Octahedral Coordination Environment Research Articles

Synthesis, X-ray structural characterization, and catalytic property of binuclear oxidovanadium(V) complex with 2,4-dibromo-6-(5-methylamino-[1,3,4]thiadiazol-2-yl)phenol

ABSTRACTA novel binuclear oxidovanadium(V) complex [V2O2(μ-O)L2(OEt)2], where L is the deprotonated form of 2,4-dibromo-6-(5-methylamino-[1,3,4]thiadiazol-2-yl)phenol (HL), was prepared by the reaction of 2-(3,5-dibromo-2-hydroxybenzylidene)-N-methylhydrazinecarbothioamide (HL’) and VO(acac)2 in ethanol. The ligand L’ underwent a cyclization during the coordination, to form a new ligand L. Structure of the complex was characterized by physicochemical methods and single-crystal X-ray determination. Crystal of the complex crystallizes in hexagonal space group R-3, with a = b = 33.302(3) Å, c = 15.308(2) Å, α = β = 90°, γ = 120°, V = 14702(3) Å3, Z = 18, R1 = 0.0823, wR2 = 0.2064, S = 1.011. X-ray analysis indicates that the V atom in the complex is in an octahedral coordination environment, constructed by the phenolate O and thiadiazol N atoms of L, one oxido O atom, one bridging O atom, and one deprotonated ethanol O atom. The distance between the two V atoms is 3.365(1) Å. The complex has an effective catalytic property for the oxidation of several olefins.

Cobalt(II) and nickel(II) complexes with N-benzyl- and N-(p-nitrobenzyl)iminodiacetic acids. Structural and vibrational spectroscopic characterization and DFT study

The reactions of N-benzyliminodiacetic acid (BnidaH2) and N-(para-nitrobenzyl)iminodiacetic acid (p-NO2BnidaH2) with cobalt(II) and nickel(II) acetate in aqueous solutions were performed. Three new complexes [Co(Bnida)(H2O)3]·H2O (1a·H2O), [Co(p-NO2Bnida)(H2O)3]·½H2O (2a·½H2O) and [Ni(p-NO2Bnida)(H2O)3]·½H2O (2b·½H2O) were prepared and characterized by infrared spectroscopy and thermal analysis (TG/DTA). The molecular and crystal structures of 1a·H2O and 2b·½H2O were determined by X-ray crystallography. The octahedral coordination environments around the Co(II) ion in 1a and Ni(II) ion in 2b consist of an O,N,O′-tridentate N-arylalkyliminodiacetate ion and three water molecules, resulting in the formation of fac-isomers in both cases. The molecular geometry and infrared spectra of these three complexes, together with previously synthesized and characterized complex [Ni(Bnida)(H2O)3]·H2O (1b·H2O) are studied by DFT calculations using BP86/6-311G(d,p) and mPW1PW91/6-311G(d,p) computational model.

Crystal structure of ammonium/potassium trans-bis-(N-methyl-iminodi-acetato-κ(3) O,N,O')chromate(III) from synchrotron data.

The structure of the title compound, [(NH4)0.8K0.2][Cr(C5H7NO4)2] (C5H7NO4 is methyl-iminodi-acetate; mida), has been determined from synchrotron data. The Cr(III) atom is located on a centre of symmetry and is coordinated by two N atoms and four O atoms of two facially arranged tridentate mida ligands, displaying a slightly distorted octa-hedral coordination environment. The Cr-N and mean Cr-O bond lengths are 2.0792 (14) and 1.958 (14) Å, respectively. The cation site is located on a twofold rotation axis and shows occupational disorder, being occupied by ammonium and potassium cations in a 0.8:0.2 ratio. In the crystal, inter-molecular hydrogen bonds involving the N-H groups of the ammonium cation as donor and the two non-coordinating O atoms of the carboxyl-ate group as acceptor groups consolidate the three-dimensional packing.

