patients with cachexia defined by the presence of ICD-9 (799.4) or 10 (R64) codes in their medical records. Results: A total of 554 patients with NSCLC received any ICI; 139 patients met the inclusion criteria, of which 96 had body weight data on day 365. The mean age of diagnosis was 63.8 (SD=10.1); 80% were White and 18.7% were Black. The median time on ICI was 195 days (inter-quartile range, 55-392 days) among patients with ICI only and 255 days (inter-quartile range, 126-479 days) among patients with ICI combined with chemotherapy or targeted cancer drugs. Among patients receiving ICI only, body weight increased among those with normal weight (BMI <25.0; mean change = +7.57%, P=0.013) but decreased among those classified as overweight (BMI = 25.0 to 29.9; −5.2%, P=0.037) or obese (BMI ≥30; −6.5%, P=0.025). Decreases in weight were also observed for patients with obesity and receiving a combined treatment (−9.65%, P=0.043). After one year of treatment, weight changes among patients receiving ICI only remained significant in the normal weight group (+15.6%, P=0.007), but not among patients with other BMIs and treatment regimens. These associations remained similar after excluding the patients with cachexia. Conclusions: Body weight change during ICI therapy may vary by treatment regimen and pre-ICI BMI among patients with NSCLC. Whether the weight changes are related to toxicities and survival warrants further research to shed light on weight management, ICI efficacy, and prevention of treatment-related adverse events. Funding: The study was in part funded by NIH/NCI R37CA248371, OSUCCC CCSG P30CA016058, and Pelotonia Institute for Immuno-Oncology (PIIO) at OSUCCC. Citation Format: Ting-Yuan David Cheng, Ben Kinder, Rand T. Akasheh, Cuthbert Mario Mahenge, Carolyn J. Presley, Peter G. Shields, Xuan Nguyen, Aditi Shendre, Zihai Li, Lang Li. Body weight trajectory among patients with non-small-cell lung cancer receiving immune checkpoint inhibitors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3404.

Multiphase entrepreneurship: An academic reflection

Teaching, research, and service have traditionally been the common denominators of faculty professional responsibilities at academic institutions. In contrast, entrepreneurship has historically been considered separate from these responsibilities, often viewed as an aspirational goal above and beyond the standard expectations. This situation arises, in part, from the fact that most academic environments do not usually offer the conditions conducive for faculty to commercialize their ideas through entrepreneurship. Yet, integrating entrepreneurship with academic duties offers a unique opportunity to enhance the impact of one's work beyond the scholarly community, aligning well with the current public-facing and, the innovation-driven landscape of higher education. For faculty to succeed in academic entrepreneurship, balancing and harmonizing entrepreneurial goals with traditional responsibilities as members of the university is crucial. Furthermore, faculty need to understand the product market, the related tech-economic factors, the importance of industrial and academic partnerships, and the required financial and workforce support to achieve successful entrepreneurship outcomes. In this article, I illustrate that embracing entrepreneurship not only complements but also enriches traditional academic duties, offering a means to apply research in addressing real-world challenges. Speaking from personal experience, I recount how I set the goal early in my academic career to make entrepreneurship a significant part of my professional life, how this decision was informed by my research on multiphase reaction engineering, an area replete with examples of successful industrial processes, and how this guided my path forward in developing commercial processes of my own. I aim to elucidate the challenges of academic entrepreneurship through the lens of my entrepreneurial efforts. Through my journey spanning four decades, I highlight the rewards of academic entrepreneurship, including enhanced research applicability, increased funding opportunities, and the personal satisfaction of seeing one's work contribute to societal advancement. This journey, punctuated and highlighted with a multitude of opportunities, challenges, and experiences, has yielded several industrial processes, made possible by the support of strong, capable teams of creative and dedicated graduate students and post-doctoral research associates. I have also benefited considerably from the support of the Ohio State University (OSU) in matters such as patent filing, licensing, and startup spin-offs. The strength of the industrial partnerships I have played a part in forging has facilitated the potential realization of commercializing selected technologies—the ultimate goal of academic entrepreneurship. This article aims to demystify the challenges of academic entrepreneurship and inspire my academic colleagues to consider how they, too, can weave entrepreneurial endeavors into the tapestry of their professional careers. The journey of academic entrepreneurship is not only about achieving commercial success but also about synergistically enriching one's teaching and research goals with the dynamism of real-world problem-solving in ways that make a lasting impact on both academia and industry.

