Anisic Acid Research Articles

Integrating 16S rRNA Sequencing and LC⁻MS-Based Metabolomics to Evaluate the Effects of Live Yeast on Rumen Function in Beef Cattle.

Simple SummaryLive yeast products are used in ruminant nutrition to improve feed efficiency and performance. The effects of yeast on animal performance are mediated via alteration in the rumen microbial population and fermentation; however, the types of metabolites produced from feeding yeast additives have not been described. This study integrated 16S rRNA sequencing and LC–MS-based metabolomics to evaluate rumen bacterial diversity and metabolome of beef steers fed no or 15 g/d of live yeast product. Our findings confirm that live yeast supports the growth of fiber digesters, optimizes the utilization of oxygen and lactic acid, and inhibits the growth of pathogenic Salmonella in the rumen. In addition, some bacteria with unknown functions in relation to the effects of live yeast showed positive correlations with metabolites involved in the metabolism of amino acid and energy substrates. This study enhances our understanding of the effects of live yeast in the rumen.We evaluated the effects of live yeast on ruminal bacterial diversity and metabolome of beef steer. Eight rumen-cannulated Holstein steers were assigned randomly to one of two treatment sequences in a study with two 25-d experimental periods and a crossover design. The steers were housed in individual pens. The dietary treatments were control (CON) or yeast (YEA; CON plus 15 g/d of live yeast product). Bacterial diversity was examined by sequencing the V3-V4 region of 16S rRNA gene. The metabolome analysis was performed using a liquid chromatograph and a mass spectrometry system (LC–MS). Live yeast supplementation increased the relative abundance of eight cellulolytic bacterial genera as well as Anaerovorax and Lachnospiraceae. Proteiniclasticum, Salmonella, and Lactococcus were not detected in the YEA treatment. Live yeast supplementation increased the concentrations of 4-cyclohexanedione and glucopyranoside and decreased the concentrations of threonic acid, xanthosine, deoxycholic acid, lauroylcarnitine, methoxybenzoic acid, and pentadecylbenzoic acid. The bacteroidales BS11, Christensenellaceae R-7, and Candidatus saccharimonas showed positive correlations with the metabolites involved in amino acid biosynthesis and the metabolism of energy substrates; the functions of these bacteria are not fully understood in relation to the mode of action of yeast. This study confirms the usefulness of LC–MS-based metabolomics in deciphering the mode of action of live yeast in the rumen.

Abraham model correlations for describing solute transfer into 4-methyl-2-pentanol from both water and the gas phase

Experimental mole fraction solubilities have been determined for benzoic acid, 4-tert-butylbenzoic acid, 4-chlorobenzoic acid, 2-chloro-5-nitrobenzoic acid, 4-methoxybenzoic acid, salicylamide, 2-ethylanthraquinone, 3,5-dinitrobenzoic acid, 1,4-dichloro-2-nitrobenzene, sorbic acid, 1,4-dibromobenzene and 4-chloro-1-bromobenzene dissolved in 4-methyl-2-pentanol at 298 K. Solubilities were determined using a spectrophotometric method based on the Beer-Lambert law. Abraham model correlations were derived by combining the measured solubility data determined in the present study with published experimental values taken from our earlier publications. Fifty experimental data points were used in determining the Abraham model correlations presented in this study. The mathematical expressions were found to back-calculate the observed solubility to within standard deviations of 0.113 log units (or less).

Development of Abraham model correlations for solute transfer into 2-ethyl-1-hexanol from both water and the gas phase based on measured solubility ratios

ABSTRACTExperimental solubilities have been determined by spectrophotometric methods for 1-chloro-4-bromobenzene, 1,4-dibromobenzene, 1,4-dichloro-2-nitrobenzene, benzoic acid, 4-nitrobenzoic acid, 3,5-dinitrobenzoic acid, 2-methoxybenzoic acid, 4-methoxybenzoic acid, 3-chlorobenzoic acid, 3,5-dinitro-2-methylbenzoic acid, 2-methylbenzoic acid, 3-methylbenzoic acid, 3,4-dichlorobenzoic acid, benzoin, 4-tert-butylbenzoic acid, 4-chlorobenzoic acid, 3,4-dimethoxybenzoic acid, 3,4,5-trimethoxybenzoic acid and o-acetoacetaniside dissolved in 2-ethyl-1-hexanol at 298.15 K. Our experimental measurements, combined with published solubility data retrieved from the published chemical and engineering literature, were used to derive Abraham model correlations for solute transfer into 2-ethyl-1-hexanol from both water and from the gas phase. The derived Abraham model correlations were found to back-calculate the measured experimental values to within ±0.12 log units (or less).

