The glandular odontogenic cyst (GOC) is a rare cyst that was rst described in 1988 as a distinct entity. This lesion can occur in either jaw and is a rare developmental odontogenic cyst that resembles several other odontogenic lesions. However, GOCs have non-specic clinical and radiographic ndings, and diagnosing them can be very difcult given their rarity. Furthermore, GOCs may be difcult to diagnose because they have overlapping histologic features with other intraosseous lesions, such as the lateral periodontal cyst and its botryoid variant, and the dentigerous cyst with metaplastic changes. In this study, we report a new case of GOC in a 42-year-old female patient and review previous cases reported in the literature. We discuss the different kinds of features which will help a clinician distinguish GOC from other lesions.