Occurrence Of Depressive Symptoms Research Articles

Relationship between the number of lost teeth and the occurrence of depressive symptoms in middle-aged adults: a cross-sectional study

BackgroundMany recent studies suggest the existence of a relationship between oral health and the occurrence of depressive symptoms. The aim of this study was to assess the relationship between the number of lost teeth and the occurrence of depressive symptoms in middle-aged adults.MethodsAn analysis was performed on the data obtained from the PONS project (POlish-Norwegian Study), conducted in the Świętokrzyskie Province in Poland in 2010–2011. The research material included the cross-sectional data of 11,901 individuals aged 40–64 years (7967 women). Depressive symptoms, used as outcome variables, were assessed with a questionnaire. The participants provided the responses to questions concerning the occurrence of eight symptoms over the last 12 months. The answers were scored as 1 point or 0 points. The participants were divided into three tercile groups based on their total scores: no or mild (0–2 points), moderate (3–5 points), and severe depressive symptoms (6–8 points). The self-reported number of lost teeth was analysed according to the following categories: 0–4, 5–8, 9–27, and a complete lack of natural teeth. Multivariable logistic regression analysis for depressive symptoms was used in relation to the number of lost teeth. The following covariates were included in the adjusted model: age, sex, place of residence, education, marital status, BMI, diabetes status, stressful life events in the last year, use of antidepressants, smoking, and sugar and sweet consumption.ResultsThe likelihood of both moderate (OR = 1.189; 95%CI: 1.028–1.376; p < .020) and severe (OR = 1.846; 95%CI: 1.488–2.290; p < .001) depressive symptoms showed the strongest relationship with a total lack of natural teeth. A loss of more than 8 natural teeth was also significantly associated (OR = 1.315; 95%CI: 1.075–1.609; p < .008) with the occurrence of severe depressive symptoms.ConclusionsThe loss of natural teeth was positively related to the occurrence of depressive symptoms in middle-aged adults. Thus, there is an urgent need to intensify stomatological prophylaxis, education and treatment for middle-aged individuals.

Proximity to public green spaces and depressive symptoms among South African residents: a population-based study

BackgroundExposure to green spaces has been suggested to improve mental health and may reduce the risk of depression. However, there is generally limited evidence on the association between green spaces and depression originating from low-and middle-income countries and Africa in particular. Here, we investigate the association between proximity to public green spaces and depressive symptoms among residents of Gauteng Province, South Africa.MethodsWe used data from the 2017/2018 Gauteng quality of life survey. We included all individuals aged 18 years or older residing in the nine municipalities of Gauteng Province that completed the survey (n = 24,341). Depressive symptoms were assessed using the Patient Health Questionnaire-2. Proximity to public green spaces was defined as self-reported walking time (either less or greater than 15 min) from individuals’ homes to the nearest public green space. To assess the association between access to public green spaces and depressive symptoms, we used mixed-effects models, adjusted for age, sex, population group (African, Indian/Asian, Coloured (mixed race), and White), educational attainment, and municipality. We additionally performed stratified analyses by age, sex, educational attainment, and population group to evaluate whether associations differed within subgroups. Associations are expressed as prevalence ratios (PR) and their 95% confidence intervals (95% CI).ResultsWe observed a 6% (PR = 0.94, 95%CI = 0.92–0.96) prevalence reduction in depressive symptoms for individuals who reported that the nearest public green space was less than 15 min from their homes as compared to those who reported > 15 min. After stratification, this inverse association was stronger among females, individuals aged 35–59 years,those with higher levels of educational attainment, and Coloured individuals as compared to their counterparts.ConclusionOur findings suggest that public green spaces close to residential homes may be associated with a reduction in the occurrence of depressive symptoms among urban populations in resource-constrained settings like South Africa.

Adherence to Mediterranean diet is inversely associated with depressive symptoms in older women: findings from the NutBrain Study.