Synthesis and crystal structure determination of cobalt(II) mixed-ligand complex containing 1,10-phenanthroline and 5-(2-carboxybenzyloxy)isophthalic acid: Their biological evaluation viz. DNA/protein binding profile, pBR322 DNA cleavage activity

New metal-based cancer chemotherapeutic agent Co(II) complex of the type{[Co(Me2Phen)(o-cbiaH)(H2O)2]·H2O} (1) was synthesized from ligand 5-(2-carboxybenzyloxy)isophthalic acid (o-cbiaH3) and thoroughly characterized by spectroscopic and single crystal X-ray diffraction method. Complex 1 crystallizes in a slightly distorted octahedral CoN2O4 coordination environment. In vitro DNA binding studies of ligand and complex 1 with CT DNA were carried out by using biophysical techniques viz electronic absorption and fluorescence spectral studies which indicated that 1 binds to DNA more avidly as compared to ligand via electrostatic binding mode. Complex 1 shows significant DNA photo cleavage activity through the formation of hydroxyl radicals via photo-redox pathway. The affinity of 1 towards HSA was also investigated by the fluorescence spectroscopic technique and 3D scan measurements revealing that 1 quench the fluorescence intensity of HSA more strongly than o-cbiaH3. Furthermore, magnetic drug targeting shows the accumulation of complex 1 in the target site under the influence of an externally applied magnetic force.

Ion Environments in Mn(2+)-Doped Polyelectrolyte Complexes: Dilute Magnetic Saloplastics.

Amorphous hydrated complexes of the polyelectrolytes poly(styrene sulfonate) (PSS) and poly(diallyldimethylammonium) were doped with the spin-5/2 ion Mn(2+). X-band electron paramagnetic resonance (EPR) measurements of the Mn(2+) spins within these stoichiometric polyelectrolyte complexes (PECs) revealed an octahedral coordination environment, similar to that observed in aqueous solutions of Mn(2+). This octahedral symmetry of the [Mn(H2O)6](2+) complexes, observed in fully hydrated PECs, is somewhat distorted because of the wide range of ion pairs possible with the sulfonate group on PSS. As the Mn(2+) concentration was increased, the linewidths broadened, indicating the dominance of dipolar broadening over exchange narrowing in determining the linewidths; that is, any exchange narrowing was masked by the large dipolar broadening. The calculated linewidths were used to estimate the strengths of the dipolar interactions, and hence the distances between the Mn(2+) spins, on the basis of a simple model of regularly spaced spins. The distances calculated by this method were roughly comparable to the geometric average distances calculated on the basis of the Mn(2+) concentrations and densities of the doped PEC samples. From a comparison of their EPR spectra, the ion environments in the doped, fully hydrated PECs were found to be similar to those in hydrated classical ion exchange resins. EPR spectra before and after drying of the PECs indicate the replacement of octahedrally coordinated water by oxide anions from the polyanion chain and the corresponding loss of the symmetric environment of Mn(2+) ions.

Crystal structure of bis-[4-(di-methyl-amino)-pyridinium] aqua-bis-(oxalato)oxidovanadate(IV) dihydrate.

The title organic-inorganic hybrid salt, (C7H11N2)2[V(C2O4)2O(H2O)]·2H2O, shows a distorted octa-hedral coordination environment for the vanadium(IV) atom in the anion (point group symmetry 2), with four O atoms from two symmetry-related chelating oxalate dianions and two O atoms in trans configuration from a coordinating water mol-ecule and a terminal vanadyl O atom. In the crystal, (001) layers of cations and anions alternate along [001]. The anionic layers are built up by inter-molecular O-H⋯O hydrogen bonds involving the coordinating and solvent water mol-ecules. The cationic layers are linked to the anionic layers via N-H⋯O hydrogen bonds between the pyridinium group and the non-coordinating O atoms of the oxalate group. The 4-(di-methyl-amino)-pyridinium cations are also engaged in π-π stacking with their anti-parallel neighbours [centroid-to-centroid distance = 3.686 (2) Å]. Considering all supra-molecular features, a three-dimensional network structure is accomplished.

Co(III) and Ni(II) complexes of an anthracene appended aroyl hydrazone: Synthesis, crystal structures, DNA binding and catecholase activity

The Co(III) and Ni(II) complexes [Co(L2)2(bpy)]Cl (1) and [Ni(L2)2(phen)] (2) (where L2 is a monoanionic bidentate hydrazone ligand and bpy=2,2′-bipyridine, phen=1,10-phenanthroline) have been synthesized and characterized by infra-red, UV–Vis, ESI-MS spectroscopies and elemental analyses. Complexes 1 and 2 were structurally characterized by single crystal X-ray diffraction. Structural analysis reveals a distorted octahedral coordination environment around the metal center with an MN4O2 chromophore [M=Co(III) and Ni(II)], with the hydrazone ligand acting as a monoanionic bidentate N,O-donor. Binding of complexes 1 and 2 with calf thymus DNA (CT-DNA) was investigated by UV–Vis absorption, fluorescence spectroscopy and viscosity measurements. Complex 1 shows excellent catecholase mimicking activity with 3,5-di-tert-butylcatechol (3,5-DTBCH2) as the substrate. Kinetic measurements suggest the rate of catechol oxidation follows saturation kinetics with respect to the substrate and the kcat value was found to be quite high, with a value of 1.00×105h−1.