Conformational equilibria in o-anisic acid and its monohydrated complex: the prevalence of the trans-COOH form.

The conformation of ortho-anisic acid and its monohydrated clusters generated in a supersonic jet has been studied by rotational spectroscopy to analyze the structural implications of ortho substitution. The dominant monomer species shows a trans-COOH arrangement stabilized by an intramolecular O-HO hydrogen bond from the acid to the methoxy group. The spectra of two non-planar skeleton monomer forms with a cis-COOH arrangement have also been detected. A tunneling doublet has been observed for the most stable cis-COOH conformer. The periodic potential energy function for the COOH internal rotation connecting these cis forms has been estimated from the experimental data. For the first time a water complex with an acid in a trans-COOH configuration has been observed. This is more abundant than the other weak form observed for the complex, characterized by a cis-COOH arrangement. The observation of the rotational spectra of salicylic acid, methyl salicylate and methyl 2-methoxybenzoate, formed upon heating of ortho-anisic acid, gives additional interest in the chemistry of ortho substituted benzoic acids.

Molecular Spectroscopy Evidence of Effective Constituents in the Binding of Angelica sinensis to Bovine Serum Albumin: Comparative Binding and Thermodynamic Profile

Some bio-effective constituents, such as organic acids and phthalides, from the root of Angelica sinensis can be observed in the blood after oral intake. In this work, two organic acids, ferulic acid and anisic acid, and two phthalides, senkyunolide I and butylidenephthalide, were selected to investigate the interaction with bovine serum albumin systematically, using a fluorescence spectroscopic method under physiological conditions. The Stern–Volmer quenching constant, binding constant, and the corresponding thermodynamic parameters and binding numbers were measured. Synchronous fluorescence and three-dimensional fluorescence spectroscopy were also used. The results provided molecular spectroscopy evidence that some constituents of Angelica sinensis are absorbed and transported into the blood.

The GC MS Study of one Ayurvedic Medicine, Vasakadyaristam

The present study deals with the GC MS analysis of one Ayurvedic prepaation, Vasakadyarishtam, which is a mucolytic medicine used for the treatment of cough, cold, chest congestion asthma and related diseases like bronchitis, inflammation and hemoptysis. The most important constituent of this medicine is Vasaka or Adhatoda vesika plant, which is known for its anti-cough and cold usage in Ayurveda. This study was to understand the main biomolecules present in this medicine by GC MS analysis. The results indicted the presence of some important molecules such as Eucalyptol, Phenylethyl alcohol, Camphor, Ethyl hydrogen succinate, Succinic acid, cyclobutyl ethyl ester, 3-Cyclohexen-1-ol, 4-methyl-(1-methylethyl)-(R)-,. alpha.-Terineol, 5-Hydroxymethyl furfural, p-Anisic acid, 4-nitrophenyl ester, 2-Propen-1-0l, 3-phenyl, Benzeneethanol, 4-hydroxy-Propiophenone, 2‘-(trimethylsioxy)-, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester and Octadecanoic acid and 2, 3-dyhydroxypropyl ester. These molecules are known for their various medicinal properties which indicate their roles in this formulation.

Abraham model correlations for solute transfer into benzyl alcohol from both water and the gas phase

ABSTRACTExperimental solubilities have been determined for anthracene, benzil, 2-chloroanthraquinone, 9-fluorenone, 2-hydroxybenzoic acid, 2-methoxybenzoic acid, 2-methylbenzoic acid, 3-methylbenzoic acid, phenothiazine, pyrene, and thioxanthen-9-one dissolved in benzyl alcohol at 298.15 K. The measured solubility data, combined with previously published activity coefficient and solubility data, are used to determine Abraham model correlations for solute transfer to benzyl alcohol from both water and from the gas phase. The derived Abraham model correlations were found to back-calculate the experimental partition coefficients and solubility ratios to within 0.14 log units (or less).

