Nutrition Style Research Articles

Proteomic analysis of reserve proteins in commercial rice cultivars.

Rice consumption is rising in western countries with the adoption of new nutritional styles, which require the avoidance of gluten. Nevertheless, there are reports of rice allergic reactions. Rice grains contain a low amount of proteins most of which are storage proteins represented by glutelins, prolamins, albumins, and globulins. Some of these proteins are seed allergenic proteins as α‐amylase/trypsin inhibitor, globulins, β‐glyoxylase, and several glutelins. Italy is the major rice producer in Europe, and for this, seed reserve proteins of four Italian rice cultivars were characterized by 2D‐GE analysis. Some differentially abundant proteins were identified and classified as allergenic proteins, prompting a further characterization of the genes encoding some of these proteins. In particular, a deletion in the promoter region of the 19 KDa globulin gene has been identified, which may be responsible for the different abundance of the protein in the Karnak cultivar. This polymorphism can be applied for cultivar identification in commercial samples. Seed proteome was characterized by a variable combination of several proteins, which may determine a different allergenic potential. Proteomic and genomic allowed to identify the protein profile of four commercial cultivars and to develop a molecular marker useful for the analysis of commercial products.

Development and Validating of a Quest for Predicting Nutrition Literacy Promoting Behavior Based on the Theory of Planned Behavior in Southern Iran, 2017

Background: The evidence suggests nutrition style as a key determinant of health. On the other hand, nutrition literacy is a key determinant of nutrition decisions and behaviors. This study aimed to develop and validate an inventory in order to predict nutrition literacy promoting behavior based on the theory of planned behavior (TPB) in the youth. Methods: In this cross-sectional study, 203 students (100 females and 103 males) were selected using the randomized cluster method from dormitories in Shiraz University of Medical Sciences. They were supposed to complete Nutrition Literacy Promoting Behavior based on TPB (TPB-NLPB) questionnaire. The tool was developed using relevant scientific literature and its validity was confirmed by the experts’ panel (n = 6). The instrument includes four subscales: attitude toward behavior, subjective norm, perceived behavioral control, and behavioral intention. The reliability and validity of the instrument were assessed by exploratory and confirmatory factor analysis and Cronbach’s alpha coefficient. Results: The coefficients of Cronbach’s alpha (α = 0.87), Guttmann method (λ1 = 0.84 to λ6 = 0.91), and convergent validity (0.74) were estimated (P < 0.01). The exploratory factor analysis demonstrated five factors, which clarified 64.91% of the scale’s variance. Second-order confirmatory factor analysis pointed out that the factor was well matched up onto the principal factor. Consequently, the five-factor model was appropriate for the data using fit index techniques for adjusting the scale. Conclusions: The results confirmed the well-adjusted reliability and psychometric properties of the TPB-NLPB and its usefulness for the relevant studies.

Freaks or Foods: What motivates alternative nutrition and lifestyles?