Data on the association of the Mediterranean diet (MD) with depressive symptoms in older people at high risk of depression are scarce. This study aimed to investigate the cross-sectional association of the adherence to the MD and its components with depressive symptoms in an Italian cohort of older men and women. A total of 325 men and 473 women aged 65–97 years (2019–2023) answered a 102-item semi-quantitative FFQ, which was used to calculate the Mediterranean diet score (MDS). Depressive symptoms were assessed using the Centre for Epidemiological Studies Depression Scale; subjects with a score of 16 or more were considered to have depression. Multivariable logistic regression was used for statistical analysis. The occurrence of depressive symptoms was 19·8 % (8·0 % men, 27·9 % women). High adherence to MDS (highest tertile) significantly reduced the odds of having depressive symptoms by 54·6 % (OR 0·454, 95 % CI 0·266, 0·776). In sex-stratified analysis, the reduction was evident in women (OR 0·385, 95 % CI 0·206, 0·719) but not in men (OR 0·828, 95 % CI 0·254, 2·705). Looking at the association of MDS components with depressive symptoms, we found an inverse significant association with fish consumption and the MUFA:SFA ratio above the median only in women (OR 0·444, 95 % CI 0·283, 0·697 and OR 0·579, 95 % CI 0·345, 0·971, respectively). High adherence to the MDS, and a high fish intake and MUFA:SFA ratio were associated with lower depressive symptoms in women only. Future longitudinal studies are needed to confirm these findings and to explore the underlying biological mechanisms.

Depression: A Contributing Factor to the Clinical Course in Myasthenia Gravis Patients.

Background and Objectives: The association between myasthenia gravis (MG) and depression is intricate and characterized by bidirectional causality. In this regard, MG can be a contributing factor to depression and, conversely, depression may worsen the symptoms of MG. This study aimed to identify any differences in the progression of the disease among patients with MG who were also diagnosed with depression as compared to those without depression. Our hypothesis focused on the theory that patients with more severe MG symptoms may have a higher likelihood of suffering depression at the same time. Materials and Methods: One hundred twenty-two male and female patients (N = 122) aged over 18 with a confirmed diagnosis of autoimmune MG who were admitted to the Neurology II department of Myasthenia Gravis, Clinical Institute Fundeni in Bucharest between January 2019 and December 2020, were included in the study. Patients were assessed at baseline and after six months. The psychiatric assessment of the patients included the Hamilton Depression Rating Scale-17 items (HAM-D), and neurological status was determined with two outcome measures: Quantitative Myasthenia Gravis (QMG) and Myasthenia Gravis Activities of Daily Life (MG-ADL). The patients were divided into two distinct groups as follows: group MG w/dep, which comprised 49 MG patients diagnosed with depressive disorder who were also currently receiving antidepressant medication, and group MG w/o dep, which consisted of 73 patients who did not have depression. Results: In our study, 40.16% of the myasthenia gravis (MG) patients exhibited a comorbid diagnosis of depression. Among the MG patients receiving antidepressant treatment, baseline assessments revealed a mean MG-ADL score of 7.73 (SD = 5.05), an average QMG score of 18.40 (SD = 8.61), and a mean Ham-D score of 21.53 (SD = 7.49). After a six-month period, a statistically significant decrease was observed in the MG-ADL (2.92, SD = 1.82), QMG (7.15, SD = 4.46), and Ham-D scores (11.16, SD = 7.49) (p < 0.0001). These results suggest a significant correlation between MG severity and elevated HAM-D depression scores. Regarding the MG treatment in the group with depression, at baseline, the mean dose of oral corticosteroids was 45.10 mg (SD = 16.60). Regarding the treatment with pyridostigmine, patients with depression and undergoing antidepressant treatment remained with an increased need for pyridostigmine, 144.49 mg (SD = 51.84), compared to those in the group without depression, 107.67 mg (SD = 55.64, p < 0.001). Conclusions: Our investigation confirms that the occurrence of depressive symptoms is significantly widespread among individuals diagnosed with MG. Disease severity, along with younger age and higher doses of cortisone, is a significant factor associated with depression in patients with MG. Substantial reductions in MG-ADL and QMG scores were observed within each group after six months, highlighting the effectiveness of MG management. The findings suggest that addressing depressive symptoms in MG patients, in addition to standard MG management, can lead to improved clinical outcomes.