Using Multimedia Dissection Videos to Supplement Learning of Veterinary Anatomy in the COVID Era and Beyond: Student Perceptions and Benefits

Anatomy is a foundation for veterinary medical education, yet its teaching has traditionally posed an academic challenge to students. Anatomy is a three-dimensional (3D) subject that students are often expected to learn using one- or two-dimensional learning resources. Visualization of structures and the transfer of images to animal specimens can impede knowledge acquisition and student confidence. As a response to the COVID-19 pandemic, the first-year anatomy course (Anatomy I) at The Ohio State University College of Veterinary Medicine was delivered virtually in Autumn 2020. Instructors were challenged to create equivalent learning experiences without face-to-face interaction and cadaveric access. Fortunately, multimedia dissection videos were in production and supplemented students’ learning of anatomic structures and dissection techniques. Videos included complete narration, explanations, diagrams, labels, and self-check opportunities. To evaluate the perceived effectiveness of the videos on student learning, the Anatomy I teaching team surveyed all first-year veterinary students following the course. Of the 104 students (64%) who completed the survey, 101 (97%) agreed or strongly agreed that the videos helped solidify their anatomy knowledge, skills, and understanding. The most helpful video characteristics included the demonstration of dissection techniques on a cadaver and the visualization of structures on 3D specimens. Students also appreciated the ability to review content at their own pace/convenience, a feature inherent to recorded (asynchronous) video-based instruction. These data suggest that video-based instruction may effectively supplement students’ learning of veterinary anatomy and improve the transfer of knowledge, particularly when other forms of direct instruction are inaccessible.

The Effects of Repetitive Head Impact Exposure on Mental Health Symptoms Following Traumatic Brain Injury.

This study aimed to characterize the types and timing of repetitive head impact (RHI) exposures in individuals with moderate to severe traumatic brain injury (TBI) and to examine the effects of RHI exposures on mental health outcomes. TBI Model Systems National Database. 447 patients with moderate to severe TBI who reported RHI exposure between 2015 and 2022. Secondary data analysis. RHI exposures reported on the Ohio State University TBI Identification Method (OSU TBI-ID) were characterized by exposure category, duration, and timing relative to the index TBI. Mental health outcomes were evaluated at the 5-year follow-up assessment using the Patient Health Questionnaire-9 (PHQ-9) for depression symptoms and the Generalized Anxiety Disorder-7 (GAD-7) for anxiety symptoms. The majority of RHI exposures were sports-related (61.1%), followed by other causes (20.8%; including falls), repetitive violence/assault (18.8%), and military exposures (6.7%). Males predominantly reported sports and military exposures, while a larger proportion of females reported violence and falls. Sports exposures were most common before the index TBI, while exposures from falls and violence/abuse were most common after TBI. RHI exposures occurring after the index TBI were associated with higher levels of depression (β = 5.05; 95% CI, 1.59-8.50) and anxiety (β = 4.53; 95% CI, 1.02-8.05) symptoms than exposures before the index TBI. The findings emphasize the need to consider RHI exposures and their interaction with TBI when assessing mental health outcomes. Understanding the prevalence and challenges associated with RHI post-TBI can inform targeted interventions and improve the well-being of individuals with TBI. Preventive measures and ongoing care should be implemented to address the risks posed by RHI, particularly in individuals with prior TBI, especially surrounding fall and violence/abuse prevention.

Carotid Blowout after Standard Fractionation Re-irradiation: The Ohio State University Experience

Carotid Blowout after Standard Fractionation Re-irradiation: The Ohio State University Experience

Abstracts from the 2023 Occupational Therapy Summit of Scholars Conference, Ohio State University, June 22-24, 2023

Abstracts from the 2023 Occupational Therapy Summit of Scholars Conference, Ohio State University, June 22-24, 2023

Prevalence of Electrographic Seizures in Hospitalized Patients With Altered Mental Status With No Significant Seizure Risk Factors Who Underwent Continuous EEG Monitoring: A Retrospective Study.