Two novel Sm(III) complexes with different aromatic carboxylic acid ligands: Synthesis, crystal structures, luminescence and thermal properties

Two novel Sm(III) complexes, [Sm(3,4-DMBA)3(3,4-DMHBA)(5,5′-DM-2,2′-bipy)]2 (1), [Sm(3-MOBA)3(5,5′-DM-2,2′-bipy)]2 (2) (3,4-dimethylbenzoic acid = 3,4-DMHBA, 3-methoxybenzoic acid = 3-MOHBA and 5,5′-dimethyl-2,2′-bipyridine = 5,5′-DM-2,2′-bipy), have been successfully synthesized and assembled. The crystal structures were determined by single crystal X-ray diffraction. Two complexes were characterized by the elemental analysis, IR, powder X-ray diffraction, thermal gravimetric technology. Because of the different ligands, the structures of the two complexes are very different, especially the structure of the complex 1. Each central Sm(III) ion of complex 1 was coordinated by three deprotonated 3,4-DMBA−,one unprotonated 3,4-DMHBA and one 5,5′-DM-2,2′-bipy, which has rarely been reported before. However each central Sm(III) ion of complex 2 was only coordinated via three deprotonated 3-MOBA− and one 5,5′-DM-2,2′-bipy. In addition, the thermal decomposition mechanism and the three-dimensional infrared accumulation spectra of the evolved gas during the thermal decomposition for two complexes were studied by the simultaneous TG/DSC-FTIR technology. What′s more, the luminescence properties of two complexes were also discussed. Finally, the bacteriostatic activities of two complexes were evaluated against Staphlococcus aureus, Escherichia coli and Candida albicans.

Tendency of using different aromatic compounds as substrates by 2,4-DNT dioxygenase expressed by pJS39 carrying the gene dntA from Burkholderia sp. strain DNT

The substrate range of 2,4-dinitrotoluene (DNT) dioxygenase was investigated by measuring substrate-dependent O2 uptake and maximum growth (expressed in A600) on substrate-containing minimal medium. The control for each strain had no added particular substrate. The following aromatic compounds: catechol, α-naphthalene acetic acid, β-dimethylaminobenzaldehyde, 3,4-dinitrosalicylic acid, p-nitrophenol, naphthanol, o-anisic acid, salicylic acid, toluene, and benzoic acid, were tried as possible substrates. Considering all substrates used, only p-nitrophenol showed zero oxygen uptake rate and zero growth. This indicates that it was rather unlikely that p-nitrophenol is a substrate analog for 2,4-DNT. Catechol was clearly used as a sole carbon source by both wild-type Escherichia. coli (JM103) and the dnt transformant (JS39). Using α-naphthalene acetic acid and β-dimethylaminobenzaldehyde as substrates resulted in DNT dioxygenase oxygen uptake rates of 11.8 and 14 μM/hr/mg protein, respectively. However, using both compounds as a carbon source, JS39 had twice the growth rate of E. coli JM103. For the remaining six substrates tested (3, 4-dinitrosalicylic acid, p-nitrophenol, o-anisic acid, salicylic acid, toluene, and benzoic acid), there appeared to be growth advantages for JS39 (even though the growth in the presence of substrate was less than the controls) suggesting a situation similar to that described for α-naphthalene and β-dimethylaminobenzaldehyde above. Combining results from our assay with respirometry and growth-based experiments will allow a better understanding of the biochemical consequences of these interactions. These results suggest that DNT dioxygenase gene, dntA carried by JS39, and those potential genes for substrates-degraded enzyme(s) system could have a common root.

Effect of various culture conditions on shoot multiplication and GC–MS analysis of Plumbago zeylanica accessions for plumbagin production