AbstractGlobally, the adverse effects of increased animal-protein consumption on the environment, the society, and the economy are a cause of growing societal concern. As a result, issues of food system sustainability have received considerable attention within the national and international community. For the European community, changes in food lifestyles of consumers, in particular a reduced share of animal-based foods within the diet, are of great importance for the establishment of sustainable food supply structures. Meanwhile, a worldwide trend for alternative nutrition and lifestyles is obvious, which is reflected by a growing number of plant-based nutrition styles and craft-foods. Often, alternative nutrition styles are ethically or health motivated. Nonetheless, changes in regard to nutrition are often not consistent. Up to now, research mainly focused on the quantitative and qualitative aspects of food lifestyle changes. However, extreme, alternative nutrition lifestyles seem to be more disciplined with regard to nutrition transformation. Nonetheless, especially extreme food consumption patterns have not been assessed with regard to a long-lasting sustainable transformation potential. However, we propose that a comprehensive framework of these issues must contain information on the specific motivational themes that lead people to make substantial changes in their diets. Hence, the objective of the proposed study is to assess the transforming potential by in-depth interviews with extreme alternative nutrition styles. We aim in gathering knowledge on the content of the motivational dynamics influencing consumers in adapting alternative food lifestyles like raw-foodism, Paleolithic diet, or Anthroposophic diet. The theoretical framework applied is grounded in self-determination theory, a meta-theoretical construct used for explaining motivational change dynamics in humans. The research questions that will be addressed are: “What motivates people to adapt extreme alternative dietary styles?”, “How do identity and individual worldview influence the transition process?” and “Which strategies were applied to successfully implement new dietary habits into daily routine? In-depth interviews, following an experience interview will be conducted with 18 participants who had practiced an alternative food lifestyle for a long-term period. The transcripts of these interviews will be structured using content analysis. Since data collection will take place in May 2019 results cannot be described by deadline for the call of abstracts. Results and conclusion that will be addressed in the FENS Conference will include the motivational drivers for long-lasting transformation potential and discuss the applicability for society and behavior change communication.

Hematological impact in mice due to alteration in their nutritional style

Hematological impact in mice due to alteration in their nutritional style

Influencing factors on changes in nutritional behaviour over the life span

AbstractFrom an early age nutrition is part of everyday life, but the motives of eating change over the life span. The nutrition depends on many factors and is always embedded in an individual and social dimension. Especially life-phase-specific framework conditions and factors play an important role in the daily nutrition. The aim of this project was to find out how different factors affect nutritional behaviour in different age groups.The study was part of the research project “enable - healthy food choices in all stages of life”. In order to examine the factors influencing the nutritional behaviour, focus groups with young women and men, middle-agers and elderly had been implemented. In addition biographical interviews were conducted to gain a deeper insight into the reasons for changing the nutritional behaviour. Thus influencing factors and their weighting could be identified and their mode of action could be linked.For example, changes in the nutritional habits of adolescents could be figured out more accurately. Essential for young adults is the replacement of the parents, which is obtained by moving out of the parental home. An own lifestyle and nutritional style has to be developed and there are many changes and new freedoms and opportunities to try out. The consumption of fast food, for example, is particularly attractive to adolescents, as it is a distinction from the adult culture and rules of eating, like eating with cutlery. Another example is the nutritional situation of elderly, which is often characterized by malnutrition or disease-related dietary requirements. However, many elderly do not eat as recommended, even if they have the skills to implement it. In everyday life, deviations from the nutritional recommendations are often legitimized by the age itself “now I can indulge myself a bit”. Other legitimization factors include the death of the partner “I have been cooking my whole life, now I can just eat a sandwich”.The majority of people do not eat according to nutritional recommendations, too much sugar and salt and little fruits and vegetables characterize the nutrition. The consequences do not only concern health aspects such as nutritional diseases, but also ecological aspects. Despite knowing about the consequences of unhealthy food, many do not realize their knowledge about healthy eating in everyday life. If the nutritional situation should be improved sustainably, it is therefore necessary to include the individual factors and changes in the life span in considerations and concepts of nutritional programs.

Okul Öncesi Çocuklarda Ebeveyn Besleme Tarzı Ve Etkileyen Faktörler

Okul Öncesi Çocuklarda Ebeveyn Besleme Tarzı Ve Etkileyen Faktörler

Mediterranean diet and breastfeeding reduce the risk of gallstone in women

OBJECTIVE: This study aimed to determine the effect of nutrition style and breastfeeding on the formation of gallstone in women. METHODS: 50 women age from 40 to 69 included in the study. A questionnaire in which the participant’s general information questioned, their anthropometric values recorded, and the Mediterranean diet (MD) adherence scale included, was filled in by the face-to-face interview method. RESULTS: Body mass index (BMI), waist circumference (WC), diastolic blood pressure (DBP), fasting blood glucose (FBG), and serum C-reactive protein (CRP) values were higher in those with gallstones than in the control group. The total breastfeeding time and MD adherence scores were higher in the control group. It determined that there was a negative relationship between breastfeeding time with DBP and CRP. It found that an increase in BMI and WC increases the probability of gallstones. It found that an increase in the duration of breastfeeding and MD adherence score decreases the probability of the gallstones. CONCLUSION: Breastfeeding and Mediterranean diet reduce the risk of gallstones in women.