Association between ethylene oxide levels and depressive symptoms: A cross-sectional study based on NHANES 2013–2018 database

Background and AimEthylene oxide (EO) is a commonly used compound with known health risks. However, the specific association between EO exposure and the development of depressive symptoms has not been well established. Therefore, this study aimed to examine the potential association between EO exposure, as indicated by hemoglobin adduct of ethylene oxide (HbEO) levels, and the occurrence of depressive symptoms. MethodsWe employed logistic regression, restricted cubic spline, and subgroup analysis to investigate the association between EO exposure and the occurrence of depressive symptoms. Additionally, we conducted a mediating effect analysis to explore the potential factors influencing the association between EO exposure and depressive symptoms. ResultsElevated HbEO levels were associated with the development of depressive symptoms. After adjusting for potential confounders, the highest quartile of HbEO levels showed an odds ratio (OR) of 3.37 [95 % confidence interval (CI): 1.87–6.10, P = 0.002] compared with the lowest quartile. Additionally, a linear association was observed between HbEO levels and the risk of depressive symptoms. We also revealed that the levels of several inflammatory factors and triglycerides mediated the association between EO exposure and the occurrence of depressive symptoms. ConclusionsHigher levels of EO exposure were related to an increased risk of developing depressive symptoms. The analysis also suggested that the inflammatory response might play a mediating role in the pathway from EO exposure to depressive symptoms.

The Relationship of Rejection Sensitivity to Depressive Symptoms in Adolescence: The Indirect Effect of Perceived Social Acceptance by Peers.

Rejection sensitivity (RS), the tendency to expect, perceive and overreact to rejection from others, has been linked to children's and adolescents' increased vulnerability to depressive symptoms, negatively affecting their perceptions of the quality of their relationship with their peers. The aim of this study is to examine (a) the indirect effect of perceived peer social acceptance in the relationship between RS and depressive symptoms in a sample of Greek adolescents, (b) the differential effect of the different components of rejection sensitivity (angry and anxious RS) on the model, and (c) possible gender differences. The sample of the study consists of 295 adolescents (139 boys, 156 girls, Mage = 14.20, SD = 1.60) residing in the greater Heraklion Prefecture area. Data collection was carried out using self-report questionnaires that measured demographic characteristics, self-perceptions about their peer relationships (self-perception profile for adolescents/SPPA), susceptibility to rejection (children's rejection sensitivity questionnaire/CRSQ), and depressive symptoms (children's depression inventory/CDI). Results showed that (a) RS was positively related to depressive symptoms and negatively related to adolescents' perceptions of their relationships, (b) relationship perceptions were negatively related to depressive symptoms, and gender differences were also found, (c) perceived social acceptance by peers was found to have an indirect effect in the relationship between RS and depressive symptoms, with girls showing a greater effect, and (d) differences were observed in the mediating model between the components of RS, with the mediating effect of perceptions being higher in the model with anxious RS, which appears to confirm previous theoretical postulations. The results of this study highlight the importance of adolescents' perceptions of their peer relationships in the occurrence of depressive symptoms during this developmental period, especially in youths with anxious rejection sensitivity.

Decomposition analysis of the difference in depressive symptoms between urban and rural employed people in China: Unpaid work plays an important role.

Focusing on the relationship between unpaid labor and the occurrence of depressive symptoms, this study aimed to explore the factors influencing the inequality of depressive symptoms and their contribution among Chinese urban and rural employed people. This study utilized the 2020 China Family Panel Studies' national resampling data. Multivariate logistic regression was used to explore the factors influencing the occurrence of depressive symptoms among employed persons in urban and rural areas in China, respectively. Fairlie decomposition was used to explore the contribution of influencing factors such as unpaid labor to the difference in the occurrence of depressive symptoms between urban and rural areas. About 2,136 (21.70%) participants had depressive symptoms, of which 1,197 (24.75%) rural employed people had depressive symptoms and 939 (18.75%) urban employed people had depressive symptoms. The results of Fairlie decomposition analysis showed that 70.51% of the differences in depressive symptoms between urban and rural Chinese employed people could be explained by the covariates included in this study, including education level (52.44%), age (-11.91%), housework time (10.42%), self-rated health status (10.22%), self-rated income status (2.53%), exercise (2.36%), job satisfaction status (1.99%), chronic disease status (1.90%), and marital status (1.79%). This study found that the proportion of depressive symptoms was lower among urban employed residents than among rural employed residents. This difference was mainly caused by unpaid labor time, socioeconomic status, personal lifestyle, and health status. Housework, which is one of the unpaid labor, contributed to this depressive symptom difference in the third place.

