Introduction: Congenital heart disease (CHD) is the most prevalent congenital disability found in newborns. Many cases remain unknown until complications occur, usually in young adults. Transthoracic and Doppler echocardiography are modalities of choice for CHD detection, but these are limited in Indonesia. Electrocardiography (ECG) is a widely available and low-cost test. This study investigated the role of ECG as a screening modality for CHD. Methods: A cross-sectional study was held at Atma Jaya School of Medicine and Health Science from August to November 2019. Participants were students aged 18 years old or more. Exclusion criteria was previously detected for CHD. Data were collected through history taking, anthropometrics, blood pressure measurement, and 12 leads ECG. ECG results were interpreted independently by two cardiologists to minimize observer bias. Results: A total of 193 students, 78 male and 115 female, participated. The mean age was 19.22±1.85 years. ECG abnormalities were discovered in 57 (29.5%) participants:15 with crochetage sign, 13 right axis deviation, three left axis deviation, nine right ventricle hypertrophy, and nine left ventricle hypertrophy, six left bundle branch block, and two defective T wave. Further evaluation was done with echocardiography in 20 participants, which resulted in one participant having mitral valve prolapsed (MVP). Conclusion: ECG could detect the characteristic patterns suggestive of CHD, but ECG alone is insufficient to confirm cardiac structural abnormalities.