Vegan beslenme tarzına genel bakış

Vejetaryen beslenme, bitkisel kaynaklı besinlerin ağırlıklı tüketildiği, et ya da hayvansal kaynaklı gıdaların hiç tüketilmediği veya sınırlı olarak tüketildiği beslenme tarzıdır. Vejetaryen beslenme biçimleri lakto vejetaryen, ova vejetaryen, lakto-ova vejetaryen, polo vejetaryen, pesko vejetaryen, semi vejetaryen ve vegan olarak sınıflandırılabilmektedir. Vegan beslenme, hayvansal besinlerin tümünün tüketilmediği bir beslenme şeklidir. Vegan yaşam tarzını seçen bireyler hayvansal besinlerin yanında hayvan kaynaklı ipek, yün, deri ve kozmetik ürünleri de kullanmayı tercih etmezler. Bireylerin sağlıklarına olumlu etki yapabileceği düşüncesi, kültür, dini inançlar, etik ve biyoetik nedenler ile hayvanlara karşı duyarlı olmak gibi sebepler vegan yaşam tarzının seçilmesinde öncül faktörlerdendir. Çevreye olumlu etkilerinin yanı sıra, kalp-damar hastalıklarına ve kronik hastalıklara karşı koruyucu ve metabolik hastalık kaynaklı ölüm oranının düşürülmesinde etkili olabileceği gösterilen vegan beslenme şeklinin uzun süreli uygulanmasında besin ögesi yetersizliklerine bağlı olarak birtakım yan etkiler ve sağlık sorunları da gözlenebilmektedir. Vegan beslenme sebze ve meyveler, kuru baklagiller ve tahıllardan oluşur. Vegan bireylerde yetersiz ve dengesiz beslenme ile yüksek miktarda alınan posa miktarına bağlı olarak enerji ve protein dengesinde bozulmalar ile D vitamini, B12 vitamini, kalsiyum, demir, çinko gibi bazı vitamin ve minerallerin gereksinim düzeyinde karşılanamaması gibi problemler görülebilir. Ancak bireylerin doktor tarafından değerlendirilip, beslenme uzmanı tarafından yeterli ve dengeli bir beslenme programı düzenlendiği durumlarda bu olumsuz etkiler azaltılıp önlenebilir. Vegan beslenme tarzını benimseyen bireylerin sağlıklarının olumsuz etkilenmemesi amacıyla bu bireylerin sağlık çalışanları tarafından doğru ve güncel konu ve uygulamalarla bilgilendirilip yönlendirilmeleri gerekmektedir. Bu derlemede amaç vegan beslenme ile ilgili literatürdeki verilerin incelenmesidir.

