Predicting droplet transport in the atmosphere is a major issue for a large number of dispersion problems such as spray cooling systems in streets, urban lawn sprinklers [Milesi et al., “Interferometric laser imaging for respiratory droplets sizing,” Environ. Manage. 36, 426–438 (2005)], and dispersion of virus such as COVID or from a terrorist attack [Balachandar et al., “Host-to-host airborne transmission as a multiphase flow problem for science-based social guidelines,” Int. J. Multiphase Flow 132, 103439 (2020)]. Here, we investigate the propagation of droplets issued from a source near the ground between square obstacles with different spacings. The aerodynamic field is determined by large eddy simulation coupled with an immersed boundary method for the obstacles. Droplets are tracked by a Lagrangian approach. An evaporation model is used to account for varying humidity conditions. Droplet concentration, mass flux, and deposition rates are obtained for different evaporation conditions and obstacle spacings. The results show high deposition rates on the internal wall of the first obstacle due to droplet advection by the reverse flow of the primary vortex. In addition to this, droplets may escape the canyon and propagate downstream as far as eight times the obstacle distance (8H). The concentration of air-borne droplets downstream the canyon is higher for smaller street canyon openings. When evaporation is accounted for, the ground-level droplet concentration may be reduced by up to 30% in the case of small canyon openings.