Synthesis and structure of a new ternary monocopper(II) complex containing mixed ligands of 2,2′‐diamino‐4,4′‐bithiazole and picrate:in vitroanticancer activity, molecular docking and reactivity towards DNA

A new ternary monocopper(II) complex with co‐ligands of 2,2′‐diamino‐4,4′‐bithiazole (dabt) and picrate (pic), namely [Cu(dabt)(pic)2], has been synthesized and characterized using elemental analyses, molar conductance measurements, infrared and electronic spectral studies and single‐crystal X‐ray diffraction. The crystal structure analyses revealed that the copper(II) ion has a {CuN2O4} distorted octahedral coordination environment. The hydrogen bonding interactions contribute to a three‐dimensional supramolecular structure in the crystal. The reactivity towards herring sperm DNA showed that the copper(II) complex can interact with DNA in the mode of intercalation. The molecular docking of the complex with DNA sequence d(ACCGACGTCGGT)2demonstrated that the copper(II) complex is stabilized by hydrogen bonding interaction. Thein vitroanticancer activities suggested that the copper(II) complex is active against selected tumor cell lines. The effects of the two co‐ligands in the copper(II) complex on DNA‐binding events andin vitroanticancer activity are preliminarily discussed. Copyright © 2016 John Wiley & Sons, Ltd.

Chromium(III) complexes with 1,2,4-diazaphospholide and 2,6-bis(N-1,2,4-diazaphosphol-1-yl) pyridine ligands: synthesis, X-ray structural characterization, EPR spectroscopy analysis, and magnetic susceptibility studies

Abstract Three chromium(III) 1,2,4-diazaphospholide complexes were prepared: 3,5-di-tert-butyl-1,2,4-diazaphospholide chromium(III) dichloride [(η 2-3,5-tBu2dp)Cr(THF)2Cl2] (1), 3,5-di-phenyl-1,2,4-diazaphospholide chromium(III) dichloride [(η 2-3,5-Ph2dp)Cr(THF)2Cl2] (2), and 2,6-bis(N-1,2,4-diazaphosphol-1-yl)pyridine chromium(III) trichloride {[2,6-bis(N-1,2,4-diazaphosphol-1-yl)pyridine]CrCl3} (3). X-ray diffraction analysis has shown that these six-coordinate complexes each have a pseudo-octahedral configuration. Electron paramagnetic resonance (EPR) spectroscopy data for complex 1 for the paramagnetic S = 3/2 system (d 3 electron configuration) confirm a Cr(III) center in the octahedral coordination environment. The magnetic susceptibility of complex 1 followed the Curie–Weiss law well between 25 and 300 K. The magnetic moment of 1 was found to be close to the spin-only magnetic moment expected for three unpaired electrons (3.87 μB).

Crystal structure of catena-poly[[(dimethyl sulfoxide-κO)(pyridine-2,6-di-carboxyl-ato-κ(3) O,N,O')nickel(II)]-μ-pyrazine-κ(2) N:N'

The title coordination polymer, [Ni(C7H3NO4)(C4H4N2)(C2H6OS)] n , consists of [010] chains composed of Ni(II) ions linked by bis-monodentate-bridging pyrazine mol-ecules. Each of the two crystallographically distinct Ni(II) ions is located on a mirror plane and is additionally coordinated by a dimethyl sulfoxide (DMSO) ligand through the oxygen atom and by a tridentate 2,6-pyridine-di-carb-oxy-lic acid dianion through one of each of the carboxyl-ate oxygen atoms and the pyridine nitro-gen atom, leading to a distorted octa-hedral coordination environment. The title structure exhibits an inter-esting complementarity between coordinative bonding and π-π stacking where the Ni-Ni distance of 7.0296 (4) Å across bridging pyrazine ligands allows the pyridine moieties on two adjacent chains to inter-digitate at halfway of the Ni-Ni distance, resulting in π-π stacking between pyridine moieties with a centroid-to-plane distance of 3.5148 (2) Å. The double-chain thus formed also exhibits C-H⋯π inter-actions between pyridine C-H groups on one chain and pyrazine mol-ecules on the other chain. As a result, the inter-ior of the double-chain structure is dominated by π-π stacking and C-H⋯ π inter-actions, while the space between the double-chains is occupied by a C-H⋯O hydrogen-bonding network involving DMSO ligands and carboxyl-ate groups located on the exterior of the double-chains. This separation of dissimilar inter-actions in the inter-ior and exterior of the double-chains further stabilizes the crystal structure.