ЕFFICIENCY OF CORRECTING LIPID AND METABOLIC IMBALANCE IN PATIENTS WITH MORBID OBESITY BY PHYSIOTHERAPY METHODS

The program of physiotherapy of persons with morbid obesity has been developed and proposed for implementation. Objective: To determine the dynamics of dyslipidemia indices and metabolic disorders in patients with morbid obesity under the influence of a physiotherapy program. Меthods. Analysis of scientific literature, examination and testing. Results. A total of 74 persons with morbid obesity were examined and divided into a comparison group and a main group according to compliance value and 63 persons without signs of obesity. Anthropometric parameters (height, weight, body mass index, waist and hip circumference, their ratio), parameters of energy metabolism (fasting blood glucose and after glucose loading), lipid profile (concentration of cholesterol, triglycerides, high density lipoproteins), visceral obesity index were evaluated. The examinations were conducted before and after the implementation of the annual physiotherapy program, which included maintaining highlevel rehabilitation compliance, increasing physical activity, changing nutrition style, reflexotherapy, massage, and psychocorrection. All persons with morbid obesity were diagnosed with abdominal obesity. Analysis of glucose profile parameters revealed fasting hyperglycemia and impaired glucose tolerance. Atherogenic disorders of the lipid spectrum were determined: high levels of total cholesterol and triglycerides; low levels of low density lipoproteins. The visceral obesity index was almost 10 times higher than that of people with normal body mass. Annual adherence to the principles of the developed program in the face of high level of compliance allowed to achieve a statistically significant (p < 0.05) improvement over the baseline indices of all the studied parameters of the main group subjects. Their weight loss was more than 20 %, body mass index reached the parameters of I obesity degree, the degree of abdominal obesity decreased (p < 0.05). Fasting glucose was normalized, tissue sensitivity to glucose was restored. There were positive changes in the concentrations of atherogenic lipid fractions; the visceral obesity index improved.

Histological impact of nutritional style alteration in mice

Objectives: It is well established that diet and lifestyle are important in maintenance of healthy. Transition from a plant-based diet mostly to a high-calorie diet of animal products might raise the chronic diseases which called “degenerative”. This work aimed to study the histopathological effect of transition from complete plant-based diet to 10% animal products (sheep’s brain) on various body organs of mice.
 Methods: Eight-week old Balb/c male mice were divided into 2 groups (n=8); the first is restricted group in which mice were fed on restricted diet containing 10% of sheep’s brain homogenate, while the second is the control group in which fed on ad libitum on the diet for 7 days. During the duration of experiment, body weight and the amount of food intake were recorded daily, then at the end of experiment, all mice were sacrificed and various organs were obtained and processed for histopathological study.
 Results: the results showed that food intake by each mouse of restricted group are significantly lower than in control group. Although the mean of body weight in both groups revealed non-significant difference, the relative weight of various organs showed significant differences. On the other hand, sever histological changes were detected in all studied organs sections of restricted group.
 Conclusion: It can be concluded that changing in nutritional style rather than conventional diet play a crucial role in modifying the architectural aspects of different organs at tissue level. Therefore, these findings need further investigation at cellular, physiological, and molecular levels.

The influence of plant-based nutrition and level of oestrogen on life satisfaction

Previous studies have shown that people benefit more from vegetarian or vegan diets than from an omnivorous diet, not only in physical but also in mental health. Studies have also reported substantial evidence that particular disorders can be triggered by preferred food choices. For example, consumption of animal products increases the intake of arachidonic acid which can induce depressive moods. On the other hand, nutrition can have positive effects, e.g. polyunsaturated N-3 fatty acids have several somatic health benefits not only on cardiovascular diseases, but also on depression. Similarly, a diet with a high content of tryptophan (a serotonin predecessor) can change mood by altering the synthesis of different neurotransmitters. In this pilot study, (i) omnivores (n=45), (ii) vegetarians (n=13) and (iii) vegans (n=7) were compared for their levels of satisfaction in everyday life, as measured on the Oxford Happiness Scale. The effect of oestrogen was analysed as a confounding variable. Between the three styles of nutrition, only small differences were found. All groups achieved an average of more than 4 points on a 6-stage Likert-scale (1=not happy, 6 = very happy), which lies in the range of moderately happy. The mean score of all three groups was 4.30 ±0.84. The difference between the omnivore, (4.23 ±0.69) and the vegetarian groups, (4.29 ±1.24) was very small, but the vegan group achieved a score well above 5, (5.20 ±0.17). In an ANCOVA, the effect of nutrition style on happiness was close to being significant, [p=0.066]. In addition, estimated oestrogen level had significant effects on satisfaction in everyday life, [p=0.047]. Conclusion: Further research on a larger sample is justified to determine if life satisfaction is influenced by nutrition style when controlled for oestrogen levels.