Folic acid supplementation during pregnancy and postpartum depressive symptoms.

To verify whether folic acid supplementation during pregnancy is associated with the occurrence of maternal depressive symptoms at three months postpartum, in the 2015 Pelotas Birth Cohort. This study included 4,046 women, who were classified into three groups: did not use folic acid supplementation during pregnancy; used during only one trimester of pregnancy; and used for two or three trimesters. Depressive symptoms were assessed at three months postpartum using the Edinburgh Postnatal Depression Scale (EPDS), at cutoff points ≥ 10 (mild symptoms) and ≥ 13 (moderate to severe intensity). The overall prevalence of mild symptoms was of 20.2% (95%CI 19.0-21.5), and moderate and severe was 11% (95%CI 10.0-12.0). The prevalence of EPDS ≥ 10 was of 26.8% (95%CI 24.0-29.5) among women who did not use folic acid and 18.1% for both those who used it during one trimester of pregnancy (95%CI 16.1-20.1) and those who used it for two or three trimesters (95%CI 16.0-20.2). The prevalence of EPDS ≥ 13 was of 15.7% (95%CI 13.5-17.9) in those who did not use folic acid, 9.1% (95%CI 7.5-10.6) in those who used it for one trimester, and 9.4% (95%CI 7.8-11.0) in those who used it for two or three trimesters. In the adjusted analyses, there was no statistically significant association between the use of folic acid during pregnancy and the occurrence of depressive symptoms at three months postpartum. There was no association between folic acid supplementation during pregnancy and postpartum depression at three months.

Addictive Social Media Use and Depressive Symptoms in Adolescents

Abstract: Theoretical Background: The use of social media has become an integral part of the lives of young people. Negative effects on mental health have been reported previously; however, it remained unclear whether the amount of time spent with social media use per se or its usage patterns lead to possible impairments. Addictive use is characterized by compulsive usage patterns in contrast to a flexible use. Objective: The present work investigated the associations between the amount of time spent with social media, the usage pattern (i. e., addictive use vs. flexible use), and the occurrence of depressive symptoms. Method: Cross-sectional data based on the self-reports of 513 high-school students aged 11 – 19 ( M = 12.91, SD = 1.02) from 39 classes (18 schools) in Baden-Wuerttemberg, Germany, are presented. Hierarchically linear models accounted for the nested structure and were applied to investigate the predictive significance of time spent with social media and addictive use of social media on depressive symptoms. Results: Addictive use of social media could be identified as a significant predictor of depressive symptoms and explained 17 % of variance in depressive symptoms in the present model. Time spent with social media use did not explain a significant share of variance in depressive symptoms, after controlling for addictive social media use. Discussion and Conclusion: These findings highlight that it is not the time spent on social media per se, but the addictive usage patterns that explain a significant share of depressive symptoms in adolescents. Although a reciprocal or circular association between both disorders can be assumed, addictive usage patterns of social media may represent a potential risk to adolescents’ mental health. To prevent negative consequences of social media use, interventions should focus on the particular functionality of social media use.

Maternal expectations and paternal self-efficacy as factors associated with the occurrence of depressive symptoms in parents after childbirth.

Depressive symptoms with onset after the birth of a child can affect both parents. The aim of the presented study was to determine whether fathers and mothers differ in terms of postpartum depression symptoms and such variables as the sense of parental competence and the prenatal expectations of discrepancy, and whether these variables are related to the occurrence of postpartum depression symptoms in women and men. 271 people, including 165 women and 106 men, who became parents in the last 12 months, were examined. The Edinburgh Postnatal Depression Scale (EPDS), Parental Sense of Competence Scale (PSOC) and Prenatal Expectations Scale (PES) was used. The results indicate differences between mothers and fathers in postpartum depressive symptoms, parental competencies, and prenatal expectations discrepancy as well. While maternal depression symptoms are determined by failure to meet prenatal expectations, depressive symptoms in new fathers are associated with a low sense of paternal competence.