Catena-Poly[[[[bis(pyridin-2-yl-κN)amine]zinc(II)]-μ2-(2E,4E)-hexa-2,4-dienedioato-κ4O1,O1′:O6,O6′] monohydrate

In the title compound, {[Zn(C6H4O4)(C10H9N3)]·H2O}n, the di(pyridin-2-yl)amine (dpa) ligands chelate the ZnIIions, forming [Zn(dpa)]2+units which are connected by two independent bridging muconate [(2E,4E)-hexa-2,4-dienedioate] ligands to form chains. A crystallographic inversion centre is located at the mid-point of the central C—C bond of each muconate ligand. The carboxylate groups of the muconate ligands bridge the ZnIIions in asymmetric chelating modes. The ZnIIion is coordinated by four O atoms of two chelating carboxylate groups and two pyridyl N atoms in a distorted octahedral coordination environment. In the crystal, N—H...O and O—H...O hydrogen bonds connect chains and solvent water molecules, forming a two-dimensional network parallel to (101).

Self-assembly of [2+2] Co(II) metallomacrocycles and Ni(II) metallogels with novel bis(pyridylimine) ligands

Two novel 46-membered Co(II) metallomacrocycles, [Co2Cl4(L1)2]·CH2Cl2 and [Co2(NO3)2(L1)2(H2O)2⊂(NO3)](NO3)·4H2O, with 1,4-bis[4-(2-pyridylmethylideneamino)phenyloxy]benzene (L1) have been synthesized and characterized. Both Co(II) centers in these dinuclear complexes possess an octahedral coordination environment formed by a N4 donor set of two L1 ligands and two chloride or one monodentate nitrate and one water molecule, respectively. Whereas in the first case disordered solvent molecules are present in the macrocycle's cavity in the second one a nitrate anion is embedded. Furthermore, the molecular structures of L1, L3 and L4 were determined and solution studies of the complex formation of these ligands with Co(II), Ni(II) and Cu(II) in dichloromethane/methanol (v/v = 1:1) using UV/Vis and ESI-MS spectroscopic measurements were performed. In contrast to the self-assembling behavior of the bis(2-pyridylimine) ligand L1 the bis(3-pyridylimine) ligand L4 was also demonstrated to form metallogels when reacted with NiCl2·6H2O in tetrahydrofuran under defined conditions.

Crystal structure of tris-(trans-1,2-cyclo-hexa-ne-diamine-κ(2) N,N')chromium(III) tetra-chlorido-zincate chloride trihydrate from synchrotron data.

The structure of the title double salt, [Cr(rac-chxn)3][ZnCl4]Cl·3H2O (chxn is trans-1,2-cyclo-hexa-nedi-amine; C6H14N2), has been determined from synchrotron data. The Cr(III) ion is coordinated by six N atoms of three chelating chxn ligands, displaying a slightly distorted octa-hedral coordination environment. The distorted tetra-hedral [ZnCl4](2-) anion, the isolated Cl(-) anion and three lattice water mol-ecules remain outside the coordination sphere. The Cr-N(chxn) bond lengths are in a narrow range between 2.0737 (12) and 2.0928 (12) Å; the mean N-Cr-N bite angle is 82.1 (4)°. The crystal packing is stabilized by hydrogen-bonding inter-actions between the amino groups of the chxn ligands and the water mol-ecules as donor groups, and O atoms of the water mol-ecules, chloride anions and Cl atoms of the [ZnCl4](2-) anions as acceptor groups, leading to the formation of a three-dimensional network. The [ZnCl4](2-) anion is disordered over two sets of sites with an occupancy ratio of 0.94:0.06.