Prevalence of aeroallergens and food allergens in allergic patients in Tehran, Iran

Background and Aims: Identification of different allergens is a major challenge in allergic diseases. Avoiding these allergens is known as one of the best types of treatment. The aim of this study is to determine the prevalence of aeroallergens and food allergens in patients with allergy by Skin Prick Test. Materials and Methods: A cross-sectional study was conducted on 255 patients with allergic diseases who had referred to the Khorshid Allergy and Immunology Clinic. Skin Prick Test was performed using 82 allergen extracts to determine the patients' sensitivity to food and aeroallergens. Results: One hundred percent of the patients were sensitive to at least one allergen. Allergy to food allergens and aeroallergens was 49% and 51 %, respectively. Most sensitivity to food allergens included hazelnut (26.27%), bananas (21.96%), egg yolk (21.56%) and wheat (20.39%). Among the aeroallergens, grass with a frequency of 87% and fungi with a frequency of 34% had the highest and lowest frequencies. Conclusion: Depending on the nutrition, cultural habits, environmental conditions, and life style, prevalence of the allergens in each area may be different. Therefore, early identification and avoidance from these allergens can be suggested.

Style żywieniowe Polaków i ich społeczno-demograficzne uwarunkowania

ABSTRAKTWstęp: Sposób odżywiania należy do modyfikowalnych czynników ryzyka chorób i jest jednym z przedmiotów edukacji zdrowotnej. Jego zmiana może być trudna, ponieważ jedzenie nie tylko służy zaspokojeniu potrzeb fizjologicznych, lecz także jest elementem stylu życia, który definiuje się jako spójną całość obejmującą zachowania wybierane przez ludzi w zakresie, w jakim pozwala im na to ich ulokowanie w strukturze społecznej. Różne praktyki żywieniowe mogą stanowić elementy różnych stylów życia.Celem analizy była identyfikacja stylów żywieniowych Polaków oraz ich społeczno-demograficznych uwarunkowań.Materiały i metody: Dane zebrano w 2016 r. za pomocą wywiadu kwestionariuszowego bezpośredniego na ogólnopolskiej próbie reprezentatywnej (n = 1000). Wykonano analizę głównych składowych oraz analizę regresji liniowej wielokrotnej.Wyniki: Zidentyfikowano trzy style żywieniowe – „niedbały”, „prozdrowotny” i „tradycyjny”. Styl „niedbały” jest typowy dla mężczyzn, osób młodszych oraz ludzi żyjących w większych gospodarstwach domowych. Rzadziej cechują się nim specjaliści, wykonawcy wolnych zawodów i kierownicy, a także uczniowie i studenci, emeryci i renciści oraz mieszkańcy najmniejszych miast. Styl „prozdrowotny” charakteryzuje przeważnie kobiety, osoby z wykształceniem wyższym i średnim, uczniów i studentów, a także przedsiębiorców. Styl „tradycyjny” częściej cechuje osoby młodsze, mieszkające w mniejszych gospodarstwach domowych, z wykształceniem średnim i zasadniczym zawodowym, a także mieszkańców miast liczących 50 000–200 000 mieszkańców.Wnioski: Analiza wskazuje na istnienie stylów żywieniowych związanych z ulokowaniem w strukturze społecznej, co powinno być uwzględniane w edukacji zdrowotnej w zakresie żywienia.

