The article is devoted to the study of the peculiarities of exercising the functions of the Prosecutor’s Office of Ukraine in the context of ensuring the national security of the State in the current conditions. Attention is focused on the procedural guidance of pre-trial investigation and support of public prosecution in court in criminal proceedings on crimes against the foundations of national security of Ukraine. The author notes that the main regulatory documents defining the main directions of the state policy in the field of national security do not mention the prosecutor’s office and its activities. At the same time, the work demonstrates that, as a key criminal justice body, the prosecutor’s office is actively involved in ensuring the national security of Ukraine within its competence. The author emphasizes the importance of the prosecutor’s office’s coordination activities in the area of combating crime, primarily crimes against the foundations of national security of Ukraine, cybercrime, corruption criminal offenses, offenses in the budgetary and economic security spheres, as well as organized crime, which have a destructive impact on the proper functioning of the national security of the State. The author provides examples of skillful use of coordination powers by the heads of individual prosecutor’s offices, which helped to orient law enforcement agencies to further effective counteraction to separatism, encroachment on the territorial integrity and inviolability of the State and other crimes against the foundations of national security of Ukraine. The author emphasizes the need to improve the mechanisms of interaction between the prosecutor’s office and other law enforcement agencies, which is crucial for a comprehensive approach to protecting national interests and citizens’ rights, which is the basis of a strong and stable state. The author substantiates the importance of timely and high-quality coverage of the work of the prosecutor’s office in the area of ensuring the national security of Ukraine using the capabilities of modern communication tools, such as the official Telegram channel of the Prosecutor General’s Office, the official pages of the Office on Facebook, Twitter and YouTube.