Synthesis and X-ray crystal structure of novel cobalt(II) complexes having oligopyridine ligands

The quinquepyridine analogue L1, diquinolylterpyridine analogue L3 and a new oligopyridine, quinolylquaterpyridine L2, have been prepared by an iridium-catalyzed synthetic method. The quinquepyridine L1 has five pyridine rings which are connected to each other at the 2- and 6-positions of each pyridine ring. One of the two terminal pyridine rings of L1 was replaced by a quinoline ring to give L2, while both terminal pyridine rings were replaced by two quinoline rings to give L3. All of these oligopyridines produce the corresponding new cobalt(II) complexes. The reaction of cobalt(II) chloride with L1 gave the dinuclear cobalt(II) complex [CoClL1]2(CoCl4) (4a), having an interesting double-stranded helical structure, differing from the double helical dinuclear cobalt complexes previously reported by other groups. The structure of 4a was determined by single-crystal X-ray crystallography. In 4a, the two cobalt centers are equivalent, while the other dinuclear cobalt complexes had non-equivalent cobalt centers. Each cobalt center in 4a displays a distorted octahedral coordination environment, and L1 coordinates to each cobalt with “terpyridyl” and “bipyridyl” fragments. The reaction of L2 with cobalt(II) nitrate gave the dinuclear cobalt(II) complex [Co2L2(NO3)4] (5). Complex 5 has one ligand molecule, while the complex 4a has two ligand molecules. In 5, the terpyridyl fragment of L2 is coordinated to one cobalt center and the quinolylpyridyl fragment is coordinated to the other cobalt center. The two cobalt centers are bridged by one oxygen atom of a nitrate group. The reaction of L3 with cobalt(II) nitrate gave a similar dinuclear cobalt complex, [Co2L3(NO3)4] (6). In 6, the quinolylbipyridyl and quinolylpyridyl fragments each coordinate to a different cobalt center. The bridging nitrate group in 6 is coordinated to the two cobalt centers through two oxygen atoms.

La2SrCr2O7F2: A Ruddlesden-Popper Oxyfluoride Containing Octahedrally Coordinated Cr(4+) Centers.

The low-temperature fluorination of the n = 2 Ruddlesden-Popper phase La2SrCr2O7 yields La2SrCr2O7F2 via a topochemical fluorine insertion reaction. The structure-conserving nature of the fluorination reaction means that the chromium centers of the initial oxide phase retain an octahedral coordination environment in the fluorinated product, resulting in a material containing an extended array of apex-linked Cr(4+)O6 units. Typically materials containing networks of octahedrally coordinated Cr(4+) centers can only be prepared at high pressure; thus, the preparation of La2SrCr2O7F2 demonstrates that low-temperature topochemical reactions offer an alternative synthesis route to materials of this type. Neutron diffraction, magnetization, and μ(+)SR data indicate that La2SrCr2O7F2 undergoes a transition to an antiferromagnetic state below TN ≈ 140 K. The structure-property relations of this phase and other Cr(4+) oxide phases are discussed.

Crystal structure of trans-diammine(1,4,8,11-tetra-aza-cyclo-tetra-decane-κ(4) N)chromium(III) tetra-chlorido-zincate chloride monohydrate from synchrotron data.

The asymmetric unit of the title complex salt, [Cr(C10H24N4)(NH3)2][ZnCl4]Cl·H2O, is comprised of four halves of the Cr(III) complex cations (the counterparts being generated by application of inversion symmetry), two tetra-chlorido-zincate anions, two chloride anions and two water mol-ecules. Each Cr(III) ion is coordinated by the four N atoms of the cyclam (1,4,8,11-tetra-aza-cyclo-tetra-deca-ne) ligand in the equatorial plane and by two N atoms of ammine ligands in axial positions, displaying an overall distorted octa-hedral coordination environment. The Cr-N(cyclam) bond lengths range from 2.0501 (15) to 2.0615 (15) Å, while the Cr-(NH3) bond lengths range from 2.0976 (13) to 2.1062 (13) Å. The macrocyclic cyclam moieties adopt the trans-III conformation with six- and five-membered chelate rings in chair and gauche conformations. The [ZnCl4](2-) anions have a slightly distorted tetra-hedral shape. In the crystal, the Cl(-) anions link the complex cations, as well as the solvent water mol-ecules, through N-H⋯Cl and O-H⋯Cl hydrogen-bonding inter-actions. The supra-molecular set-up also includes N-H⋯Cl, C-H⋯Cl, N-H⋯O and O-H⋯Cl hydrogen bonding between N-H or C-H groups of cyclam, ammine N-H and water O-H donor groups, and O atoms of the water mol-ecules, Cl(-) anions or Cl atoms of the [ZnCl4](2-) anions as acceptors, leading to a three-dimensional network structure.