Fibres as functional foods and the effects on gut hormones: The example of β-glucans in a single arm pilot study

Nutritional styles as Mediterranean and DASH diets are associated with lower incidences of certain chronic diseases and long life expectancy. The reason lays on their different contribution in fibers, polyphenols (from vegetables and fruit) and proteins. Barley is high fiber cereal that contains high amount of β-glucans and insoluble fibers that it was recognized having healthy benefits.The aim of the study was to evaluate the effects of β-glucans intake on glycaemic response, cholesterol and intestinal hormones levels. A single arm pilot study was performed with ten healthy individual which, consumed pasta enriched with 6% β-glucans for 30 days. Blood was collected at fasting and at multiple intervals until 180 min after the test meal consumption. The results showed that pasta modify plasma levels of gut hormones and low density lipoprotein levels.These results add another piece of evidence to the role of the alimentary interventions to preserve healthy status.

Effect of Reflexology on Infantile Colic.

The aim of this study was to explore the effect of reflexology on infantile colic. A total of 64 babies with colic were included in this study (n = 31: study group; n = 33: control group). Following a pediatrician's diagnosis, two groups (study and control) were created. Sociodemographic data (including mother's age, educational status, and smoking habits of parents) and medical history of the baby (including gender, birth weight, mode of delivery, time of the onset breastfeeding after birth, and nutrition style) were collected. The Infant Colic Scale (ICS) was used to measure the colic severity in the infants. Reflexology was applied to the study group by the researcher and their mother 2 days a week for 3 weeks. The babies in the control group did not receive reflexology. Assessments were performed before and after the intervention in both groups. The groups were similar regarding sociodemographic background and medical history. While there was no difference between the groups in ICS scores before application of reflexology (p > 0.05), the mean ICS score of the study group was significantly lower than that of control group at the end of the intervention (p < 0.001). Reflexology application for babies suffering from infantile colic may be a promising method to alleviate colic severity.

A comparison of physical activity and nutrition in young women with and without primary dysmenorrhea

Background: Dysmenorrhea is the most common gynecological disorder in young women and is seen in almost 50% of women. The present study was conducted to investigate the relationship between physical activity and nutrition with primary dysmenorrhea in students at Mazandaran University of Medical Sciences (Sari, Iran) in 2015. Methods: This comparative descriptive study was conducted on 250 students with and without primary dysmenorrhea. Data were collected using personal-demographic, nutrition and physical activity questionnaires. The output was then analyzed in SPSS-18 using independent t-test, Chi-square test and logistic regression analysis. Results: The results showed significant differences between the two groups in terms of nutrition and physical activity, as the mean score of nutrition was 57.91 in the group with dysmenorrhea and 61.68 in the group without, while the mean intensity of physical activity was 5518.75 metric in the group with dysmenorrhea and 4666.42 metric in the group without. Physical activity was calculated by MET scale (minutes/week). This index measured the amount of consumed energy at the time of activity relative to that consumed at resting time. Conclusions: A healthier and more favorable nutrition style and more regular physical activity reduces the severity of dysmenorrhea in girls. Therefore, educational measures are required to raise awareness among young women about the effects of proper nutrition and physical activity on the prevention and reduction of dysmenorrhea complications.

A study to assess the impact of home based education on life style modification among adults with diabetes mellitius at Selected Villages in Kancheepuram District, Tamil Nadu, India

The aim of the study is to educate the adults with diabetes mellitus on low carbohydrate diet and to evaluate the impact of home based education on lifestyle changes. With single blindered randomized controlled trial and self structured interview questionnaire the data was collected among 400 (200 study +200 control) diabetic subjects in Maraimalai Nagar and 9 villages around Kancheepuram district. After the baseline screening the study group subjects were educated with low caloric diet menu plan according to BMI, and a booklet on all aspects of managing diabetes mellitus was also issued to them. Nutritional counseling was given every 15 days for 3 months. The post test revealed an absolute reduction in history of smoking (p<0.001), history of drinking (P<0.001) and history of eating out side food (p<0.03) compared to control group. Eating rice for breakfast was reduced and eating chapatti was increased among the intervention group with (p<0.001). Overall the finding of the study concludes there are significant changes on life style practice after individual video teaching and dietary counseling among the intervention group. The study suggested that nutritional counseling and healthy life style factors must be taught by all health care professionals to increase awareness and to control diabetes mellitus among Indian population.