The Relationship between Diet and the Occurrence of Depressive Symptoms in a Community Example with High Rates of Social Deprivation: A Cross-Sectional Study.

Research suggests that various biological and psychosocial mechanisms are involved in the heterogeneous and complex relationship between dietary patterns and depressive symptoms. The occurrence of depressive symptoms is thought to be related to socioeconomic status (SES), with those with lower SES being more likely to experience persistent depression. The aim of the undertaken study was to investigate whether socioeconomic and health variables are associated with dietary assessment in a population with high rates of social deprivation and whether a relationship exists between dietary assessment and depressive symptoms (DS). The respondents' nutrition was evaluated through a qualitative method, using the Perinumeric Periodic Table questionnaire by Starzyńska. At the same time, the prevalence of DS was assessed employing the Patient Health Questionnaire-9 (PHQ-9). In the DS screening (PHQ-9 ≥ 10), in the entire study population, the risk of DS was 16.1% (n = 605). In our entire study population, up to 61.2% (n = 2297) of the respondents exhibited poor dietary patterns. In the multivariate model, women with almost adequate or poor dietary assessment were 1.62 and 2.18 times more likely to score at least 10 on the PHQ-9 questionnaire, as compared to women whose dietary assessment was good or adequate. In conclusion, it was determined that sociodemographic variables affect nutritional habits. Women who lived in rural areas limited to a vocational education had significantly poorer diets. Moreover, men, younger men, smokers, and those without chronic diseases were characterized by a poorer dietary assessment. Additionally, women who had a better dietary assessment were significantly more likely to have lower scores on the questionnaire assessing the occurrence of DS (PHQ-9 10).

Unpacking the Specific Associations Between Adverse Childhood Experiences and Depressive Symptoms among the Middle-Aged and Elderly Chinese Populations: A Dimensional Approach and Latent Class Analysis in a Cohort Study

Background. Adverse childhood experiences (ACEs) are recognized as key risk factors linked to poor mental health throughout life. However, research on the specific associations between ACE dimensions and depressive symptoms (DSs) among the Chinese population during mid to late life is rare. Objectives. This study aims to investigate the specific effects of different dimensions of ACEs on the new occurrence of DSs and the number of times with DSs among the middle-aged and elderly Chinese populations. Methods. The analysis included 3979 adults aged ≥45 years with four repeated measurements of the 10-item Center for Epidemiological Studies Depression Scale from the China Health and Retirement Longitudinal Study 2011–2018. Three types of ACE dimensions (total, deprivation, and threat-related ACEs) were conceptualized in accordance with the 15 types of ACEs that occurred before the age of 18 years recorded using the Life History Survey Questionnaire in 2014. In addition, latent class analysis (LCA) was utilized as an additional method for identifying distinct ACE clusters. The Cox regression and ordered logistic regression were used to estimate the risk of ACEs on DSs. Results. Among the 3979 participants, 1656 developed a new occurrence of DSs during follow-up, with 998, 438, and 220 exhibiting DSs one, two, and three times. For total and deprivation-related ACEs, only the group with ≥3 ACEs was significant with the new occurrence of DSs when compared with the no ACE group, and the adjusted hazard ratios (HRs) (95% confidence interval) were 1.562 (1.296, 1.882) and 1.446 (1.221, 1.712), respectively. With regard to threat-related ACEs, all three groups (1 ACE, 2 ACEs, and ≥3 ACEs) were significantly associated with the new occurrence of DSs. The HRs were 1.260 (1.115, 1.425), 1.407 (1.212, 1.634), and 1.585 (1.366, 1.840), respectively. The findings of total, deprivation-related, and threat-related ACEs and their associations with the number of times with DSs represent a similar phenomenon. The LCA revealed five ACE clusters. Compared to the “low risk” cluster, the “poor parent relationship” cluster and the “physical abuse” cluster were linked to an increased risk of the new occurrence of DSs and the number of times with DSs. The results of the subgroup analysis by sex and age were consistent with the total population. Conclusions. Individuals who have experienced higher ACE scores in early life face a higher risk of developing a new occurrence of DSs and multiple detected DSs in mid to late life, particularly in the case of threat-related ACEs. Parsing ACEs is imperative to explore their distinct effects on DSs and the underlying mechanisms. In addition, Incorporating ACE screening into regular health checks among the middle-aged and elderly populations is recommended. Moreover, targeted mental health interventions should be delivered to those who have experienced early life adversities, particularly threat-related ACEs, to promote healthy aging.