Crystal structure of trans-di-chlorido-(1,4,8,11-tetra-aza-undecane-κ(4) N)chromium(III) perchlorate determined from synchrotron data.

The structure of the title complex, [CrCl2(2,3,2-tet)]ClO4 (2,3,2-tet is 1,4,8,11-tetra-aza-undecane, C7H20N4), has been determined from synchrotron data. The Cr(III) ion is coordinated by the four N atoms of the 1,4,8,11-tetra-aza-undecane ligand in the equatorial plane and two chloride ions in an axial arrangement, displaying a slightly distorted octa-hedral coordination environment. The two H atoms of the secondary amines are grouped on the same side of the equatorial N4 plane (meso-RS conformation). The Cr-N bond lengths range from 2.069 (2) to 2.084 (2) Å, while the mean Cr-Cl bond length is 2.325 (2) Å. The crystal structure is stabilized by inter-molecular hydrogen-bonding inter-actions between the primary and secondary amine groups of the 2,3,2-tet ligands, the Cl ligands and the O atoms of the perchlorate counter-anion, forming corrugated layers parallel to (010).

Crystal structure of di-aqua-tris-(1-ethyl-1H-imidazole-κN (3))(sulfato-κO)nickel(II).

In the title complex, [Ni(SO4)(C5H8N2)3(H2O)2], the Ni(II) ion is coordinated by three facial 1-ethyl-1H-imidazole ligands, one monodentate sulfate ligand and two water mol-ecules in a slightly distorted octa-hedral coordination environment. In the crystal, two pairs of O-H⋯O hydrogen bonds link complex mol-ecules, forming inversion dimers incorporating R 2 (4)(8), R 2 (2)(8) and R 2 (2)(12) rings. The dimeric unit also contains two symmetry-unique intra-molecular O-H⋯O hydrogen bonds. In addition, weak C-H⋯O hydrogen bonds, weak C-H⋯π inter-actions and π-π inter-actions with a centroid-centroid distance of 3.560 (2) Å combine to form a three-dimensional network. One of the ethyl groups is disordered over two sets of sites with occupancies in the ratio 0.586 (7):0.414 (7).

Di-μ-chlorido-bis[(2,2′-bipyridine-κ2N,N′)chlorido(N,N-dimethylformamide-κO)nickel(II)

The title compound, [Ni2Cl2(μ-Cl)2(C10H8N2)2(C3H7NO)2], exists as a centrosymmetric dimer of two octahedral nickel centers. In the crystal, two chloride ions bridge the two nickel centers with one terminal chloride ion bound to each nickel atom. Coupled with a chelating bipyridine ligand and an O-boundN,N-dimethylformamide solvent molecule, each nickel center exhibits an slightly distorted octahedral coordination environment. The meridional chloride ions all sit in equatorial positions, with the bipyridine ligand occupying one equatorial and one axial position, and theN,N-dimethylformamide ligand occupying the final axial position. The 2,2′-bipyridine ligand binds to nickel in a near planar fashion, with the non-H atoms possessing a mean devation from planarity of 0.046 Å. No π–π interactions are observed in the crystal.

Crystal structure of bis-(1,3-di-amino-propane-κ(2) N,N')bis-[2-(4-nitro-phen-yl)acetato-κO]cadmium.

In the structure of the title compound, [Cd(C8H6NO4)2(C3H10N2)2], the Cd(II) atom is located on a center of symmetry with one independent Cd-O distance of 2.3547 (17) Å and two Cd-N distances of 2.3265 (18) and 2.3449 (19) Å. The Cd(II) atom has an overall octa-hedral coordination environment. Several types of hydrogen-bonding inter-actions are evident. Both intra- and inter-molecular inter-actions occur between the amino groups and the O atoms of the acetate group. These N-H⋯O hydrogen bonds lead to a layered structure extending parallel to the bc plane. In addition, weak inter-molecular C-H⋯O inter-actions involving the nitro groups exist, leading to the formation of a three-dimensional network structure.