An Insight into Family and Social Relationships of Day Workers and Shift Workers in Visakhapatnam

The present study was carried out to assess and compare the health problems experienced by day and shift workers in Visakhapatnam. The research was conducted on a sample of 70 software engineers, in the age group of 22-33 years in Bhubaneshwar, Orissa. Health is a state of complete physical, mental and social well being and not merely an absence of disease. It provides the ability to lead a socially and economically productive life. So a healthy individual is free from disease; in a state of normal functioning. As shift work is a phenomenon of 24 hours continuous operations, the effect of shift work on health was assessed in terms of nutritional anthropometry and life style indicators. Majority of shift workers were reported to become workaholic. Majority of shift workers reported impairment in social leisure activities, personal leisure, activities and ability to form and maintain close relationship with family members compared today workers.

Prevalence and characteristics of orthorexia nervosa in a sample of university students in Italy.

Orthorexia nervosa (ON) has been recently defined as a pathological approach to feeding related to healthiness concerns and purity of food and/or feeding habits. This condition recently showed an increasing prevalence particularly among young adults. In order to investigate the prevalence of ON and its relationship with gender and nutritional style among young adults, we explored a sample of students from the University of Pisa, Italy. Assessments included the ORTO-15 questionnaire and a socio-demographic and eating habits form. Subjects were dichotomized for eating habits (i.e. standard vs vegetarian/vegan diet), gender, parents' educational level, type of high school attended, BMI (low vs high vs normal BMI). Chi square tests were performed to compare rates of subjects with overthreshold ORTO-15 scores, and Student's unpaired t test to compare mean scores between groups. Two Classification tree analyses with CHAID growing method were employed to identify the variables best predicting ON and ORTO-15 total score. more than one-third of the sample showed ON symptoms (ORTO-15 ≥ 35), with higher rates among females. Tree analyses showed diet type to predict ON and ORTO-15 total score more than gender. Our results seem to corroborate recent data highlighting similarities between ON and anorexia nervosa (AN). We propose an interpretation of ON as a phenotype of AN in the broader context of Feeding and eating disorders (FEDs) spectrum.

Efficacy of Traditional Persian Medicine-Based Diet on Non-Alcoholic Fatty Liver Disease: A Randomized, Controlled, Clinical Trial

Background: Regarding the preventive approaches of traditional Persian medicine (TPM) in the management of chronic diseases such as fatty liver, we evaluated the effect of a TPM-based nutritional style on liver enzymes levels and fatty liver grade in patients with non-alcoholic fatty liver. Materials and Methods: Patients were randomly assigned to receive either a three-month TPM-based diet as the intervention group or received the low-fat, low-calorie diet as the control group. The primary outcome measure was changes in serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Secondary outcome measures were changes in fatty liver grade (fatty tissue infiltration in liver by using ultrasound imaging) and changes in patients’ body mass index (BMI). All outcome measures were evaluated at the baseline, at six weeks, and at three months after intervention. Results: Regarding within-group changes in outcome measures’ mean values, there was a significant reduction in ALT serum level, AST, BMI, and fatty liver grade after intervention, compared with baseline in both groups of study (P&lt; 0.001). The results of between-group analyses showed significant decreases in both mean body mass index and mean fatty liver grade between the intervention group compared to the control group at the end of intervention (P&lt;0.037 and P&lt;0.003, respectively). Conclusion: This randomized open-label controlled clinical trial demonstrated that the traditional Persian medicine-based nutritional style, used as a non-pharmacological remedy, could reduce body weight and improve fatty liver grade in patients suffering from non-alcoholic fatty liver disease. [GMJ.2017;6(3):208-216] DOI:10.22086/gmj.v6i3.813