Plumbago zeylanica, a pharmaceutically important medicinal plant, contains a wide range of phytocompounds. Culture parameters like carbon source, nitrogen source, and culture media are essential for the development and growth of explants. In this investigation, the influence of various carbon sources (sucrose, glucose, and fructose at 3% concentration), nitrogen source (ammonium nitrate, sodium nitrate, and potassium nitrate) and plant tissue culture media (MS medium, Gamborg’s B5 medium, White medium and Nitsch medium) on shoot multiplication of five different accessions was studied. Optimum growth of all five accessions was observed in MS media containing 3% sucrose and ammonium nitrate as a source of carbon and nitrogen. Out of five accessions, IC-524441 showed the highest shoot multiplication. Further, methanolic extracts of all accessions (grown in MS media containing 3% sucrose and ammonium nitrate as nitrogen source) were prepared and comparison of extracts in DPPH assay indicated that accession number IC-524441 was the most effective free radical scavenging agent. Total phenolic, flavonoid and tannin content ranges were from 20 to 70 µg/ml, 40 to 100 µg/ml and 55 to 120 µg/ml, respectively, and the highest amount was found in accession number IC-524441. Sucrose and ammonium nitrate content may be responsible for increased antioxidant activity, flavonoids content, phenolic content, and tannin content in accession number IC-524441. GC–MS of ethyl acetate extract of all five accessions of P. zeylanica was conducted (grown in MS media containing 3% sucrose and ammonium nitrate as nitrogen source). GC–MS analysis of the aerial part showed the presence of various phytocompounds, which include 1,4-naphthalenedione, 3-eicosene, 5-eicosene, phthalic acid, o-anisic acid, thioctic acid, 1-octadecene, 5-t-butyl-cycloheptene, 2-benzoyl-1,2-dihydro-1-isoquinolinecarbonitrile, octadecanal, silane, 3-methoxy-2-methyl-2-(1-phenyl-ethylamino)-propionic acid, and 1-nonadecene. Accession number IC-524441 contains the highest amount of plumbagin, i.e. 14.19 ± 0.5 µg/ml as compared to the others.

Synthesis and Structure of Tetraphenylphosphonium Carboxylates

Hydrates of tetraphenylphosphonium carboxylates were synthesized by the reaction of equimolar amounts of pentaphenylphosphorus with 2-methoxybenzoic, 2-nitrobenzoic, and maleic acids in benzene. The product of the pentaphenylphosphorus reaction with tetrafluorophthalic acid (mole ratio 2: 1) is bis- (tetraphenylphosphonium) tetrafluorophthalate hydrate. According to the X-ray analysis data, crystals of tetraphenylphosphonim carboxylates are formed by tetraphenylphosphonim tetrahedral cations and single- or double-charged carboxylate anions. Structural organization of the crystals is determined by C–H···O weak hydrogen bonds formed with the participation of carboxylate groups and water molecules or manifold C–H···F interactions between cations and anions.

Formation of N-hydroxyphthalimide species in poly(vinyl-diisopropyl-phtalate ester-co-styrene-co-divinylbenzene) and its application in aerobic oxidation of p-methoxytoluene

Poly(vinyl-diisopropyl-phtalate ester-co-styrene-co-divinylbenzene) was synthesized by the bulk copolymerization process. Subsequently, isopropyl protecting groups were hydrolyzed followed by the ring closure. The consecutive reaction with hydroxylammonium chloride formed N-hydroxyphthalimide (NHPI) species. The expected chemical transformations were confirmed by elemental analysis, FT-IR, NMR and XPS. The prepared NHPI-containing material combined with Co(II) ions showed very high catalytic activity in the aerobic oxidation of alkylaromatics. After 6 h at 80 °C in the solvent-free system 22.5% of p-methoxytoluene was converted mainly into p-anisaldehyde, p-anisyl alcohol and p-anisic acid.

Synthesis, crystal structure and desulfurization properties of zig-zag 1D coordination polymer of copper(II) containing 4-methoxybenzoic acid ligand

ABSTRACTCombustion of fuels containing organosulfur compounds has resulted in the emission of sulfur oxides (SOx) into the atmosphere, therefore, causing serious environmental and health hazards. Herein, slightly distorted octahedral zig-zag 1D coordination polymer of copper(II) [Cu(4-mba)2(H2O)3] was synthesized by reacting copper sulfate pentahydrate with a carboxylate-containing ligand (H-4mba = 4-methoxybenzoic acid) and employed for sulfur compound uptake. The ligand coordinates to the copper(II) atom via two pairs of deprotonated ligating atoms (carboxylate oxygens) and two water molecules. Structural characterization also reveals that interplay of O–H···O, N–H···O, C-H···O and C–H···π interactions between lattice and coordinated water and ligands significantly contribute to the crystal packing leading to the formation and strengthening of three-dimensional supramolecular assembly. The complex, [Cu(4-mba)2(H2O)3], show potential for desulfurization of fuel with an observed adsorption capacity of 9.6 mg/g at 32°C for 6 h. DFT calculations further revealed a transfer of electron sulfur-containing compounds and the complex, [Cu(4-mba)2(H2O)3], thus leading to a stronger pi–pi interaction.