A-50 A Review of the Dangers of Misdiagnosing Concussions as Depression

Abstract Purpose Underrepresentation of concussion diagnoses is of increasing concern for the health and wellbeing of young athletes. Similarly, there is increased attention on the mental health of student athletes. Less addressed, however, is potential for misdiagnosis between these concerns. This literature review explains the underpinnings of the potential misinterpretation of concussion symptoms under the guise of depression. Methods Peer reviewed studies published within the last 25 years were included in this review. Specific statistics referring to current high school and collegiate athletes included peer reviewed articles from 2020-2023. Results Depression and concussions are correlated, further, experiencing TBI and concussion puts an individual at increased risk for developing depression. Additionally, many symptoms of concussion overlap with diagnostic criteria for depression such as: fatigue, suicidal ideation, anhedonia, sleep difficulties, and low mood. The risk of misdiagnosis of depression in concussed athletes is apparent. However, no known study has demonstrated the rate of this misdiagnosis. Treatment for concussion recovery and depression management is fundamentally different, which calls for accurate differentiation between the occurrence of depressive symptoms and head trauma induced symptoms. Conclusions Future research regarding affordable and accessible methods to differentiate depression from concussion will help reduce the chances of misdiagnosis. Understanding the considerable overlap in symptomatology and importance of recognizing both concussion when it occurs as well as depression is essential for individuals working with student athletes. Improved education for high school and college coaches and athletes, along with clinicians and physicians is a key component in this change.

Childhood abuse and association with adult depressive symptoms among people with cardiovascular disease.

To study the association between the total/different types of childhood abuse and adult depressive symptoms in people with cardiovascular disease (CVD). The subjects were people with CVD who continuously participated in the China Health and Retirement Longitudinal Study (CHARLS) life history survey and the 2018 wave of the CHARLS national baseline Survey. Multi-level logistic regression models were used to analyze the relationship between emotional neglect, physical neglect, physical abuse and adult depressive symptoms. A total of 4,823 respondents were included in this study. The incidence of childhood abuse (existed emotional neglect, physical neglect or physical abuse) was 43.58% among people over 45 years old with CVD, which was higher than that of the general population (36.62%, p < 0.05). Adjusted model showed that overall childhood abuse was associated with adult depressive symptoms (OR = 1.230, 95%CI:1.094-1.383). Among different types of childhood abuse, only physical abuse was associated with depressive symptoms in adulthood (OR = 1.345, 95%CI:1.184-1.528). Compared with that of the general population, the incidence of childhood abuse in CVD population is higher. Physical abuse in childhood increased the risk of depressive symptoms in adulthood. It suggested that the occurrence of depressive symptoms was the result of related factors in the whole life course. In order to prevent the depressive symptoms, childhood abuse also needs to be considered. It is very important to identify and prevent the continuation of childhood abuse in time.

RETN gene polymorphisms interact with alcohol dependence in association with depression.

Previous studies suggest that alcohol dependence is associated with increased risk of depression. The occurrence of depressive symptoms is related to polymorphisms in various genetic regions. This study aimed to investigate the interaction of RETN gene polymorphisms (rs1477341, rs3745368) with alcohol dependence on depressive symptoms in adult male during acute alcohol withdrawal. A total of 429 male adults were recruited in this study. Alcohol dependence was assessed using the Michigan alcoholism screening test (MAST). Depression was assessed using the 20-item self-rating depression scale (SDS). Hierarchical regression analysis was used to evaluate the interaction between genes and alcohol dependence on depression. Region of significance (ROS) test was used to explain the interaction effect. The strong and weak forms of the differential susceptibility and diathesis models were used to determine which fits the data better. Our results showed that MAST scores were significantly positively associated with SDS scores (r = 0.23, p < 0.01) in alcohol-dependent patients during alcohol withdrawal. The interaction between genotype and alcohol dependence was significant (β = -0.14, p < 0.05) in a strong diathesis-stress model. Susceptibility for depression symptoms was associated with alcohol dependence in RETN rs1477341 A carriers. Specifically, those that showed more alcohol dependence and the A allele of RETN rs1477341 exhibited more depression symptoms. However, RETN rs3745368 had no significant interaction with alcohol dependence. The A allele of RETN rs1477341 may correlate with susceptibility to depression symptoms in alcohol-dependent individuals during acute alcohol withdrawal.