The objective of this study is to evaluate the prevalence of electrographic seizures in hospitalized patients with altered mental status and no significant risk factors for seizures. We retrospectively reviewed over a six-year period (2013-2019) the medical records of all adults admitted at Ohio State University Wexner Medical Center (OSUWMC), who underwent continuous electroencephalography (cEEG) monitoring for > 48 hours. Our primary objective was to identify the prevalence of electrographic seizures in patients with altered mental status and no significant acute or remote risk factors for seizures. A total of 1966 patients were screened for the study, 1892 were excluded (96.2%) and 74 patients met inclusion criteria. Electrographic seizures were identified in seven of 74 patients (9.45%). We found a significant correlation between electrographic seizures and a history of hepatic cirrhosis, n= 4 (57%), (p=0.035), acute chronic hepatic failure during admission, 71% (n=5), (p=0.027), and hyperammonemia (p =0.009). In this retrospective study of patients with altered mental status and no significant acute or remote risk factors for seizures who underwent cEEG monitoring for > 48 hours, electrographic seizures were identified in 9.45%. Electrographic seizures were associated with hepatic dysfunction and hyperammonemia. Based on our results, cEEG monitoring should be considered in patients with altered mental status and hepatic dysfunction even in the absence of other seizure risk factors.

Neurobehavioral Symptoms in Spanish-Speaking Individuals With Subconcussive Injuries.

To examine whether exposure to high-risk events causing injury to the head or neck has an effect on neurobehavioral symptoms in the absence of an alteration of consciousness in Spanish-speakers. Web-based survey. Seven hundred forty-eight individuals from Spain and Latin America, aged 18 to 65 years, with 10 years or more of education. Thirty-nine participants failed quality checks and were excluded. Seven hundred nine participants were included in the analyses. Cross-sectional study. Subconcussive exposure was defined as endorsing exposure to one or more high-risk scenarios in the absence of any alteration of consciousness. Three injury groups were derived: No Head Injury, Subconcussive Exposure, and traumatic brain injury (TBI). The Subconcussive Exposure group was further divided into Single and Multiple Exposures. Two analyses were conducted: the effect of lifetime exposure to injury (No Head Injury, Subconcussive Exposure, TBI) on neurobehavioral symptoms; the effect of Subconcussive Exposure Frequency (No Head Injury, Single Exposure, Multiple Exposures) on neurobehavioral symptoms. Spanish Ohio State University Traumatic Brain Injury Identification Method Self-Administered-Brief (OSU TBI-ID SAB); Neurobehavioral Symptom Inventory (NSI). There was a significant effect for Injury group on the NSI partial eta-squared (η p2 = 0.053) and a significant effect of Exposure Frequency group on the NSI (η p2 = 0.40). Individuals with subconcussive exposures reported significantly more neurobehavioral symptoms than those with no history of head injury and significantly less symptoms than those with TBI. Individuals with multiple subconcussive exposures reported significantly more neurobehavioral symptoms than those with single and no exposure. This research expands the utility of the OSU-TBI-ID SAB as a lifetime TBI history assessment tool to one capable of evaluating subconcussive exposure dosing effects in Spanish-speakers. Such an index may facilitate establishment of subconcussive exposure prevalence rates worldwide, leading to improved understanding of the chronic effects of high-risk exposures.

Production of OSU G5P[7] Porcine Rotavirus Expressing a Fluorescent Reporter via Reverse Genetics.

Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in infants and the young of many economically important animals. Although vaccines against porcine rotavirus exist, both live oral and inactivated, their effectiveness in preventing gastroenteritis is less than ideal. Thus, there is a need for the development of new generations of porcine rotavirus vaccines. The Ohio State University (OSU) rotavirus strain represents a Rotavirus A species with a G5P[7] genotype, the genotype most frequently associated with rotavirus disease in piglets. Using complete genome sequences that were determined via Nanopore sequencing, we developed a robust reverse genetics system enabling the recovery of recombinant (r)OSU rotavirus. Although rOSU grew to high titers (~107 plaque-forming units/mL), its growth kinetics were modestly decreased in comparison to the laboratory-adapted OSU virus. The reverse genetics system was used to generate the rOSU rotavirus, which served as an expression vector for a foreign protein. Specifically, by engineering a fused NSP3-2A-UnaG open reading frame into the segment 7 RNA, we produced a genetically stable rOSU virus that expressed the fluorescent UnaG protein as a functional separate product. Together, these findings raise the possibility of producing improved live oral porcine rotavirus vaccines through reverse-genetics-based modification or combination porcine rotavirus vaccines that can express neutralizing antigens for other porcine enteric diseases.

