The article is aimed at solving the actual problem of studying the factors of internal and external environment of functioning of sectoral structures. The authors analyzed an aggregate of various indicators for assessing the factors of development of sectoral structures using methods of multivariate statistical analysis. The completeness of the theoretical description of objects and objectivity of conclusions during the study of the problem of factor analysis of functioning of the mechanism of management of sectoral structures has been achieved. The problem of analysis of resource and investment-innovation factors of development of sectoral structures using factor analysis is examined. It is proposed to quantify the efficiency of functioning of the mechanism of enterprise management to use indicators of assessment of resource and investment-innovation potentials, which should be considered as indicators of outputs of the production system, transformed and obtained as a result of the influence of the management mechanism. The analysis was carried out in two directions: resource and investment-innovation. A large number of indicators characterizing the state of the internal and external environment of enterprises were processed, and using the methods of factor analysis, they were replaced with a certain set of uncorrelated parameters, which allowed to reduce the dimension of the studied totality of data. The state of resource and investment-innovation potentials of enterprises was considered as a result of the influence of the management mechanism, taking into account industry affiliation, that is, separately for enterprises of mechanical engineering, light or food industries. As result of the analysis, the following general factors were formed for light industry enterprises: economic direction of capital use; efficiency of use of the labor and material resources; efficiency of use of the equity and borrowed capital; efficiency of use of the borrowed funds. For food industry enterprises, the following factors are formed: the economic direction of capital use; efficiency of the financial and production activities; the ability of the management mechanism to provide a stable amount of profit; efficiency of use of fixed assets. Within the terms of investment and innovation direction for mechanical engineering and light industry enterprises, the most important factor is that which can be interpreted as the efficiency of research activities, the less important factor – the direction of using own investments for innovation; of the smallest importance is the direction of using investment resources for the production of innovative products.