Vliv socioekonomického statusu na výskyt depresivních symptomů v populaci Česka – výsledky EHIS 2019

This paper examines the effect of socioeconomic factors (including achieved level of educational attainment, economic activity, and income) on the occurrence of depressive symptoms in the Czech population. The analyses are based on the cross-sectional European Health Interview Survey (EHIS) from 2019. The results of these analyses show the individual and also combined effect of education, economic activity, and income. The odds ratio of depressive symptoms is the highest among respondents with primary education, those who are unemployed, and those with lower income. Socioeconomic status is significantly associated with depressive symptoms.

Changes in Satisfaction with Meaningful Activities and Onset of Depressive Symptoms among Community-Dwelling Japanese Older Adults: A Population-Based Study Before and During the COVID-19 Pandemic.

This study aimed to clarify the association between changes in satisfaction with meaningful activities and the occurrence of depressive symptoms before and during the coronavirus disease 2019 (COVID-19) pandemic. A population-based prospective cohort study (Tarumizu Study). A total of 231 community-dwelling older adults aged ≥65years without depressive symptoms at baseline. The participants completed baseline (June to December 2018, before the COVID-19 pandemic) and follow-up (September to December 2021, during the COVID-19 pandemic) assessments. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale (GDS-15) and defined by a GDS-15 score of ≥5. Participants selected meaningful activities from the 95 activities included in the Aid for Decision-Making in Occupation Choice, and their satisfaction levels were evaluated. Satisfaction with the most meaningful activities was assessed as to whether it was maintained/improved or decreased at follow-up. In the follow-up survey, 31 (14.3%) participants reported the occurrence of depressive symptoms. Compared with before the COVID-19 pandemic, the rates of meaningful activities during the COVID-19 pandemic decreased for interpersonal interaction and social life and increased for leisure, sports, self-care, and domestic life. Logistic regression analysis revealed that changes in satisfaction with meaningful activity were associated with the occurrence of depressive symptoms after adjusting for demographic variables, baseline GDS scores, cognitive and physical status, and instrumental activities of daily living (odds ratio, 2.78; 95% confidence interval, 1.17-6.59, P= .020). To avoid decreasing satisfaction with meaningful activities, supporting older adults may be protective against the occurrence of depressive symptoms. Our findings highlight the need for health care professionals to not only encourage older adults to participate in activities for their mental health but also consider whether the activities are meaningful or satisfying for them.

The risk factors of progestational anxiety, depression, and sleep disturbance in women with recurrent pregnancy loss: A cross-sectional study in China.