Quality of obturation and the behavior of children treated under nitrous oxide conscious sedation: A double-blinded split-mouth randomized clinical trial

Abstract Aim: Our aim is to assess the quality of obturation and behavior of the children treated with and without nitrous oxide sedation and also to investigate the association between the quality of obturation and the behavior of children. Materials and Methods: A double-blinded split-mouth randomized clinical trial was conducted in 60 teeth. A total of 30 children aged 4–8 years in need of pulpectomy in bilateral mandibular molars were selected. On the first appointment, the children were assigned to protocol A, where the pulpectomy was performed without nitrous oxide inhalation sedation (NOIS). In the second visit, the children were allocated to protocol B, where pulpectomy was done in the contralateral molar under NOIS. The obturation quality and behavior of the children were graded according Coll and Sadrian criteria and Ohio State University Behavior Rating Scale, respectively. The data were assessed with descriptive statistics, Chi-square test, and Wilcoxin signed-rank test. Results: The quality of obturation and the behavior of the children were significantly better under conscious sedation (P = 0.000). Also, there was a significant association noted between the behavior of the children and quality of obturation (P = 0.0.012). Children exhibiting quiet behavior favored optimal fill, while in children showing cry alone or struggle , it was more of under-fill. In children showing both struggle and cry, more of over-fill pattern of obturation was noticed. Conclusion: Nitrous oxide sedation enhances the obturation quality and children’s behavior. Furthermore, there is a clear association between children’s behavior and obturation quality, regardless of whether nitrous oxide sedation is used or not.

Head injury and associated disability in adults undergoing pre-sentencing assessment by criminal justice social work

Although evidence indicates that head injury (HI) is prevalent in prisoners, little is known about HI in defendants during the Court process. This study assesses history of HI and persisting sequelae in defendants undergoing Criminal Justice Social Work (CJSW) assessment for Court.A cross sectional, between subjects design was used. HI history was assessed using the Ohio State University TBI Identification-Method and disability with the Glasgow Outcome Scale-Extended in 46 adult defendants undergoing a CJSW assessment in Scotland. Assessments of mental health, cognitive function, effort on tests and dysexecutive behaviour were also carried out. Comparisons were made between defendants with and without significant HI.Significant HI (SHI) was found in 33/46 (72%) participants and 39% (13/33) of these had persisting disability. Those with SHI were more likely to have moderate-severe mental health difficulties, problematic alcohol or drug use and impairment on the Dysexecutive Questionnaire. Group differences were not found on cognitive tests or in offending history. No CJSW report identified HI.Disability, psychological distress, dysexecutive behaviour and potentially harmful substance use are more common in defendants with SHI. Training and a screening process for HI in CJSW assessments is needed to inform Court disposals and interventions.

Court rules against plaintiffs

Case name: Meola, et al. v. The Ohio State University, No. 23AP‐180 (Ohio Ct. App. 10/19/23).

Pseudo-differential operators on the circle, Bernoulli polynomials

We show how the classical polylogarithm function Lis(z)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ extrm{Li}_s(z)$$\\end{document} and its relatives, the Hurwitz zeta function and the Lerch function are all of a spectral nature, and can explain many properties of the complex powers of the Laplacian on the circle and of the distribution (x+i0)s\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$(x+i 0)^s$$\\end{document}. We also make a relation with a result of Keiper [Fractional Calculus and its relationship to Riemann’s zeta function, Master of Science, Ohio State University, Mathematics (1975)].

Cretaceous–Palaeogene lobsters, Hoploparia stokesi (Weller, 1903), from Antarctica: historical review, and transfer of specimens from the United States Polar Rock Repository

The nephropid lobster Hoploparia stokesi (Weller 1903a) is widely distributed among the islands of the Antarctic Peninsula, where it occurs in strata of Cretaceous (Campanian–Maastrichtian) to Palaeogene (Paleocene) age. Specimens of H. stokesi collected during expeditions in the 1980s that were in the collection of the United States Polar Rock Repository at The Ohio State University have been transferred to the Orton Geological Museum, joining other geological collections from Antarctica. Some of the transferred specimens are voucher specimens described or illustrated in earlier published work.