TOXICOLOGIC EVALUATION OF 2-METHOXYBENZOIC ACID AS A RISK FACTOR FOR WORKERS’ HEALTH.

The authors studied toxic properties of 2-methoxybenzoic acid for its hygienic regulation in the air of workplace. Values of average lethal dose (DL50) for male rats, male mice and female mice equal 5945, 3183 and 3030 mg/kg respectively. 2-methoxybenzoic acid is a highly dangerous substance (2nd jeopardy class). Clinical manifestations of the acute poisoning included adynamia, lower body temperature, tremor, periodic clonic and tonic convulsions. The chemical has average cumulative ability — cumulation coefficient is 3.03, with moderate irritative action on skin, but no skin resorption and sensibilizing activity, intense irritative influence on eyes mucosa (2nd jeopardy class). Acute inhalation action threshold is 33.9 mg/m 3 . Approximate safe level of exposure to 2-methoxybenzoic acid in the air of workplace is 0.5 mg/m 3 .

Co-crystal structures of 2,4-diamino-6-phenyl-1,3,5-triazine – 4-chlorobenzoic acid/4-methoxybenzoic acid: Synthesis, structural and Hirshfeld surface analysis

The co-crystal structure of 2,4-diamino-6-phenyl-1,3,5-triazine with 4-chlorobenzoic acid/4-methoxybenzoic acid molecules are explain the link between the dimension and shape of their hydrogen-bonded assembly. The co-crystal structure of 2,4-diamino-6-phenyl-1,3,5-triazine with 4-chlorobenzoic acid/4-methoxybenzoic acid forming a cyclic R22(8) ring motif via N–H⋯O and O–H⋯N hydrogen bonding interactions, to form a supramolecular heterosynthon. In both the co-crystal structures, self-association of 2,4-diamino-6-phenyl-1,3,5-triazine moieties are connected via N-H….N base pairs with cyclic R22(8) motif form a supramolecular homosynthon. In co-crystal II, the centrosymmetrically paired methoxy group of 4-methoxy benzoic acid form a supramolecular homosynthon via weak intermolecular C-H….O hydrogen bonds, generating R22(6) ring motif. Both the co-crystal structures are stabilized by weak aromatic π-π and C—Cl•••π stacking interactions. Hirshfeld surface and fingerprint plots were used to study the intermolecular interactions both of the crystal structures.

An Efficient and Improved Process for the Synthesis of Itopride Hydrochloride and Trimethobenzamide Hydrochloride

Aim and Objective: Itopride is a prokinetic agent used for treating conditions like non-ulcer dyspepsia. Itopride is administered as its hydrochloride salt. Trimethobenzamide is used for treating nausea and vomiting and administered as its hydrochloride salt. The aim is to develop a novel and environmental friendly method for large-scale production of itopride and trimethobenzamide. Materials and Methods: Itopride and trimethobenzamide can be prepared from a common intermediate 4- (dimethylaminoethoxy) benzyl amine. The intermediate is prepared from one pot synthesis using Phyrdroxybenzaldehye and zinc dust and further reaction of the intermediate with substituted methoxy benzoic acid along with boric acid and PEG gives itopride and trimethobenzamide. Results: The intermediate 4-(dimethylaminoethoxy) benzylamine is prepared by treating p-hydroxybenzaldehyde and 2-dimethylaminoethyl chloride. The aldehyde formed is treated with hydroxylamine hydrochloride. The intermediate is confirmed by NMR and the purity is analysed by HPLC. Conclusion: Both itopride and trimethobenzamide were successfully synthesized by this method. The developed method is environmental friendly, economical for large-scale production with good yield and purity.

Protective effect and mechanism of Muntingia calabura Linn. fruit ethanolic extract against vascular endothelial growth factor production in nickel-stimulated hepatocellular carcinoma cells

The protective effect of the M. calabura Linn. fruit ethanolic extract (MFEE) against nickel (Ni)-induced vascular endothelial growth factor (VEGF) expression in hepatocellular carcinoma (HepG2) cells was investigated. MFEE contained 4 flavonoids: epicatechin, rutin, diosmin and luteolin, and 11 phenolic acids: gallic acid, gentisic acid, p-hydroxybenzoic acid, vanillic acid, p-coumaric acid, ferulic acid, sinapic acid, syringic acid, p-anisic acid and rosmarinic acid. Substantial VEGF expression was assayed in Ni-stimulated HepG2 cells, which was significantly suppressed through MFEE treatment via down-regulating Raf-1 proto-oncogene, serine/threonine kinase (RAF1) /mitogen-activated protein kinase 1/2 (MEK1/2)/extracellular-signal-regulated kinase 1/2 (ERK1/2), and Janus kinase 2 (JAK2)/signal transducers and activators of transcription 3 (STAT3) pathways as well as inhibiting hypoxia-inducible factor (HIF)-1α expression down-regulated by phosphatidylinositol-3-kinase (PI3K)/ protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway. The results showed that MFEE should have the potential to lower liver cancer risk in the Ni-polluted environment by suppressing VEGF expression.

Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation

The cytochrome P450 enzymes execute a range of selective oxidative biotransformations across many biological systems. The bacterial enzyme CYP199A4 catalyzes the oxidative demethylation of 4-methoxybenzoic acid. The benzoic acid moiety of the molecule binds in the active site of the enzyme such that the functional group at the para-position is held close to the heme iron. Therefore, CYP199A4 has the potential to catalyze alternative monooxygenase reactions with different para-substituted benzoic acid substrates such as thioethers and alkylamines. The oxidation of 4-methyl- and 4-ethyl-thiobenzoic acids by CYP199A4 resulted in sulfur oxidation. 4-Ethylthiobenzoic acid sulfoxidation and 4-ethylbenzoic acid hydroxylation by CYP199A4 occurred with high enantioselectivity (>74% enantiomeric excess). By way of contrast, CYP199A4 catalyzed exclusive oxidative N-demethylation over N-oxide formation with 4-methyl- and 4-dimethylaminobenzoic acids. Unexpectedly acetamide formation by CYP199A4 competes with dealkyla...

Lanthanide complexes with 3-methoxybenzoic acid and 5,5′-dimethyl-2,2′-bipyridine: Crystal structures, luminescence and magnetic property

Five dinuclear trivalent lanthanide complexes, [Ln(3-MOBA)3(5,5′-DM-2,2′-bipy)]2 (Ln = Er(1), Ho(2), Eu(3), Pr(4), Nd(5); 3-MOBA = 3-methoxybenzoate; 5,5′-DM-2,2′-bipy = 5,5′-dimethyl-2,2′-bipyridine) have been successfully synthesized via conventional solution method at room temperature and structurally characterized by single crystal and powder X-ray diffraction. The molecular structures of complexes 1–5 are very novel-innovative. Complexes 1 and 2 were isomorphic, and the complex 1 was obtained with the coordination number of eight to form a distorted square-antiprism coordination geometry, while complexes 3–5 were nine-coordinated with a distorted monocapped square antiprismatic coordination geometry, but they can be all assembled into the same 1D, 2D supramolecular structure, which has rarely been reported previously. Over the temperature range of 300–1200 K, the thermal decomposition mechanism of complexes 1–5 were discussed by the technology of TG/DSC-FTIR. The luminescence spectra of complex 3 displayed the characteristic emission of Eu3+ ion (5D0 → 7F0-4), and it’s CIE coordinate was also calculated as (0.647, 0.341). In addition, the luminescence lifetime and intrinsic luminescence quantum yield were also investigated. Beyond that, the magnetic properties of complexes 1–2 were studied in detail.

Rare earth compounds with 3-methoxybenzoic acid and terpyridine ligands

Two trivalent rare earth compounds [Ln(3-MOBA)3(terpy)(H2O)]2 (Ln = Tb (1), Eu (2); 3-MOBA = 3-methoxybenzoate, terpy = 2,2′:6′,2″-terpyridine) were obtained in solid state, and the structure of 1 was determined by X-ray diffraction. The analysis of characterization was performed by elemental analysis, IR spectra, X-ray powder diffraction, thermogravimetric and differential scanning calorimetry coupled to infrared spectrometer (TG/DSC–FTIR). Besides that the luminescent properties and antibacterial activities were discussed. The crystal structure of 1 revealed that the asymmetric units were further stitched together to form 1D chain along the x-axis direction through the offset face-to-face π···π weak stacking interactions. Luminescence investigation revealed that compounds exhibited strong green and red emissions and the fluorescence quantum yield of two compounds were measured. What’s more, the Commission Internationale de L’Eclairage chromaticity diagrams were presented. The antibacterial activity studies show that two compounds had good antibacterial actions on E. coli, S. aureus and no antibacterial activities on C. albicans.