In the sixth phase of the national programme “Governmental Programme for Improvement of Safety and Working Conditions” in 2023, three meetings of the Interdepartmental Commission for Maximum Admissible Concentrations and Intensities for Agents Harmful to Health in the Working Environment were considered, during which: eight documentations of the occupational exposure limit values, a position regarding the extension of the transitional period for the OEL for nitrogen oxide by 3 years for the underground mining and tunnel construction sector, the position of the Cobalt Institute, the Group Expert of Chemical and Dust Agents regarding the proposal of the ECHA Risk Assessment Committee (RAC) for OEL values for cobalt and its inorganic compounds (as Co) and the position of the regarding the exemption for nickel and lead compounds included in the annex to the Regulation of MAC and MAI of 2018. The Interdepartmental Commission for MAC and MAI adopted and submitted to the minister responsible for labour three proposals to amend the list of MAC and MAI in the following scope: introduction of occupational concentration values for five new chemical substances, leaving the current MAC value for the inhalable fraction of glyphosate (herbicide), extension by 3 years of the transitional period for the permissible concentration of nitrogen oxide in the underground mining and tunnel construction sector, i.e. until August 21, 2026, removal of exclusions regarding nickel and lead compounds included in the annex to the regulation on NDS and NDN of 2018 (implementation of Directive 2022/431/EU). The results of the Commission’s activities in 2023 were presented in three notes, communication No. XVI, a popular science publication, at the 23rd PTHP Symposium, and in a brochure entitled “Harmful factors in the work environment - limit values for carcinogenic/mutagenic, reprotoxic substances” as well as regular occupational health and safety training and in postgraduate studies.