The risk factors of progestational anxiety, depression, and sleep disturbance in women with a history of recurrent pregnancy loss (RPL) remain controversial, additional study is needed to investigate the incidence and risk factors of progestational anxiety, depression, and sleep quality in RPL women. A cross-sectional study was conducted among 663 non-pregnant RPL women in Northeast China from October 2019 to July 2022. We assessed the state of anxiety, depression, and sleep quality before pregnancy using structured questionnaires, including sociodemographic characteristics, state-trait anxiety scale (STAI), center for epidemiological survey, depression scale (CES-D), Pittsburgh sleep quality index (PSQI), and symptom self-rating scale (SCL-90). Logistic regression was used to evaluate the association between sleep quality and anxiety, depression. Pearson's correlation was used to evaluate the correlation between anxiety and depression. Multivariate logistic regression analysis was used to find the risk factors of depression symptoms. The receiver operating characteristic curve (ROC) was used to evaluate the predictive value of the model. The incidence of state anxiety, trait anxiety, depression, and sleep disturbance in RPL women were 60.3, 51.7, 33.9, and 31.2%, respectively. The level of anxiety and depression in RPL women varied at different stages of treatment. In a longitudinal study (25 pairs), we found the level of state anxiety and trait anxiety were significantly lower after the cause was identified. Sleep disturbance is positively correlated with anxiety and depression. Logistic regression showed that the number of miscarriages ≥4 (Odds ratio (OR) = 2.268, 95%CI 1.300-3.956), Low household family income (OR = 1.613, 95%CI 1.036-2.513/OR = 2.361, 95%CI 1.095-5.092), interval since last miscarriage <6 months (OR = 2.154, 95%CI 1.246-3.726) and sleep disturbance (OR = 5.523, 95%CI 3.542-8.614) were associated with the occurrence of depressive symptoms. At the same time, anxiety can be used as a predictor of depression. Recurrent pregnancy loss women have a certain degree of anxiety, depression, and sleep disturbance. Education level, interval since the last miscarriage <6 months, and sleep disturbance are risk factors for anxiety and depression. A history of pregnancy loss after 14 weeks and no living birth are also closely related to anxiety. Therefore, it is necessary to pay close attention to the psychological state of RPL women and provide appropriate psychosocial support to reduce the occurrence of negative emotions.

Depressive symptoms, racism, and school belonging: examining correlates of substance use behaviors among Black college students

College is a context in which Black adults are at heightened risk for substance use behaviors and subsequently more harmful consequences. Increasingly, scholars are recognizing that to better understand shifts in patterns of substance use behaviors and health disparities among Black adults, mental health and racism are important factors to consider. Racism is multidimensional; thus, research is needed to investigate its multiple forms. Currently, it is unknown how the occurrence of depressive symptoms and various racism experiences influence patterns of substance use behaviors among Black college students. Further, while school belonging is evidenced to promote better health outcomes during adolescence, research is needed to understand school belonging in relation to substance use among Black college students. Using latent profile analysis (LPA), we identify patterns of substance use behaviors among Black college students (N = 152) and examine whether depressive symptoms, racism experiences (i.e., racial discrimination stress, internalized racism, negative police encounters), and school belonging are associated with the unique patterns. Latent profiles included indicators of substance use behavior frequency. Four patterns emerged: 1) low substance use, 2) predominant alcohol use, 3) co-use, 4) high polysubstance use. Depressive symptoms, internalized racism, and negative police encounters were significant correlates of patterns of substance use behaviors. School belonging, specifically, participation in student, cultural, spiritual, and Greek organizations, was also associated with profile membership. Findings suggest a need to integrate a broader understanding of how mental health and racism impacts the lives of Black college students, in addition to processes for supporting school belonging.

Predicting depressive symptoms in middle-aged and elderly adults using sleep data and clinical health markers: A machine learning approach

ObjectivesComorbid depression is a highly prevalent and debilitating condition in middle-aged and elderly adults, particularly when associated with obesity, diabetes, and sleep disturbances. In this context, there is a growing need to develop efficient screening methods for cases based on clinical health markers for these comorbidities and sleep data. Thus, our objective was to detect depressive symptoms in these subjects, considering general biomarkers of obesity and diabetes and variables related to sleep and physical exercise through a machine learning approach. MethodsWe used the National Health and Nutrition Examination Survey (NHANES) 2015–2016 data. Eighteen variables on self-reported physical activity, self-reported sleep habits, sleep disturbance indicative, anthropometric measurements, sociodemographic characteristics and plasma biomarkers of obesity and diabetes were selected as predictors. A total of 2907 middle-aged and elderly subjects were eligible for the study. Supervised learning algorithms such as Lasso penalized Logistic Regression (LR), Random Forest (RF) and Extreme Gradient Boosting (XGBoost) were implemented. ResultsXGBoost provided greater accuracy and precision (87%), with a proportion of hits in cases with depressive symptoms above 80%. In addition, daytime sleepiness was the most significant predictor variable for predicting depressive symptoms. ConclusionsSleep and physical activity variables, in addition to obesity and diabetes biomarkers, together assume significant importance to predict, with accuracy and precision of 87%, the occurrence of depressive symptoms in middle-aged and elderly individuals.